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Function and specificity of y/ơ T cells : international workshop, Schloss Elmau, Bavaria, FRG October 14-16, 1990
Authors: --- --- ---
ISBN: 3540537813 0387537813 9783540537816 9780387537818 3642764940 3642764924 Year: 1991 Volume: 173 Publisher: Berlin : Springer,

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Positronen Emissie Tomografie in België
Authors: --- --- --- --- --- et al.
Year: 2005 Publisher: Brussels KCE = Federaal Kenniscentrum voor de Gezondheidszorg = Centre Fédéral d'Expertise des Soins de Santé = Belgian Health Care Knowledge Centre


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Gas chromatographic/mass spectrometric differentiation of atenolol, metoprolol, propranolol, and an interfering metabolite product of metoprolol : final report
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Year: 2004 Publisher: Washington, DC : Springfield, Va. : Office of Aerospace Medicine, U.S. Dept. of Transportation, Federal Aviation Administration ; National Technical Information Service [distributor],

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Pilots who are considered hypertensive are closely monitored by the Federal Aviation Administration (FAA) to ensure that their hypertension is properly controlled. During the investigation of fatal civil aviation accidents, postmortem samples obtained from pilots are submitted to the FAA's Civil Aerospace Medical Institute (CAMI) for toxicological evaluation. During such evaluation, submitted samples are analyzed for prescription and nonprescription drugs, and it is common to find beta-blocker antihypertensives such as atenolol, metoprolol, and propranolol in the submitted biological samples. During a 10-year period of 1993-2002, postmortem samples from 3290 civil aviation accident pilot fatalities (cases) were received by CAMI. Toxicological evaluation of these cases revealed that 50 of the 3290 fatalities had the commonly prescribed beta-blockers, atenolol, metoprolol, and propranolol. Out of the 50 fatalities, atenolol, metoprolol, and propranolol were found to be present in 24, 19, and 7 fatalities, respectively, but the initial analysis indicated the presence of atenolol and metoprolol in 4 of these pilot fatalities. Since (i) the combined use of both drugs was not consistent with the history of the drug use by those pilots, (ii) it is uncommon to simultaneously prescribe 2 beta-blockers, and (iii) these commonly used antihypertensives have considerable amount of chemical and structural similarity (6), further examination was undertaken for those fatality cases wherein atenolol and metoprolol were initially detected. Such examination entailed selectively and simultaneously analyzing the 3 commonly used beta-blockers in the submitted biological samples and rectifying any possible analytical interference with the antihypertensives.


Book
Gas chromatographic/mass spectrometric differentiation of atenolol, metoprolol, propranolol, and an interfering metabolite product of metoprolol : final report
Authors: ---
Year: 2004 Publisher: Washington, DC : Springfield, Va. : Office of Aerospace Medicine, U.S. Dept. of Transportation, Federal Aviation Administration ; National Technical Information Service [distributor],

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Abstract

Pilots who are considered hypertensive are closely monitored by the Federal Aviation Administration (FAA) to ensure that their hypertension is properly controlled. During the investigation of fatal civil aviation accidents, postmortem samples obtained from pilots are submitted to the FAA's Civil Aerospace Medical Institute (CAMI) for toxicological evaluation. During such evaluation, submitted samples are analyzed for prescription and nonprescription drugs, and it is common to find beta-blocker antihypertensives such as atenolol, metoprolol, and propranolol in the submitted biological samples. During a 10-year period of 1993-2002, postmortem samples from 3290 civil aviation accident pilot fatalities (cases) were received by CAMI. Toxicological evaluation of these cases revealed that 50 of the 3290 fatalities had the commonly prescribed beta-blockers, atenolol, metoprolol, and propranolol. Out of the 50 fatalities, atenolol, metoprolol, and propranolol were found to be present in 24, 19, and 7 fatalities, respectively, but the initial analysis indicated the presence of atenolol and metoprolol in 4 of these pilot fatalities. Since (i) the combined use of both drugs was not consistent with the history of the drug use by those pilots, (ii) it is uncommon to simultaneously prescribe 2 beta-blockers, and (iii) these commonly used antihypertensives have considerable amount of chemical and structural similarity (6), further examination was undertaken for those fatality cases wherein atenolol and metoprolol were initially detected. Such examination entailed selectively and simultaneously analyzing the 3 commonly used beta-blockers in the submitted biological samples and rectifying any possible analytical interference with the antihypertensives.


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Sternberg's Diagnostic surgical pathology
Authors: --- --- --- ---
ISBN: 9781451188752 149630828X 1451188757 Year: 2015 Publisher: Philadelphia Wolters Kluwer

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"Sternberg's Diagnostic Surgical Pathology is the flagship book on LWW's pathology list. This classic 2-volume reference presents advanced diagnostic techniques and the latest information on all currently known diseases. The book emphasizes the practical differential diagnosis of the surgical specimen while keeping to a minimum discussion of the natural history of the disease, treatment and autopsy findings. Contributors are asked to provide their expert advice on the diagnostic evaluation of every type of specimen from every anatomic site. This approach distinguishes it from its key competition and provides a style of a personal consultation"--Provided by publisher.


Book
Lateral flow immunoassay
Authors: ---
ISBN: 1597452408 1617378380 9786611954819 1588299082 1281954810 Year: 2009 Publisher: New York : Springer,

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Due to the simplicity, relative accuracy, fast result reporting, and user-friendliness of lateral flow immunoassay, its use has undergone tremendous growth in the diagnostic industry in the last few years. Such technology has been utilized widely and includes: pregnancy and woman's health determination, cardiac and emergency conditions monitoring and testing, infectious disease including Flu screening, cancer marker screening, and drugs abuse testing. Lateral Flow Immunoassay covers the scope of utilization, the principle of the technology, the patent concerns, information on the development and production of the test device and specific applications will be of interest to the diagnostic industry and the gereal scientific community.


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Advanced Techniques in Diagnostic Microbiology : Volume 2: Applications
Authors: ---
ISBN: 3319951114 3319951106 Year: 2018 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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In recent years, advanced molecular techniques in diagnostic microbiology have been revolutionizing the practice of clinical microbiology in the hospital setting. Molecular diagnostic testing in general and nucleic acid-based amplification methods in particular have been heralded as diagnostic tools for the new millennium. This third edition covers not only the most recent updates and advances, but details newly invented omic techniques, such as next generation sequencing. It is divided into two distinct volumes, with Volume 1 describing the techniques, and Volume 2 addressing their applications in the field. In addition, both volumes focus more so on the clinical relevance of the test results generated by these techniques than previous editions. .

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