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Book
Multimodality Treatments in Metastatic Gastric Cancer
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Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Gastric cancer represents one of the most frequent and lethal tumors worldwide today, finding itself in the fifth place in incidence and the third in mortality. Surgery remains the only curative treatment for localized tumors, but only 20% of patients are suitable for surgery due to the lack of specific symptoms and the late diagnosis, especially in Western countries. Additionally, even in patients who receive curative treatment, rates of locoregional relapse and distant metastasis remain high. Palliative chemotherapy is the principal treatment in cases of metastatic disease even if the prognosis of patients receiving chemotherapy is still poor. Therefore, a multidisciplinary evaluation is important in order to improve the efficacy of active treatments. In this context, there is an unmet need for a better understanding of genetic alterations and prognostic and predictive factors in order to choose the best tailored therapy for each patient. The aim of this Special Issue is to focus on the results and problems of multimodality treatment in metastatic gastric cancer, the search for prognostic and predictive factors, and the evaluation of novel strategies for individualized treatment. We are inviting relevant original research, systematic reviews, meta-analyses, and short communications covering the above-mentioned topics.


Book
Multimodality Treatments in Metastatic Gastric Cancer
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Gastric cancer represents one of the most frequent and lethal tumors worldwide today, finding itself in the fifth place in incidence and the third in mortality. Surgery remains the only curative treatment for localized tumors, but only 20% of patients are suitable for surgery due to the lack of specific symptoms and the late diagnosis, especially in Western countries. Additionally, even in patients who receive curative treatment, rates of locoregional relapse and distant metastasis remain high. Palliative chemotherapy is the principal treatment in cases of metastatic disease even if the prognosis of patients receiving chemotherapy is still poor. Therefore, a multidisciplinary evaluation is important in order to improve the efficacy of active treatments. In this context, there is an unmet need for a better understanding of genetic alterations and prognostic and predictive factors in order to choose the best tailored therapy for each patient. The aim of this Special Issue is to focus on the results and problems of multimodality treatment in metastatic gastric cancer, the search for prognostic and predictive factors, and the evaluation of novel strategies for individualized treatment. We are inviting relevant original research, systematic reviews, meta-analyses, and short communications covering the above-mentioned topics.

Keywords

Medicine --- advanced gastric cancer --- precision medicine --- new drug development --- gastro-oesophageal cancer --- mutational concordance --- exome sequencing --- formalin fixed paraffin embedded --- biomarkers --- gastric cancer --- metastatic --- body composition --- sarcopenia --- visceral fat area --- subcutaneous fat area --- outcome --- toxicity --- liver metastasis --- conversion surgery --- hepatectomy --- stage iv gastric cancer --- immune checkpoint inhibitors --- Epstein Barr Virus --- tumor mutational burden --- microsatellite instability --- predictive biomarkers --- CAR T cell therapy --- vaccines --- nutritional status --- metastatic gastric cancer --- target therapy --- bone flare --- stage IV --- treatment --- RANK-L --- liquid biopsy --- circulating tumor cell --- cfDNA --- ctDNA --- epithelial-mesenchymal transition --- resistance to treatment --- HER2-inhibition --- VEGFR-inhibition --- immunotherapy --- response monitoring --- advanced gastric cancer --- precision medicine --- new drug development --- gastro-oesophageal cancer --- mutational concordance --- exome sequencing --- formalin fixed paraffin embedded --- biomarkers --- gastric cancer --- metastatic --- body composition --- sarcopenia --- visceral fat area --- subcutaneous fat area --- outcome --- toxicity --- liver metastasis --- conversion surgery --- hepatectomy --- stage iv gastric cancer --- immune checkpoint inhibitors --- Epstein Barr Virus --- tumor mutational burden --- microsatellite instability --- predictive biomarkers --- CAR T cell therapy --- vaccines --- nutritional status --- metastatic gastric cancer --- target therapy --- bone flare --- stage IV --- treatment --- RANK-L --- liquid biopsy --- circulating tumor cell --- cfDNA --- ctDNA --- epithelial-mesenchymal transition --- resistance to treatment --- HER2-inhibition --- VEGFR-inhibition --- immunotherapy --- response monitoring


Book
Fitness Assessment, Athlete’s Monitoring Cycle and Training Interventions in Team Sports
Authors: ---
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Team sports training are progressively growing, and thus challenging strength and conditioning coaches and head coaches. As part of a well-prepared training strategy, it is important to establish a functional relationship among fitness assessment, load, and well-being monitoring and readiness analysis to identify the consequences of training stimulus for players. Each of these topics has already been isolated in research; however, it is important to bridge the gap between them and establish a greater and more comprehensive approach among fitness adaptations, training monitoring, and specific interventions performed. This may help us to achieve a clearer view of the big picture in terms of the consequences for players, such as, considering their exposure to successful biological adaptations or less successful cases, including illness or injuries. As it is clear that more research should be performed on the relationship among these dimensions and topics, the aim of the Special Issue on "Fitness Assessment, Athlete’s Monitoring Cycle and Training Interventions in Team Sports" was to publish high-quality original investigations, systematic reviews, and meta-analysis in the research field of team sports. We have published 22 articles that cover the topics of performance assessment and relationships between fitness measures; training load monitoring, well-being, and readiness in team sports;training interventions; complementary strategies for performance (e.g., nutrition, supplementation, psychology, injury preventions, and recovery); and determinants of illness and injuries in players.

Keywords

Humanities --- Social interaction --- football --- load monitoring --- situational variables --- GPS --- sports science --- youth handball players′ characteristics --- RSA test --- anaerobic performance --- playing position characteristics --- asymmetry --- soccer --- strength --- youth --- muscles --- acceleration --- deceleration --- in-season --- non-starters --- pre-season --- starters --- training monotony --- training strain --- ball throwing --- hand size --- arm span --- motor performance --- stretch-shortening cycle --- additional weight --- ability-to-change-direction --- speed --- balance --- repeated change of direction --- autonomic nervous system --- cardiac autonomic --- vagal tone --- adolescents --- training load --- match analysis --- team sports performance --- exercise training --- velocity --- team sport performance --- injury risk screening --- athletes assessment --- landing error score system --- counter movement jump --- team sports --- statistical analysis --- correlation --- monitoring --- RPE --- heart rate --- beach handball --- youth athletes --- training interventions --- fitness assessment --- strength and conditioning --- female --- association football --- performance --- external load --- isoinertial training --- strength training --- vertical jump --- change of direction ability --- high-speed running --- match --- match result --- performance analysis --- technology --- inertial measurement units --- neuromuscular --- repeated jump --- max speed --- Loughborough Intermittent Shuttle Test --- muscle soreness --- maximal isometric contraction strength --- countermovement jump --- Yo-Yo Intermittent Recovery Test level 1 --- soccer constraints --- small-sided games --- athletic performance --- sports training --- internal load --- body symmetry --- ski jumpers --- segmental phase angle --- visceral fat area --- BIA --- winter sports --- nutritional status --- soccer training --- s-RPE --- Hooper index --- match day --- match location --- physiology --- time motion --- notational analysis --- football --- load monitoring --- situational variables --- GPS --- sports science --- youth handball players′ characteristics --- RSA test --- anaerobic performance --- playing position characteristics --- asymmetry --- soccer --- strength --- youth --- muscles --- acceleration --- deceleration --- in-season --- non-starters --- pre-season --- starters --- training monotony --- training strain --- ball throwing --- hand size --- arm span --- motor performance --- stretch-shortening cycle --- additional weight --- ability-to-change-direction --- speed --- balance --- repeated change of direction --- autonomic nervous system --- cardiac autonomic --- vagal tone --- adolescents --- training load --- match analysis --- team sports performance --- exercise training --- velocity --- team sport performance --- injury risk screening --- athletes assessment --- landing error score system --- counter movement jump --- team sports --- statistical analysis --- correlation --- monitoring --- RPE --- heart rate --- beach handball --- youth athletes --- training interventions --- fitness assessment --- strength and conditioning --- female --- association football --- performance --- external load --- isoinertial training --- strength training --- vertical jump --- change of direction ability --- high-speed running --- match --- match result --- performance analysis --- technology --- inertial measurement units --- neuromuscular --- repeated jump --- max speed --- Loughborough Intermittent Shuttle Test --- muscle soreness --- maximal isometric contraction strength --- countermovement jump --- Yo-Yo Intermittent Recovery Test level 1 --- soccer constraints --- small-sided games --- athletic performance --- sports training --- internal load --- body symmetry --- ski jumpers --- segmental phase angle --- visceral fat area --- BIA --- winter sports --- nutritional status --- soccer training --- s-RPE --- Hooper index --- match day --- match location --- physiology --- time motion --- notational analysis


Book
Fitness Assessment, Athlete’s Monitoring Cycle and Training Interventions in Team Sports
Authors: ---
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

Team sports training are progressively growing, and thus challenging strength and conditioning coaches and head coaches. As part of a well-prepared training strategy, it is important to establish a functional relationship among fitness assessment, load, and well-being monitoring and readiness analysis to identify the consequences of training stimulus for players. Each of these topics has already been isolated in research; however, it is important to bridge the gap between them and establish a greater and more comprehensive approach among fitness adaptations, training monitoring, and specific interventions performed. This may help us to achieve a clearer view of the big picture in terms of the consequences for players, such as, considering their exposure to successful biological adaptations or less successful cases, including illness or injuries. As it is clear that more research should be performed on the relationship among these dimensions and topics, the aim of the Special Issue on "Fitness Assessment, Athlete’s Monitoring Cycle and Training Interventions in Team Sports" was to publish high-quality original investigations, systematic reviews, and meta-analysis in the research field of team sports. We have published 22 articles that cover the topics of performance assessment and relationships between fitness measures; training load monitoring, well-being, and readiness in team sports;training interventions; complementary strategies for performance (e.g., nutrition, supplementation, psychology, injury preventions, and recovery); and determinants of illness and injuries in players.

Keywords

Humanities --- Social interaction --- football --- load monitoring --- situational variables --- GPS --- sports science --- youth handball players′ characteristics --- RSA test --- anaerobic performance --- playing position characteristics --- asymmetry --- soccer --- strength --- youth --- muscles --- acceleration --- deceleration --- in-season --- non-starters --- pre-season --- starters --- training monotony --- training strain --- ball throwing --- hand size --- arm span --- motor performance --- stretch-shortening cycle --- additional weight --- ability-to-change-direction --- speed --- balance --- repeated change of direction --- autonomic nervous system --- cardiac autonomic --- vagal tone --- adolescents --- training load --- match analysis --- team sports performance --- exercise training --- velocity --- team sport performance --- injury risk screening --- athletes assessment --- landing error score system --- counter movement jump --- team sports --- statistical analysis --- correlation --- monitoring --- RPE --- heart rate --- beach handball --- youth athletes --- training interventions --- fitness assessment --- strength and conditioning --- female --- association football --- performance --- external load --- isoinertial training --- strength training --- vertical jump --- change of direction ability --- high-speed running --- match --- match result --- performance analysis --- technology --- inertial measurement units --- neuromuscular --- repeated jump --- max speed --- Loughborough Intermittent Shuttle Test --- muscle soreness --- maximal isometric contraction strength --- countermovement jump --- Yo-Yo Intermittent Recovery Test level 1 --- soccer constraints --- small-sided games --- athletic performance --- sports training --- internal load --- body symmetry --- ski jumpers --- segmental phase angle --- visceral fat area --- BIA --- winter sports --- nutritional status --- soccer training --- s-RPE --- Hooper index --- match day --- match location --- physiology --- time motion --- notational analysis


Book
Fitness Assessment, Athlete’s Monitoring Cycle and Training Interventions in Team Sports
Authors: ---
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

Team sports training are progressively growing, and thus challenging strength and conditioning coaches and head coaches. As part of a well-prepared training strategy, it is important to establish a functional relationship among fitness assessment, load, and well-being monitoring and readiness analysis to identify the consequences of training stimulus for players. Each of these topics has already been isolated in research; however, it is important to bridge the gap between them and establish a greater and more comprehensive approach among fitness adaptations, training monitoring, and specific interventions performed. This may help us to achieve a clearer view of the big picture in terms of the consequences for players, such as, considering their exposure to successful biological adaptations or less successful cases, including illness or injuries. As it is clear that more research should be performed on the relationship among these dimensions and topics, the aim of the Special Issue on "Fitness Assessment, Athlete’s Monitoring Cycle and Training Interventions in Team Sports" was to publish high-quality original investigations, systematic reviews, and meta-analysis in the research field of team sports. We have published 22 articles that cover the topics of performance assessment and relationships between fitness measures; training load monitoring, well-being, and readiness in team sports;training interventions; complementary strategies for performance (e.g., nutrition, supplementation, psychology, injury preventions, and recovery); and determinants of illness and injuries in players.

Keywords

football --- load monitoring --- situational variables --- GPS --- sports science --- youth handball players′ characteristics --- RSA test --- anaerobic performance --- playing position characteristics --- asymmetry --- soccer --- strength --- youth --- muscles --- acceleration --- deceleration --- in-season --- non-starters --- pre-season --- starters --- training monotony --- training strain --- ball throwing --- hand size --- arm span --- motor performance --- stretch-shortening cycle --- additional weight --- ability-to-change-direction --- speed --- balance --- repeated change of direction --- autonomic nervous system --- cardiac autonomic --- vagal tone --- adolescents --- training load --- match analysis --- team sports performance --- exercise training --- velocity --- team sport performance --- injury risk screening --- athletes assessment --- landing error score system --- counter movement jump --- team sports --- statistical analysis --- correlation --- monitoring --- RPE --- heart rate --- beach handball --- youth athletes --- training interventions --- fitness assessment --- strength and conditioning --- female --- association football --- performance --- external load --- isoinertial training --- strength training --- vertical jump --- change of direction ability --- high-speed running --- match --- match result --- performance analysis --- technology --- inertial measurement units --- neuromuscular --- repeated jump --- max speed --- Loughborough Intermittent Shuttle Test --- muscle soreness --- maximal isometric contraction strength --- countermovement jump --- Yo-Yo Intermittent Recovery Test level 1 --- soccer constraints --- small-sided games --- athletic performance --- sports training --- internal load --- body symmetry --- ski jumpers --- segmental phase angle --- visceral fat area --- BIA --- winter sports --- nutritional status --- soccer training --- s-RPE --- Hooper index --- match day --- match location --- physiology --- time motion --- notational analysis

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