Narrow your search

Library

KU Leuven (485)

UGent (327)

ULB (276)

ULiège (275)

Odisee (270)

Thomas More Kempen (270)

Thomas More Mechelen (270)

UCLL (270)

VIVES (270)

VDIC (227)

More...

Resource type

book (499)

periodical (2)

digital (1)


Language

English (499)

German (2)


Year
From To Submit

2023 (1)

2021 (9)

2020 (21)

2019 (60)

2018 (39)

More...
Listing 1 - 10 of 501 << page
of 51
>>
Sort by

Book
Der Experimentator: Proteinbiochemie/Proteomics
Authors: ---
ISBN: 3662488515 Year: 2016 Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer Spektrum,

Loading...
Export citation

Choose an application

Bookmark

Abstract

Lieber EXPERIMENTATOR, die überarbeitete und aktualisierte 7. Auflage dieses Buches gibt Ihnen einen Überblick über die Methoden der Proteinbiochemie und Proteomics. Das Buch ist jedoch mehr als eine Methodensammlung: Es zeigt Auswege aus experimentellen und strategischen Sackgassen und weckt ein Gespür für das richtige Experiment zur richtigen Zeit. Behandelt werden klassische Verfahren wie Säulenchromatographie, HPLC, Elektrophoresen, Blots, ELISA, Ligandenbindungstests, die Herstellung von Antikörpern, das Solubilisieren von Membranproteinen, die Analyse von Glykoproteinen usw. Über die Standardverfahren hinaus beschreibt das Buch ausgefallene Methoden, mit denen sich spezielle Probleme lösen lassen: Wer arbeitet wie alle anderen, der wird sich nie vom großen Haufen abheben. Viel Raum nehmen auch die modernen Verfahren ein: Massenspektrometrie, Proteomics und thermische Analyse. In die 7. Auflage wurden neue Techniken zur Bestimmung der Wechselwirkung von Proteinen mit Proteinen oder von Proteinen mit kleinen Molekülen aufgenommen: DARTS, DRACALA, SPROX und andere. Sie können hier auch nachlesen, wie man mit dem Massenspektrometer eine Bindung misst und die Primärsequenz von Peptiden bestimmt. Des Weiteren stellen wir Methoden vor, mit denen Sie Bindungsproteine gegen bestimmte Zielmoleküle herstellen können: Ribosomen Display und DNA- und Peptid-Aptamer-Techniken. Der Fluoreszenznachweis von Proteinen mit Hilfe von Trihalogenverbindungen durfte nicht fehlen und wer die Stabilität und Faltung von Proteinen messen will, erfährt hier, ob er dazu ein CD-Spektrometer benutzen sollte. Auf die Fortschritte in der HPLC und der Massenspektrometrie von Membranproteinen geht die 7. Auflage ebenso ein wie auf ihre Rekonstitution in Nanoscheibchen (Nanodiscs). Die Mikrodissektion mit UV-Laser, die isoelektrische Fokussierung in Kapillaren und iTRAQ-Tags werden erklärt. Dazu kommt eine Anzahl neuer Tricks zur Proteinbestimmung, Gelfärbung, Blottechnik, Immunfärbung, Elution aus Gelstückchen etc. Es wird Ihnen auffallen, dass die Autoren Lust und Frust der Laborroutine kennen. Die eingestreuten Don Quichotte-Sprüche und der lockere Stil werden Ihnen über die Tiefpunkte des manchmal rauen Forscheralltags hinweghelfen.


Book
Multiheme Cytochromes
Authors: ---
Year: 2016 Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer,

Loading...
Export citation

Choose an application

Bookmark

Abstract

This brief introduces the structural and functional characterization of this important group of proteins. The content of each chapter is aimed at the non-specialist so that key concepts, methodologies and applications can be presented in a "snapshot" style volume. Multiheme cytochromes are ever more important now that it is possible to obtain genome sequences of microorganisms which have major biotechnological and environmental implications. There is a tremendous profusion of multiheme cytochromes which have great potential as targets for bioremediation and bioenergy applications. This brief gives a glimpse of an intriguing and fast-moving field. .


Book
Chemical Profiles of Industrial Cow’s Milk Curds
Authors: --- --- --- ---
Year: 2017 Publisher: Cham : Springer International Publishing : Imprint: Springer,

Loading...
Export citation

Choose an application

Bookmark

Abstract

This Brief explores the chemistry and production technology of a cheese precursor: the cow’s milk curd. It explains how different coagulation and treatment methods can be used to obtain various types of cheeses. Parameters such as the type of used milk, the coagulation method, pH value, color, and microbial fermentation have a profound impact on the resulting curd properties, and hence on the cheese. The authors discuss some of the most important parameters, and how their modification can lead to a variety of cheese and dairy products. This Brief also addresses the question, if cheese makers can standardize their production procedures, and what role chemistry may play in that. Another important point addressed here are the sources of failures in the curd production, e.g. in packaging systems. Readers will find selected examples of helpful analytical techniques for studying and evaluating curd quality, and for monitoring the chemical evolution of selected chemical substances or protein aggregation. .


Book
Multiheme Cytochromes
Authors: ---
Year: 2016 Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer,

Loading...
Export citation

Choose an application

Bookmark

Abstract

This brief introduces the structural and functional characterization of this important group of proteins. The content of each chapter is aimed at the non-specialist so that key concepts, methodologies and applications can be presented in a "snapshot" style volume. Multiheme cytochromes are ever more important now that it is possible to obtain genome sequences of microorganisms which have major biotechnological and environmental implications. There is a tremendous profusion of multiheme cytochromes which have great potential as targets for bioremediation and bioenergy applications. This brief gives a glimpse of an intriguing and fast-moving field. .


Book
Chemical Profiles of Industrial Cow’s Milk Curds
Authors: --- --- --- ---
Year: 2017 Publisher: Cham : Springer International Publishing : Imprint: Springer,

Loading...
Export citation

Choose an application

Bookmark

Abstract

This Brief explores the chemistry and production technology of a cheese precursor: the cow’s milk curd. It explains how different coagulation and treatment methods can be used to obtain various types of cheeses. Parameters such as the type of used milk, the coagulation method, pH value, color, and microbial fermentation have a profound impact on the resulting curd properties, and hence on the cheese. The authors discuss some of the most important parameters, and how their modification can lead to a variety of cheese and dairy products. This Brief also addresses the question, if cheese makers can standardize their production procedures, and what role chemistry may play in that. Another important point addressed here are the sources of failures in the curd production, e.g. in packaging systems. Readers will find selected examples of helpful analytical techniques for studying and evaluating curd quality, and for monitoring the chemical evolution of selected chemical substances or protein aggregation. .


Book
Multiheme Cytochromes
Authors: ---
Year: 2016 Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer,

Loading...
Export citation

Choose an application

Bookmark

Abstract

This brief introduces the structural and functional characterization of this important group of proteins. The content of each chapter is aimed at the non-specialist so that key concepts, methodologies and applications can be presented in a "snapshot" style volume. Multiheme cytochromes are ever more important now that it is possible to obtain genome sequences of microorganisms which have major biotechnological and environmental implications. There is a tremendous profusion of multiheme cytochromes which have great potential as targets for bioremediation and bioenergy applications. This brief gives a glimpse of an intriguing and fast-moving field. .


Book
Chemical Profiles of Industrial Cow’s Milk Curds
Authors: --- --- --- ---
Year: 2017 Publisher: Cham : Springer International Publishing : Imprint: Springer,

Loading...
Export citation

Choose an application

Bookmark

Abstract

This Brief explores the chemistry and production technology of a cheese precursor: the cow’s milk curd. It explains how different coagulation and treatment methods can be used to obtain various types of cheeses. Parameters such as the type of used milk, the coagulation method, pH value, color, and microbial fermentation have a profound impact on the resulting curd properties, and hence on the cheese. The authors discuss some of the most important parameters, and how their modification can lead to a variety of cheese and dairy products. This Brief also addresses the question, if cheese makers can standardize their production procedures, and what role chemistry may play in that. Another important point addressed here are the sources of failures in the curd production, e.g. in packaging systems. Readers will find selected examples of helpful analytical techniques for studying and evaluating curd quality, and for monitoring the chemical evolution of selected chemical substances or protein aggregation. .


Book
Heat Shock Protein 90 in Human Diseases and Disorders
Authors: ---
ISBN: 3030231585 3030231577 Year: 2019 Publisher: Cham : Springer International Publishing : Imprint: Springer,

Loading...
Export citation

Choose an application

Bookmark

Abstract

The book Heat Shock Protein 90 in Human Diseases and Disorders provides the most comprehensive review on contemporary knowledge on the role of HSP90. Using an integrative approach, the contributors provide a synopsis of novel mechanisms, previously unknown signal transduction pathways. To enhance the ease of reading and comprehension, this book has been subdivided into various section including; Section I, reviews current progress on our understanding Oncogenic Aspects of HSP90; Section II, focuses on Bimolecular Aspects of HSP90; Section III, emphasizes and HSP90 in Natural Products Development and Section IV; give the most up to date reviews on Clinical Aspects of HSP90. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Translational Medicine, Clinical Research, Human Physiology, Biotechnology, Natural Products, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.


Book
Alterungsprozesse und Neurodegeneration : Ein Überblick
Author:
ISBN: 3658056142 9783658056148 Year: 2014 Publisher: Wiesbaden : Springer Fachmedien Wiesbaden : Imprint: Springer Spektrum,

Loading...
Export citation

Choose an application

Bookmark

Abstract

Das Essential behandelt in leicht verständlicher, komprimierter Weise die Grundlagen altersbedingter Zellveränderungen, die unter Umständen zur Neurodegeneration führen können. Der Autor erläutert, wie der Alterungsprozess und die Neurodegeneration durch oxidativen Stress und dabei entstehende Schäden beeinflusst werden. Unter diesen Schäden nimmt die Bildung von Proteinaggregaten, die hier besonders ausführlich beschrieben werden, eine Schlüsselstellung ein. Darüber hinaus werden einige Aspekte der Ernährung im Alter und ihre möglichen Auswirkungen auf die Entstehung von neurodegenerativen Erkrankungen vorgestellt. Der Inhalt Aspekte und Biologie des Alterns Oxidativer Stress während der Alterung Gehirn und Neurodegeneration Proteinaggregate in Neurodegeneration und Alterung Ernährung und Alter – Prävention von Neurodegeneration? Die Zielgruppen Dozierende und Studierende in den Bereichen Medizin, Ernährungswissenschaften, Pharmazie, Lebensmittelchemie und -technologie, Biologie, Biochemie, Biophysik und ähnlicher Fächer Ernährungsberater/-innen, Apotheker/-innen, Ärzte und Ärztinnen sowie andere im Gesundheitswesen beschäftigte Personen Der Autor Prof. Dr. Tilman Grune ist Direktor des Instituts für Ernährungswissenschaften sowie Inhaber des Lehrstuhls für Ernährungstoxikologie der Friedrich-Schiller-Universität Jena.


Book
Heat Shock Proteins and Plants
Authors: --- ---
Year: 2016 Publisher: Cham : Springer International Publishing : Imprint: Springer,

Loading...
Export citation

Choose an application

Bookmark

Abstract

Heat Shock Proteins and Plants provides the most up-to-date and concise reviews and progress on the role of heat shock proteins in plant biology, structure and function and is subdivided into chapters focused on Small Plant HSPs (Part I), Larger Plant HSPs (Part II) and HSPs for Therapeutic Gain (Part III). This book is written by eminent leaders and experts from around the world and is an important reference book and a must-read for undergraduate, postgraduate students and researchers in the fields of Agriculture, Botany, Crop Research, Plant Genetics and Biochemistry, Biotechnology, Drug Development and Pharmaceutical Sciences.

Listing 1 - 10 of 501 << page
of 51
>>
Sort by