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The road of acceptance of oncologic thermotherapy/hyperthermia as a synergistic modality in combination with standard oncologic therapies is still bumpy. This is partially due to the lack of level I evidence from international, multicentric, randomized clinical trials including large patient numbers and a long term follow-up. Therefore we need more level I EVIDENCE from clinical trials, we need HARMONISATION and global acceptance for existing technologies and a common language understood by all stakeholders and we need INNOVATION in the fields of biology, clinics and technology to move thermotherapy/hyperthermia forward. This is the main focus of this reprint. In this reprintyou find carefully selected and peer-reviewed contributions from Africa, America, Asia, and Europe. The published papers from leading scientists from all over the world covering a broad range of timely research topics might also help to strengthen thermotherapy on a global level.

Medicine --- Oncology --- perfusion estimation --- temperature monitoring --- conductivity reconstruction --- systems medicine --- immune system in silico --- perceptron --- antigen pattern --- danger signal --- fractionation --- immune response --- head and neck cancer --- hyperthermia --- reirradiation --- treatment outcome --- hyperthermia treatment planning --- adaptive planning --- temperature optimization --- low-middle-income group countries --- cancer --- radiotherapy --- chemotherapy --- recurrent breast cancers --- cervical cancer --- head and neck cancers --- cost-effective --- meta-analysis --- intensity-modulated radiotherapy --- prostate cancer --- thermal dose --- thermometric parameters --- preclinical data --- clinical evidence --- modulated electro-hyperthermia --- abscopal effect --- locally advanced cervical cancer --- resource-constrained setting --- radiosensitiser --- rectal cancer --- chemoradiotherapy --- tumour control --- loco-regional hyperthermia --- oncology --- cellular selection --- bioelectromagnetics --- complexity --- immune-effects --- moderate hyperthermia --- deep hyperthermia --- radiative hyperthermia --- patterns of care --- reimbursement --- regional hyperthermia --- neoadjuvant chemoradiation --- survival --- induced --- brachytherapy --- prostatic neoplasms --- interstitial hyperthermia --- treatment plan optimization --- prostate --- thermoradiotherapy --- linear quadratic model --- biological modeling --- thermal dosimetry --- hypoxia --- radiation therapy --- reoxygenation --- perfusion --- oxygen consumption rate --- local tumor control --- biomarker --- immune phenotype --- hyperthermia treatment sequence --- breast cancer --- immune checkpoint molecules --- dendritic cell activation --- n/a

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The road of acceptance of oncologic thermotherapy/hyperthermia as a synergistic modality in combination with standard oncologic therapies is still bumpy. This is partially due to the lack of level I evidence from international, multicentric, randomized clinical trials including large patient numbers and a long term follow-up. Therefore we need more level I EVIDENCE from clinical trials, we need HARMONISATION and global acceptance for existing technologies and a common language understood by all stakeholders and we need INNOVATION in the fields of biology, clinics and technology to move thermotherapy/hyperthermia forward. This is the main focus of this reprint. In this reprintyou find carefully selected and peer-reviewed contributions from Africa, America, Asia, and Europe. The published papers from leading scientists from all over the world covering a broad range of timely research topics might also help to strengthen thermotherapy on a global level.

Medicine --- Oncology --- perfusion estimation --- temperature monitoring --- conductivity reconstruction --- systems medicine --- immune system in silico --- perceptron --- antigen pattern --- danger signal --- fractionation --- immune response --- head and neck cancer --- hyperthermia --- reirradiation --- treatment outcome --- hyperthermia treatment planning --- adaptive planning --- temperature optimization --- low-middle-income group countries --- cancer --- radiotherapy --- chemotherapy --- recurrent breast cancers --- cervical cancer --- head and neck cancers --- cost-effective --- meta-analysis --- intensity-modulated radiotherapy --- prostate cancer --- thermal dose --- thermometric parameters --- preclinical data --- clinical evidence --- modulated electro-hyperthermia --- abscopal effect --- locally advanced cervical cancer --- resource-constrained setting --- radiosensitiser --- rectal cancer --- chemoradiotherapy --- tumour control --- loco-regional hyperthermia --- oncology --- cellular selection --- bioelectromagnetics --- complexity --- immune-effects --- moderate hyperthermia --- deep hyperthermia --- radiative hyperthermia --- patterns of care --- reimbursement --- regional hyperthermia --- neoadjuvant chemoradiation --- survival --- induced --- brachytherapy --- prostatic neoplasms --- interstitial hyperthermia --- treatment plan optimization --- prostate --- thermoradiotherapy --- linear quadratic model --- biological modeling --- thermal dosimetry --- hypoxia --- radiation therapy --- reoxygenation --- perfusion --- oxygen consumption rate --- local tumor control --- biomarker --- immune phenotype --- hyperthermia treatment sequence --- breast cancer --- immune checkpoint molecules --- dendritic cell activation