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Development of new drug molecules is costly and requires longitudinal, wide-ranging studies; therefore, designing advanced pharmaceutical formulations for existing and well-known drugs seems to be an attractive device for the pharmaceutical industry. Properly formulated drug delivery systems can improve pharmacological activity, efficacy and safety of the active substances. Advanced materials applied as pharmaceutical excipients in designing drug delivery systems can help solve problems concerning the required drug release—with the defined dissolution rate and at the determined site. Novel drug carriers enable more effective drug delivery, with improved safety and with fewer side effects. Investigations concerning advanced materials represent a rapidly growing research field in material/polymer science, chemical engineering and pharmaceutical technology. Exploring novel materials or modifying and combining existing ones is now a crucial trend in pharmaceutical technology. Eleven articles included in the the Special Issue “Advanced Materials in Drug Release and Drug Delivery Systems” present the most recent insights into the utilization of different materials with promising potential in drug delivery and into different formulation approaches that can be used in the design of pharmaceutical formulations.

Technology: general issues --- mesoporous silica --- layer-by-layer --- FITC-peptide --- hyaluronic acid --- multilayer film --- host-guest interaction --- total alkaloids from Alstonia scholaris leaves --- mPEG-PLA --- microspheres --- drug release --- biocompatibility --- CO administration --- therapeutic agent --- pharmaceutical drugs --- heme oxygenase --- CO-releasing materials --- CO-releasing molecules --- organometallic complexes --- pharmacokinetic functions --- pathological role --- CO kinetic profile --- cellular targets --- GQDs --- real-time tracking --- optical-magneto nanoparticles --- in vivo --- ethylcellulose --- polymeric material --- cellulose derivative --- pharmaceutical excipient --- hydrogel --- drug delivery --- polymer --- immobilization of drug --- gelatin --- gastro-resistant --- films --- capsules --- structure --- sirolimus --- electrospinning --- polycaprolactone --- 3D matrix --- drug-eluting stents --- spray drying --- microparticles --- rupatadine fumarate --- orodispersible minitablets --- taste masking --- Bicalutamide --- Poloxamer® 407 --- Macrogol 6000 --- supercritical carbon dioxide --- solid dispersions --- dissolution rate --- amorphization --- 3D printing --- fused deposition modeling --- hot-melt extrusion --- solid dosage forms --- itraconazole --- n/a

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Development of new drug molecules is costly and requires longitudinal, wide-ranging studies; therefore, designing advanced pharmaceutical formulations for existing and well-known drugs seems to be an attractive device for the pharmaceutical industry. Properly formulated drug delivery systems can improve pharmacological activity, efficacy and safety of the active substances. Advanced materials applied as pharmaceutical excipients in designing drug delivery systems can help solve problems concerning the required drug release—with the defined dissolution rate and at the determined site. Novel drug carriers enable more effective drug delivery, with improved safety and with fewer side effects. Investigations concerning advanced materials represent a rapidly growing research field in material/polymer science, chemical engineering and pharmaceutical technology. Exploring novel materials or modifying and combining existing ones is now a crucial trend in pharmaceutical technology. Eleven articles included in the the Special Issue “Advanced Materials in Drug Release and Drug Delivery Systems” present the most recent insights into the utilization of different materials with promising potential in drug delivery and into different formulation approaches that can be used in the design of pharmaceutical formulations.

Technology: general issues --- mesoporous silica --- layer-by-layer --- FITC-peptide --- hyaluronic acid --- multilayer film --- host-guest interaction --- total alkaloids from Alstonia scholaris leaves --- mPEG-PLA --- microspheres --- drug release --- biocompatibility --- CO administration --- therapeutic agent --- pharmaceutical drugs --- heme oxygenase --- CO-releasing materials --- CO-releasing molecules --- organometallic complexes --- pharmacokinetic functions --- pathological role --- CO kinetic profile --- cellular targets --- GQDs --- real-time tracking --- optical-magneto nanoparticles --- in vivo --- ethylcellulose --- polymeric material --- cellulose derivative --- pharmaceutical excipient --- hydrogel --- drug delivery --- polymer --- immobilization of drug --- gelatin --- gastro-resistant --- films --- capsules --- structure --- sirolimus --- electrospinning --- polycaprolactone --- 3D matrix --- drug-eluting stents --- spray drying --- microparticles --- rupatadine fumarate --- orodispersible minitablets --- taste masking --- Bicalutamide --- Poloxamer® 407 --- Macrogol 6000 --- supercritical carbon dioxide --- solid dispersions --- dissolution rate --- amorphization --- 3D printing --- fused deposition modeling --- hot-melt extrusion --- solid dosage forms --- itraconazole

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Daniel M. Fox gives an incisive assessment of the critical collaboration between researchers and public officials that has recently emerged to evaluate the effectiveness and comparative effectiveness of health services. Drawing on research as well as his first-hand experience in policymaking, Fox's broad-ranging analysis describes how politics, public finance and management, and advances in research methods made this convergence of science and governance possible. The book then widens into a sweeping history of central issues in research on health services and health governance during the past century. Returning to the past decade, Fox looks closely at how policy informed by research has been made and implemented in public programs that cover pharmaceutical drugs in most American states. This case study illuminates how politics has informed the questions, methods, and reception of research on health services, and also sheds new light on how research has informed politics and public management. Looking toward the future, Fox describes the promise, as well as the fragility, of the convergence of science and governance, making his book essential reading for those struggling to revise health care in the United States over the next several years.

Politics --- History, 21st Century --- History, 20th Century --- Health Services Research --- Health Policy --- Government Programs --- Insurance, Pharmaceutical Services --- National health services --- Pharmaceutical policy --- Medical policy --- Insurance, Pharmaceutic Services --- Insurance, Pharmacy Services --- Pharmaceutic Services Insurance --- Pharmaceutical Services Insurance --- Pharmacy Services Insurance --- Drug Benefit Plans --- Drug Insurance --- Prescription Insurance --- Drug Benefit Plan --- Insurance, Drug --- Insurance, Prescription --- Plan, Drug Benefit --- Plans, Drug Benefit --- Pharmacy Administration --- Government Sponsored Programs --- Government-Sponsored Programs --- Government Program --- Government Sponsored Program --- Government-Sponsored Program --- Program, Government --- Program, Government Sponsored --- Program, Government-Sponsored --- Programs, Government --- Programs, Government Sponsored --- Programs, Government-Sponsored --- National Health Programs --- Healthcare Policy --- National Health Policy --- Health Policies --- Health Policy, National --- Healthcare Policies --- National Health Policies --- Policy, Health --- Policy, Healthcare --- Policy, National Health --- Policy Making --- Action Research --- Health Services Evaluation --- Healthcare Research --- Research, Medical Care --- Health Care Research --- Medical Care Research --- Research, Health Services --- Evaluation, Health Services --- Evaluations, Health Services --- Health Services Evaluations --- Research, Action --- Research, Health Care --- Research, Healthcare --- 20th Cent. History (Medicine) --- 20th Cent. History of Medicine --- 20th Cent. Medicine --- Historical Events, 20th Century --- History of Medicine, 20th Cent. --- History, Twentieth Century --- Medical History, 20th Cent. --- Medicine, 20th Cent. --- 20th Century History --- 20th Cent. Histories (Medicine) --- 20th Century Histories --- Cent. Histories, 20th (Medicine) --- Cent. History, 20th (Medicine) --- Century Histories, 20th --- Century Histories, Twentieth --- Century History, 20th --- Century History, Twentieth --- Histories, 20th Cent. (Medicine) --- Histories, 20th Century --- Histories, Twentieth Century --- History, 20th Cent. (Medicine) --- Twentieth Century Histories --- Twentieth Century History --- 21st Cent. History (Medicine) --- 21st Cent. History of Medicine --- 21st Cent. Medicine --- Historical Events, 21st Century --- History of Medicine, 21st Cent. --- History, Twenty-first Century --- Medical History, 21st Cent. --- Medicine, 21st Cent. --- 21st Century History --- 21st Cent. Histories (Medicine) --- 21st Cent. Medicines --- 21st Century Histories --- Cent. Histories, 21st (Medicine) --- Cent. History, 21st (Medicine) --- Cent. Medicine, 21st --- Cent. Medicines, 21st --- Century Histories, 21st --- Century Histories, Twenty-first --- Century History, 21st --- Century History, Twenty-first --- Histories, 21st Cent. (Medicine) --- Histories, 21st Century --- Histories, Twenty-first Century --- History, 21st Cent. (Medicine) --- History, Twenty first Century --- Medicines, 21st Cent. --- Twenty-first Century Histories --- Twenty-first Century History --- Conservatism --- Decentralization --- Liberalism --- Political Factors --- Voting --- Political Activity --- Activities, Political --- Activity, Political --- Factor, Political --- Factors, Political --- Political Activities --- Political Factor --- Dissent and Disputes --- history --- american health policies. --- case studies. --- civic. --- disease. --- easy to read. --- engaging. --- governance. --- government. --- health care revision. --- health governance. --- health policy. --- health services. --- medicine. --- nonfiction. --- pharmaceutical drugs. --- policy makers. --- policymaking. --- political. --- politics. --- public finance. --- public management. --- public officials. --- public policy. --- public programs. --- research methods. --- research. --- science. --- students and teachers. --- textbooks. --- theoretical. --- united states.