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Testicular cancer (TC) is the most frequent solid malignancy in young men aged between 15 and 40 years. The worldwide incidence is about 7.5 per 100,000 subjects, but the rates vary considerably between countries and ethnic groups. About 95% of all TCs are represented by testicular germ cell tumors (TGCTs), which include seminoma and non-seminoma histological types. It has been reported that about 18,000 European subjects over reproductive age develop a TGCT every year and its incidence is increasing in several countries over the past 50 years. Early diagnosis and modern treatment have resulted in over 95% survival rate and improved quality of life in testicular cancer survivors. However, the benefits of cancer treatments may hide some risks. In fact, possible side effects can be developed during the treatment itself or later from months to years after the completion of therapy, persisting during the whole life. Therefore, TGCT survivors frequently complain a number of healthy problems such as infertility, hypogonadism, metabolic syndrome, osteoporosis, sexual disorders, depressed mood, and in general impaired quality of life. This aspect is the most serious and potentially life threatening effect in TGCT survivors. Many risk factors have been studied as a pre-disposing factor in the development of this cancer, but only for some there is a high level of evidence. In recent times, progressive increases in the incidence of male reproductive disorders inclusive of hypospadias, cryptorchidism, poor semen quality, and testicular cancer, suggested a common foetal origin. The central hypothesis of this observation asserted that these disorders may all collectively signify testicular dysgenesis syndrome (TDS). It is generally assumed that the development of TGCT is under endocrine control. In particular, unbalanced androgen/estrogen levels and/or activity during embryogenesis, are believed to represent the key events for TGCT development and progression. Furthermore, recent evidence has suggested genetic association of TGCT with variations in genes involved in hypothalamic-pituitary-testicular axis and steroidogenic enzymes. Therefore, hormonal carcinogenesis is an important and controversial area of current research in TGCT, and further attention is given to endocrine environment influencing testicular development during foetal life. The objective of this Research Topic is to group a collection of articles focused on new and more recent insights about TGCT.

testis cancer --- genetics --- male infertility --- sexual function --- cancer treatment

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Testicular cancer (TC) is the most frequent solid malignancy in young men aged between 15 and 40 years. The worldwide incidence is about 7.5 per 100,000 subjects, but the rates vary considerably between countries and ethnic groups. About 95% of all TCs are represented by testicular germ cell tumors (TGCTs), which include seminoma and non-seminoma histological types. It has been reported that about 18,000 European subjects over reproductive age develop a TGCT every year and its incidence is increasing in several countries over the past 50 years. Early diagnosis and modern treatment have resulted in over 95% survival rate and improved quality of life in testicular cancer survivors. However, the benefits of cancer treatments may hide some risks. In fact, possible side effects can be developed during the treatment itself or later from months to years after the completion of therapy, persisting during the whole life. Therefore, TGCT survivors frequently complain a number of healthy problems such as infertility, hypogonadism, metabolic syndrome, osteoporosis, sexual disorders, depressed mood, and in general impaired quality of life. This aspect is the most serious and potentially life threatening effect in TGCT survivors. Many risk factors have been studied as a pre-disposing factor in the development of this cancer, but only for some there is a high level of evidence. In recent times, progressive increases in the incidence of male reproductive disorders inclusive of hypospadias, cryptorchidism, poor semen quality, and testicular cancer, suggested a common foetal origin. The central hypothesis of this observation asserted that these disorders may all collectively signify testicular dysgenesis syndrome (TDS). It is generally assumed that the development of TGCT is under endocrine control. In particular, unbalanced androgen/estrogen levels and/or activity during embryogenesis, are believed to represent the key events for TGCT development and progression. Furthermore, recent evidence has suggested genetic association of TGCT with variations in genes involved in hypothalamic-pituitary-testicular axis and steroidogenic enzymes. Therefore, hormonal carcinogenesis is an important and controversial area of current research in TGCT, and further attention is given to endocrine environment influencing testicular development during foetal life. The objective of this Research Topic is to group a collection of articles focused on new and more recent insights about TGCT.

Medicine --- Endocrinology --- testis cancer --- genetics --- male infertility --- sexual function --- cancer treatment

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Sexual disorders --- Sexual health --- Sexual Dysfunction, Physiological. --- Sexual Dysfunctions, Psychological. --- Sexual disorders. --- Sexual health. --- Hygiene, Sexual --- Hygiene, Social --- Sex hygiene --- Sexual hygiene --- Social hygiene --- Health --- Sex instruction --- Sexually transmitted diseases --- Sex disorders --- Sexual diseases --- Sex (Biology) --- Psychosexual disorders --- Frigidity --- Hypoactive Sexual Desire Disorder --- Orgasmic Disorder --- Psychosexual Disorders --- Psychosexual Dysfunctions --- Sexual Arousal Disorder --- Sexual Aversion Disorder --- Arousal Disorders, Sexual --- Aversion Disorders, Sexual --- Disorder, Psychosexual --- Disorders, Orgasmic --- Disorders, Psychosexual --- Disorders, Sexual Arousal --- Disorders, Sexual Aversion --- Dysfunction, Psychological Sexual --- Dysfunction, Psychosexual --- Dysfunctions, Psychological Sexual --- Dysfunctions, Psychosexual --- Orgasmic Disorders --- Psychological Sexual Dysfunction --- Psychological Sexual Dysfunctions --- Psychosexual Disorder --- Psychosexual Dysfunction --- Sexual Arousal Disorders --- Sexual Aversion Disorders --- Sexual Dysfunction, Psychological --- Sexual Health --- Sex Disorders --- Sexual Disorders, Physiological --- Sexual Dysfunctions, Physiological --- Physiological Sexual Disorder --- Physiological Sexual Disorders --- Physiological Sexual Dysfunction --- Physiological Sexual Dysfunctions --- Sexual Disorder, Physiological --- urology --- impotence --- sexual function --- erectile dysfunction

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A Scientific Book Club selection, this comprehensive account of the nature and function of the hormones in the processes of sex and reproduction.Originally published in 1942.The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Reproduction. --- Hormones. --- Abortion, Threatened. --- Addison's disease. --- Adrenal gland. --- Androgen. --- Anovulatory cycle. --- Birth control. --- Birth. --- Childbirth. --- Circulatory system. --- Corpus luteum. --- Egg cell. --- Embryo. --- Embryology. --- Endocrine Research. --- Endocrine gland. --- Endocrine system. --- Endocrinology. --- Endometrium. --- Estrogen. --- Estrogens, Synthetic. --- Estrous cycle. --- Fallopian tube. --- Fertile Period. --- Fertilisation. --- Fetus. --- Follicle-stimulating hormone. --- Follicular phase. --- Germ cell. --- Gestation. --- Gland. --- Gonadotropin. --- Gynaecology. --- Hormone. --- Human reproduction. --- Hypogonadism. --- Immortalised cell line. --- Implantation (human embryo). --- Inbreeding. --- Interstitial cell. --- Lactation. --- Libido. --- Luteal phase. --- Male reproductive system. --- Mammal. --- Mammalian reproduction. --- Mammary gland. --- Mating. --- Menopause. --- Menorrhagia. --- Menstrual cycle. --- Menstrual disorder. --- Menstruation. --- Miscarriage. --- Nipple. --- Obstetrics and gynaecology. --- Oophorectomy. --- Ovarian Cycle. --- Ovarian follicle. --- Ovary. --- Oviduct. --- Ovulation. --- Pancreatic hormone. --- Parathyroid gland. --- Parthenogenesis. --- Physiology. --- Pituitary gland. --- Placenta. --- Pregnancy test. --- Pregnancy. --- Pregnanediol. --- Progesterone. --- Progestin. --- Prolactin. --- Prostate. --- Reproductive system. --- Secondary sex characteristic. --- Secretion. --- Semen. --- Seminal vesicle. --- Sex organ. --- Sex steroid. --- Sexual dimorphism. --- Sexual function. --- Sexual reproduction. --- Sperm. --- Spermatogenesis. --- Spermatozoon. --- Spermine. --- Sterility (physiology). --- Steroid hormone. --- Swinging (sexual practice). --- Testicle. --- The Science of Life. --- Trophic hormone. --- Umbilical cord. --- Uterine gland. --- Uterus. --- Vagina. --- Vaginal bleeding.

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Until 1912 the association of Jung and Freud was very close, and Jung was regarded as one of the leading practitioners of psychoanalysis. Subsequently, however, Jung began to differ with Freud, and his public criticism of psychoanalysis led to a formal rupture between them. The papers in this volume contain the essentials of that criticism, especially "The Theory of Psychoanalysis," a lecture series given at Fordham University in 1912. Two later papers-"Freud and Jung: Contrasts" and the introduction to a book by W. M. Kranefeldt-together form a basis for further study of Jung's reassessment of psychoanalysis.Originally published in 1976.The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Psychoanalysis. --- Freud, Sigmund, --- Abreaction. --- Adoption. --- Analytical psychology. --- Anterograde amnesia. --- Antipathy. --- Antithesis. --- Anxiety disorder. --- Anxiety. --- Asceticism. --- Castration anxiety. --- Catharsis. --- Cherry picking. --- Consciousness. --- Cowardice. --- Criticism. --- Cynicism (contemporary). --- Delusion. --- Dementia praecox. --- Dementia. --- Depth psychology. --- Dissociation (psychology). --- Dream world (plot device). --- Eduard von Hartmann. --- Electra complex. --- Embarrassment. --- Extraversion and introversion. --- Family Constellations. --- Form of life (philosophy). --- Free association (psychology). --- General knowledge. --- Hostility. --- Hypnoid state. --- Hypnosis. --- Hypocrisy. --- Hysteria. --- Imbecile. --- Incest taboo. --- Incest. --- Indication (medicine). --- Introduction to Psychoanalysis. --- Laziness. --- Libido. --- Luck. --- Malthusianism. --- Masturbation. --- Modern physics. --- Narcissistic personality disorder. --- Negative transference. --- Neurosis. --- Neuroticism. --- Oedipus complex. --- Opportunism. --- Oppression. --- Overreaction. --- Pain and pleasure. --- Parapsychology. --- Pathological (mathematics). --- Perversion. --- Phenomenon. --- Pierre Janet. --- Precognition. --- Prejudice. --- Problem play. --- Psychiatry. --- Psychoanalysis. --- Psychoanalytic theory. --- Psychological repression. --- Psychological trauma. --- Psychology. --- Psychotherapy. --- Puberty. --- Rational emotive behavior therapy. --- Reaction formation. --- Reality principle. --- Religion. --- Scholasticism. --- Selfishness. --- Sexual dysfunction. --- Sexual fantasy. --- Sexual function. --- Sexual obsessions. --- Sexual repression. --- Sigmund Freud. --- Sin of omission. --- Sublimation (psychology). --- Suggestibility. --- Suggestion. --- Superstition. --- Symbols of Transformation. --- Symptom. --- The Future of an Illusion. --- The Interpretation of Dreams. --- The Philosopher. --- The Psychopathology of Everyday Life. --- Theory. --- Therapeutic effect. --- Thought. --- Totem and Taboo. --- Transference. --- Working hypothesis.