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This Special Issue on “Blood-Derived Products for Tissue Repair and Regeneration” reveals the evolution and diversity of platelet rich plasma (PRP) technologies, which includes experimental research on novel formulations, the creation of combination therapies, and the exploration of potential modifiers of PRPs, as well as efficacy of PRP therapies in clinical veterinary and human applications. Scientist and clinicians are now starting to develop different treatments based on their reinterpretation of the traditional roles of platelets and plasma, and the current Issue has provided a forum for sharing research and ways of understanding the associated medicinal benefits from different points of view. The research interest in this area has covered different medical disciplines, such as ophthalmology, dentistry, orthopedics, and sports medicine.
n/a --- biomaterial --- redifferentiation --- regenerative medicine --- skeletal muscle regeneration --- furcation defects --- Platelet-Rich Plasma (PRP) --- PRP --- fracture --- fibrin sealant --- periodontal surgery --- bone regeneration --- serum derived from plasma rich in growth factors (s-PRGF) --- cartilage repair --- myofibroblasts --- autologous platelet concentrates --- burns --- satellite cells --- articular cartilage --- stem cell niche --- wound healing --- quantification --- growth factors --- biologics --- platelet rich plasma --- meniscus --- adipose tissue --- Carprofen --- platelet-rich fibrin --- platelets --- hyperacute serum --- bone defects --- serum eye drops --- corneal epithelial defect --- fibrosis --- dog --- myoblasts --- differentiation --- chronic meniscal lesion --- horizontal meniscal tear --- PRGF --- collagen hydrogels --- periodontal defects --- bone grafting material --- composition --- cell therapy --- bone healing --- tissue healing --- trephination --- plasma rich plasma (PRP) --- bone repair --- plasma rich in growth factors --- knee arthrosis --- meniscus tear --- cornea regeneration --- wrist osteoarthritis --- periosteal sheet --- Platelet-Poor Plasma (PPP) --- platelet-rich plasma --- microfat --- bone grafting --- hyaluronic acid (NaHA) --- periodontal regeneration --- meniscus repair --- photobiomodulation therapy --- growth --- myogenesis --- blood derived products --- low-level laser therapy
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The book is a collection of original research and review articles addressing the intriguing field of the cellular and molecular players involved in muscle homeostasis and regeneration. One of the most ambitious aspirations of modern medical science is the possibility of regenerating any damaged part of the body, including skeletal muscle. This desire has prompted clinicians and researchers to search for innovative technologies aimed at replacing organs and tissues that are compromised. In this context, the papers, collected in this book, addressing a specific aspects of muscle homeostasis and regeneration under physiopathologic conditions, will help us to better understand the underlying mechanisms of muscle healing and will help to design more appropriate therapeutic approaches to improve muscle regeneration and to counteract muscle diseases.
Research & information: general --- Biology, life sciences --- lysine --- mTORC1 --- satellite cells --- proliferation --- skeletal muscle growth --- muscle satellite cell --- transthyretin --- thyroid hormone --- myogenesis --- exosomes --- skeletal muscle --- genotype --- genetic variation --- muscle phenotypes --- sarcopenia --- aging --- calcium homeostasis --- hibernation --- mitochondria --- sarcoplasmic reticulum --- Acvr1b --- Tgfbr1 --- myostatin --- Col1a1 --- fibrosis --- atrophy --- IGF2R --- muscle homeostasis --- inflammation --- muscular dystrophy --- pericytes --- macrophages --- Nfix --- phagocytosis --- RhoA-ROCK1 --- splicing isoforms --- CRISPR-Cas9 --- exon deletion --- NF-Y --- muscle differentiation --- C2C12 cells --- denervation --- neuromuscular junction --- heavy resistance exercise --- acetylcholine receptor --- cell culture --- neonatal myosin --- neural cell adhesion molecule --- biomarkers --- mitophagy --- mitochondrial dynamics --- mitochondrial quality control --- mitochondrial-derived vesicles (MDVs) --- mitochondrial-lysosomal axis --- Hibernation --- electron microscopy --- immunocytochemistry --- α-smooth muscle actin --- confocal microscopy --- connexin 43 --- connexin 26 --- gap junctions --- myofibroblasts --- Platelet-Rich Plasma --- transforming growth factor (TGF)-β1 --- muscle regeneration --- inflammatory response --- cell precursors --- experimental methods --- stem cell markers --- muscles --- heterotopic ossification --- skeletal muscle stem and progenitor cells --- HO precursors --- muscle atrophy --- septicemia --- mitochondrial fusion --- mitochondrial fission --- iPSC --- extracellular vesicles --- Drosophila --- muscle --- genetic control --- muscle diversification --- fascicle --- myofiber --- myofibril --- sarcomere --- hypertrophy --- hyperplasia --- splitting --- radial growth --- longitudinal growth --- exercise --- muscle stem cells --- stem cells niche --- neuromuscular disorders --- Duchenne muscular dystrophy --- pharmacological approach --- single-cell --- mass cytometry --- skeletal muscle regeneration --- skeletal muscle homeostasis --- fibro/adipogenic progenitors --- myogenic progenitors --- muscle populations --- evolution --- metazoans --- differentiation --- transdifferentiation --- muscle precursors --- regenerative medicine --- stem cells --- FAPs --- tissue niche --- growth factors --- muscle pathology --- lysine --- mTORC1 --- satellite cells --- proliferation --- skeletal muscle growth --- muscle satellite cell --- transthyretin --- thyroid hormone --- myogenesis --- exosomes --- skeletal muscle --- genotype --- genetic variation --- muscle phenotypes --- sarcopenia --- aging --- calcium homeostasis --- hibernation --- mitochondria --- sarcoplasmic reticulum --- Acvr1b --- Tgfbr1 --- myostatin --- Col1a1 --- fibrosis --- atrophy --- IGF2R --- muscle homeostasis --- inflammation --- muscular dystrophy --- pericytes --- macrophages --- Nfix --- phagocytosis --- RhoA-ROCK1 --- splicing isoforms --- CRISPR-Cas9 --- exon deletion --- NF-Y --- muscle differentiation --- C2C12 cells --- denervation --- neuromuscular junction --- heavy resistance exercise --- acetylcholine receptor --- cell culture --- neonatal myosin --- neural cell adhesion molecule --- biomarkers --- mitophagy --- mitochondrial dynamics --- mitochondrial quality control --- mitochondrial-derived vesicles (MDVs) --- mitochondrial-lysosomal axis --- Hibernation --- electron microscopy --- immunocytochemistry --- α-smooth muscle actin --- confocal microscopy --- connexin 43 --- connexin 26 --- gap junctions --- myofibroblasts --- Platelet-Rich Plasma --- transforming growth factor (TGF)-β1 --- muscle regeneration --- inflammatory response --- cell precursors --- experimental methods --- stem cell markers --- muscles --- heterotopic ossification --- skeletal muscle stem and progenitor cells --- HO precursors --- muscle atrophy --- septicemia --- mitochondrial fusion --- mitochondrial fission --- iPSC --- extracellular vesicles --- Drosophila --- muscle --- genetic control --- muscle diversification --- fascicle --- myofiber --- myofibril --- sarcomere --- hypertrophy --- hyperplasia --- splitting --- radial growth --- longitudinal growth --- exercise --- muscle stem cells --- stem cells niche --- neuromuscular disorders --- Duchenne muscular dystrophy --- pharmacological approach --- single-cell --- mass cytometry --- skeletal muscle regeneration --- skeletal muscle homeostasis --- fibro/adipogenic progenitors --- myogenic progenitors --- muscle populations --- evolution --- metazoans --- differentiation --- transdifferentiation --- muscle precursors --- regenerative medicine --- stem cells --- FAPs --- tissue niche --- growth factors --- muscle pathology
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The book is a collection of original research and review articles addressing the intriguing field of the cellular and molecular players involved in muscle homeostasis and regeneration. One of the most ambitious aspirations of modern medical science is the possibility of regenerating any damaged part of the body, including skeletal muscle. This desire has prompted clinicians and researchers to search for innovative technologies aimed at replacing organs and tissues that are compromised. In this context, the papers, collected in this book, addressing a specific aspects of muscle homeostasis and regeneration under physiopathologic conditions, will help us to better understand the underlying mechanisms of muscle healing and will help to design more appropriate therapeutic approaches to improve muscle regeneration and to counteract muscle diseases.
Research & information: general --- Biology, life sciences --- lysine --- mTORC1 --- satellite cells --- proliferation --- skeletal muscle growth --- muscle satellite cell --- transthyretin --- thyroid hormone --- myogenesis --- exosomes --- skeletal muscle --- genotype --- genetic variation --- muscle phenotypes --- sarcopenia --- aging --- calcium homeostasis --- hibernation --- mitochondria --- sarcoplasmic reticulum --- Acvr1b --- Tgfbr1 --- myostatin --- Col1a1 --- fibrosis --- atrophy --- IGF2R --- muscle homeostasis --- inflammation --- muscular dystrophy --- pericytes --- macrophages --- Nfix --- phagocytosis --- RhoA-ROCK1 --- splicing isoforms --- CRISPR-Cas9 --- exon deletion --- NF-Y --- muscle differentiation --- C2C12 cells --- denervation --- neuromuscular junction --- heavy resistance exercise --- acetylcholine receptor --- cell culture --- neonatal myosin --- neural cell adhesion molecule --- biomarkers --- mitophagy --- mitochondrial dynamics --- mitochondrial quality control --- mitochondrial-derived vesicles (MDVs) --- mitochondrial-lysosomal axis --- Hibernation --- electron microscopy --- immunocytochemistry --- α-smooth muscle actin --- confocal microscopy --- connexin 43 --- connexin 26 --- gap junctions --- myofibroblasts --- Platelet-Rich Plasma --- transforming growth factor (TGF)-β1 --- muscle regeneration --- inflammatory response --- cell precursors --- experimental methods --- stem cell markers --- muscles --- heterotopic ossification --- skeletal muscle stem and progenitor cells --- HO precursors --- muscle atrophy --- septicemia --- mitochondrial fusion --- mitochondrial fission --- iPSC --- extracellular vesicles --- Drosophila --- muscle --- genetic control --- muscle diversification --- fascicle --- myofiber --- myofibril --- sarcomere --- hypertrophy --- hyperplasia --- splitting --- radial growth --- longitudinal growth --- exercise --- muscle stem cells --- stem cells niche --- neuromuscular disorders --- Duchenne muscular dystrophy --- pharmacological approach --- single-cell --- mass cytometry --- skeletal muscle regeneration --- skeletal muscle homeostasis --- fibro/adipogenic progenitors --- myogenic progenitors --- muscle populations --- evolution --- metazoans --- differentiation --- transdifferentiation --- muscle precursors --- regenerative medicine --- stem cells --- FAPs --- tissue niche --- growth factors --- muscle pathology
Choose an application
The book is a collection of original research and review articles addressing the intriguing field of the cellular and molecular players involved in muscle homeostasis and regeneration. One of the most ambitious aspirations of modern medical science is the possibility of regenerating any damaged part of the body, including skeletal muscle. This desire has prompted clinicians and researchers to search for innovative technologies aimed at replacing organs and tissues that are compromised. In this context, the papers, collected in this book, addressing a specific aspects of muscle homeostasis and regeneration under physiopathologic conditions, will help us to better understand the underlying mechanisms of muscle healing and will help to design more appropriate therapeutic approaches to improve muscle regeneration and to counteract muscle diseases.
lysine --- mTORC1 --- satellite cells --- proliferation --- skeletal muscle growth --- muscle satellite cell --- transthyretin --- thyroid hormone --- myogenesis --- exosomes --- skeletal muscle --- genotype --- genetic variation --- muscle phenotypes --- sarcopenia --- aging --- calcium homeostasis --- hibernation --- mitochondria --- sarcoplasmic reticulum --- Acvr1b --- Tgfbr1 --- myostatin --- Col1a1 --- fibrosis --- atrophy --- IGF2R --- muscle homeostasis --- inflammation --- muscular dystrophy --- pericytes --- macrophages --- Nfix --- phagocytosis --- RhoA-ROCK1 --- splicing isoforms --- CRISPR-Cas9 --- exon deletion --- NF-Y --- muscle differentiation --- C2C12 cells --- denervation --- neuromuscular junction --- heavy resistance exercise --- acetylcholine receptor --- cell culture --- neonatal myosin --- neural cell adhesion molecule --- biomarkers --- mitophagy --- mitochondrial dynamics --- mitochondrial quality control --- mitochondrial-derived vesicles (MDVs) --- mitochondrial-lysosomal axis --- Hibernation --- electron microscopy --- immunocytochemistry --- α-smooth muscle actin --- confocal microscopy --- connexin 43 --- connexin 26 --- gap junctions --- myofibroblasts --- Platelet-Rich Plasma --- transforming growth factor (TGF)-β1 --- muscle regeneration --- inflammatory response --- cell precursors --- experimental methods --- stem cell markers --- muscles --- heterotopic ossification --- skeletal muscle stem and progenitor cells --- HO precursors --- muscle atrophy --- septicemia --- mitochondrial fusion --- mitochondrial fission --- iPSC --- extracellular vesicles --- Drosophila --- muscle --- genetic control --- muscle diversification --- fascicle --- myofiber --- myofibril --- sarcomere --- hypertrophy --- hyperplasia --- splitting --- radial growth --- longitudinal growth --- exercise --- muscle stem cells --- stem cells niche --- neuromuscular disorders --- Duchenne muscular dystrophy --- pharmacological approach --- single-cell --- mass cytometry --- skeletal muscle regeneration --- skeletal muscle homeostasis --- fibro/adipogenic progenitors --- myogenic progenitors --- muscle populations --- evolution --- metazoans --- differentiation --- transdifferentiation --- muscle precursors --- regenerative medicine --- stem cells --- FAPs --- tissue niche --- growth factors --- muscle pathology
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