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2022 (6)

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Book
Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer
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Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

This book—entitled “Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer”—was edited as a Special Issue of Biomedicines, focusing on basic research such as genomics, epigenomics, and proteomics, as well as clinical research in the field of gynecologic oncology. The number of patients with gynecological cancer has been increasing worldwide due to its high lethality and lack of early detection tools and effective therapeutic interventions. In this regard, basic research on its pathophysiology and novel molecular targeting intervention is required to improve the prognosis of gynecologic cancer. This book contains 13 papers, including 8 original research papers and 5 reviews focusing on the basic research of gynecologic oncology. The reader can learn about state-of-the-art research and obtain extensive knowledge of the current advances in the field of gynecologic oncology. It is my hope that this book contributes towards the progress of gynecologic oncology.

Keywords

Public health & preventive medicine --- nucleus accumbens-associated protein 1 (NAC1) --- BEN (BANP, E5R and NAC1) domain --- sequence-specific DNA-binding protein --- solution NMR structure --- isothermal titration calorimetry (ITC) --- human cytomegalovirus --- ovarian cancer --- cancer progression --- inflammation --- immunosuppression --- endometrial carcinoma --- immune micro-environment --- immune checkpoints inhibitors --- microsatellite instability --- mismatch repair deficiency --- platelet-activating factor acetylhydrolase (PAF-AH --- PLA2G7) --- BRCA1 mutant ovarian cancer --- Wnt signaling --- pGSK3β --- β-catenin --- prognosis --- vulvar melanoma --- vaginal melanoma --- targeted therapy --- gynecological cancer --- melanoma treatment --- gene ontology --- epithelial ovarian cancers --- borderline ovarian tumors --- differentially expressed genes --- aryl hydrocarbon receptor --- epithelial-mesenchymal transition --- integrative analysis --- testin --- p16 protein --- cervical cancer --- cervical neoplasia --- immunohistochemistry --- chimeric antigen receptor --- CD44 --- adoptive immunotherapy --- NK cells --- epithelial ovarian cancer --- DNA damage response --- somatic mutation --- clear cell carcinoma --- endometrioid endometrial cancer --- DNA mismatch repair (MMR) --- MMR deficient (dMMR) --- long-term survival --- exosome --- miRNA --- biomarkers --- liquid biopsy --- interventional radiotherapy --- vaginal-cuff brachytherapy --- HDR brachytherapy --- in vivo dosimetry --- endometrial cancer --- biological planning --- drug repurposing --- non-coding RNAs --- nanocarriers --- anti-angiogenic therapy --- nucleus accumbens-associated protein 1 (NAC1) --- BEN (BANP, E5R and NAC1) domain --- sequence-specific DNA-binding protein --- solution NMR structure --- isothermal titration calorimetry (ITC) --- human cytomegalovirus --- ovarian cancer --- cancer progression --- inflammation --- immunosuppression --- endometrial carcinoma --- immune micro-environment --- immune checkpoints inhibitors --- microsatellite instability --- mismatch repair deficiency --- platelet-activating factor acetylhydrolase (PAF-AH --- PLA2G7) --- BRCA1 mutant ovarian cancer --- Wnt signaling --- pGSK3β --- β-catenin --- prognosis --- vulvar melanoma --- vaginal melanoma --- targeted therapy --- gynecological cancer --- melanoma treatment --- gene ontology --- epithelial ovarian cancers --- borderline ovarian tumors --- differentially expressed genes --- aryl hydrocarbon receptor --- epithelial-mesenchymal transition --- integrative analysis --- testin --- p16 protein --- cervical cancer --- cervical neoplasia --- immunohistochemistry --- chimeric antigen receptor --- CD44 --- adoptive immunotherapy --- NK cells --- epithelial ovarian cancer --- DNA damage response --- somatic mutation --- clear cell carcinoma --- endometrioid endometrial cancer --- DNA mismatch repair (MMR) --- MMR deficient (dMMR) --- long-term survival --- exosome --- miRNA --- biomarkers --- liquid biopsy --- interventional radiotherapy --- vaginal-cuff brachytherapy --- HDR brachytherapy --- in vivo dosimetry --- endometrial cancer --- biological planning --- drug repurposing --- non-coding RNAs --- nanocarriers --- anti-angiogenic therapy


Book
Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer
Author:
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

This book—entitled “Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer”—was edited as a Special Issue of Biomedicines, focusing on basic research such as genomics, epigenomics, and proteomics, as well as clinical research in the field of gynecologic oncology. The number of patients with gynecological cancer has been increasing worldwide due to its high lethality and lack of early detection tools and effective therapeutic interventions. In this regard, basic research on its pathophysiology and novel molecular targeting intervention is required to improve the prognosis of gynecologic cancer. This book contains 13 papers, including 8 original research papers and 5 reviews focusing on the basic research of gynecologic oncology. The reader can learn about state-of-the-art research and obtain extensive knowledge of the current advances in the field of gynecologic oncology. It is my hope that this book contributes towards the progress of gynecologic oncology.

Keywords

Public health & preventive medicine --- nucleus accumbens-associated protein 1 (NAC1) --- BEN (BANP, E5R and NAC1) domain --- sequence-specific DNA-binding protein --- solution NMR structure --- isothermal titration calorimetry (ITC) --- human cytomegalovirus --- ovarian cancer --- cancer progression --- inflammation --- immunosuppression --- endometrial carcinoma --- immune micro-environment --- immune checkpoints inhibitors --- microsatellite instability --- mismatch repair deficiency --- platelet-activating factor acetylhydrolase (PAF-AH --- PLA2G7) --- BRCA1 mutant ovarian cancer --- Wnt signaling --- pGSK3β --- β-catenin --- prognosis --- vulvar melanoma --- vaginal melanoma --- targeted therapy --- gynecological cancer --- melanoma treatment --- gene ontology --- epithelial ovarian cancers --- borderline ovarian tumors --- differentially expressed genes --- aryl hydrocarbon receptor --- epithelial–mesenchymal transition --- integrative analysis --- testin --- p16 protein --- cervical cancer --- cervical neoplasia --- immunohistochemistry --- chimeric antigen receptor --- CD44 --- adoptive immunotherapy --- NK cells --- epithelial ovarian cancer --- DNA damage response --- somatic mutation --- clear cell carcinoma --- endometrioid endometrial cancer --- DNA mismatch repair (MMR) --- MMR deficient (dMMR) --- long-term survival --- exosome --- miRNA --- biomarkers --- liquid biopsy --- interventional radiotherapy --- vaginal-cuff brachytherapy --- HDR brachytherapy --- in vivo dosimetry --- endometrial cancer --- biological planning --- drug repurposing --- non-coding RNAs --- nanocarriers --- anti-angiogenic therapy --- n/a --- epithelial-mesenchymal transition


Book
Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer
Author:
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

This book—entitled “Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer”—was edited as a Special Issue of Biomedicines, focusing on basic research such as genomics, epigenomics, and proteomics, as well as clinical research in the field of gynecologic oncology. The number of patients with gynecological cancer has been increasing worldwide due to its high lethality and lack of early detection tools and effective therapeutic interventions. In this regard, basic research on its pathophysiology and novel molecular targeting intervention is required to improve the prognosis of gynecologic cancer. This book contains 13 papers, including 8 original research papers and 5 reviews focusing on the basic research of gynecologic oncology. The reader can learn about state-of-the-art research and obtain extensive knowledge of the current advances in the field of gynecologic oncology. It is my hope that this book contributes towards the progress of gynecologic oncology.

Keywords

nucleus accumbens-associated protein 1 (NAC1) --- BEN (BANP, E5R and NAC1) domain --- sequence-specific DNA-binding protein --- solution NMR structure --- isothermal titration calorimetry (ITC) --- human cytomegalovirus --- ovarian cancer --- cancer progression --- inflammation --- immunosuppression --- endometrial carcinoma --- immune micro-environment --- immune checkpoints inhibitors --- microsatellite instability --- mismatch repair deficiency --- platelet-activating factor acetylhydrolase (PAF-AH --- PLA2G7) --- BRCA1 mutant ovarian cancer --- Wnt signaling --- pGSK3β --- β-catenin --- prognosis --- vulvar melanoma --- vaginal melanoma --- targeted therapy --- gynecological cancer --- melanoma treatment --- gene ontology --- epithelial ovarian cancers --- borderline ovarian tumors --- differentially expressed genes --- aryl hydrocarbon receptor --- epithelial–mesenchymal transition --- integrative analysis --- testin --- p16 protein --- cervical cancer --- cervical neoplasia --- immunohistochemistry --- chimeric antigen receptor --- CD44 --- adoptive immunotherapy --- NK cells --- epithelial ovarian cancer --- DNA damage response --- somatic mutation --- clear cell carcinoma --- endometrioid endometrial cancer --- DNA mismatch repair (MMR) --- MMR deficient (dMMR) --- long-term survival --- exosome --- miRNA --- biomarkers --- liquid biopsy --- interventional radiotherapy --- vaginal-cuff brachytherapy --- HDR brachytherapy --- in vivo dosimetry --- endometrial cancer --- biological planning --- drug repurposing --- non-coding RNAs --- nanocarriers --- anti-angiogenic therapy --- n/a --- epithelial-mesenchymal transition


Book
Community and Family-Focused Public Health and Sustainable Development
Authors: --- --- ---
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

The book “Community and Family-Focused Public Health and Sustainable Development” was originally published in the renowned International Journal of Environmental Research and Public Health. This Special Issue encompassed novel aspects of applications that are connected with sustainability issues in community and family-focused public health studies. Contributions have a significant impact on solving public health problems at the family and community levels. The Special Issue originally published scientific papers, including review articles, that fell under this Special Issue’s remit and that were relevant to audiences worldwide. Currently, the term “family health” is most commonly to describe mother and child health and reproductive health. It is rare for family health to include the family as an important context for health development and that includes all family members and the family’s social environment. Authors of scientific research covering issues related to the impact of the family and the environment in which the family lives and functions on its members’ health in the present and in the future were encouraged to contribute their work. In addition, we were especially interested in scientific reports on social, economic, and health inequalities in the context of achieving the sustainable development goals.

Keywords

Public health & preventive medicine --- family --- living with children --- parenthood --- mother --- father --- self-rated health --- health behavior --- mental health --- Germany --- gut microbiome --- antimicrobial activity --- pathogen overgrowth --- smoking --- tobacco smoke --- exposure to tobacco smoke --- ETS --- anti-tobacco law --- hospitality venues --- quality of life --- the elderly --- seniors --- health --- cardiovascular diseases --- physical and psychological well-being --- health behaviors --- pregnancy --- rural area --- urban area --- CHEK2 --- MEN --- Cushing syndrome --- hypertension --- multiple endocrine glands tumors --- cervix uteri --- epidemiology --- screening --- mortality --- time trends --- east-central Europe --- depression --- bone markers --- osteocalcin --- β-CTX --- vitamin D --- metabolomics --- metabolites --- amino acids --- biomarkers --- asthma --- diagnosis --- children --- community health services --- postmodern education theories --- factor analysis --- genetic testing --- umbilical cord blood banking --- women health --- air pollution --- PM2.5 --- pregnancy outcomes --- sustainable development --- spatio-temporal data --- NUTS-1 --- kernel discriminant coordinates method --- super macroregions --- proteomics --- mass spectrometry --- MALDI-MSI --- tissue imaging --- ovarian tumors --- gestational diabetes mellitus --- diabetes --- obesity --- cesarean section --- health policy --- health inequalities --- healthcare access --- spatial distribution of the health situation --- cluster analysis --- functional discriminant coordinates --- multivariate functional coefficient of variation --- adenomyosis --- infertility --- GnRH --- in vitro fertilisation --- type 1 diabetes --- proteomic profile --- C4 complement --- PURE study --- noncommunicable diseases --- urban --- rural --- FRAP --- TBARS --- anaerobic threshold --- peakVO2 --- lifestyle --- training --- exercises --- intergenerational relations --- academic youth --- standardized questionnaire WHOQOL-BREF --- alcohol --- cohort study --- PURE --- pro-health behaviours --- anti-health behaviour --- prevention --- patient --- 50+ population --- chronic diseases --- special motor fitness --- speed --- flexibility --- endurance --- physical activity --- health training --- women --- WHOQOL-BREF questionnaire --- Bangladesh --- gender violence --- multidimensional poverty --- poverty reduction --- women’s empowerment --- color vision --- anomaloscope --- Moreland --- Rayleigh --- Hashimoto’s disease --- oxidative stress --- zinc --- copper --- child health --- child nutrition --- dairy --- food security --- food systems --- nutrition --- sustainability --- sustainable food systems --- working population --- Poland --- Ukraine --- spinal cord injury --- hematological parameters --- peak oxygen uptake --- sleep duration --- bedtime --- access to health care --- health care services --- hospital emergency departments --- spatial analysis --- public health management --- testosterone --- cortisol --- creatinine --- overtraining --- family --- living with children --- parenthood --- mother --- father --- self-rated health --- health behavior --- mental health --- Germany --- gut microbiome --- antimicrobial activity --- pathogen overgrowth --- smoking --- tobacco smoke --- exposure to tobacco smoke --- ETS --- anti-tobacco law --- hospitality venues --- quality of life --- the elderly --- seniors --- health --- cardiovascular diseases --- physical and psychological well-being --- health behaviors --- pregnancy --- rural area --- urban area --- CHEK2 --- MEN --- Cushing syndrome --- hypertension --- multiple endocrine glands tumors --- cervix uteri --- epidemiology --- screening --- mortality --- time trends --- east-central Europe --- depression --- bone markers --- osteocalcin --- β-CTX --- vitamin D --- metabolomics --- metabolites --- amino acids --- biomarkers --- asthma --- diagnosis --- children --- community health services --- postmodern education theories --- factor analysis --- genetic testing --- umbilical cord blood banking --- women health --- air pollution --- PM2.5 --- pregnancy outcomes --- sustainable development --- spatio-temporal data --- NUTS-1 --- kernel discriminant coordinates method --- super macroregions --- proteomics --- mass spectrometry --- MALDI-MSI --- tissue imaging --- ovarian tumors --- gestational diabetes mellitus --- diabetes --- obesity --- cesarean section --- health policy --- health inequalities --- healthcare access --- spatial distribution of the health situation --- cluster analysis --- functional discriminant coordinates --- multivariate functional coefficient of variation --- adenomyosis --- infertility --- GnRH --- in vitro fertilisation --- type 1 diabetes --- proteomic profile --- C4 complement --- PURE study --- noncommunicable diseases --- urban --- rural --- FRAP --- TBARS --- anaerobic threshold --- peakVO2 --- lifestyle --- training --- exercises --- intergenerational relations --- academic youth --- standardized questionnaire WHOQOL-BREF --- alcohol --- cohort study --- PURE --- pro-health behaviours --- anti-health behaviour --- prevention --- patient --- 50+ population --- chronic diseases --- special motor fitness --- speed --- flexibility --- endurance --- physical activity --- health training --- women --- WHOQOL-BREF questionnaire --- Bangladesh --- gender violence --- multidimensional poverty --- poverty reduction --- women’s empowerment --- color vision --- anomaloscope --- Moreland --- Rayleigh --- Hashimoto’s disease --- oxidative stress --- zinc --- copper --- child health --- child nutrition --- dairy --- food security --- food systems --- nutrition --- sustainability --- sustainable food systems --- working population --- Poland --- Ukraine --- spinal cord injury --- hematological parameters --- peak oxygen uptake --- sleep duration --- bedtime --- access to health care --- health care services --- hospital emergency departments --- spatial analysis --- public health management --- testosterone --- cortisol --- creatinine --- overtraining


Book
Community and Family-Focused Public Health and Sustainable Development
Authors: --- --- ---
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

The book “Community and Family-Focused Public Health and Sustainable Development” was originally published in the renowned International Journal of Environmental Research and Public Health. This Special Issue encompassed novel aspects of applications that are connected with sustainability issues in community and family-focused public health studies. Contributions have a significant impact on solving public health problems at the family and community levels. The Special Issue originally published scientific papers, including review articles, that fell under this Special Issue’s remit and that were relevant to audiences worldwide. Currently, the term “family health” is most commonly to describe mother and child health and reproductive health. It is rare for family health to include the family as an important context for health development and that includes all family members and the family’s social environment. Authors of scientific research covering issues related to the impact of the family and the environment in which the family lives and functions on its members’ health in the present and in the future were encouraged to contribute their work. In addition, we were especially interested in scientific reports on social, economic, and health inequalities in the context of achieving the sustainable development goals.

Keywords

Public health & preventive medicine --- family --- living with children --- parenthood --- mother --- father --- self-rated health --- health behavior --- mental health --- Germany --- gut microbiome --- antimicrobial activity --- pathogen overgrowth --- smoking --- tobacco smoke --- exposure to tobacco smoke --- ETS --- anti-tobacco law --- hospitality venues --- quality of life --- the elderly --- seniors --- health --- cardiovascular diseases --- physical and psychological well-being --- health behaviors --- pregnancy --- rural area --- urban area --- CHEK2 --- MEN --- Cushing syndrome --- hypertension --- multiple endocrine glands tumors --- cervix uteri --- epidemiology --- screening --- mortality --- time trends --- east-central Europe --- depression --- bone markers --- osteocalcin --- β-CTX --- vitamin D --- metabolomics --- metabolites --- amino acids --- biomarkers --- asthma --- diagnosis --- children --- community health services --- postmodern education theories --- factor analysis --- genetic testing --- umbilical cord blood banking --- women health --- air pollution --- PM2.5 --- pregnancy outcomes --- sustainable development --- spatio-temporal data --- NUTS-1 --- kernel discriminant coordinates method --- super macroregions --- proteomics --- mass spectrometry --- MALDI-MSI --- tissue imaging --- ovarian tumors --- gestational diabetes mellitus --- diabetes --- obesity --- cesarean section --- health policy --- health inequalities --- healthcare access --- spatial distribution of the health situation --- cluster analysis --- functional discriminant coordinates --- multivariate functional coefficient of variation --- adenomyosis --- infertility --- GnRH --- in vitro fertilisation --- type 1 diabetes --- proteomic profile --- C4 complement --- PURE study --- noncommunicable diseases --- urban --- rural --- FRAP --- TBARS --- anaerobic threshold --- peakVO2 --- lifestyle --- training --- exercises --- intergenerational relations --- academic youth --- standardized questionnaire WHOQOL-BREF --- alcohol --- cohort study --- PURE --- pro-health behaviours --- anti-health behaviour --- prevention --- patient --- 50+ population --- chronic diseases --- special motor fitness --- speed --- flexibility --- endurance --- physical activity --- health training --- women --- WHOQOL-BREF questionnaire --- Bangladesh --- gender violence --- multidimensional poverty --- poverty reduction --- women’s empowerment --- color vision --- anomaloscope --- Moreland --- Rayleigh --- Hashimoto’s disease --- oxidative stress --- zinc --- copper --- child health --- child nutrition --- dairy --- food security --- food systems --- nutrition --- sustainability --- sustainable food systems --- working population --- Poland --- Ukraine --- spinal cord injury --- hematological parameters --- peak oxygen uptake --- sleep duration --- bedtime --- access to health care --- health care services --- hospital emergency departments --- spatial analysis --- public health management --- testosterone --- cortisol --- creatinine --- overtraining


Book
Community and Family-Focused Public Health and Sustainable Development
Authors: --- --- ---
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

The book “Community and Family-Focused Public Health and Sustainable Development” was originally published in the renowned International Journal of Environmental Research and Public Health. This Special Issue encompassed novel aspects of applications that are connected with sustainability issues in community and family-focused public health studies. Contributions have a significant impact on solving public health problems at the family and community levels. The Special Issue originally published scientific papers, including review articles, that fell under this Special Issue’s remit and that were relevant to audiences worldwide. Currently, the term “family health” is most commonly to describe mother and child health and reproductive health. It is rare for family health to include the family as an important context for health development and that includes all family members and the family’s social environment. Authors of scientific research covering issues related to the impact of the family and the environment in which the family lives and functions on its members’ health in the present and in the future were encouraged to contribute their work. In addition, we were especially interested in scientific reports on social, economic, and health inequalities in the context of achieving the sustainable development goals.

Keywords

family --- living with children --- parenthood --- mother --- father --- self-rated health --- health behavior --- mental health --- Germany --- gut microbiome --- antimicrobial activity --- pathogen overgrowth --- smoking --- tobacco smoke --- exposure to tobacco smoke --- ETS --- anti-tobacco law --- hospitality venues --- quality of life --- the elderly --- seniors --- health --- cardiovascular diseases --- physical and psychological well-being --- health behaviors --- pregnancy --- rural area --- urban area --- CHEK2 --- MEN --- Cushing syndrome --- hypertension --- multiple endocrine glands tumors --- cervix uteri --- epidemiology --- screening --- mortality --- time trends --- east-central Europe --- depression --- bone markers --- osteocalcin --- β-CTX --- vitamin D --- metabolomics --- metabolites --- amino acids --- biomarkers --- asthma --- diagnosis --- children --- community health services --- postmodern education theories --- factor analysis --- genetic testing --- umbilical cord blood banking --- women health --- air pollution --- PM2.5 --- pregnancy outcomes --- sustainable development --- spatio-temporal data --- NUTS-1 --- kernel discriminant coordinates method --- super macroregions --- proteomics --- mass spectrometry --- MALDI-MSI --- tissue imaging --- ovarian tumors --- gestational diabetes mellitus --- diabetes --- obesity --- cesarean section --- health policy --- health inequalities --- healthcare access --- spatial distribution of the health situation --- cluster analysis --- functional discriminant coordinates --- multivariate functional coefficient of variation --- adenomyosis --- infertility --- GnRH --- in vitro fertilisation --- type 1 diabetes --- proteomic profile --- C4 complement --- PURE study --- noncommunicable diseases --- urban --- rural --- FRAP --- TBARS --- anaerobic threshold --- peakVO2 --- lifestyle --- training --- exercises --- intergenerational relations --- academic youth --- standardized questionnaire WHOQOL-BREF --- alcohol --- cohort study --- PURE --- pro-health behaviours --- anti-health behaviour --- prevention --- patient --- 50+ population --- chronic diseases --- special motor fitness --- speed --- flexibility --- endurance --- physical activity --- health training --- women --- WHOQOL-BREF questionnaire --- Bangladesh --- gender violence --- multidimensional poverty --- poverty reduction --- women’s empowerment --- color vision --- anomaloscope --- Moreland --- Rayleigh --- Hashimoto’s disease --- oxidative stress --- zinc --- copper --- child health --- child nutrition --- dairy --- food security --- food systems --- nutrition --- sustainability --- sustainable food systems --- working population --- Poland --- Ukraine --- spinal cord injury --- hematological parameters --- peak oxygen uptake --- sleep duration --- bedtime --- access to health care --- health care services --- hospital emergency departments --- spatial analysis --- public health management --- testosterone --- cortisol --- creatinine --- overtraining

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