Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Food processing by humans goes a long way back in time, e.g., heat for cooking was used 1.9 million years ago. However, meal preparation now seems to be moving out of the home kitchen, and preprocessed or processed/convenience food products are becoming a larger part of the daily diet. In addition, consumers are progressively focusing on the impact of food on their health, and they demand foods that have a high nutritional quality and an aroma and natural flavor that are similar to freshly-made products. Therefore, nutritional quality is concurrent with food safety, and sensory perception is becoming an increasingly important factor in food choices. The human digestive tract disintegrates food to allow the nutrients to be released and made available to the body. However, nutrients can undergo unwanted degradation upon processing and subsequent storage, negatively influencing the physiological effects. Different processing techniques will result in different food structures, thereby also affecting bioaccessibility and nutritional value. Hence, food scientists and industry have an increased interest in both conventional and innovative processing methods that can provide good-quality products with high nutritional value and stable shelf life. This Special Issue aims to shed some light on the latest knowledge about and developments within the effects of food processing and storage on changes of biochemical and nutritional compounds. Both original research articles and reviews are included in this book.

History of engineering & technology --- protein fractionation --- white teff --- brown teff --- amino acid profile --- seed storage proteins --- essential amino acids --- anthocyanins --- ascorbic acid --- UV-Vis --- HPLC-MS --- kinetics --- shelf life --- legume protein --- processing --- digestibility --- PEF --- OH --- POD --- colour --- extraction --- spray drying --- freeze drying --- antioxidants --- carotenoid aggregates --- coloring foods --- grouper --- refrigerated storage --- packaging methods --- protein oxidation --- protein degradation --- n/a

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Medicinal plants or medicinal herbs have been identified and used since ancient times to improve the sensory characteristics of food. The main compounds found in plants correspond to four major biochemical classes: Polyphenols, terpenes, glycosides and alkaloids. Plants synthesize these compounds for a variety of purposes, including protection of the plant against fungi and bacteria, defense against insects and attraction of pollinators and dispersal agents to favor the dispersion of seeds and pollens.

Research & information: general --- Biology, life sciences --- Food & society --- anti-obesity --- anti-lipase --- traditional medicine --- folkloric food --- Acetaminophen --- Vernonia calvoana --- serum lipid indices --- hypolipidemic activity and antioxidants --- flavonoids --- diabetes --- Rosaceae --- Mespilus germanica --- mice --- brine-injected pork --- green tea extract --- maté extract --- ascorbate --- protein oxidation --- sensory quality --- high-oxygen modified atmosphere packaging --- brine injection --- pork --- lipid oxidation --- modified atmosphere packaging --- hydroxytyrosol --- antioxidant --- antimicrobial --- meat --- preservative --- health --- antioxidants --- Lamiaceae --- polyphenols --- Stachys mucronata --- Capnophyllum peregrinum --- antioxidant activity --- photoprotective activity --- macroalgae --- microalgae --- extraction yield --- total phenolic content --- Euphorbia dendroides --- phenolic compounds --- HPLC --- antiproliferative activity --- Caco-2 cells --- iron --- bioavailability --- phytic acid --- agro by-products --- food waste --- waste utilization --- anti-inflammatory --- medicinal plants --- chronic diseases --- Uncaria tomentosa --- Harpagophytum procumbens --- Myrciaria dubia --- Ribes nigrum --- hesperidin --- rosemary --- anti-obesity --- anti-lipase --- traditional medicine --- folkloric food --- Acetaminophen --- Vernonia calvoana --- serum lipid indices --- hypolipidemic activity and antioxidants --- flavonoids --- diabetes --- Rosaceae --- Mespilus germanica --- mice --- brine-injected pork --- green tea extract --- maté extract --- ascorbate --- protein oxidation --- sensory quality --- high-oxygen modified atmosphere packaging --- brine injection --- pork --- lipid oxidation --- modified atmosphere packaging --- hydroxytyrosol --- antioxidant --- antimicrobial --- meat --- preservative --- health --- antioxidants --- Lamiaceae --- polyphenols --- Stachys mucronata --- Capnophyllum peregrinum --- antioxidant activity --- photoprotective activity --- macroalgae --- microalgae --- extraction yield --- total phenolic content --- Euphorbia dendroides --- phenolic compounds --- HPLC --- antiproliferative activity --- Caco-2 cells --- iron --- bioavailability --- phytic acid --- agro by-products --- food waste --- waste utilization --- anti-inflammatory --- medicinal plants --- chronic diseases --- Uncaria tomentosa --- Harpagophytum procumbens --- Myrciaria dubia --- Ribes nigrum --- hesperidin --- rosemary

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Alveolar epithelial cells (AECs) of the lung are important contributors to pulmonary immune functions and to pulmonary development and alveolar repair mechanisms following lung injury. AECI, together with the capillary endothelium, form the extremely thin barrier between alveolar air and blood. AECII produce and metabolize the surface-tension lowering and immune-modulating surfactant and are the progentiors of AECI. A great variety of processes rely on their normal functioning, including maintenance of the alveolar barrier; innate immune defense; and processes of differentiation, senescence, apoptosis, and autophagy. The wide range of AEC functions is nicely reflected by the diversity of topics addressed by the four review and eight original articles contained in this Special Issue of the International Journal of Molecular Sciences. Beyond the broad spectrum of topics, the authors of this issue also made use of an impressive variety of analytical methods, thus further illustrating the fascinating diversity of aspects related to AEC biology.

Research & information: general --- Biology, life sciences --- JAM-A --- P2X7 receptor --- mouse lung --- alveolar epithelium --- bleomycin-induced lung injury --- GSK-3β --- dietary sugar --- hyperglycemia --- lung mechanics --- alveolar septal composition --- physical activity --- extracellular matrix remodeling --- high-altitude pulmonary edema --- acute mountain sickness --- oxygen diffusion limitation --- surfactant protein B --- atelectrauma --- alveolar fluid --- acinar micromechanics --- acute lung injury --- autophagy --- lysosome --- lysosomal membrane permeability --- mitochondria --- pneumocyte --- microRNA-21 --- alveolar micromechanics --- structural remodeling --- inflammatory signaling --- lung --- alveolus --- type 1 alveolar epithelial cell --- type 2 alveolar epithelial cell --- focused ion beam scanning electron microscopy --- 3D reconstruction --- carbon dioxide --- hypercapnia --- Na,K-ATPase --- endoplasmic reticulum --- sodium transport --- protein oxidation --- alveolar epithelial cells --- pulmonary fibrosis --- epithelial cell dysfunction --- stem cell exhaustion --- pneumonia --- necrotizing --- regeneration --- model --- bovine --- chlamydia --- alveoli --- air-blood barrier --- epithelium --- air-liquid interface --- alveolar lining layer --- glycocalyx --- surfactant --- lung injury --- lung regeneration

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Alveolar epithelial cells (AECs) of the lung are important contributors to pulmonary immune functions and to pulmonary development and alveolar repair mechanisms following lung injury. AECI, together with the capillary endothelium, form the extremely thin barrier between alveolar air and blood. AECII produce and metabolize the surface-tension lowering and immune-modulating surfactant and are the progentiors of AECI. A great variety of processes rely on their normal functioning, including maintenance of the alveolar barrier; innate immune defense; and processes of differentiation, senescence, apoptosis, and autophagy. The wide range of AEC functions is nicely reflected by the diversity of topics addressed by the four review and eight original articles contained in this Special Issue of the International Journal of Molecular Sciences. Beyond the broad spectrum of topics, the authors of this issue also made use of an impressive variety of analytical methods, thus further illustrating the fascinating diversity of aspects related to AEC biology.

JAM-A --- P2X7 receptor --- mouse lung --- alveolar epithelium --- bleomycin-induced lung injury --- GSK-3β --- dietary sugar --- hyperglycemia --- lung mechanics --- alveolar septal composition --- physical activity --- extracellular matrix remodeling --- high-altitude pulmonary edema --- acute mountain sickness --- oxygen diffusion limitation --- surfactant protein B --- atelectrauma --- alveolar fluid --- acinar micromechanics --- acute lung injury --- autophagy --- lysosome --- lysosomal membrane permeability --- mitochondria --- pneumocyte --- microRNA-21 --- alveolar micromechanics --- structural remodeling --- inflammatory signaling --- lung --- alveolus --- type 1 alveolar epithelial cell --- type 2 alveolar epithelial cell --- focused ion beam scanning electron microscopy --- 3D reconstruction --- carbon dioxide --- hypercapnia --- Na,K-ATPase --- endoplasmic reticulum --- sodium transport --- protein oxidation --- alveolar epithelial cells --- pulmonary fibrosis --- epithelial cell dysfunction --- stem cell exhaustion --- pneumonia --- necrotizing --- regeneration --- model --- bovine --- chlamydia --- alveoli --- air-blood barrier --- epithelium --- air-liquid interface --- alveolar lining layer --- glycocalyx --- surfactant --- lung injury --- lung regeneration

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The high importance of free radical chemistry for a variety of biological events, including ageing and inflammation, has attracted considerable interest in understanding the related mechanistic steps at the molecular level. Modelling the free radical chemical reactivity of biological systems is an important research area. When studying free-radical-based chemical mechanisms, biomimetic chemistry and the design of established biomimetic models come into play to perform experiments in a controlled environment, suitably designed to be a similar as possible to cellular conditions. This Special Issue provides readers with a wide overview of biomimetic radical chemistry, where molecular mechanisms have been defined and molecular libraries of products are developed to be used as traces for the discoveries of some relevant biological processes. Several subjects are presented, with five articles and five reviews written by specialists in the fields of DNA, proteins, lipids, biotechnological applications and bioinspired synthesis, with “free radicals” as the common denominator.

Research & information: general --- Chemistry --- Inorganic chemistry --- guanine --- guanyl radical --- tautomerism --- guanine radical cation --- oligonucleotides --- DNA --- G-quadruplex --- time-resolved spectroscopies --- reactive oxygen species (ROS) --- oxidation --- catalase mimics --- peroxide --- diiron-peroxo complexes --- structure/activity --- kinetic studies --- biomimetic chemistry --- cysteine --- ketone reduction --- free radicals --- pulse radiolysis --- kinetics --- DNA oxidation --- DNA hole transfer --- molecular dynamics --- quantum dynamics --- electron transfer --- charge transfer --- quantum coherence --- chemiluminescence --- reaction mechanisms --- singlet oxygen --- reactive oxygen species --- light emission --- crosslink --- dimerization --- protein oxidation --- radicals --- di-tyrosine --- di-tryptophan --- disulfides --- thiols --- aggregation --- proteomics --- mass spectrometry --- collagen --- riboflavin --- hyaluronic acid --- EPR spectroscopy --- keratoconus --- STEM --- DNA biosensor --- chemical nucleases --- DNA-drug interaction --- copper complexes --- metallodrugs --- MEP pathway --- antibiotics --- IspH --- LytB --- [4Fe-4S] cluster --- reductive dehydroxylation --- bioorganometallic intermediate --- inhibitors --- methionine --- neighboring group effect --- hydroxyl radical --- triplet state of carboxybenzophenone --- one-electron oxidants --- laser flash photolysis --- peptides --- proteins --- guanine --- guanyl radical --- tautomerism --- guanine radical cation --- oligonucleotides --- DNA --- G-quadruplex --- time-resolved spectroscopies --- reactive oxygen species (ROS) --- oxidation --- catalase mimics --- peroxide --- diiron-peroxo complexes --- structure/activity --- kinetic studies --- biomimetic chemistry --- cysteine --- ketone reduction --- free radicals --- pulse radiolysis --- kinetics --- DNA oxidation --- DNA hole transfer --- molecular dynamics --- quantum dynamics --- electron transfer --- charge transfer --- quantum coherence --- chemiluminescence --- reaction mechanisms --- singlet oxygen --- reactive oxygen species --- light emission --- crosslink --- dimerization --- protein oxidation --- radicals --- di-tyrosine --- di-tryptophan --- disulfides --- thiols --- aggregation --- proteomics --- mass spectrometry --- collagen --- riboflavin --- hyaluronic acid --- EPR spectroscopy --- keratoconus --- STEM --- DNA biosensor --- chemical nucleases --- DNA-drug interaction --- copper complexes --- metallodrugs --- MEP pathway --- antibiotics --- IspH --- LytB --- [4Fe-4S] cluster --- reductive dehydroxylation --- bioorganometallic intermediate --- inhibitors --- methionine --- neighboring group effect --- hydroxyl radical --- triplet state of carboxybenzophenone --- one-electron oxidants --- laser flash photolysis --- peptides --- proteins