Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Over the last few decades, the study of microbial biofilms has been gaining interest among the scientific community. These microbial communities comprise cells adhered to surfaces that are surrounded by a self-produced exopolymeric matrix that protects biofilm cells against different external stresses. Biofilms can have a negative impact on different sectors within society, namely in agriculture, food industries, and veterinary and human health. As a consequence of their metabolic state and matrix protection, biofilm cells are very difficult to tackle with antibiotics or chemical disinfectants. Due to this problem, recent advances in the development of antibiotic alternatives or complementary strategies to prevent or control biofilms have been reported. This book includes different strategies to prevent biofilm formation or to control biofilm development and includes full research articles, reviews, a communication, and a perspective.

antibiofilm --- antimicrobial agent --- bacteria --- fungi --- polymicrobial biofilm --- microalga --- free fatty acids --- encapsulation --- biofilm --- chronic wounds --- host response --- S100A8/A9 --- dental plaque --- quorum sensing --- microbial resistance --- bacterial adhesion --- blocking effect --- hydrodynamics --- parallel plate flow cell --- carbon nanotubes --- poly(dimethylsiloxane) --- adhesion --- Escherichia coli --- Biofilm --- Public Engagement --- Outreach --- Control Strategies --- Oral Biofilm --- TiO2 nanofibers --- electrospinning --- biofilm prevention and control --- multidrug-resistant bacteria --- biomedical application --- biofilms --- biofilm inhibition --- dental implants --- peri-implantitis --- polyether-ether-ketone --- Pseudomonas aeruginosa --- Candida albicans --- mixed-species biofilm analysis --- flow cytometry --- bacteriophage therapy --- prosthesis related infections --- hardware infections --- left ventricular assist devices --- Acinetobacter baumannii --- antibiotic resistance --- antibiotic tolerance --- persister --- intraspecies community --- EPS matrix --- peptide nucleic acid-fluorescence in situ hybridization --- urinary tract infections --- catheter-associated urinary tract infections --- confocal laser scanning microscopy --- recalcitrance --- biofilm control --- Klebsiella pneumoniae --- KPC and OXA-48-like carbapenemases --- Galleria mellonella infection model --- linear oligoethyleneimine hydrochloride --- bacteriophage --- endotracheal tube --- n/a

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

In the past, osseointegration was regarded to be a mode of implant anchorage that simulated a simple wound healing phenomenon. Today, we have evidence that osseointegration is, in fact, a foreign body reaction that involves an immunologically derived bony demarcation of an implant to shield it off from the tissues. Marginal bone resorption around an oral implant cannot be properly understood without realizing the foreign body nature of the implant itself. Whereas the immunological response as such is positive for implant longevity, adverse immunological reactions may cause marginal bone loss in combination with combined factors. Combined factors include the hardware, clinical handling as well as patient characteristics that, even if each one of these factors only produce subliminal trauma, when acting together they may result in loss of marginal bone. The role of bacteria in the process of marginal bone loss is smaller than previously believed due to combined defense mechanisms of inflammation and immunological reactions, but if the defense is failing we may see bacterially induced marginal bone loss as well. However, problems with loss of marginal bone threatening implant survival remains relatively uncommon; we have today 10 years of clinical documentation of five different types of implant displaying a failure rate in the range of only 1 to 4 %.

Medicine --- osseointegration --- dental implant --- peri-implantitis --- ligature-induced peri-implantitis --- aseptic loosening --- systematic review --- immune system --- biomaterials --- foreign body reaction --- in vivo study --- oral implants --- marginal bone loss --- immunomodulation --- mechanotransduction --- Crestal bone loss --- osseosufficiency --- osseoseparation --- photoacoustic ultrasound --- brain–bone axis --- overloading --- radiography --- CBCT (cone beam computerized tomography) --- osteogenesis --- osteotomy --- bone healing --- bone chips --- drilling tool design --- fused deposition modeling --- polyether ether ketone --- biocomposite --- orthopedic implant --- oral implant --- mechanical properties --- wettability --- topography --- biocompatibility --- cell adhesion --- peri-implant endosseous healing --- dental implantation --- alveolar bone loss --- alveolar bone remodeling/regeneration --- bone biology --- finite element analysis (FEA) --- biomechanics --- cell plasticity --- dental implants --- electron microscopy --- scanning transmission electron microscopy --- bone-implant interface --- bone loss --- overdenture --- implant survival --- implant surface --- soft tissue --- split-mouth design --- oral health-related quality of life --- patient-reported outcome measures --- biomaterial --- bone --- immune --- implant --- healing --- titanium --- PEEK --- Cu --- micro-RNA --- microarray --- predictive biomarker --- epigenomics --- mucositis --- diagnosis --- over-treatment --- iatrogenic damage --- abutment height --- subcrestal implants --- implant insertion depth --- vertical mucosal thickness --- biological width --- implant installation --- anchorage technique --- histology --- intraosseous temperature --- finite element model --- ligature induced peri-implantitis --- arthroplasty --- replacement --- hip --- hypersensitivity --- contact --- allergy and immunology --- cytokines --- Interleukin-8 --- surface properties --- materials testing --- implant contamination --- scanning electron microscopy --- energy-dispersive X-ray spectrometry --- convergence --- clinical study --- biofilm --- infection --- perio-prosthetic joint infection --- periimplantitis --- electrolytic cleaning --- n/a --- zirconia --- insertion --- bone–implant interface --- heat --- bone damage --- early loss --- augmentation --- air flow --- re-osseointegration --- classification of bone defects --- dog study --- brain-bone axis

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

In the past, osseointegration was regarded to be a mode of implant anchorage that simulated a simple wound healing phenomenon. Today, we have evidence that osseointegration is, in fact, a foreign body reaction that involves an immunologically derived bony demarcation of an implant to shield it off from the tissues. Marginal bone resorption around an oral implant cannot be properly understood without realizing the foreign body nature of the implant itself. Whereas the immunological response as such is positive for implant longevity, adverse immunological reactions may cause marginal bone loss in combination with combined factors. Combined factors include the hardware, clinical handling as well as patient characteristics that, even if each one of these factors only produce subliminal trauma, when acting together they may result in loss of marginal bone. The role of bacteria in the process of marginal bone loss is smaller than previously believed due to combined defense mechanisms of inflammation and immunological reactions, but if the defense is failing we may see bacterially induced marginal bone loss as well. However, problems with loss of marginal bone threatening implant survival remains relatively uncommon; we have today 10 years of clinical documentation of five different types of implant displaying a failure rate in the range of only 1 to 4 %.

Medicine --- osseointegration --- dental implant --- peri-implantitis --- ligature-induced peri-implantitis --- aseptic loosening --- systematic review --- immune system --- biomaterials --- foreign body reaction --- in vivo study --- oral implants --- marginal bone loss --- immunomodulation --- mechanotransduction --- Crestal bone loss --- osseosufficiency --- osseoseparation --- photoacoustic ultrasound --- brain-bone axis --- overloading --- radiography --- CBCT (cone beam computerized tomography) --- osteogenesis --- osteotomy --- bone healing --- bone chips --- drilling tool design --- fused deposition modeling --- polyether ether ketone --- biocomposite --- orthopedic implant --- oral implant --- mechanical properties --- wettability --- topography --- biocompatibility --- cell adhesion --- peri-implant endosseous healing --- dental implantation --- alveolar bone loss --- alveolar bone remodeling/regeneration --- bone biology --- finite element analysis (FEA) --- biomechanics --- cell plasticity --- dental implants --- electron microscopy --- scanning transmission electron microscopy --- bone-implant interface --- bone loss --- overdenture --- implant survival --- implant surface --- soft tissue --- split-mouth design --- oral health-related quality of life --- patient-reported outcome measures --- biomaterial --- bone --- immune --- implant --- healing --- titanium --- PEEK --- Cu --- micro-RNA --- microarray --- predictive biomarker --- epigenomics --- mucositis --- diagnosis --- over-treatment --- iatrogenic damage --- abutment height --- subcrestal implants --- implant insertion depth --- vertical mucosal thickness --- biological width --- implant installation --- anchorage technique --- histology --- intraosseous temperature --- finite element model --- ligature induced peri-implantitis --- arthroplasty --- replacement --- hip --- hypersensitivity --- contact --- allergy and immunology --- cytokines --- Interleukin-8 --- surface properties --- materials testing --- implant contamination --- scanning electron microscopy --- energy-dispersive X-ray spectrometry --- convergence --- clinical study --- biofilm --- infection --- perio-prosthetic joint infection --- periimplantitis --- electrolytic cleaning --- zirconia --- insertion --- bone-implant interface --- heat --- bone damage --- early loss --- augmentation --- air flow --- re-osseointegration --- classification of bone defects --- dog study --- osseointegration --- dental implant --- peri-implantitis --- ligature-induced peri-implantitis --- aseptic loosening --- systematic review --- immune system --- biomaterials --- foreign body reaction --- in vivo study --- oral implants --- marginal bone loss --- immunomodulation --- mechanotransduction --- Crestal bone loss --- osseosufficiency --- osseoseparation --- photoacoustic ultrasound --- brain-bone axis --- overloading --- radiography --- CBCT (cone beam computerized tomography) --- osteogenesis --- osteotomy --- bone healing --- bone chips --- drilling tool design --- fused deposition modeling --- polyether ether ketone --- biocomposite --- orthopedic implant --- oral implant --- mechanical properties --- wettability --- topography --- biocompatibility --- cell adhesion --- peri-implant endosseous healing --- dental implantation --- alveolar bone loss --- alveolar bone remodeling/regeneration --- bone biology --- finite element analysis (FEA) --- biomechanics --- cell plasticity --- dental implants --- electron microscopy --- scanning transmission electron microscopy --- bone-implant interface --- bone loss --- overdenture --- implant survival --- implant surface --- soft tissue --- split-mouth design --- oral health-related quality of life --- patient-reported outcome measures --- biomaterial --- bone --- immune --- implant --- healing --- titanium --- PEEK --- Cu --- micro-RNA --- microarray --- predictive biomarker --- epigenomics --- mucositis --- diagnosis --- over-treatment --- iatrogenic damage --- abutment height --- subcrestal implants --- implant insertion depth --- vertical mucosal thickness --- biological width --- implant installation --- anchorage technique --- histology --- intraosseous temperature --- finite element model --- ligature induced peri-implantitis --- arthroplasty --- replacement --- hip --- hypersensitivity --- contact --- allergy and immunology --- cytokines --- Interleukin-8 --- surface properties --- materials testing --- implant contamination --- scanning electron microscopy --- energy-dispersive X-ray spectrometry --- convergence --- clinical study --- biofilm --- infection --- perio-prosthetic joint infection --- periimplantitis --- electrolytic cleaning --- zirconia --- insertion --- bone-implant interface --- heat --- bone damage --- early loss --- augmentation --- air flow --- re-osseointegration --- classification of bone defects --- dog study