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Periodical
Prostaglandins, leukotrienes, and medicine.
ISSN: 18792847 Year: 1982 Publisher: Edinburgh ; New York : Churchill Livingstone


Book
Biocatalytic Synthesis of Bioactive Compounds
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Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Biocatalysis, the application of enzymes as catalysts for chemical synthesis, has become an increasingly valuable tool for the synthetic chemist. Enzymatic transformations carried out by enzymes or whole-cell catalysts are used for the production of a wide variety of compounds ranging from bulk to fine chemicals. The primary consideration for the incorporation of biotransformation in a synthetic sequence is regio- and stereocontrol that can be achieved with enzyme-catalyzed reactions. Biotransformations are thus becoming accepted as a method for generating optically pure compounds as well as for developing efficient routes to target compounds. This Special Issue aims to address the main applications of biocatalysts, isolated enzymes, and whole microorganisms in the synthesis of bioactive compounds and their precursors.


Book
Biocatalytic Synthesis of Bioactive Compounds
Author:
Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Biocatalysis, the application of enzymes as catalysts for chemical synthesis, has become an increasingly valuable tool for the synthetic chemist. Enzymatic transformations carried out by enzymes or whole-cell catalysts are used for the production of a wide variety of compounds ranging from bulk to fine chemicals. The primary consideration for the incorporation of biotransformation in a synthetic sequence is regio- and stereocontrol that can be achieved with enzyme-catalyzed reactions. Biotransformations are thus becoming accepted as a method for generating optically pure compounds as well as for developing efficient routes to target compounds. This Special Issue aims to address the main applications of biocatalysts, isolated enzymes, and whole microorganisms in the synthesis of bioactive compounds and their precursors.


Book
Biocatalytic Synthesis of Bioactive Compounds
Author:
Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Biocatalysis, the application of enzymes as catalysts for chemical synthesis, has become an increasingly valuable tool for the synthetic chemist. Enzymatic transformations carried out by enzymes or whole-cell catalysts are used for the production of a wide variety of compounds ranging from bulk to fine chemicals. The primary consideration for the incorporation of biotransformation in a synthetic sequence is regio- and stereocontrol that can be achieved with enzyme-catalyzed reactions. Biotransformations are thus becoming accepted as a method for generating optically pure compounds as well as for developing efficient routes to target compounds. This Special Issue aims to address the main applications of biocatalysts, isolated enzymes, and whole microorganisms in the synthesis of bioactive compounds and their precursors.

Keywords

Research & information: general --- Biology, life sciences --- 8-hydroxydaidzein --- stable --- soluble --- anti-inflammation --- amylosucrase --- Deinococcus geothermalis --- coumarin --- biotransformation --- filamentous fungi --- selective hydroxylation --- bromination --- chlorination --- pharmaceuticals --- active agent synthesis --- biocatalysis --- haloperoxidase --- halogenase --- glycosyltransferase --- Glycine max (L.) Merr. --- HPLC/MS --- isoflavone aglycone-rich extract --- isoflavone α-glucoside --- alkene cleavage --- aryl alkenes --- basidiomycota --- carotene degradation --- dye-decolorizing peroxidase (DyP) --- manganese --- Komagataella pfaffii --- Pleurotus sapidus --- monoterpenes --- limonene --- glycerol --- mevalonate pathway --- reaction engineering --- bioprocess --- biocatalyst --- two-liquid phase fermentation --- in situ product removal --- lipase --- unsaturated fatty acid --- oxidative cleavage --- oxidation --- adaptation --- UV/NTG mutagenesis --- psychrotrophs --- terpenes --- 8-hydroxydaidzein --- stable --- soluble --- anti-inflammation --- amylosucrase --- Deinococcus geothermalis --- coumarin --- biotransformation --- filamentous fungi --- selective hydroxylation --- bromination --- chlorination --- pharmaceuticals --- active agent synthesis --- biocatalysis --- haloperoxidase --- halogenase --- glycosyltransferase --- Glycine max (L.) Merr. --- HPLC/MS --- isoflavone aglycone-rich extract --- isoflavone α-glucoside --- alkene cleavage --- aryl alkenes --- basidiomycota --- carotene degradation --- dye-decolorizing peroxidase (DyP) --- manganese --- Komagataella pfaffii --- Pleurotus sapidus --- monoterpenes --- limonene --- glycerol --- mevalonate pathway --- reaction engineering --- bioprocess --- biocatalyst --- two-liquid phase fermentation --- in situ product removal --- lipase --- unsaturated fatty acid --- oxidative cleavage --- oxidation --- adaptation --- UV/NTG mutagenesis --- psychrotrophs --- terpenes

Polyunsaturated fatty acids in human nutrition : Nestlé nutrition workshop, held in Mexico City, November 27-30th, 1990
Authors: ---
ISBN: 088167933X Year: 1992 Volume: vol 28 Publisher: New York Raven Press

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Keywords

Fatty Acids, Unsaturated. --- Nutritional Physiological Phenomena. --- Unsaturated fatty acids in human nutrition --- -Nutrition --- Nutrition Phenomena --- Nutrition Physiological Concepts --- Nutrition Physiological Phenomenon --- Nutritional Phenomena --- Nutritional Physiological Phenomenon --- Nutritional Physiology --- Nutritional Physiology Concepts --- Nutritional Physiology Phenomenon --- Nutrition Physiological Phenomena --- Nutrition Physiology --- Nutritional Physiology Phenomena --- Concept, Nutrition Physiological --- Concept, Nutritional Physiology --- Concepts, Nutrition Physiological --- Concepts, Nutritional Physiology --- Nutrition Physiological Concept --- Nutritional Physiology Concept --- Phenomena, Nutrition --- Phenomena, Nutrition Physiological --- Phenomena, Nutritional --- Phenomena, Nutritional Physiological --- Phenomena, Nutritional Physiology --- Phenomenon, Nutrition Physiological --- Phenomenon, Nutritional Physiological --- Phenomenon, Nutritional Physiology --- Physiological Concept, Nutrition --- Physiological Concepts, Nutrition --- Physiological Phenomena, Nutrition --- Physiological Phenomena, Nutritional --- Physiological Phenomenon, Nutrition --- Physiological Phenomenon, Nutritional --- Physiology Concept, Nutritional --- Physiology Concepts, Nutritional --- Physiology Phenomena, Nutritional --- Physiology Phenomenon, Nutritional --- Physiology, Nutrition --- Physiology, Nutritional --- Food --- Nutritional Sciences --- Polyunsaturated Fatty Acids --- Fatty Acids, Polyunsaturated --- Acids, Polyunsaturated Fatty --- Acids, Unsaturated Fatty --- Unsaturated Fatty Acids --- Congresses --- Nutrition Process --- Nutritional Process --- Nutritional Processes --- Nutrition Processes --- Process, Nutrition --- Process, Nutritional --- Processes, Nutrition --- Processes, Nutritional --- Phototrophic Processes --- Autotrophic Processes --- Heterotrophic Processes --- Chemoautotrophic Growth --- -Congresses --- Fatty Acids, Unsaturated --- Nutritional Physiological Phenomena --- Nutrition --- Unsaturated fatty acids in human nutrition - Congresses. --- Polyunsaturated Fatty Acid --- Unsaturated Fatty Acid --- Acid, Polyunsaturated Fatty --- Acid, Unsaturated Fatty --- Fatty Acid, Polyunsaturated --- Fatty Acid, Unsaturated


Book
Transcriptome and Genome Analyses Applied to Aquaculture Research
Author:
ISBN: 3036559213 3036559221 Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Aquaculture is an important economic activity for food production all around the world that has experienced an exponential growth during the last few decades. However, several weaknesses and bottlenecks still need to be addressed in order to improve the aquaculture productive system. The recent fast development of the omics technologies has provided scientists with meaningful tools to elucidate the molecular basis of their research interests. This reprint compiles different works about the use of transcriptomics and genomics technologies in different aspects of the aquaculture research, such as immunity, stress response, development, sexual dimorphism, among others, in a variety of fish and shellfish, and even in turtles. Different transcriptome (mRNAs and non-coding RNAs (ncRNAs)), genome (Single Nucleotide Polymorphisms (SNPs)), and metatranscriptome analyses were conducted to unravel those different aspects of interest.

Keywords

Research & information: general --- Biology, life sciences --- Fisheries & related industries --- RNA-Seq --- lncRNAs --- Dicentrarchus labrax --- viral infection --- nodavirus --- immune response --- fish --- T lymphocytes --- infection --- malnutrition --- inflammation --- aquaculture --- histopathology --- immunohistochemistry --- enteromyxosis --- Philasterides dicentrarchi --- turbot --- transcriptomics --- Chinese mitten crab --- Eriocheir sinensis --- transportome --- transporters --- salinity --- osmoregulation --- transcriptome --- meta-analysis --- gills --- short pentraxins --- c-reactive protein --- zebrafish --- transcript expression --- antiviral --- SVCV --- rag1 mutants --- skin --- mucosal immunity --- hypoxia --- hypo-metabolic state --- growth --- swimming performance --- metabolic landmarks --- muscle transcriptome --- glycolysis --- lipid metabolism --- protein turnover --- gilthead sea bream --- hepatopancreas necrosis disease --- metatranscriptomics sequencing --- hepatopancreatic flora --- teleost --- B cells --- single cell transcriptomics --- immunoglobulins --- immune markers --- transcription factors --- long non-coding RNAs --- hepatic transcript expression --- salmon --- microarray --- omega-6/omega-3 ratio --- nutrigenomics --- fatty acids --- liver --- muscle --- Misgurnus anguillicaudatus --- sexual size dimorphism --- polyploid size dimorphism --- comparative transcriptome --- gene expression --- edible red sea urchin --- Loxechinus albus --- RNA-seq --- reference transcriptome --- Chinese soft-shelled turtle --- Aeromonas hydrophila --- hemorrhagic sepsis --- molecular immunopathogenesis --- tripartite motif proteins --- B30.2 domain --- antiviral immunity --- Ctenopharyngodon idella --- grass carp reovirus --- metamorphosis --- brain --- RNA --- sequencing --- intermuscular bone --- development --- Megalobrama amblycephala --- Oreochromis niloticus --- histological structure --- Atlantic salmon --- smoltification --- genome --- mRNAs --- miRNAs --- sox family genes --- Pelodiscus sinensis --- estradiol --- pseudo-female --- sex-related --- heterosis --- heterobeltiosis --- environment --- transgressive genes --- conserved miRNA --- high-throughput sequencing --- lumpfish --- novel miRNA --- RT-qPCR --- heat shock protein --- co-chaperon network --- salinity-alkalinity adaptation --- molecular evolution --- Lateolabrax maculatus --- genomics --- stress response --- HPI-axis --- neuroendocrine-immune interaction --- common carp --- poly-unsaturated fatty acid --- fatty acid elongase --- association study --- genomic selection --- bulked segregant analysis --- SNP --- association analysis --- joint effect --- seawater adaptation --- microRNAs --- small-RNA sequencing --- microarray transcriptome --- European seabass --- chronic inflammation --- opioid receptors --- immune status --- whole-transcriptome sequencing --- sex differentiation --- non-coding RNAs --- ceRNA --- red cusk-eel --- thermal stress --- liver transcriptome --- oxidative damage --- protein folding --- hepatic enzymes --- n/a


Book
Beyond boundaries of biomedicine
Authors: --- ---
ISBN: 141756427X 9781417564279 9401200882 Year: 2003 Publisher: Amsterdam New York, NY Rodopi

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Cultural forces shape much of medicine including psychiatry, and medicine shapes much of our culture. Medicine provides us with beneficial treatments of disease, but it also causes harm, increasingly so in the form of overmedication enhanced by the pharmaceutical industry. The book explores boundaries of medicine and psychiatry in a cultural setting by building bridges between unconnected literatures. Boundaries have to be redrawn since effects of the environment, biological, social and political, on health and disease are undervalued. Potential beneficial effects of diet therapies are a recurrent theme throughout the text, with particular emphasis on omega-3 fatty acids. Deficiencies of these acids in common diets may contribute to many chronic diseases and psychiatric disorders. The book uncovers limitations of evidence-based medicine, which fosters a restrictive view of health and disease. Case studies include: the biology of migraine; limitations of biological psychiatry; conventional versus alternative medicine; science, religion and near-death experiences.

Keywords

Medicine --- Clinical Medicine --- Evidence-Based Practice --- Behavioral Sciences --- Philosophy --- Pathologic Processes --- Dietary Fats, Unsaturated --- Fatty Acids, Unsaturated --- Health Occupations --- Fish Oils --- Investigative Techniques --- Humanities --- Behavioral Disciplines and Activities --- Fatty Acids --- Dietary Fats --- Oils --- Disciplines and Occupations --- Pathological Conditions, Signs and Symptoms --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Lipids --- Fats --- Diseases --- Psychiatry and Psychology --- Chemicals and Drugs --- Fatty Acids, Omega-3 --- Philosophy, Medical --- Evidence-Based Medicine --- Psychiatry --- Disease --- Methods --- Health & Biological Sciences --- Medical Ethics & Philosophy --- Fats, Dietary --- Dietary Fat --- Fat, Dietary --- Aliphatic Acids --- Aliphatic Acid --- Esterified Fatty Acid --- Fatty Acid --- Fatty Acids, Esterified --- Fatty Acids, Saturated --- Saturated Fatty Acid --- Acid, Aliphatic --- Acid, Esterified Fatty --- Acid, Saturated Fatty --- Esterified Fatty Acids --- Fatty Acid, Esterified --- Fatty Acid, Saturated --- Saturated Fatty Acids --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Fish Oil --- Fish Liver Oils --- Liver Oils, Fish --- Oil, Fish --- Oils, Fish --- Oils, Fish Liver --- Health Professions --- Health Occupation --- Health Profession --- Profession, Health --- Professions, Health --- Occupations --- Polyunsaturated Fatty Acids --- Fatty Acids, Polyunsaturated --- Polyunsaturated Fatty Acid --- Unsaturated Fatty Acid --- Acid, Polyunsaturated Fatty --- Acid, Unsaturated Fatty --- Acids, Polyunsaturated Fatty --- Acids, Unsaturated Fatty --- Fatty Acid, Polyunsaturated --- Fatty Acid, Unsaturated --- Unsaturated Fatty Acids --- Dietary Oils --- Unsaturated Dietary Fats --- Dietary Fat, Unsaturated --- Dietary Oil --- Fat, Unsaturated Dietary --- Fats, Unsaturated Dietary --- Oil, Dietary --- Oils, Dietary --- Unsaturated Dietary Fat --- Pathological Processes --- Processes, Pathologic --- Processes, Pathological --- Pharmacy Philosophy --- Philosophical Overview --- Hedonism --- Stoicism --- Overview, Philosophical --- Overviews, Philosophical --- Pharmacy Philosophies --- Philosophical Overviews --- Philosophies --- Philosophies, Pharmacy --- Philosophy, Pharmacy --- Evidence Based Health Care Management --- Evidence Based Healthcare Management --- Evidence Based Management, Health Care --- Evidence Based Management, Healthcare --- Evidence-Based Healthcare --- Evidence-Based Health Care --- Evidence Based Health Care --- Evidence Based Healthcare --- Evidence Based Practice --- Evidence-Based Health Cares --- Evidence-Based Healthcares --- Health Care, Evidence-Based --- Health Cares, Evidence-Based --- Healthcare, Evidence-Based --- Healthcares, Evidence-Based --- Medicine, Clinical --- Proxemics --- Behavioral Science --- Proxemic --- Science, Behavioral --- Sciences, Behavioral --- Health Workforce --- Methodological Studies --- Methodological Study --- Procedures --- Studies, Methodological --- Study, Methodological --- Method --- Procedure --- Medical Specialities --- Medical Specialties --- Medical Specialty --- Specialities, Medical --- Specialties, Medical --- Specialty, Medical --- Medical Speciality --- Speciality, Medical --- Psychiatrists --- Psychiatrist --- Medicine, Evidence-Based --- Evidence Based Medicine --- Medicine, Evidence Based --- Decision Support Techniques --- Evidence-Based Dentistry --- Evidence-Based Nursing --- Medical Philosophy --- Omega 3 Fatty Acids --- n-3 Oils --- n-3 PUFA --- n-3 Polyunsaturated Fatty Acid --- n3 Fatty Acid --- n3 Oils --- n3 PUFA --- n3 Polyunsaturated Fatty Acid --- N-3 Fatty Acid --- Omega-3 Fatty Acid --- Omega-3 Fatty Acids --- n-3 Fatty Acids --- n-3 Oil --- n3 Oil --- Acid, N-3 Fatty --- Acid, Omega-3 Fatty --- Fatty Acid, N-3 --- Fatty Acid, Omega-3 --- Fatty Acid, n3 --- N 3 Fatty Acid --- Oil, n-3 --- Oil, n3 --- Omega 3 Fatty Acid --- PUFA, n-3 --- PUFA, n3 --- n 3 Fatty Acids --- n 3 Oil --- n 3 Oils --- n 3 PUFA --- n 3 Polyunsaturated Fatty Acid --- Lipid --- Symptoms and General Pathology --- Disease. --- Philosophy, Medical. --- Psychiatry. --- methods. --- therapeutic use. --- Philosophy. --- Medicine and psychology --- Mental health --- Psychology, Pathological --- EBM (Medicine) --- Evidence-based healthcare --- Clinical medicine --- Systematic reviews (Medical research) --- Decision making

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