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Molecular docking is a widely used bioinformatics method in biology, medicine, and biochemistry. This method, which can model interactions between different receptors and their various ligands at the molecular level, can represent intermolecular interactions at an unprecedented resolution that may not be achieved by classical experimental approaches. This book describes different aspects of this method that can reveal the intermolecular biochemical and biophysical interactions and the affinities of partner molecules to each other. It is designed for academics, students, and professionals interested in this technique.
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Molecular docking is a widely used bioinformatics method in biology, medicine, and biochemistry. This method, which can model interactions between different receptors and their various ligands at the molecular level, can represent intermolecular interactions at an unprecedented resolution that may not be achieved by classical experimental approaches. This book describes different aspects of this method that can reveal the intermolecular biochemical and biophysical interactions and the affinities of partner molecules to each other. It is designed for academics, students, and professionals interested in this technique.
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From a managerial perspective, the biopharmaceutical industry represents a competitive, fast-changing, intellectually-powered, innovation-driven sector. Many management scholars have studied this discontinuous era to make sense of strategic behavior and the cognition of firms and top managers. A past look at the biopharmaceutical industry provides answers to questions that most managers have. For example, what options do you have and what actions do you take when new firms enter your industry? In the 1970s, new biotechnology firms, funded by venture capitalists, appeared in the pharmaceutical industry with new knowledge. Successful pharmaceutical firms decided to collaborate with the new entrants and forge relationships to develop and create new, biotechnology engineered drugs. Thus, the addition of new biotechnology firms ushered in a new business model based on strategic alliances. Strategic alliances have now become an industrial norm called open innovation. The author looks at the historical path of the biopharmaceutical industry, particularly in the United States. While the pharmaceutical industry’s main contributions to society are substantial, there are pressing challenges the industry must face, such as an increase in infectious disease outbreaks or the global aging population, which require new types of care, additionally, mental health care and prescription painkiller addiction are persistent issues with economic repercussions to both federal and local governments. This book presents a holistic view of the biopharmaceutical industry, putting it in a historical context. It will best serve those who are eager to learn about this dynamic, fast-evolving industry andwho would like to tackle current biopharmaceutical industry issues in the United States and be prepared for future industry challenges.
Pharmaceutical biotechnology industry --- Pharmaceutical biotechnology --- History.
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