Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Recently, the development of polymeric materials for biomedical applications has advanced significantly. Polymeric materials are favored in the development of therapeutic devices, including temporary implants and three-dimensional scaffolds for tissue engineering and in vitro disease modelling.Further advancements have also occurred in the utilization of polymeric materials for pharmacological applications, such as delivery vehicles for drug release.We would like to invite you to contribute to this Special Issue. Research topics of interest include, but are not limited to, recent advances related to 3D cell culture, biomaterials, tissue engineering, disease modelling, hydrogel, organoids, drug discovery, bioimaging, cardio-renal, metabolic disease, and stem cell biology.

Medicine --- Pharmaceutical industries --- hydrogels --- crosslinking --- degradable --- gamma (γ)-irradiation --- sterilization --- sterility assurance --- antibacterial ability --- jojoba --- Simmondsia --- chemistry --- liquid wax --- biology --- toxicity --- pharmaceutical/industrial uses --- articular cartilage --- mechanical properties --- tribological properties --- antibacterial --- pathogens --- infectious diseases --- silver nanoparticles --- wound care --- wound dressings --- polymers --- gelatin --- nanofibers --- sponges --- Ag/RGO nanocomposites --- green preparation --- anticancer performance --- potential mechanism --- oxidative stress --- hydrogel --- poloxamer 407 polymer --- poloxamer 407 gel --- transungual drug delivery --- onychomycosis --- ungual penetration enhancer --- Terbinafine --- diafiltration --- SAXS --- aromatic interactions --- poly(sodium 4-styrenesulfonate) --- chlorpheniramine --- polyelectrolyte --- aggregation --- coaxial electrospinning --- extracellular matrix --- myelination --- oligodendrocyte --- water-soluble materials --- orthokeratology lens --- protein deposition --- optical characteristics --- rubbing --- chitosan --- kenaf --- nanocrystalline cellulose --- platelet lysate --- wound healing --- carbohydrate polymers blends --- functional food --- antioxidant activity --- co-microencapsulation --- spray drying --- bacteria viability (Bacillus clausii) --- probiotics --- itraconazole --- self-emulsifying nanovesicles --- transungual --- anti-fungal --- hydrogels --- crosslinking --- degradable --- gamma (γ)-irradiation --- sterilization --- sterility assurance --- antibacterial ability --- jojoba --- Simmondsia --- chemistry --- liquid wax --- biology --- toxicity --- pharmaceutical/industrial uses --- articular cartilage --- mechanical properties --- tribological properties --- antibacterial --- pathogens --- infectious diseases --- silver nanoparticles --- wound care --- wound dressings --- polymers --- gelatin --- nanofibers --- sponges --- Ag/RGO nanocomposites --- green preparation --- anticancer performance --- potential mechanism --- oxidative stress --- hydrogel --- poloxamer 407 polymer --- poloxamer 407 gel --- transungual drug delivery --- onychomycosis --- ungual penetration enhancer --- Terbinafine --- diafiltration --- SAXS --- aromatic interactions --- poly(sodium 4-styrenesulfonate) --- chlorpheniramine --- polyelectrolyte --- aggregation --- coaxial electrospinning --- extracellular matrix --- myelination --- oligodendrocyte --- water-soluble materials --- orthokeratology lens --- protein deposition --- optical characteristics --- rubbing --- chitosan --- kenaf --- nanocrystalline cellulose --- platelet lysate --- wound healing --- carbohydrate polymers blends --- functional food --- antioxidant activity --- co-microencapsulation --- spray drying --- bacteria viability (Bacillus clausii) --- probiotics --- itraconazole --- self-emulsifying nanovesicles --- transungual --- anti-fungal

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Recently, the development of polymeric materials for biomedical applications has advanced significantly. Polymeric materials are favored in the development of therapeutic devices, including temporary implants and three-dimensional scaffolds for tissue engineering and in vitro disease modelling.Further advancements have also occurred in the utilization of polymeric materials for pharmacological applications, such as delivery vehicles for drug release.We would like to invite you to contribute to this Special Issue. Research topics of interest include, but are not limited to, recent advances related to 3D cell culture, biomaterials, tissue engineering, disease modelling, hydrogel, organoids, drug discovery, bioimaging, cardio-renal, metabolic disease, and stem cell biology.

Medicine --- Pharmaceutical industries --- hydrogels --- crosslinking --- degradable --- gamma (γ)-irradiation --- sterilization --- sterility assurance --- antibacterial ability --- jojoba --- Simmondsia --- chemistry --- liquid wax --- biology --- toxicity --- pharmaceutical/industrial uses --- articular cartilage --- mechanical properties --- tribological properties --- antibacterial --- pathogens --- infectious diseases --- silver nanoparticles --- wound care --- wound dressings --- polymers --- gelatin --- nanofibers --- sponges --- Ag/RGO nanocomposites --- green preparation --- anticancer performance --- potential mechanism --- oxidative stress --- hydrogel --- poloxamer 407 polymer --- poloxamer 407 gel --- transungual drug delivery --- onychomycosis --- ungual penetration enhancer --- Terbinafine --- diafiltration --- SAXS --- aromatic interactions --- poly(sodium 4-styrenesulfonate) --- chlorpheniramine --- polyelectrolyte --- aggregation --- coaxial electrospinning --- extracellular matrix --- myelination --- oligodendrocyte --- water-soluble materials --- orthokeratology lens --- protein deposition --- optical characteristics --- rubbing --- chitosan --- kenaf --- nanocrystalline cellulose --- platelet lysate --- wound healing --- carbohydrate polymers blends --- functional food --- antioxidant activity --- co-microencapsulation --- spray drying --- bacteria viability (Bacillus clausii) --- probiotics --- itraconazole --- self-emulsifying nanovesicles --- transungual --- anti-fungal

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Adipose tissue is a rich, ubiquitous, and easily accessible source for multipotent mesenchymal stromal/stem cells (MSCs), so-called adipose-derived stromal/stem cells (ASCs). Primary isolated ASCs are a heterogeneous preparation consisting of several subpopulations of stromal/stem and precursor cells. Donor-specific differences in ASC isolations and the lack of culture standardization hinder the comparison of results from different studies. Nevertheless, ASCs are already being used in different in vivo models and clinical trials to investigate their ability to improve tissue and organ regeneration. Many questions concerning their counterparts and biology in situ, their differentiation potential in vitro and in vivo, and the mechanisms of regeneration (paracrine effects, including regeneration-promoting factors and extracellular vesicles, differentiation, and immunomodulation) are not completely understood or remain unanswered. This Special Issue covers research articles investigating various adipose tissues as a source for ASC isolation, specific cultures methods to enhance proliferation or viability, and the differentiation capacity. Furthermore, other studies highlight aspects of various diseases, the immunosuppressive potential of ASCs and their derivates, or the in vivo tracking of transplanted ASCs. This edition is complemented by a review that summarizes the current knowledge of spheroid culture system methods and applications for mesenchymal stem cells.

Medicine --- lipomas --- adipose tissue --- stem cells --- adipogenesis --- osteogenesis --- mesenchymal stem cells --- T-cells --- conditioned medium --- extracellular vesicles --- TLR --- INF-γ --- adipose-derived stromal cells --- equine metabolic syndrome --- metformin --- adipose-derived stem cells --- adipocytes --- differentiation --- collagen I --- adiponectin --- integrins --- discoidin domain-containing receptor --- ageing --- subcutaneous fat --- adipose tissue-derived mesenchymal stromal/stem cells (ASCs) --- cell differentiation --- volatile organic compounds --- metabolic monitoring --- adipose-derived stromal/stem cells --- chondrogenesis --- colony forming unit-fibroblast --- fetal bovine serum --- human platelet lysate --- mesenchymal stem cell --- regenerative medicine --- human adipose-derived stem cells --- stem cell proliferation --- signaling pathway --- adipose-derived mesenchymal stem cells --- migration --- secretion --- primary cilium --- sonic hedgehog signaling --- mesenchymal stromal/stem cells --- perirenal --- fat --- characterization --- stimulation --- lipopolysaccharide --- cytokines --- cytomegalovirus --- angiogenesis --- adipose derived mesenchymal cells --- Histogel --- 3D cell culture --- spheroid culture --- biomaterials --- phenotype --- secretory potential --- ankylosing spondylitis --- systemic lupus erythematosus --- systemic sclerosis --- mesenchymal stromal cells --- breast cancer --- tumor microenvironment --- perineural invasion --- adipose derived stem cells --- valproic acid --- protein interactions --- MAPK pathway --- JAK/STAT pathway --- mesenchymal stromal cell --- tissue of origin --- prolonged culture --- epigenetic memory --- tracking --- bio imaging --- bioluminescence --- qRT-PCR --- Ataxia telangiectasia --- Atm --- lipomas --- adipose tissue --- stem cells --- adipogenesis --- osteogenesis --- mesenchymal stem cells --- T-cells --- conditioned medium --- extracellular vesicles --- TLR --- INF-γ --- adipose-derived stromal cells --- equine metabolic syndrome --- metformin --- adipose-derived stem cells --- adipocytes --- differentiation --- collagen I --- adiponectin --- integrins --- discoidin domain-containing receptor --- ageing --- subcutaneous fat --- adipose tissue-derived mesenchymal stromal/stem cells (ASCs) --- cell differentiation --- volatile organic compounds --- metabolic monitoring --- adipose-derived stromal/stem cells --- chondrogenesis --- colony forming unit-fibroblast --- fetal bovine serum --- human platelet lysate --- mesenchymal stem cell --- regenerative medicine --- human adipose-derived stem cells --- stem cell proliferation --- signaling pathway --- adipose-derived mesenchymal stem cells --- migration --- secretion --- primary cilium --- sonic hedgehog signaling --- mesenchymal stromal/stem cells --- perirenal --- fat --- characterization --- stimulation --- lipopolysaccharide --- cytokines --- cytomegalovirus --- angiogenesis --- adipose derived mesenchymal cells --- Histogel --- 3D cell culture --- spheroid culture --- biomaterials --- phenotype --- secretory potential --- ankylosing spondylitis --- systemic lupus erythematosus --- systemic sclerosis --- mesenchymal stromal cells --- breast cancer --- tumor microenvironment --- perineural invasion --- adipose derived stem cells --- valproic acid --- protein interactions --- MAPK pathway --- JAK/STAT pathway --- mesenchymal stromal cell --- tissue of origin --- prolonged culture --- epigenetic memory --- tracking --- bio imaging --- bioluminescence --- qRT-PCR --- Ataxia telangiectasia --- Atm

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Adipose tissue is a rich, ubiquitous, and easily accessible source for multipotent mesenchymal stromal/stem cells (MSCs), so-called adipose-derived stromal/stem cells (ASCs). Primary isolated ASCs are a heterogeneous preparation consisting of several subpopulations of stromal/stem and precursor cells. Donor-specific differences in ASC isolations and the lack of culture standardization hinder the comparison of results from different studies. Nevertheless, ASCs are already being used in different in vivo models and clinical trials to investigate their ability to improve tissue and organ regeneration. Many questions concerning their counterparts and biology in situ, their differentiation potential in vitro and in vivo, and the mechanisms of regeneration (paracrine effects, including regeneration-promoting factors and extracellular vesicles, differentiation, and immunomodulation) are not completely understood or remain unanswered. This Special Issue covers research articles investigating various adipose tissues as a source for ASC isolation, specific cultures methods to enhance proliferation or viability, and the differentiation capacity. Furthermore, other studies highlight aspects of various diseases, the immunosuppressive potential of ASCs and their derivates, or the in vivo tracking of transplanted ASCs. This edition is complemented by a review that summarizes the current knowledge of spheroid culture system methods and applications for mesenchymal stem cells.

lipomas --- adipose tissue --- stem cells --- adipogenesis --- osteogenesis --- mesenchymal stem cells --- T-cells --- conditioned medium --- extracellular vesicles --- TLR --- INF-γ --- adipose-derived stromal cells --- equine metabolic syndrome --- metformin --- adipose-derived stem cells --- adipocytes --- differentiation --- collagen I --- adiponectin --- integrins --- discoidin domain-containing receptor --- ageing --- subcutaneous fat --- adipose tissue-derived mesenchymal stromal/stem cells (ASCs) --- cell differentiation --- volatile organic compounds --- metabolic monitoring --- adipose-derived stromal/stem cells --- chondrogenesis --- colony forming unit-fibroblast --- fetal bovine serum --- human platelet lysate --- mesenchymal stem cell --- regenerative medicine --- human adipose-derived stem cells --- stem cell proliferation --- signaling pathway --- adipose-derived mesenchymal stem cells --- migration --- secretion --- primary cilium --- sonic hedgehog signaling --- mesenchymal stromal/stem cells --- perirenal --- fat --- characterization --- stimulation --- lipopolysaccharide --- cytokines --- cytomegalovirus --- angiogenesis --- adipose derived mesenchymal cells --- Histogel --- 3D cell culture --- spheroid culture --- biomaterials --- phenotype --- secretory potential --- ankylosing spondylitis --- systemic lupus erythematosus --- systemic sclerosis --- mesenchymal stromal cells --- breast cancer --- tumor microenvironment --- perineural invasion --- adipose derived stem cells --- valproic acid --- protein interactions --- MAPK pathway --- JAK/STAT pathway --- mesenchymal stromal cell --- tissue of origin --- prolonged culture --- epigenetic memory --- tracking --- bio imaging --- bioluminescence --- qRT-PCR --- Ataxia telangiectasia --- Atm --- n/a