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Book
New Mechanisms of Action of Natural Antioxidants in Health and Disease
Authors: ---
Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

This book contributes to increasing the knowledge on the mechanisms of action of natural antioxidants, evidencing their pleiotropic role in the prevention and/or counteraction of degenerative diseases, and promoting their application in the functional food and cosmetic fields.


Book
Centenarians-A Model to Study the Molecular Basis of Lifespan and Healthspan
Authors: ---
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

People around the world are living longer. For the first time in history, most humans will live to be sixty and beyond. By 2050, the world's population aged 60 and over will reach a total of 2 billion, up from 900 million in 2015. Today, 125 million people are 80 years of age or older. By 2050, there will be 434 million people in this age group worldwide. In addition, the pace of aging of the world population is also increasing. However, there is not enough evidence to show that older people have better health than their parents. While rates of severe disability have declined over the past 30 years (but only in high-income countries), there have been no significant changes in mild to moderate disability over the same period of time. Indeed, the increase in the duration of life (lifespan) does not coincide with the increase in the duration of health (healthspan), that is, the period of life free from serious chronic diseases and disabilities. Therefore, the identification of the factors that predispose to a long and healthy life, as discussed in the papers of this book, is of enormous interest for translational medicine.


Book
New Mechanisms of Action of Natural Antioxidants in Health and Disease
Authors: ---
Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

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Bookmark

Abstract

This book contributes to increasing the knowledge on the mechanisms of action of natural antioxidants, evidencing their pleiotropic role in the prevention and/or counteraction of degenerative diseases, and promoting their application in the functional food and cosmetic fields.


Book
New Mechanisms of Action of Natural Antioxidants in Health and Disease
Authors: ---
Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Bookmark

Abstract

This book contributes to increasing the knowledge on the mechanisms of action of natural antioxidants, evidencing their pleiotropic role in the prevention and/or counteraction of degenerative diseases, and promoting their application in the functional food and cosmetic fields.

Keywords

Humanities --- Social interaction --- CNS --- fava beans --- glucose --- fructose --- oxidative stress --- vitagenes --- neurodegeneration --- SH-SY5Y cell line --- 3D cultures --- phytochemicals --- antioxidants --- cyanidin-3-glucoside --- phenolic metabolites --- gut microbiota --- signaling pathways --- intestinal injury --- proliferation --- migration --- vascular smooth muscle cells --- atherosclerosis --- tumor necrosis factor-alpha --- Hibiscus leaf polyphenols --- Rosmarinus officinalis --- essential oil --- scopolamine --- anxiety --- memory --- Ectoine --- keratinocytes --- melanogenesis --- tyrosinase --- α-MSH --- Nrf2 --- bioactive peptides --- Keap1/Nrf2 pathway --- natural antioxidants --- FPP® --- nutraceutical supplementation --- C57BL/6J --- anti-aging effect --- antioxidant effect --- telomeres --- telomerase --- SOD-1 --- GSH --- natural antioxidant --- seaweed --- algae --- Fucus vesiculosus --- CNS --- fava beans --- glucose --- fructose --- oxidative stress --- vitagenes --- neurodegeneration --- SH-SY5Y cell line --- 3D cultures --- phytochemicals --- antioxidants --- cyanidin-3-glucoside --- phenolic metabolites --- gut microbiota --- signaling pathways --- intestinal injury --- proliferation --- migration --- vascular smooth muscle cells --- atherosclerosis --- tumor necrosis factor-alpha --- Hibiscus leaf polyphenols --- Rosmarinus officinalis --- essential oil --- scopolamine --- anxiety --- memory --- Ectoine --- keratinocytes --- melanogenesis --- tyrosinase --- α-MSH --- Nrf2 --- bioactive peptides --- Keap1/Nrf2 pathway --- natural antioxidants --- FPP® --- nutraceutical supplementation --- C57BL/6J --- anti-aging effect --- antioxidant effect --- telomeres --- telomerase --- SOD-1 --- GSH --- natural antioxidant --- seaweed --- algae --- Fucus vesiculosus


Book
Centenarians-A Model to Study the Molecular Basis of Lifespan and Healthspan
Authors: ---
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

People around the world are living longer. For the first time in history, most humans will live to be sixty and beyond. By 2050, the world's population aged 60 and over will reach a total of 2 billion, up from 900 million in 2015. Today, 125 million people are 80 years of age or older. By 2050, there will be 434 million people in this age group worldwide. In addition, the pace of aging of the world population is also increasing. However, there is not enough evidence to show that older people have better health than their parents. While rates of severe disability have declined over the past 30 years (but only in high-income countries), there have been no significant changes in mild to moderate disability over the same period of time. Indeed, the increase in the duration of life (lifespan) does not coincide with the increase in the duration of health (healthspan), that is, the period of life free from serious chronic diseases and disabilities. Therefore, the identification of the factors that predispose to a long and healthy life, as discussed in the papers of this book, is of enormous interest for translational medicine.

Keywords

Research & information: general --- Biology, life sciences --- aging --- alternative therapy --- composition of royal jelly --- dietary interventions --- healthspan --- lifespan --- longevity --- royal jelly --- IGF-1 --- oxidative stress --- ageing --- nematode --- immunosenescence --- probiotic bacteria --- pathogen protection --- food allergy --- elderly --- hypersensitivity --- gut --- allergy --- inflammation --- redoxomics --- glutathione --- meniere's disease --- neurodegenerative diseases --- healthy aging --- DNA methylation --- epigenetic clocks --- telomere length --- centenarians --- exosomes --- serum --- functional enrichment analysis --- ingenuity pathway analysis --- miRNA-mRNA networks --- aging-related disease --- Di (2-Ethylhexyl) pthalate --- Hericium erinaceus --- vitagenes --- apoptosis --- mitochondrial respiratory complexes --- C. elegans --- polyphenols --- olive oil --- Parkinson's disease --- β-Dystroglycan --- cellular senescence --- lamin B1 --- DNA-damage response --- defective mitosis --- aging --- alternative therapy --- composition of royal jelly --- dietary interventions --- healthspan --- lifespan --- longevity --- royal jelly --- IGF-1 --- oxidative stress --- ageing --- nematode --- immunosenescence --- probiotic bacteria --- pathogen protection --- food allergy --- elderly --- hypersensitivity --- gut --- allergy --- inflammation --- redoxomics --- glutathione --- meniere's disease --- neurodegenerative diseases --- healthy aging --- DNA methylation --- epigenetic clocks --- telomere length --- centenarians --- exosomes --- serum --- functional enrichment analysis --- ingenuity pathway analysis --- miRNA-mRNA networks --- aging-related disease --- Di (2-Ethylhexyl) pthalate --- Hericium erinaceus --- vitagenes --- apoptosis --- mitochondrial respiratory complexes --- C. elegans --- polyphenols --- olive oil --- Parkinson's disease --- β-Dystroglycan --- cellular senescence --- lamin B1 --- DNA-damage response --- defective mitosis

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