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Dear Colleagues,Supramolecular systems (calixarenes, cyclodextrins, polymers, peptides, etc.) have attracted special attention due to their excellent therapeutic properties for biomedical applications such as gene and drug delivery. Numerous biomaterials-based supramolecular systems have been developed in the last decade for enhancing of biocompatibility and pharmacological activity. In particular, supramolecular nanomaterials are considered a hot research topic, because nanomedicine has become an interesting tool for the treatment of genetic diseases or cancer. Nevertheless, novel systems and their properties are being continuously studied, contributing to the development of efficient delivery systems.This Special Issue provides and highlights current progress in the use of the supramolecular systems for boosting gene and drug delivery. Preparation, characterization, and use of these systems, as well as the latest developments in this research field, are especially welcome.Authors are encorauged to submit original research articles and reviews in this promising research field.

Research & information: general --- Chemistry --- β-cyclodextrin-based nanosponge --- phenylethylamine --- 2-amino-4-(4-chlorophenyl)thiazole (AT) --- gold nanoparticles --- carrier of therapeutic agents --- ferritin --- drug delivery --- tumor targeting --- half-life extension --- PAMAM dendrimers --- folic acid --- mRNA --- gene expression --- long acting injectables --- poly(l-lactic acid) --- poly(butylene adipate) --- block copolymers --- aripiprazole --- microparticles --- sustained release --- cationic calix[4]arenes --- liposomes --- nucleic acids --- transfection efficiency --- doxorubicin --- encapsulation --- adenine–uracil base pair --- complementary hydrogen bonded drug carrier system --- controlled drug delivery --- supramolecular nanogels --- selective cytotoxicity --- supramolecular self-assembled ribbon-like structures (SRLS) --- Congo red (CR) --- doxorubicin (Dox) --- bovine serum albumin (BSA) --- immunoglobulin light chain λ (Lλ) --- heat aggregated immunoglobulins (HAI) --- dynamic light scattering (DLS) --- elution volume (Ve) --- multi-walled carbon nanotube --- photothermal therapy --- indocyanine green --- synergistic strategy --- cancer treatment --- targeted drug delivery --- pillararene --- host:guest --- supramolecular --- hydrophobic --- ITC --- NMR --- magnetoliposomes --- microfluidics --- oral drug delivery --- magnetite nanoparticles --- n/a --- adenine-uracil base pair

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• Reference Manager
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Dear Colleagues,Supramolecular systems (calixarenes, cyclodextrins, polymers, peptides, etc.) have attracted special attention due to their excellent therapeutic properties for biomedical applications such as gene and drug delivery. Numerous biomaterials-based supramolecular systems have been developed in the last decade for enhancing of biocompatibility and pharmacological activity. In particular, supramolecular nanomaterials are considered a hot research topic, because nanomedicine has become an interesting tool for the treatment of genetic diseases or cancer. Nevertheless, novel systems and their properties are being continuously studied, contributing to the development of efficient delivery systems.This Special Issue provides and highlights current progress in the use of the supramolecular systems for boosting gene and drug delivery. Preparation, characterization, and use of these systems, as well as the latest developments in this research field, are especially welcome.Authors are encorauged to submit original research articles and reviews in this promising research field.

Research & information: general --- Chemistry --- β-cyclodextrin-based nanosponge --- phenylethylamine --- 2-amino-4-(4-chlorophenyl)thiazole (AT) --- gold nanoparticles --- carrier of therapeutic agents --- ferritin --- drug delivery --- tumor targeting --- half-life extension --- PAMAM dendrimers --- folic acid --- mRNA --- gene expression --- long acting injectables --- poly(l-lactic acid) --- poly(butylene adipate) --- block copolymers --- aripiprazole --- microparticles --- sustained release --- cationic calix[4]arenes --- liposomes --- nucleic acids --- transfection efficiency --- doxorubicin --- encapsulation --- adenine-uracil base pair --- complementary hydrogen bonded drug carrier system --- controlled drug delivery --- supramolecular nanogels --- selective cytotoxicity --- supramolecular self-assembled ribbon-like structures (SRLS) --- Congo red (CR) --- doxorubicin (Dox) --- bovine serum albumin (BSA) --- immunoglobulin light chain λ (Lλ) --- heat aggregated immunoglobulins (HAI) --- dynamic light scattering (DLS) --- elution volume (Ve) --- multi-walled carbon nanotube --- photothermal therapy --- indocyanine green --- synergistic strategy --- cancer treatment --- targeted drug delivery --- pillararene --- host:guest --- supramolecular --- hydrophobic --- ITC --- NMR --- magnetoliposomes --- microfluidics --- oral drug delivery --- magnetite nanoparticles --- β-cyclodextrin-based nanosponge --- phenylethylamine --- 2-amino-4-(4-chlorophenyl)thiazole (AT) --- gold nanoparticles --- carrier of therapeutic agents --- ferritin --- drug delivery --- tumor targeting --- half-life extension --- PAMAM dendrimers --- folic acid --- mRNA --- gene expression --- long acting injectables --- poly(l-lactic acid) --- poly(butylene adipate) --- block copolymers --- aripiprazole --- microparticles --- sustained release --- cationic calix[4]arenes --- liposomes --- nucleic acids --- transfection efficiency --- doxorubicin --- encapsulation --- adenine-uracil base pair --- complementary hydrogen bonded drug carrier system --- controlled drug delivery --- supramolecular nanogels --- selective cytotoxicity --- supramolecular self-assembled ribbon-like structures (SRLS) --- Congo red (CR) --- doxorubicin (Dox) --- bovine serum albumin (BSA) --- immunoglobulin light chain λ (Lλ) --- heat aggregated immunoglobulins (HAI) --- dynamic light scattering (DLS) --- elution volume (Ve) --- multi-walled carbon nanotube --- photothermal therapy --- indocyanine green --- synergistic strategy --- cancer treatment --- targeted drug delivery --- pillararene --- host:guest --- supramolecular --- hydrophobic --- ITC --- NMR --- magnetoliposomes --- microfluidics --- oral drug delivery --- magnetite nanoparticles

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Polymers are the largest and most versatile class of biomaterials, being extensively applied for therapeutic applications. From natural to synthetic polymers, the possibilities to design and modify their physical-chemical properties make these systems of great interest in a wide range of biomedical applications as diverse as drug delivery systems, organ-on-a-chip, diagnostics, tissue engineering, and so on.In recent years, advances in the synthesis and modification of polymers and characterization techniques have allowed the design of novel biomaterials as well as the study of their biological behavior in vitro and in vivo.The purpose of this Special Issue is to highlight recent achievements in the synthesis and modification of polymers for biomedical applications for final applications in the field of biomedicine.

Technology: general issues --- Biotechnology --- biocomposite --- chitosan --- chlorhexidine --- coating --- hernia --- mesh infection --- nanoparticles --- PLGA --- polypropylene --- rifampicin --- 3D-bioprinting --- static mixer --- reactive hydrogel --- hyaluronic acid --- modified chitosan --- curcumin --- microwave --- interpenetrated polymer network --- semi-IPN --- methacrylated hyaluronic acid --- glycerylphytate --- mesenchymal stem cell --- bioadhesion --- biomaterials --- biomedical application --- healthcare system management --- innovation --- polymer based bioadhesive --- polymers --- magnetite nanoparticles --- Tween 80 --- synthesis --- nanotoxicology --- genotoxicity --- hemotoxicity --- soy protein --- film --- semiconductor --- biomaterial --- additive manufacturing --- sterilization --- medical devices --- bioabsorbable --- polymer --- biopolymer --- hydrogel --- microparticles --- dye release --- drug delivery system --- dual-responsiveness --- dendritic polyglycerol sulfates --- biofabrication --- microfluidics --- electrospinning --- 3D printing --- electrospraying --- natural polymers --- cell encapsulation --- polymeric prodrug --- dual-sensitive --- combination chemotherapy --- drug conjugation --- dextran --- hydrogels --- carboxymethyl cellulose --- succinoglycan --- metal coordination --- drug delivery --- swelling properties --- extracellular matrix --- external stimuli --- tissue maturation --- gelatin --- sodium carboxymethyl cellulose --- scaffold --- A549 cells --- freeze drying --- silicone rubber --- biomechanical --- hyper-elastic --- constitutive model --- FEA --- pH-sensitive hydrogel --- poly(acrylic acid) --- quartz crystal microbalance (QCM) --- ellipsometric measurement --- antibacterial activity --- Ganoderma lucidum --- polysaccharides --- cisplatin --- synergistic effect --- anti-lung cancer --- nanocellulose fiber --- low methoxyl pectin --- sodium alginate --- clindamycin --- pancreatic cancer --- gemcitabine --- controlled release --- non-woven sheet --- chemotherapy --- antitumor efficacy --- poly(L-lactic acid) --- antimicrobials agents --- amphiphilic block copolymer --- quaternized polymer --- hemolysis --- micelle --- black phosphorus --- polyetheretherketone --- lubrication properties --- antibacterial properties --- sensorineural hearing loss --- cochlear implants --- self-bending electrode arrays --- silicone rubber–hydrogel composites --- actuators --- swelling behavior --- curvature --- biocompatibility --- nanofibrous dura mater --- antifibrosis --- neuroprotection --- tetramethylpyrazine --- biocomposite --- chitosan --- chlorhexidine --- coating --- hernia --- mesh infection --- nanoparticles --- PLGA --- polypropylene --- rifampicin --- 3D-bioprinting --- static mixer --- reactive hydrogel --- hyaluronic acid --- modified chitosan --- curcumin --- microwave --- interpenetrated polymer network --- semi-IPN --- methacrylated hyaluronic acid --- glycerylphytate --- mesenchymal stem cell --- bioadhesion --- biomaterials --- biomedical application --- healthcare system management --- innovation --- polymer based bioadhesive --- polymers --- magnetite nanoparticles --- Tween 80 --- synthesis --- nanotoxicology --- genotoxicity --- hemotoxicity --- soy protein --- film --- semiconductor --- biomaterial --- additive manufacturing --- sterilization --- medical devices --- bioabsorbable --- polymer --- biopolymer --- hydrogel --- microparticles --- dye release --- drug delivery system --- dual-responsiveness --- dendritic polyglycerol sulfates --- biofabrication --- microfluidics --- electrospinning --- 3D printing --- electrospraying --- natural polymers --- cell encapsulation --- polymeric prodrug --- dual-sensitive --- combination chemotherapy --- drug conjugation --- dextran --- hydrogels --- carboxymethyl cellulose --- succinoglycan --- metal coordination --- drug delivery --- swelling properties --- extracellular matrix --- external stimuli --- tissue maturation --- gelatin --- sodium carboxymethyl cellulose --- scaffold --- A549 cells --- freeze drying --- silicone rubber --- biomechanical --- hyper-elastic --- constitutive model --- FEA --- pH-sensitive hydrogel --- poly(acrylic acid) --- quartz crystal microbalance (QCM) --- ellipsometric measurement --- antibacterial activity --- Ganoderma lucidum --- polysaccharides --- cisplatin --- synergistic effect --- anti-lung cancer --- nanocellulose fiber --- low methoxyl pectin --- sodium alginate --- clindamycin --- pancreatic cancer --- gemcitabine --- controlled release --- non-woven sheet --- chemotherapy --- antitumor efficacy --- poly(L-lactic acid) --- antimicrobials agents --- amphiphilic block copolymer --- quaternized polymer --- hemolysis --- micelle --- black phosphorus --- polyetheretherketone --- lubrication properties --- antibacterial properties --- sensorineural hearing loss --- cochlear implants --- self-bending electrode arrays --- silicone rubber–hydrogel composites --- actuators --- swelling behavior --- curvature --- biocompatibility --- nanofibrous dura mater --- antifibrosis --- neuroprotection --- tetramethylpyrazine

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Polymers are the largest and most versatile class of biomaterials, being extensively applied for therapeutic applications. From natural to synthetic polymers, the possibilities to design and modify their physical-chemical properties make these systems of great interest in a wide range of biomedical applications as diverse as drug delivery systems, organ-on-a-chip, diagnostics, tissue engineering, and so on.In recent years, advances in the synthesis and modification of polymers and characterization techniques have allowed the design of novel biomaterials as well as the study of their biological behavior in vitro and in vivo.The purpose of this Special Issue is to highlight recent achievements in the synthesis and modification of polymers for biomedical applications for final applications in the field of biomedicine.

biocomposite --- chitosan --- chlorhexidine --- coating --- hernia --- mesh infection --- nanoparticles --- PLGA --- polypropylene --- rifampicin --- 3D-bioprinting --- static mixer --- reactive hydrogel --- hyaluronic acid --- modified chitosan --- curcumin --- microwave --- interpenetrated polymer network --- semi-IPN --- methacrylated hyaluronic acid --- glycerylphytate --- mesenchymal stem cell --- bioadhesion --- biomaterials --- biomedical application --- healthcare system management --- innovation --- polymer based bioadhesive --- polymers --- magnetite nanoparticles --- Tween 80 --- synthesis --- nanotoxicology --- genotoxicity --- hemotoxicity --- soy protein --- film --- semiconductor --- biomaterial --- additive manufacturing --- sterilization --- medical devices --- bioabsorbable --- polymer --- biopolymer --- hydrogel --- microparticles --- dye release --- drug delivery system --- dual-responsiveness --- dendritic polyglycerol sulfates --- biofabrication --- microfluidics --- electrospinning --- 3D printing --- electrospraying --- natural polymers --- cell encapsulation --- polymeric prodrug --- dual-sensitive --- combination chemotherapy --- drug conjugation --- dextran --- hydrogels --- carboxymethyl cellulose --- succinoglycan --- metal coordination --- drug delivery --- swelling properties --- extracellular matrix --- external stimuli --- tissue maturation --- gelatin --- sodium carboxymethyl cellulose --- scaffold --- A549 cells --- freeze drying --- silicone rubber --- biomechanical --- hyper-elastic --- constitutive model --- FEA --- pH-sensitive hydrogel --- poly(acrylic acid) --- quartz crystal microbalance (QCM) --- ellipsometric measurement --- antibacterial activity --- Ganoderma lucidum --- polysaccharides --- cisplatin --- synergistic effect --- anti-lung cancer --- nanocellulose fiber --- low methoxyl pectin --- sodium alginate --- clindamycin --- pancreatic cancer --- gemcitabine --- controlled release --- non-woven sheet --- chemotherapy --- antitumor efficacy --- poly(L-lactic acid) --- antimicrobials agents --- amphiphilic block copolymer --- quaternized polymer --- hemolysis --- micelle --- black phosphorus --- polyetheretherketone --- lubrication properties --- antibacterial properties --- sensorineural hearing loss --- cochlear implants --- self-bending electrode arrays --- silicone rubber–hydrogel composites --- actuators --- swelling behavior --- curvature --- biocompatibility --- nanofibrous dura mater --- antifibrosis --- neuroprotection --- tetramethylpyrazine