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This reprint contains original research and review articles describing recent advances in our understanding of the transcriptional regulation of cardiac development and disease mechanisms. All articles were originally published in the International Journal of Molecular Sciences (IJMS).

pluripotent stem cells --- cardiomyocytes --- cardiac tissue engineering --- human heart --- tissue maturation --- Wilms’ tumor suppressor 1 --- cardiomyocyte differentiation --- mouse embryonic stem cells --- myocardial infarction --- YAP --- TEAD1 --- Toll-like receptor --- heart --- TLR4 --- cardiomyocyte --- innate immune responses --- Wilms’ tumor suppressor 1 (Wt1) --- cardiac development --- coronary vessel formation --- transcriptional regulation --- cardiac malformation --- epicardium --- epicardial derived cells (EPDCs) --- epithelial mesenchymal transition (EMT) --- cardiac cell fate --- regeneration --- arrhythmogenic cardiomyopathy (ACM) --- lamin A/C --- atomic force microscopy (AFM) --- cell–cell adhesion --- neonatal rat ventricular fibroblasts (NRVF) --- tunneling nanotubes (TNT) --- gene therapy --- cardiovascular diseases --- cardiac regeneration --- cardiac reprogramming --- therapeutic angiogenesis --- growth factors --- reactive oxygen species --- apoptosis --- Bmp signaling --- Hand1 --- Smad --- heart development --- SH3BGR --- cardiac hypertrophy --- SRF signaling --- Hippo signaling --- cardiomyogenic differentiation --- cardiac mesenchymal stromal cell --- hydrogels --- histone deacetylase inhibitors --- translational studies --- gene expression and regulation --- cardiomyopathy --- heart failure --- reverse remodelling --- left ventricular assist device --- n/a --- Wilms' tumor suppressor 1 --- Wilms' tumor suppressor 1 (Wt1) --- cell-cell adhesion

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Polymers are the largest and most versatile class of biomaterials, being extensively applied for therapeutic applications. From natural to synthetic polymers, the possibilities to design and modify their physical-chemical properties make these systems of great interest in a wide range of biomedical applications as diverse as drug delivery systems, organ-on-a-chip, diagnostics, tissue engineering, and so on.In recent years, advances in the synthesis and modification of polymers and characterization techniques have allowed the design of novel biomaterials as well as the study of their biological behavior in vitro and in vivo.The purpose of this Special Issue is to highlight recent achievements in the synthesis and modification of polymers for biomedical applications for final applications in the field of biomedicine.

Technology: general issues --- Biotechnology --- biocomposite --- chitosan --- chlorhexidine --- coating --- hernia --- mesh infection --- nanoparticles --- PLGA --- polypropylene --- rifampicin --- 3D-bioprinting --- static mixer --- reactive hydrogel --- hyaluronic acid --- modified chitosan --- curcumin --- microwave --- interpenetrated polymer network --- semi-IPN --- methacrylated hyaluronic acid --- glycerylphytate --- mesenchymal stem cell --- bioadhesion --- biomaterials --- biomedical application --- healthcare system management --- innovation --- polymer based bioadhesive --- polymers --- magnetite nanoparticles --- Tween 80 --- synthesis --- nanotoxicology --- genotoxicity --- hemotoxicity --- soy protein --- film --- semiconductor --- biomaterial --- additive manufacturing --- sterilization --- medical devices --- bioabsorbable --- polymer --- biopolymer --- hydrogel --- microparticles --- dye release --- drug delivery system --- dual-responsiveness --- dendritic polyglycerol sulfates --- biofabrication --- microfluidics --- electrospinning --- 3D printing --- electrospraying --- natural polymers --- cell encapsulation --- polymeric prodrug --- dual-sensitive --- combination chemotherapy --- drug conjugation --- dextran --- hydrogels --- carboxymethyl cellulose --- succinoglycan --- metal coordination --- drug delivery --- swelling properties --- extracellular matrix --- external stimuli --- tissue maturation --- gelatin --- sodium carboxymethyl cellulose --- scaffold --- A549 cells --- freeze drying --- silicone rubber --- biomechanical --- hyper-elastic --- constitutive model --- FEA --- pH-sensitive hydrogel --- poly(acrylic acid) --- quartz crystal microbalance (QCM) --- ellipsometric measurement --- antibacterial activity --- Ganoderma lucidum --- polysaccharides --- cisplatin --- synergistic effect --- anti-lung cancer --- nanocellulose fiber --- low methoxyl pectin --- sodium alginate --- clindamycin --- pancreatic cancer --- gemcitabine --- controlled release --- non-woven sheet --- chemotherapy --- antitumor efficacy --- poly(L-lactic acid) --- antimicrobials agents --- amphiphilic block copolymer --- quaternized polymer --- hemolysis --- micelle --- black phosphorus --- polyetheretherketone --- lubrication properties --- antibacterial properties --- sensorineural hearing loss --- cochlear implants --- self-bending electrode arrays --- silicone rubber–hydrogel composites --- actuators --- swelling behavior --- curvature --- biocompatibility --- nanofibrous dura mater --- antifibrosis --- neuroprotection --- tetramethylpyrazine --- biocomposite --- chitosan --- chlorhexidine --- coating --- hernia --- mesh infection --- nanoparticles --- PLGA --- polypropylene --- rifampicin --- 3D-bioprinting --- static mixer --- reactive hydrogel --- hyaluronic acid --- modified chitosan --- curcumin --- microwave --- interpenetrated polymer network --- semi-IPN --- methacrylated hyaluronic acid --- glycerylphytate --- mesenchymal stem cell --- bioadhesion --- biomaterials --- biomedical application --- healthcare system management --- innovation --- polymer based bioadhesive --- polymers --- magnetite nanoparticles --- Tween 80 --- synthesis --- nanotoxicology --- genotoxicity --- hemotoxicity --- soy protein --- film --- semiconductor --- biomaterial --- additive manufacturing --- sterilization --- medical devices --- bioabsorbable --- polymer --- biopolymer --- hydrogel --- microparticles --- dye release --- drug delivery system --- dual-responsiveness --- dendritic polyglycerol sulfates --- biofabrication --- microfluidics --- electrospinning --- 3D printing --- electrospraying --- natural polymers --- cell encapsulation --- polymeric prodrug --- dual-sensitive --- combination chemotherapy --- drug conjugation --- dextran --- hydrogels --- carboxymethyl cellulose --- succinoglycan --- metal coordination --- drug delivery --- swelling properties --- extracellular matrix --- external stimuli --- tissue maturation --- gelatin --- sodium carboxymethyl cellulose --- scaffold --- A549 cells --- freeze drying --- silicone rubber --- biomechanical --- hyper-elastic --- constitutive model --- FEA --- pH-sensitive hydrogel --- poly(acrylic acid) --- quartz crystal microbalance (QCM) --- ellipsometric measurement --- antibacterial activity --- Ganoderma lucidum --- polysaccharides --- cisplatin --- synergistic effect --- anti-lung cancer --- nanocellulose fiber --- low methoxyl pectin --- sodium alginate --- clindamycin --- pancreatic cancer --- gemcitabine --- controlled release --- non-woven sheet --- chemotherapy --- antitumor efficacy --- poly(L-lactic acid) --- antimicrobials agents --- amphiphilic block copolymer --- quaternized polymer --- hemolysis --- micelle --- black phosphorus --- polyetheretherketone --- lubrication properties --- antibacterial properties --- sensorineural hearing loss --- cochlear implants --- self-bending electrode arrays --- silicone rubber–hydrogel composites --- actuators --- swelling behavior --- curvature --- biocompatibility --- nanofibrous dura mater --- antifibrosis --- neuroprotection --- tetramethylpyrazine

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Polymers are the largest and most versatile class of biomaterials, being extensively applied for therapeutic applications. From natural to synthetic polymers, the possibilities to design and modify their physical-chemical properties make these systems of great interest in a wide range of biomedical applications as diverse as drug delivery systems, organ-on-a-chip, diagnostics, tissue engineering, and so on.In recent years, advances in the synthesis and modification of polymers and characterization techniques have allowed the design of novel biomaterials as well as the study of their biological behavior in vitro and in vivo.The purpose of this Special Issue is to highlight recent achievements in the synthesis and modification of polymers for biomedical applications for final applications in the field of biomedicine.

biocomposite --- chitosan --- chlorhexidine --- coating --- hernia --- mesh infection --- nanoparticles --- PLGA --- polypropylene --- rifampicin --- 3D-bioprinting --- static mixer --- reactive hydrogel --- hyaluronic acid --- modified chitosan --- curcumin --- microwave --- interpenetrated polymer network --- semi-IPN --- methacrylated hyaluronic acid --- glycerylphytate --- mesenchymal stem cell --- bioadhesion --- biomaterials --- biomedical application --- healthcare system management --- innovation --- polymer based bioadhesive --- polymers --- magnetite nanoparticles --- Tween 80 --- synthesis --- nanotoxicology --- genotoxicity --- hemotoxicity --- soy protein --- film --- semiconductor --- biomaterial --- additive manufacturing --- sterilization --- medical devices --- bioabsorbable --- polymer --- biopolymer --- hydrogel --- microparticles --- dye release --- drug delivery system --- dual-responsiveness --- dendritic polyglycerol sulfates --- biofabrication --- microfluidics --- electrospinning --- 3D printing --- electrospraying --- natural polymers --- cell encapsulation --- polymeric prodrug --- dual-sensitive --- combination chemotherapy --- drug conjugation --- dextran --- hydrogels --- carboxymethyl cellulose --- succinoglycan --- metal coordination --- drug delivery --- swelling properties --- extracellular matrix --- external stimuli --- tissue maturation --- gelatin --- sodium carboxymethyl cellulose --- scaffold --- A549 cells --- freeze drying --- silicone rubber --- biomechanical --- hyper-elastic --- constitutive model --- FEA --- pH-sensitive hydrogel --- poly(acrylic acid) --- quartz crystal microbalance (QCM) --- ellipsometric measurement --- antibacterial activity --- Ganoderma lucidum --- polysaccharides --- cisplatin --- synergistic effect --- anti-lung cancer --- nanocellulose fiber --- low methoxyl pectin --- sodium alginate --- clindamycin --- pancreatic cancer --- gemcitabine --- controlled release --- non-woven sheet --- chemotherapy --- antitumor efficacy --- poly(L-lactic acid) --- antimicrobials agents --- amphiphilic block copolymer --- quaternized polymer --- hemolysis --- micelle --- black phosphorus --- polyetheretherketone --- lubrication properties --- antibacterial properties --- sensorineural hearing loss --- cochlear implants --- self-bending electrode arrays --- silicone rubber–hydrogel composites --- actuators --- swelling behavior --- curvature --- biocompatibility --- nanofibrous dura mater --- antifibrosis --- neuroprotection --- tetramethylpyrazine