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Droplet microfluidics has dramatically developed in the past decade and has been established as a microfluidic technology that can translate into commercial products. Its rapid development and adoption have relied not only on an efficient stabilizing system (oil and surfactant), but also on a library of modules that can manipulate droplets at a high-throughput. Droplet microfluidics is a vibrant field that keeps evolving, with advances that span technology development and applications. Recent examples include innovative methods to generate droplets, to perform single-cell encapsulation, magnetic extraction, or sorting at an even higher throughput. The trend consists of improving parameters such as robustness, throughput, or ease of use. These developments rely on a firm understanding of the physics and chemistry involved in hydrodynamic flow at a small scale. Finally, droplet microfluidics has played a pivotal role in biological applications, such as single-cell genomics or high-throughput microbial screening, and chemical applications. This Special Issue will showcase all aspects of the exciting field of droplet microfluidics, including, but not limited to, technology development, applications, and open-source systems.

Technology: general issues --- FADS --- emulsification --- droplet coalescence --- enzyme engineering --- synthetic biology --- droplet formation --- phase field model --- interfacial tension --- glass capillary microfluidic device --- fluidic mixer --- air bubble --- 3D printing --- microcapsules --- double-emulsion drops --- osmotic pressure --- ultra-thin-shell --- microfluidics --- droplet array --- microvalve --- droplets --- lock-in detection --- real-time calibration --- homogeneous immunoassay --- on-chip mergers --- pneumatic valves --- programmable droplet formation --- dilutions --- Microfluidics --- drug combinations --- screening --- droplet microfluidics --- sorting --- passive sorting --- photo-tag --- FADS --- emulsification --- droplet coalescence --- enzyme engineering --- synthetic biology --- droplet formation --- phase field model --- interfacial tension --- glass capillary microfluidic device --- fluidic mixer --- air bubble --- 3D printing --- microcapsules --- double-emulsion drops --- osmotic pressure --- ultra-thin-shell --- microfluidics --- droplet array --- microvalve --- droplets --- lock-in detection --- real-time calibration --- homogeneous immunoassay --- on-chip mergers --- pneumatic valves --- programmable droplet formation --- dilutions --- Microfluidics --- drug combinations --- screening --- droplet microfluidics --- sorting --- passive sorting --- photo-tag

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• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Droplet microfluidics has dramatically developed in the past decade and has been established as a microfluidic technology that can translate into commercial products. Its rapid development and adoption have relied not only on an efficient stabilizing system (oil and surfactant), but also on a library of modules that can manipulate droplets at a high-throughput. Droplet microfluidics is a vibrant field that keeps evolving, with advances that span technology development and applications. Recent examples include innovative methods to generate droplets, to perform single-cell encapsulation, magnetic extraction, or sorting at an even higher throughput. The trend consists of improving parameters such as robustness, throughput, or ease of use. These developments rely on a firm understanding of the physics and chemistry involved in hydrodynamic flow at a small scale. Finally, droplet microfluidics has played a pivotal role in biological applications, such as single-cell genomics or high-throughput microbial screening, and chemical applications. This Special Issue will showcase all aspects of the exciting field of droplet microfluidics, including, but not limited to, technology development, applications, and open-source systems.

FADS --- emulsification --- droplet coalescence --- enzyme engineering --- synthetic biology --- droplet formation --- phase field model --- interfacial tension --- glass capillary microfluidic device --- fluidic mixer --- air bubble --- 3D printing --- microcapsules --- double-emulsion drops --- osmotic pressure --- ultra-thin-shell --- microfluidics --- droplet array --- microvalve --- droplets --- lock-in detection --- real-time calibration --- homogeneous immunoassay --- on-chip mergers --- pneumatic valves --- programmable droplet formation --- dilutions --- Microfluidics --- drug combinations --- screening --- droplet microfluidics --- sorting --- passive sorting --- photo-tag --- n/a

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This book offers a collection of 17 scientific papers about the computational modeling of fracture. Some of the manuscripts propose new computational methods and/or how to improve existing cutting edge methods for fracture. These contributions can be classified into two categories: 1. Methods which treat the crack as strong discontinuity such as peridynamics, scaled boundary elements or specific versions of the smoothed finite element methods applied to fracture and 2. Continuous approaches to fracture based on, for instance, phase field models or continuum damage mechanics. On the other hand, the book also offers a wide range of applications where state-of-the-art techniques are employed to solve challenging engineering problems such as fractures in rock, glass, concrete. Also, larger systems such as fracture in subway stations due to fire, arch dams, or concrete decks are studied.

Brittle Fracture --- n/a --- microstructure --- fatigue crack growth --- fracture process zone (FPZ) --- crack shape change --- fracture network modeling --- Mohr-Coulomb --- fracture --- SBFEM --- topological insulator --- fatigue --- progressive collapse analysis --- Phase-field model --- loss of key components --- concrete creep --- compressive stress --- rail squats --- cracks --- force transfer --- rolling contact --- damage-plasticity model --- implicit gradient-enhancement --- extended scaled boundary finite element method (X-SBFEM) --- three-parameter model --- LEFM --- overall stability --- EPB shield machine --- metallic glass matrix composite --- phase field --- reinforced concrete core tube --- bulk damage --- ductility --- thermomechanical analysis --- incompatible approximation --- moderate fire --- finite element simulations --- shear failure --- FSDT --- gradient-enhanced model --- prestressing stress --- self-healing --- peridynamics --- damage-healing mechanics --- stress intensity factors --- damage --- dam stress zones --- shear band --- rock fracture --- random fracture --- surface crack --- plate --- steel reinforced concrete frame --- super healing --- brittle material --- geometric phase --- FE analysis --- grouting --- rock --- elastoplastic behavior --- parameters calibration --- screened-Poisson model --- anisotropic --- numerical simulation --- Discontinuous Galerkin --- brittle fracture --- XFEM/GFEM --- topological photonic crystal --- photonic orbital angular momentum --- conditioned sandy pebble --- yielding region --- finite element analysis --- fluid–structure interaction --- cracking risk --- Mindlin --- ABAQUS UEL --- particle element model --- HSDT --- cell-based smoothed-finite element method (CS-FEM) --- the Xulong arch dam --- fluid-structure interaction