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Cells play significant roles in our day to day life. However, the interactions of cells, the cellular responses of organelles to molecules, and their intracellular behaviour, are still not fully understood. To better understand the physiological interactions among molecules, organelles, and cells, the ensemble measurement of (on average, millions of) cells cannot provide detailed information. However, for example, research concerning the differentiation behaviors of stem cells or the metastatic processes of tumour initiation requires detailed information. Understanding genomic sequence information at a single cell level can promote an understanding of how individual parts of a cell are integrated in time and space to form dynamic cellular processes. The relationship between cellular heterogeneity and signaling pathway regulation may result in an understanding of disease states that can potentially drive therapeutic interventions. Thus single cell analysis (SCA) has been emerging as a powerful method of investigating exciting new insights into genomics, fluxomics, proteomics, and systems biology.

Single cell proteins --- Biotechnology.

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Single cell proteins

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Single cell proteins --- Food --- Aliments --- Research --- Recherche

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Science: general issues --- Biology, life sciences --- single-cell sequencing --- Single-Cell isolation --- single-cell fluorescence in situ hybridization --- Single-cell multi-omics --- Single-cell microfluidics --- single-cell experimental design --- single-cell bioinformatics --- cell cycling and cell size --- Single-cell mass spectrometry --- Cell heterogeneity

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Featuring recognized academic and industrial experts in this cutting-edge field, this book reviews single cell oils (SCO) currently in the market. The text mainly focuses on the production of the long chain polyunsaturated fatty acids, Arachidonic acid, and Docosahexaenoinc acid. All chapters provide up to date references for navigating the vast amount of historic data available in the field. The authors provide real world examples of the commercial development and applications of various SCO in a variety of fields, from food ingredients and disease treatment to aquaculture and fish farming.The highlight of the book is perhaps the first chapter in which Colin Ratledge, a world renowned expert in SCO and lipid biochemistry, gives an interesting and informative overview on the history of SCO development, together with his perspectives on the future of this industry in light of competition arising from genetically modified plant oils. Zvi Cohen, a renowned expert in PUFA-producing microalgae, describes some of his metabolic studies on PUFA production and TAG biosynthesis. Chapter 10 deals with EPA-producing microalgae and some cultivation strategies for their large scale production. This chapter includes a number of tables summarizing the various organisms under investigation which I found to be of great use. Since the development of EPA single cell oils is still in its infancy, this chapter is quite helpful for researchers thinking along those lines.

Single cell lipids --- 547.915 --- Fats, Single cell --- Lipids, Single cell --- Microbial biomass lipids --- Oils, Single cell --- Single cell fats --- Single cell oils --- Biomass chemicals --- Microbial lipids --- Oils and fats --- 547.915 Fats. Oils. Lipids --- Fats. Oils. Lipids --- Engineering --- Food Science and Technology --- Single cell lipids.