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2022 (5)

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Book
Recent Advances in Antibody Therapeutics
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Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Since first receiving approval in 1986, antibody-based therapeutics have been the most successful modality for the treatment of various diseases. This Special Issue of IJMS, “Recent Advances in Antibody Therapeutics”, presents leading-edge articles and reviews for discovery, development, and clinical applications of therapeutic antibodies, covering antibody drug conjugates (ADCs), GPCR-targeting antibodies, a functional antibody screening, bioassay of bispecific antibodies, antibody applications for cardiovascular diseases, antibody delivery to CNS, etc. The excellent studies in this Special Issue would valuable insight for scientists and clinicians in the field of therapeutic antibodies

Keywords

Research & information: general --- Chemistry --- interleukin 33 --- ST2 receptor --- scFv --- C2_2E12 --- bladder cancer --- antibodies --- immune checkpoint inhibitors --- antibody-drug conjugates --- sacituzumab govitecan --- enfortumab vedotin --- erdafitinib --- cost-effectiveness --- G protein-coupled receptor --- membrane protein --- antigen --- therapeutic antibody --- anti-angiogenesis --- delta-like ligand --- irinotecan --- paclitaxel --- VEGF --- SARS-CoV-2 --- spike protein --- receptor-binding domain --- phage display --- monoclonal antibody --- cytomegalovirus --- peptide/major histocompatibility complex class I complex --- T-cell-receptor-like antibody --- affinity maturation --- yeast surface display --- combinatorial antibody library --- agonist antibody --- cell fate --- bispecific antibodies --- bioassays --- mechanisms of action --- binding assays --- potency assays --- atherosclerosis --- inflammation --- antibody therapy --- blood–brain barrier --- antibody --- pharmacokinetics --- disposition --- biochemical and physicochemical properties --- Fc binding --- receptor-mediated transcytosis --- brain shuttle --- molecular Trojan horse --- transferrin --- anti-cancer antibody --- antibody engineering --- biophysical properties --- computational methods --- research cell bank --- antibody therapeutics --- recombinant antibodies --- intracellular antibodies --- single-chain antibody fragment --- nanobody --- Human papillomaviruses --- HPV oncoproteins --- HPV-associated cancer --- HPV cancer therapy --- asthma --- refractory asthma --- biomarker --- n/a --- blood-brain barrier


Book
Recent Advances in Antibody Therapeutics
Author:
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Since first receiving approval in 1986, antibody-based therapeutics have been the most successful modality for the treatment of various diseases. This Special Issue of IJMS, “Recent Advances in Antibody Therapeutics”, presents leading-edge articles and reviews for discovery, development, and clinical applications of therapeutic antibodies, covering antibody drug conjugates (ADCs), GPCR-targeting antibodies, a functional antibody screening, bioassay of bispecific antibodies, antibody applications for cardiovascular diseases, antibody delivery to CNS, etc. The excellent studies in this Special Issue would valuable insight for scientists and clinicians in the field of therapeutic antibodies

Keywords

interleukin 33 --- ST2 receptor --- scFv --- C2_2E12 --- bladder cancer --- antibodies --- immune checkpoint inhibitors --- antibody-drug conjugates --- sacituzumab govitecan --- enfortumab vedotin --- erdafitinib --- cost-effectiveness --- G protein-coupled receptor --- membrane protein --- antigen --- therapeutic antibody --- anti-angiogenesis --- delta-like ligand --- irinotecan --- paclitaxel --- VEGF --- SARS-CoV-2 --- spike protein --- receptor-binding domain --- phage display --- monoclonal antibody --- cytomegalovirus --- peptide/major histocompatibility complex class I complex --- T-cell-receptor-like antibody --- affinity maturation --- yeast surface display --- combinatorial antibody library --- agonist antibody --- cell fate --- bispecific antibodies --- bioassays --- mechanisms of action --- binding assays --- potency assays --- atherosclerosis --- inflammation --- antibody therapy --- blood–brain barrier --- antibody --- pharmacokinetics --- disposition --- biochemical and physicochemical properties --- Fc binding --- receptor-mediated transcytosis --- brain shuttle --- molecular Trojan horse --- transferrin --- anti-cancer antibody --- antibody engineering --- biophysical properties --- computational methods --- research cell bank --- antibody therapeutics --- recombinant antibodies --- intracellular antibodies --- single-chain antibody fragment --- nanobody --- Human papillomaviruses --- HPV oncoproteins --- HPV-associated cancer --- HPV cancer therapy --- asthma --- refractory asthma --- biomarker --- n/a --- blood-brain barrier


Book
Biosensors for Diagnosis and Monitoring
Author:
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Biosensor technologies have received a great amount of interest in recent decades, and this has especially been the case in recent years due to the health alert caused by the COVID-19 pandemic. The sensor platform market has grown in recent decades, and the COVID-19 outbreak has led to an increase in the demand for home diagnostics and point-of-care systems. With the evolution of biosensor technology towards portable platforms with a lower cost on-site analysis and a rapid selective and sensitive response, a larger market has opened up for this technology. The evolution of biosensor systems has the opportunity to change classic analysis towards real-time and in situ detection systems, with platforms such as point-of-care and wearables as well as implantable sensors to decentralize chemical and biological analysis, thus reducing industrial and medical costs. This book is dedicated to all the research related to biosensor technologies. Reviews, perspective articles, and research articles in different biosensing areas such as wearable sensors, point-of-care platforms, and pathogen detection for biomedical applications as well as environmental monitoring will introduce the reader to these relevant topics. This book is aimed at scientists and professionals working in the field of biosensors and also provides essential knowledge for students who want to enter the field.

Keywords

Research & information: general --- Chemistry --- Analytical chemistry --- biosensors --- interdigitated electrodes --- impedance spectroscopy --- blood analysis --- whole-cell biosensor --- yeast surface display --- cholesterol oxidase --- glucose dehydrogenase --- electrochemical detection --- fiber optic sensor --- vital signs --- biosensor --- human body --- body temperature --- heart rate --- respiratory rate --- blood pressure --- torso scanning --- antennas --- processing algorithms --- electromagnetic imaging --- polymerase chain reaction --- COVID-19 --- electrochemical --- digital PCR --- point-of-care --- electroanalysis --- indigo dyes --- fast identification --- fingerprints --- differential pulse voltammetry --- cystatin C --- molecularly imprinted polymer --- electrochemical biosensor --- polypyrene --- multiwall carbon nanotubes --- acute kidney injury --- biomonitoring --- personalized healthcare --- sweat --- rolling circle amplification --- environmental monitoring --- heavy metals --- organic molecules --- microorganisms --- biorecognition --- diagnosis --- pathogens --- aptamers --- antibodies --- peptides --- enzymes --- DNAzymes --- peptide nucleic acids --- blood glucose monitoring --- diabetes --- non-invasive sensor --- PDMS --- vascular phantom --- glucometer --- RF sensor --- CD4+ T helper cells --- microfluidic chip --- microbeads --- wide-field optical system --- ImageJ --- graphene --- reduced graphene oxide --- electrochemistry --- electrochemical impedance spectroscopy --- DNA biosensor --- diazonium chemistry --- screen-printed electrodes --- DNA hybridization --- VOCs --- environmental --- packaging --- diagnostic --- pollution --- colorectal cancer --- KRAS --- lateral flow assay --- dipstick --- gold nanoparticles --- diagnostics --- multiplex --- point-of-care diagnostics --- REASSURED --- biosensors --- interdigitated electrodes --- impedance spectroscopy --- blood analysis --- whole-cell biosensor --- yeast surface display --- cholesterol oxidase --- glucose dehydrogenase --- electrochemical detection --- fiber optic sensor --- vital signs --- biosensor --- human body --- body temperature --- heart rate --- respiratory rate --- blood pressure --- torso scanning --- antennas --- processing algorithms --- electromagnetic imaging --- polymerase chain reaction --- COVID-19 --- electrochemical --- digital PCR --- point-of-care --- electroanalysis --- indigo dyes --- fast identification --- fingerprints --- differential pulse voltammetry --- cystatin C --- molecularly imprinted polymer --- electrochemical biosensor --- polypyrene --- multiwall carbon nanotubes --- acute kidney injury --- biomonitoring --- personalized healthcare --- sweat --- rolling circle amplification --- environmental monitoring --- heavy metals --- organic molecules --- microorganisms --- biorecognition --- diagnosis --- pathogens --- aptamers --- antibodies --- peptides --- enzymes --- DNAzymes --- peptide nucleic acids --- blood glucose monitoring --- diabetes --- non-invasive sensor --- PDMS --- vascular phantom --- glucometer --- RF sensor --- CD4+ T helper cells --- microfluidic chip --- microbeads --- wide-field optical system --- ImageJ --- graphene --- reduced graphene oxide --- electrochemistry --- electrochemical impedance spectroscopy --- DNA biosensor --- diazonium chemistry --- screen-printed electrodes --- DNA hybridization --- VOCs --- environmental --- packaging --- diagnostic --- pollution --- colorectal cancer --- KRAS --- lateral flow assay --- dipstick --- gold nanoparticles --- diagnostics --- multiplex --- point-of-care diagnostics --- REASSURED


Book
Recent Advances in Antibody Therapeutics
Author:
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

Since first receiving approval in 1986, antibody-based therapeutics have been the most successful modality for the treatment of various diseases. This Special Issue of IJMS, “Recent Advances in Antibody Therapeutics”, presents leading-edge articles and reviews for discovery, development, and clinical applications of therapeutic antibodies, covering antibody drug conjugates (ADCs), GPCR-targeting antibodies, a functional antibody screening, bioassay of bispecific antibodies, antibody applications for cardiovascular diseases, antibody delivery to CNS, etc. The excellent studies in this Special Issue would valuable insight for scientists and clinicians in the field of therapeutic antibodies

Keywords

Research & information: general --- Chemistry --- interleukin 33 --- ST2 receptor --- scFv --- C2_2E12 --- bladder cancer --- antibodies --- immune checkpoint inhibitors --- antibody-drug conjugates --- sacituzumab govitecan --- enfortumab vedotin --- erdafitinib --- cost-effectiveness --- G protein-coupled receptor --- membrane protein --- antigen --- therapeutic antibody --- anti-angiogenesis --- delta-like ligand --- irinotecan --- paclitaxel --- VEGF --- SARS-CoV-2 --- spike protein --- receptor-binding domain --- phage display --- monoclonal antibody --- cytomegalovirus --- peptide/major histocompatibility complex class I complex --- T-cell-receptor-like antibody --- affinity maturation --- yeast surface display --- combinatorial antibody library --- agonist antibody --- cell fate --- bispecific antibodies --- bioassays --- mechanisms of action --- binding assays --- potency assays --- atherosclerosis --- inflammation --- antibody therapy --- blood-brain barrier --- antibody --- pharmacokinetics --- disposition --- biochemical and physicochemical properties --- Fc binding --- receptor-mediated transcytosis --- brain shuttle --- molecular Trojan horse --- transferrin --- anti-cancer antibody --- antibody engineering --- biophysical properties --- computational methods --- research cell bank --- antibody therapeutics --- recombinant antibodies --- intracellular antibodies --- single-chain antibody fragment --- nanobody --- Human papillomaviruses --- HPV oncoproteins --- HPV-associated cancer --- HPV cancer therapy --- asthma --- refractory asthma --- biomarker --- interleukin 33 --- ST2 receptor --- scFv --- C2_2E12 --- bladder cancer --- antibodies --- immune checkpoint inhibitors --- antibody-drug conjugates --- sacituzumab govitecan --- enfortumab vedotin --- erdafitinib --- cost-effectiveness --- G protein-coupled receptor --- membrane protein --- antigen --- therapeutic antibody --- anti-angiogenesis --- delta-like ligand --- irinotecan --- paclitaxel --- VEGF --- SARS-CoV-2 --- spike protein --- receptor-binding domain --- phage display --- monoclonal antibody --- cytomegalovirus --- peptide/major histocompatibility complex class I complex --- T-cell-receptor-like antibody --- affinity maturation --- yeast surface display --- combinatorial antibody library --- agonist antibody --- cell fate --- bispecific antibodies --- bioassays --- mechanisms of action --- binding assays --- potency assays --- atherosclerosis --- inflammation --- antibody therapy --- blood-brain barrier --- antibody --- pharmacokinetics --- disposition --- biochemical and physicochemical properties --- Fc binding --- receptor-mediated transcytosis --- brain shuttle --- molecular Trojan horse --- transferrin --- anti-cancer antibody --- antibody engineering --- biophysical properties --- computational methods --- research cell bank --- antibody therapeutics --- recombinant antibodies --- intracellular antibodies --- single-chain antibody fragment --- nanobody --- Human papillomaviruses --- HPV oncoproteins --- HPV-associated cancer --- HPV cancer therapy --- asthma --- refractory asthma --- biomarker


Book
Biosensors for Diagnosis and Monitoring
Author:
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

Biosensor technologies have received a great amount of interest in recent decades, and this has especially been the case in recent years due to the health alert caused by the COVID-19 pandemic. The sensor platform market has grown in recent decades, and the COVID-19 outbreak has led to an increase in the demand for home diagnostics and point-of-care systems. With the evolution of biosensor technology towards portable platforms with a lower cost on-site analysis and a rapid selective and sensitive response, a larger market has opened up for this technology. The evolution of biosensor systems has the opportunity to change classic analysis towards real-time and in situ detection systems, with platforms such as point-of-care and wearables as well as implantable sensors to decentralize chemical and biological analysis, thus reducing industrial and medical costs. This book is dedicated to all the research related to biosensor technologies. Reviews, perspective articles, and research articles in different biosensing areas such as wearable sensors, point-of-care platforms, and pathogen detection for biomedical applications as well as environmental monitoring will introduce the reader to these relevant topics. This book is aimed at scientists and professionals working in the field of biosensors and also provides essential knowledge for students who want to enter the field.

Keywords

biosensors --- interdigitated electrodes --- impedance spectroscopy --- blood analysis --- whole-cell biosensor --- yeast surface display --- cholesterol oxidase --- glucose dehydrogenase --- electrochemical detection --- fiber optic sensor --- vital signs --- biosensor --- human body --- body temperature --- heart rate --- respiratory rate --- blood pressure --- torso scanning --- antennas --- processing algorithms --- electromagnetic imaging --- polymerase chain reaction --- COVID-19 --- electrochemical --- digital PCR --- point-of-care --- electroanalysis --- indigo dyes --- fast identification --- fingerprints --- differential pulse voltammetry --- cystatin C --- molecularly imprinted polymer --- electrochemical biosensor --- polypyrene --- multiwall carbon nanotubes --- acute kidney injury --- biomonitoring --- personalized healthcare --- sweat --- rolling circle amplification --- environmental monitoring --- heavy metals --- organic molecules --- microorganisms --- biorecognition --- diagnosis --- pathogens --- aptamers --- antibodies --- peptides --- enzymes --- DNAzymes --- peptide nucleic acids --- blood glucose monitoring --- diabetes --- non-invasive sensor --- PDMS --- vascular phantom --- glucometer --- RF sensor --- CD4+ T helper cells --- microfluidic chip --- microbeads --- wide-field optical system --- ImageJ --- graphene --- reduced graphene oxide --- electrochemistry --- electrochemical impedance spectroscopy --- DNA biosensor --- diazonium chemistry --- screen-printed electrodes --- DNA hybridization --- VOCs --- environmental --- packaging --- diagnostic --- pollution --- colorectal cancer --- KRAS --- lateral flow assay --- dipstick --- gold nanoparticles --- diagnostics --- multiplex --- point-of-care diagnostics --- REASSURED

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