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Nanostructured zinc oxide materials are capturing a great deal of interest thanks to their outstanding and multifunctional properties, enabling broad series of intervention in the field of nanomedicine. ZnO can be easily prepared in a broad variety of shapes and shows anticancer and antimicrobial properties that are of interest for tissue engineering, controlled delivery of therapeutics, and even theranostics. This book is thus dedicated to the most recent advances in the field, presented as a collection of research papers and reviews. It spans from the synthesis and characterization of ZnO nanomaterials to their applications in the nanomedicine field, ranging from anticancer nanotherapeutics to dental implants and antibacterial agents.

Technology: general issues --- ZnO nanoparticles --- Quantum dots --- theranostic --- drug delivery --- anti-tumour --- diabetes treatment --- anti-inflammation --- antibacterial --- antifungal --- wound healing --- denture stomatitis --- polymethylmethacrylate --- zinc oxide nanoparticles --- Candida albicans --- mesoporous glasses --- ZnO-additions --- osteostatin loading --- osteosteoblast cell cultures --- osteogenic effect --- zinc oxide --- microwave solvothermal synthesis --- hydrodynamic size --- surface chemistry --- nanocrystals --- cell cytotoxicity --- Supercritical CO2 --- ibuprofen --- NsZnO --- antimicrobial activity --- ZnO nanoparticles --- Quantum dots --- theranostic --- drug delivery --- anti-tumour --- diabetes treatment --- anti-inflammation --- antibacterial --- antifungal --- wound healing --- denture stomatitis --- polymethylmethacrylate --- zinc oxide nanoparticles --- Candida albicans --- mesoporous glasses --- ZnO-additions --- osteostatin loading --- osteosteoblast cell cultures --- osteogenic effect --- zinc oxide --- microwave solvothermal synthesis --- hydrodynamic size --- surface chemistry --- nanocrystals --- cell cytotoxicity --- Supercritical CO2 --- ibuprofen --- NsZnO --- antimicrobial activity

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Nanostructured zinc oxide materials are capturing a great deal of interest thanks to their outstanding and multifunctional properties, enabling broad series of intervention in the field of nanomedicine. ZnO can be easily prepared in a broad variety of shapes and shows anticancer and antimicrobial properties that are of interest for tissue engineering, controlled delivery of therapeutics, and even theranostics. This book is thus dedicated to the most recent advances in the field, presented as a collection of research papers and reviews. It spans from the synthesis and characterization of ZnO nanomaterials to their applications in the nanomedicine field, ranging from anticancer nanotherapeutics to dental implants and antibacterial agents.

ZnO nanoparticles --- Quantum dots --- theranostic --- drug delivery --- anti-tumour --- diabetes treatment --- anti-inflammation --- antibacterial --- antifungal --- wound healing --- denture stomatitis --- polymethylmethacrylate --- zinc oxide nanoparticles --- Candida albicans --- mesoporous glasses --- ZnO-additions --- osteostatin loading --- osteosteoblast cell cultures --- osteogenic effect --- zinc oxide --- microwave solvothermal synthesis --- hydrodynamic size --- surface chemistry --- nanocrystals --- cell cytotoxicity --- Supercritical CO2 --- ibuprofen --- NsZnO --- antimicrobial activity --- n/a

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This book entitled “Toxicology and Biocompatibility of Nanomaterials” covers some recent insights into adverse but beneficial effects of nanomaterials on human health and the environment. Renowned experts in the field contributed to this Special Issue to make this an interesting read for both scholars and students.

synthetic amorphous silica --- nanoparticles --- colon cells --- in vitro toxicity --- cell death --- biocompatibility --- circulating tumor cells --- metastasis --- microbubbles --- nanomedicine --- nanotechnology --- nanotoxicology --- European Chemicals Agency (ECHA) --- ecotoxicology --- aggregation --- Raphidocelis subcapitata --- air pollution --- Alzheimer’s disease --- amyloid --- Caenorhabditis elegans --- COVID-19 --- dementia --- neurotoxicology --- particulate matter --- serotonin --- tire wear --- silica --- SiO2 --- nanoparticle --- E551 --- toxicity --- genotoxicity --- macrophage --- intestine --- co-exposure --- nanosafety --- cytotoxicity --- inter-laboratory comparison --- best practice --- training --- nanomaterials --- titanium dioxide --- NALP3 --- interleukin-1beta --- NR8383 --- bone marrow derived macrophages --- zinc oxide nanoparticles --- diabetes --- hyperglycemic response --- zinc --- nanoparticle toxicology --- n/a --- Alzheimer's disease

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This book entitled “Toxicology and Biocompatibility of Nanomaterials” covers some recent insights into adverse but beneficial effects of nanomaterials on human health and the environment. Renowned experts in the field contributed to this Special Issue to make this an interesting read for both scholars and students.

Medicine --- synthetic amorphous silica --- nanoparticles --- colon cells --- in vitro toxicity --- cell death --- biocompatibility --- circulating tumor cells --- metastasis --- microbubbles --- nanomedicine --- nanotechnology --- nanotoxicology --- European Chemicals Agency (ECHA) --- ecotoxicology --- aggregation --- Raphidocelis subcapitata --- air pollution --- Alzheimer's disease --- amyloid --- Caenorhabditis elegans --- COVID-19 --- dementia --- neurotoxicology --- particulate matter --- serotonin --- tire wear --- silica --- SiO2 --- nanoparticle --- E551 --- toxicity --- genotoxicity --- macrophage --- intestine --- co-exposure --- nanosafety --- cytotoxicity --- inter-laboratory comparison --- best practice --- training --- nanomaterials --- titanium dioxide --- NALP3 --- interleukin-1beta --- NR8383 --- bone marrow derived macrophages --- zinc oxide nanoparticles --- diabetes --- hyperglycemic response --- zinc --- nanoparticle toxicology --- synthetic amorphous silica --- nanoparticles --- colon cells --- in vitro toxicity --- cell death --- biocompatibility --- circulating tumor cells --- metastasis --- microbubbles --- nanomedicine --- nanotechnology --- nanotoxicology --- European Chemicals Agency (ECHA) --- ecotoxicology --- aggregation --- Raphidocelis subcapitata --- air pollution --- Alzheimer's disease --- amyloid --- Caenorhabditis elegans --- COVID-19 --- dementia --- neurotoxicology --- particulate matter --- serotonin --- tire wear --- silica --- SiO2 --- nanoparticle --- E551 --- toxicity --- genotoxicity --- macrophage --- intestine --- co-exposure --- nanosafety --- cytotoxicity --- inter-laboratory comparison --- best practice --- training --- nanomaterials --- titanium dioxide --- NALP3 --- interleukin-1beta --- NR8383 --- bone marrow derived macrophages --- zinc oxide nanoparticles --- diabetes --- hyperglycemic response --- zinc --- nanoparticle toxicology

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Metal ions are fundamental elements for the maintenance of the lifespan of plants, animals and humans. Their substantial role in biological systems was recognized a long time ago. They are essential for the maintenance of life and their absence can cause growth disorders, severe malfunction, carcinogenesis or death. They are protagonists as macro- or microelements in several structural and functional roles, participating in many bio-chemical reactions, and arise in several forms. They participate in intra- and intercellular communications, in maintaining electrical charges and osmotic pressure, in photosynthesis and electron transfer processes, in the maintenance of pairing, stacking and the stability of nucleotide bases and also in the regulation of DNA transcription. They contribute to the proper functioning of nerve cells, muscle cells, the brain and the heart, the transport of oxygen and to many other biological processes up to the point that we cannot even imagine a life without metals. In this book, the papers published in the Special Issue “The Role of Metal Ions in Biology, Biochemistry and Medicine” are summarized, providing a picture of metal ion uses in biology, biochemistry and medicine, but also pointing out the toxicity impacts on plants, animals, humans and the environment.

Research & information: general --- aluminium --- chlorophyll fluorescence --- durum wheat --- excitation pressure --- non-photochemical quenching --- photosynthesis --- photoprotection --- photoinhibition --- reactive oxygen species --- triticale --- Cd toxicity --- detoxification mechanism --- photochemical quenching --- photosynthetic heterogeneity --- photoprotective mechanism --- phytoremediation --- plastoquinone pool --- redox state --- spatiotemporal variation --- mercury --- biosorption --- dead cells --- Lysinibacillus sphaericus --- dithizone --- GF-AAS --- EDS-SEM --- adaptive response --- hormetic response --- hydrogen peroxide --- marine angiosperms --- reactive oxygen species (ROS) --- zinc oxide nanoparticles --- titanium dioxide --- nanoparticles --- solubility --- toxicity --- skin --- safety --- bimetallic nanoparticles --- mature leaves --- spatiotemporal heterogeneity --- young leaves --- osteoblasts --- corrosion --- ions --- particles --- osteolysis --- inflammation --- bioimaging --- clary sage --- effective quantum yield (ΦPSΙΙ) --- non-photochemical quenching (NPQ) --- photochemical quenching (qp) --- singlet oxygen (1O2) --- aseptic loosening --- metal ions --- monocytes --- macrophages --- 5-caffeoylquinic acid --- chlorogenic acid --- zinc --- plant phenolic compounds --- oxidative stress --- aluminium --- chlorophyll fluorescence --- durum wheat --- excitation pressure --- non-photochemical quenching --- photosynthesis --- photoprotection --- photoinhibition --- reactive oxygen species --- triticale --- Cd toxicity --- detoxification mechanism --- photochemical quenching --- photosynthetic heterogeneity --- photoprotective mechanism --- phytoremediation --- plastoquinone pool --- redox state --- spatiotemporal variation --- mercury --- biosorption --- dead cells --- Lysinibacillus sphaericus --- dithizone --- GF-AAS --- EDS-SEM --- adaptive response --- hormetic response --- hydrogen peroxide --- marine angiosperms --- reactive oxygen species (ROS) --- zinc oxide nanoparticles --- titanium dioxide --- nanoparticles --- solubility --- toxicity --- skin --- safety --- bimetallic nanoparticles --- mature leaves --- spatiotemporal heterogeneity --- young leaves --- osteoblasts --- corrosion --- ions --- particles --- osteolysis --- inflammation --- bioimaging --- clary sage --- effective quantum yield (ΦPSΙΙ) --- non-photochemical quenching (NPQ) --- photochemical quenching (qp) --- singlet oxygen (1O2) --- aseptic loosening --- metal ions --- monocytes --- macrophages --- 5-caffeoylquinic acid --- chlorogenic acid --- zinc --- plant phenolic compounds --- oxidative stress