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Phenytoin

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Adverse drug reactions are one of the major constraints when using drugs. These adverse reactions can impact healthcare systems as strongly as many prevalent diseases. Identifying DNA variants associated with adverse drug reactions can help personalize medicine and sustain healthcare systems. This book delves into new advances in pharmacogenetics of cardiovascular, cancer, and nervous system drugs. It may be useful for clinicians and patients to understand the basics of pharmacogenetics.

5-fluorouracil --- capecitabine --- fluoropyrimidine --- thymidylate synthase --- thymidylate synthase enhancer region --- upstream stimulatory factor 1 --- adverse drug reactions --- pharmacogenomics --- epistasis --- random forest --- statin --- cardiovascular disease --- colorectal cancer --- personalised medicine --- toxicity --- (es)citalopram --- drug-gene-interaction --- drug-drug-interaction --- drug-drug-gene-interaction --- the PharmLines initiative --- antipsychotic agents --- pharmacogenetics --- cytochrome P-450 enzyme system --- psychotic disorders --- precision medicine --- direct oral anticoagulants --- clinical implementation --- atorvastatin --- SLCO1B1 --- HLA --- cutaneous adverse drug reaction --- SCAR --- genetic polymorphism --- antiepileptics --- CYP450 enzymes --- platelet reactivity --- single-nucleotide variants --- acute coronary syndrome --- clopidogrel --- genotype --- allele --- polymorphism --- HLA B --- CYP2C9*3 --- cutaneous adverse drug reactions (CADRs) --- anti-epileptic drugs (AEDS) --- phenytoin (PHT) --- genetic risk factors --- South India --- India --- cardiology --- adverse events --- guidelines --- n/a

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This work covers all aspects related to the obtainment, production, design, and processing of biopolymers obtained from natural resources. Moreover, it studies characteristics related to the improvement of their performance to increase their potential application at an industrial level, in line with the concept of a global circular economy. Thus, this work firstly classifies biopolymers obtained from natural resources (e.g., biobased building blocks and biopolymers extracted directly from plants and biomass), and then summarizes several cutting-edge research works focused on enhancing the performance of biopolymers from natural resources to extend their application in the industrial sector, and contribute to the transition to more sustainable plastics.

Technology: general issues --- History of engineering & technology --- PHBH --- almond shell flour --- mechanical properties --- thermal characterization --- WPCs --- bacterial polyesters --- poly(3-hydroxybutyrate-co-3hydroxyhexanoate)—PHBH --- poly(ε-caprolactone)—PCL --- binary blends --- improved toughness --- mechanical and thermal characterization --- Cucumis metuliferus --- extraction --- antioxidant activity --- coating --- cellulose acetate --- LDPE --- bilayer packaging --- active packaging --- poly(lactic acid) --- mechanical recycling --- yerba mate --- bionanocomposites --- polysulfide-derived polymers --- cottonseed oil --- fatty acid of cottonseed oil --- sodium soap of cottonseed oil --- PLA --- nanocomposites --- functional properties --- thymol --- migration --- films --- cutin --- cuticles --- bioplastics --- biopolymers --- solanum: CPMAS 13C NMR --- softgels --- mucilage --- in vitro digestion --- bioaccessibility --- bran content --- plasticized wheat flour --- citric acid --- biobased blends --- biopolymer --- carboxymethyl cellulose --- solid polymer electrolyte --- ionic transport --- chitosan --- potato starch --- microwave --- foam --- orthogonal experiments --- empty fruit bunch --- regenerated cellulose --- ionic liquid --- methyl methacrylate --- 3D printing --- syringe extrusion 3D printing --- hydroxypropyl methylcellulose --- orodispersible film --- phenytoin --- PA610 --- halloysite nanotubes (HNTs) --- flame retardant --- cone calorimeter --- agricultural waste --- asparagus --- CMC --- degree of substitution --- DS --- cellulose extraction --- thermoplastic starch --- dolomite --- biocomposite --- sonication --- bacterial cellulose --- nata de coco --- sodium hydroxide --- lignin --- nanoparticles --- biorefinery --- organosolv pretreatment --- polyelectrolyte multi-layers --- sodium alginate --- k-carrageenan --- cellulosic nonwoven textile --- surface functionalization --- characterization --- bio-sorption --- isotherms --- natural fibers --- soy protein --- chitin --- coir --- comfort --- functional textiles --- Circular Bioeconomy --- carbonation reaction --- selectivity optimization --- carbonated epoxidized linseed oil --- non-isocyanate polyurethane --- argan shell particles --- wood plastic composite --- polyethylene --- compatibilization --- air permeability --- fungal fibers --- hemp fibers --- microstructure --- mycocel --- softwood fibers --- virus membrane filtration --- allotropic transition --- choline chloride --- plasticizer --- starch dissolution --- n/a --- poly(3-hydroxybutyrate-co-3hydroxyhexanoate)-PHBH --- poly(ε-caprolactone)-PCL

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• Reference Manager
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This work covers all aspects related to the obtainment, production, design, and processing of biopolymers obtained from natural resources. Moreover, it studies characteristics related to the improvement of their performance to increase their potential application at an industrial level, in line with the concept of a global circular economy. Thus, this work firstly classifies biopolymers obtained from natural resources (e.g., biobased building blocks and biopolymers extracted directly from plants and biomass), and then summarizes several cutting-edge research works focused on enhancing the performance of biopolymers from natural resources to extend their application in the industrial sector, and contribute to the transition to more sustainable plastics.

Technology: general issues --- History of engineering & technology --- PHBH --- almond shell flour --- mechanical properties --- thermal characterization --- WPCs --- bacterial polyesters --- poly(3-hydroxybutyrate-co-3hydroxyhexanoate)-PHBH --- poly(ε-caprolactone)-PCL --- binary blends --- improved toughness --- mechanical and thermal characterization --- Cucumis metuliferus --- extraction --- antioxidant activity --- coating --- cellulose acetate --- LDPE --- bilayer packaging --- active packaging --- poly(lactic acid) --- mechanical recycling --- yerba mate --- bionanocomposites --- polysulfide-derived polymers --- cottonseed oil --- fatty acid of cottonseed oil --- sodium soap of cottonseed oil --- PLA --- nanocomposites --- functional properties --- thymol --- migration --- films --- cutin --- cuticles --- bioplastics --- biopolymers --- solanum: CPMAS 13C NMR --- softgels --- mucilage --- in vitro digestion --- bioaccessibility --- bran content --- plasticized wheat flour --- citric acid --- biobased blends --- biopolymer --- carboxymethyl cellulose --- solid polymer electrolyte --- ionic transport --- chitosan --- potato starch --- microwave --- foam --- orthogonal experiments --- empty fruit bunch --- regenerated cellulose --- ionic liquid --- methyl methacrylate --- 3D printing --- syringe extrusion 3D printing --- hydroxypropyl methylcellulose --- orodispersible film --- phenytoin --- PA610 --- halloysite nanotubes (HNTs) --- flame retardant --- cone calorimeter --- agricultural waste --- asparagus --- CMC --- degree of substitution --- DS --- cellulose extraction --- thermoplastic starch --- dolomite --- biocomposite --- sonication --- bacterial cellulose --- nata de coco --- sodium hydroxide --- lignin --- nanoparticles --- biorefinery --- organosolv pretreatment --- polyelectrolyte multi-layers --- sodium alginate --- k-carrageenan --- cellulosic nonwoven textile --- surface functionalization --- characterization --- bio-sorption --- isotherms --- natural fibers --- soy protein --- chitin --- coir --- comfort --- functional textiles --- Circular Bioeconomy --- carbonation reaction --- selectivity optimization --- carbonated epoxidized linseed oil --- non-isocyanate polyurethane --- argan shell particles --- wood plastic composite --- polyethylene --- compatibilization --- air permeability --- fungal fibers --- hemp fibers --- microstructure --- mycocel --- softwood fibers --- virus membrane filtration --- allotropic transition --- choline chloride --- plasticizer --- starch dissolution --- PHBH --- almond shell flour --- mechanical properties --- thermal characterization --- WPCs --- bacterial polyesters --- poly(3-hydroxybutyrate-co-3hydroxyhexanoate)-PHBH --- poly(ε-caprolactone)-PCL --- binary blends --- improved toughness --- mechanical and thermal characterization --- Cucumis metuliferus --- extraction --- antioxidant activity --- coating --- cellulose acetate --- LDPE --- bilayer packaging --- active packaging --- poly(lactic acid) --- mechanical recycling --- yerba mate --- bionanocomposites --- polysulfide-derived polymers --- cottonseed oil --- fatty acid of cottonseed oil --- sodium soap of cottonseed oil --- PLA --- nanocomposites --- functional properties --- thymol --- migration --- films --- cutin --- cuticles --- bioplastics --- biopolymers --- solanum: CPMAS 13C NMR --- softgels --- mucilage --- in vitro digestion --- bioaccessibility --- bran content --- plasticized wheat flour --- citric acid --- biobased blends --- biopolymer --- carboxymethyl cellulose --- solid polymer electrolyte --- ionic transport --- chitosan --- potato starch --- microwave --- foam --- orthogonal experiments --- empty fruit bunch --- regenerated cellulose --- ionic liquid --- methyl methacrylate --- 3D printing --- syringe extrusion 3D printing --- hydroxypropyl methylcellulose --- orodispersible film --- phenytoin --- PA610 --- halloysite nanotubes (HNTs) --- flame retardant --- cone calorimeter --- agricultural waste --- asparagus --- CMC --- degree of substitution --- DS --- cellulose extraction --- thermoplastic starch --- dolomite --- biocomposite --- sonication --- bacterial cellulose --- nata de coco --- sodium hydroxide --- lignin --- nanoparticles --- biorefinery --- organosolv pretreatment --- polyelectrolyte multi-layers --- sodium alginate --- k-carrageenan --- cellulosic nonwoven textile --- surface functionalization --- characterization --- bio-sorption --- isotherms --- natural fibers --- soy protein --- chitin --- coir --- comfort --- functional textiles --- Circular Bioeconomy --- carbonation reaction --- selectivity optimization --- carbonated epoxidized linseed oil --- non-isocyanate polyurethane --- argan shell particles --- wood plastic composite --- polyethylene --- compatibilization --- air permeability --- fungal fibers --- hemp fibers --- microstructure --- mycocel --- softwood fibers --- virus membrane filtration --- allotropic transition --- choline chloride --- plasticizer --- starch dissolution