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This book presents some of the latest available information on automated ECG analysis written by many of the leading researchers in the field. It contains a historical introduction, an outline of the latest international standards for signal processing and communications and then an exciting variety of studies on electrophysiological modelling, ECG Imaging, artificial intelligence applied to resting and ambulatory ECGs, body surface mapping, big data in ECG based prediction, enhanced reliability of patient monitoring, and atrial abnormalities on the ECG. It provides an extremely valuable contribution to the field.

Medicine --- electrocardiographic imaging (ECGI) --- heart failure (HF) --- cardiac resynchronization therapy (CRT) --- ultrasound --- strain --- speckle tracking echocardiography --- in silico --- electrophysiology --- electrocardiogram --- ECG --- cardiac disease --- arrhythmia --- ischemia --- standardization --- computerized ECG --- personalized medicine --- telemedicine --- digital ECG data interchange protocol --- eHealth --- ECG equipment --- computerized electrocardiograph --- ECG analysis algorithms --- computerized ECG interpretation --- interatrial block --- partial interatrial block --- advanced interatrial block --- atypical patterns --- electrocardiogram (ECG) --- automated ECG analysis --- CSE study --- age --- sex --- race --- historical aspects --- electronic cohort --- mortality --- big data --- telehealth --- alarm fatigue --- annotation of ECG data --- arrhythmia alarms --- intensive care unit --- patient monitoring --- ambulatory ECG --- machine learning --- deep learning --- pattern recognition --- noise reduction --- Holter ECG --- ECG interpretation --- artificial intelligence --- body surface mapping --- electrocardiographic imaging --- image processing --- clinical applications

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This book outlines some new advances in genetics, clinical evaluation, localization, therapy (newly including immunotherapy) of pheochromocytoma and paraganglioma including their metastatic counterparts. Well-known and experienced clinicians and scientists contributed to this book to include some novel approaches to these tumors. This book will serve to various health care professionals from different subspecialties, but mainly oncologists, endocrinologists, endocrine surgeons, pediatricians, and radiologists. This book shows that the field of pheochromocytoma/paraganglioma is evolving and a significant progress has been made in last 5 years requiring that health care professionals and scientists will learns new information and implement it in their clinical practice or scientific work, respectively. This book should not be missed by anybody who is focusing on neuroendocrine tumors, their newest evaluation and treatment.

polycythemia --- peptide receptor radiotherapy --- n/a --- vasculogenesis --- catecholamines --- neuroendocrine --- GTV --- adaptive immunity --- therapy resistance --- histology --- transgenic mice --- cryoablation --- spheroids --- energy metabolism --- somatostatinoma --- angiogenesis --- pheochromocytoma --- SDHD --- percutaneous ethanol injection --- metanephrines --- SDHB --- global longitudinal strain --- mutation --- normetanephrines --- catecholamine --- PASS --- PGL --- 177Lu-DOTATATE --- chromosomal alteration --- speckle-tracking echocardiography --- lL-6 --- dog --- percutaneous ablation --- stem-like tumor cells --- EPAS1 --- neural crest --- fluorescence imaging --- neutrophil --- xenograft --- inflammation --- head and neck --- weighted standard deviation --- FGF21 --- calorimetry --- HIF --- average real variability --- next-generation sequencing --- adrenocortical carcinoma --- carotid body --- hypoxia-inducible factor --- paraganglioma --- succinate dehydrogenase --- blood pressure variability --- arrhythmia --- mortality --- NF1 --- toll-like receptor --- GAPP --- NET --- subclinical systolic dysfunction --- pheochromocytoma and paraganglioma --- PET-CT --- pan-cancer analysis --- mouse pheochromocytoma cells --- innate immunity --- neurogenesis --- neuroendocrine tumor --- obesity --- hypotension --- hypoxia --- CNV detection --- 18F-FDOPA --- comparative genomics --- adrenomedullary function --- PCC --- pathogen-associated molecular patterns --- adrenal tumor --- radiotherapy --- 11C-hydroxy-ephedrine --- radiofrequency ablation --- PPGL --- minimally invasive procedure --- sporadic --- diabetes mellitus --- adrenal incidentaloma --- germline mutation --- immunotherapy --- VHL --- immunohistochemistry --- metastatic OR malignant pheochromocytoma --- erythropoietin --- postoperative --- targeted therapy --- PRRT --- metastatic --- mitochondria --- T cell --- TCA cycle --- meta-analysis --- pseudohypoxia --- ectopic secretion --- radiosensitization --- chromogranin A --- hereditary --- hypertension --- PET --- phosphorylation tyrosine hydroxylase