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Ce travail de fin d’étude s’intéresse à la prise en charge de l’ostéoporose post-ménopausique et de ces différents traitements. Après une revue de la situation en termes de prévalence, de coût, de Femmes dépistage et diagnostic, ce travail décrira les différentes thérapies que Depistage sont entre autres: les compléments en calcium-vitamine D, les traitement biphosphonates, etc; ainsi qu’un chapitre important sur Ostéonécrose l’ostéonécrose de la mâchoire et le rôle du médecin généraliste Médecine générale comme acteur central dans la prise en charge de cette maladie à long terme.

Osteoporosis --- Postmenopause --- Diagnosis --- General Practice --- Osteonecrosis

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While many clinicians currently recognize that bisphosphonate usage is associated with osteonecrosis of the jaws, this book establishes the causal relationship between the two, explaining the biologic modes of action that enable bisphosphonates taken both orally and intravenously to induce osteonecrosis of the jaws. Like the first edition, it presents definitive treatment protocols for patients who present at each stage in the progression of osteonecrosis, but this new edition also includes a simplified staging system and information about the serum CTX test for oral bisphosphonate cases. In addition, several management principles and surgical techniques are provided, along with new data on osteopenia and osteoporosis, the conditions for which bisphosphonates are primarily prescribed. The book offers a simple method for predicting risk as well as crucial recommendations for preventing the disease from developing when bisphosphonate therapy is indicated. Comprehensive case histories related to both oral and intravenous bisphosphonates provide direct guidance in managing patients spanning the full presentation spectrum.

Osteonecrosis --- Jaw Diseases --- Drug-Related Side Effects and Adverse Reactions. --- Diphosphonates --- Osteonecrosis --- Jaw Diseases --- Diphosphonates --- Jaws --- Osteopetrosis --- Ostéonécrose --- Maxillaires --- Médicaments --- Diphosphonates. --- Maxillaires --- Ostéopétrose. --- therapy. --- therapy. --- adverse effects. --- etiology. --- etiology. --- Necrosis --- Étiologie. --- Maladies --- Étiologie. --- Effets secondaires. --- Nécroses.

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The present book recapitulates the articles published within the Special Issue "Cartilage Repair and Regeneration: Focus on Multi-Disciplinary Strategies", Applied Sciences, MDPI, dealing with the innovative multi-disciplinary therapeutic approaches for musculoskeletal diseases. In particular the published studies space from advanced 3D bioprinting technology to obtain a scaffold with different zonal cell densities, and biphasic scaffold (ChondroMimetic) construction, pass through the comparison of different techniques for cartilage regeneration such as of mosaicplasty and matrix-assisted autologous chondrocyte transplantation (MACT) and histopathological features of osteochondral units, and end with the considerations regarding development of bioreactors able to mimic the biomechanical load on chondrocytes in vitro, giving some interesting insights in this specific scientific field.

Medicine --- Pharmacology --- mesenchymal stem cells --- tissue engineering --- chondrogenesis --- osteoarthritis --- bioreactor --- mechanical stimuli --- physical stimulation --- compression --- shear stress --- hydrostatic pressure --- osteonecrosis --- osteochondral unit --- tissue remodelling and repair --- multi-targeted approach --- mosaicplasty --- MACT --- ACI --- scaffold --- osteochondral autologous transplantation --- OAT --- cartilage --- knee --- biphasic scaffold --- osteochondral defect --- cartilage repair --- quantitative MRI --- calcium phosphate --- bioprinting --- biofabrication --- articular cartilage --- human chondrocytes --- cell density --- cell gradient --- 3D bioprinting --- ChondroMimetic --- cartilage regeneration --- osteochondral repair --- matrix-assisted autologous chondrocyte transplantation --- magneto-responsive techniques --- biomechanical stimuli --- multi-disciplinary approach --- mesenchymal stem cells --- tissue engineering --- chondrogenesis --- osteoarthritis --- bioreactor --- mechanical stimuli --- physical stimulation --- compression --- shear stress --- hydrostatic pressure --- osteonecrosis --- osteochondral unit --- tissue remodelling and repair --- multi-targeted approach --- mosaicplasty --- MACT --- ACI --- scaffold --- osteochondral autologous transplantation --- OAT --- cartilage --- knee --- biphasic scaffold --- osteochondral defect --- cartilage repair --- quantitative MRI --- calcium phosphate --- bioprinting --- biofabrication --- articular cartilage --- human chondrocytes --- cell density --- cell gradient --- 3D bioprinting --- ChondroMimetic --- cartilage regeneration --- osteochondral repair --- matrix-assisted autologous chondrocyte transplantation --- magneto-responsive techniques --- biomechanical stimuli --- multi-disciplinary approach

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The present book recapitulates the articles published within the Special Issue "Cartilage Repair and Regeneration: Focus on Multi-Disciplinary Strategies", Applied Sciences, MDPI, dealing with the innovative multi-disciplinary therapeutic approaches for musculoskeletal diseases. In particular the published studies space from advanced 3D bioprinting technology to obtain a scaffold with different zonal cell densities, and biphasic scaffold (ChondroMimetic) construction, pass through the comparison of different techniques for cartilage regeneration such as of mosaicplasty and matrix-assisted autologous chondrocyte transplantation (MACT) and histopathological features of osteochondral units, and end with the considerations regarding development of bioreactors able to mimic the biomechanical load on chondrocytes in vitro, giving some interesting insights in this specific scientific field.

mesenchymal stem cells --- tissue engineering --- chondrogenesis --- osteoarthritis --- bioreactor --- mechanical stimuli --- physical stimulation --- compression --- shear stress --- hydrostatic pressure --- osteonecrosis --- osteochondral unit --- tissue remodelling and repair --- multi-targeted approach --- mosaicplasty --- MACT --- ACI --- scaffold --- osteochondral autologous transplantation --- OAT --- cartilage --- knee --- biphasic scaffold --- osteochondral defect --- cartilage repair --- quantitative MRI --- calcium phosphate --- bioprinting --- biofabrication --- articular cartilage --- human chondrocytes --- cell density --- cell gradient --- 3D bioprinting --- ChondroMimetic --- cartilage regeneration --- osteochondral repair --- matrix-assisted autologous chondrocyte transplantation --- magneto-responsive techniques --- biomechanical stimuli --- multi-disciplinary approach

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The dental curriculum is like a living organism—it has developed through time, manifesting regional, cultural, and scientific heritage, and reflecting modern trends. The undergraduate dental curriculum is periodically rebuilt to ensure the harmonization of higher education systems between countries, especially in Europe. Structure, content, learning, and assessment in undergraduate and postgraduate dental education and auxiliary dental personnel training are shaped based on professional consensus. Constant updates on recent technological innovations and evidence-based best practice are necessary.In modern times, ethical issues are raised more than ever. Can we teach our students how to be dedicated health professionals and manage a successful practice at the same time? Does the commercialization of our profession also affect the dental curriculum today?The COVID-19 pandemic has imposed new challenges, moving us from lecture rooms and clinics to an online environment.This Special Issue is dedicated to developing the understanding of dental education.

Humanities --- Social interaction --- educational climate --- dental students --- DREEM scale --- dental education --- dentistry --- dental hygienists --- job satisfaction --- work assignments --- workplace environment --- Japan --- healthy lifestyle --- surveys and questionnaires --- health behavior --- health promotion --- school health services --- dental record --- record keeping --- documentation --- forensic odontology --- Croatia --- medication-related osteonecrosis of the jaw --- fracture --- mandible --- osteonecrosis --- bisphosphonates --- undergraduate dental education --- postgraduate dental education --- continuing education --- professionalism in dentistry --- online education --- digital media --- social media --- perceived risks --- dental hygiene --- oral pathology --- exam soft --- item analysis --- mentoring --- non-technical skills training --- motor skills --- learning theories --- self-consciousness --- working memory --- visual acuity --- miniaturized Snellen optotype --- Galilean and Keplerian telescope optical system in dentistry --- clinical skills teaching --- teaching methodology --- local anesthesia --- clinical education --- early clinical experience --- motivation --- stress perceptions --- self-determination theory --- self-efficacy --- social learning theory --- Dietary Guidelines for Americans (DGA) --- diet --- dental student --- education --- dental hygiene education --- educational technology --- classification consistency --- oral lesion --- biomedical sciences --- vertical integration --- curriculum reform --- interprofessional learning --- virdentopsy --- virtual dental autopsy --- autopsy imaging --- human identification --- dental autopsy --- humanitarian forensic odontology --- dental caries --- diagnosis --- online learning --- COVID-19 --- composite restoration --- conservative dentistry --- operative dentistry --- undergraduate dental student --- dentin bonding --- virtual reality --- haptics --- simulation --- Simodont --- dental care --- oncology --- chemotherapy --- radiotherapy --- osteoradionecrosis --- specialty training --- student survey --- knowledge-based governance --- curriculum --- dental --- graduate --- dental continuing --- teacher training --- educational climate --- dental students --- DREEM scale --- dental education --- dentistry --- dental hygienists --- job satisfaction --- work assignments --- workplace environment --- Japan --- healthy lifestyle --- surveys and questionnaires --- health behavior --- health promotion --- school health services --- dental record --- record keeping --- documentation --- forensic odontology --- Croatia --- medication-related osteonecrosis of the jaw --- fracture --- mandible --- osteonecrosis --- bisphosphonates --- undergraduate dental education --- postgraduate dental education --- continuing education --- professionalism in dentistry --- online education --- digital media --- social media --- perceived risks --- dental hygiene --- oral pathology --- exam soft --- item analysis --- mentoring --- non-technical skills training --- motor skills --- learning theories --- self-consciousness --- working memory --- visual acuity --- miniaturized Snellen optotype --- Galilean and Keplerian telescope optical system in dentistry --- clinical skills teaching --- teaching methodology --- local anesthesia --- clinical education --- early clinical experience --- motivation --- stress perceptions --- self-determination theory --- self-efficacy --- social learning theory --- Dietary Guidelines for Americans (DGA) --- diet --- dental student --- education --- dental hygiene education --- educational technology --- classification consistency --- oral lesion --- biomedical sciences --- vertical integration --- curriculum reform --- interprofessional learning --- virdentopsy --- virtual dental autopsy --- autopsy imaging --- human identification --- dental autopsy --- humanitarian forensic odontology --- dental caries --- diagnosis --- online learning --- COVID-19 --- composite restoration --- conservative dentistry --- operative dentistry --- undergraduate dental student --- dentin bonding --- virtual reality --- haptics --- simulation --- Simodont --- dental care --- oncology --- chemotherapy --- radiotherapy --- osteoradionecrosis --- specialty training --- student survey --- knowledge-based governance --- curriculum --- dental --- graduate --- dental continuing --- teacher training