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Swine --- Osteochondrosis. --- Joints --- Joints --- Osteochondrosis. --- Swine --- Diseases. --- Diseases. --- Diseases. --- Diseases.

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L’ostéochondrose est une maladie orthopédique de développement fréquemment décrite chez l’homme et chez plusieurs espèces d’animaux domestiques. Sa prévalence élevée au sein de la population équine a un impact économique non négligeable dans le domaine du sport, par ses répercussions cliniques, et dans le domaine de l’élevage, par la suspicion d’un facteur héréditaire. Cette pathologie est définie comme une non-ossification endochondrale des épiphyses pouvant mener à la formation de kystes et de fragments ostéo-chondraux (ostéochondrose dissécante). On sait aujourd’hui que la pathogénie repose sur une nécrose ischémique focale des chondrocytes au niveau de sites de prédilection bien définis. C’est une maladie à caractère dynamique puisqu’une régression et une guérison spontanée des lésions est possible durant la première année de vie. L’étiologie exacte de l’ostéochondrose reste à ce jour non élucidée mais il est admis qu’il s’agirait d’un problème complexe et multifactoriel impliquant des facteurs génétiques, environnementaux, endocriniens et biomécaniques. Un lien entre le développement de l’ostéochondrose chez le jeune cheval et ses conditions environnementales, comme l’alimentation, le type d’hébergement et le degrés d’exercice à des moments clés, comme la gestation et les premiers mois de vie, a clairement été établi. La croissance intra-utérine et en particulier le début de l’ossification endochondrale pourrait être modulée par la nutrition de la jument gestante, ce qui souligne le rôle du métabolisme énergétique dans l’étiologie de la maladie. De récentes études ont identifié plusieurs voies de signalisation cellulaire dont l’altération pourrait être liée à l’apparition de cette pathologie. Parmi elles, la voie signalétique Wnt/β-caténine semble être un régulateur majeur de l’activité osseuse et pourrait être directement reliée au développement de lésions d’ostéochondrose. La compréhension du rôle des différents facteurs environnementaux dans l’apparition de la maladie représente un enjeu de taille pour la mise en place de nouvelles stratégies de diagnostic et de prévention.

osteochondrosis, horse, OCD, environment --- Sciences du vivant > Médecine vétérinaire & santé animale

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This book addresses hot topics relating to talar osteochondritis dissecans (OCD): improvements in the accuracy of diagnosis, sound preoperative planning, optimal treatment, and procedure-specific rehabilitation protocols. The technical difficulties in each of these areas are identified and evidence-based guidelines are presented. With regard to diagnosis, several chapters discuss the roles of arthroscopy, standard radiography, computed tomography, magnetic resonance imaging, and combined imaging modalities (PET/CT and SPECT/CT). The chapters on treatment cover various surgical options and provide an overview of the direct postoperative treatment; in addition, rehabilitation protocols are described for all the treatment procedures.   The book has been written by a team of leading experts in the field of foot and ankle surgery from across the globe who have aimed to provide the reader with an up-to-date handbook ideal for use when approaching a patient with a talar OCD. Their reviews and opinions are based firmly on the best currently available evidence.

Ankle --- Osteochondrosis. --- Wounds and injuries. --- Epiphyseal ischemic necrosis --- Osteochondritis --- Bones --- Necrosis --- Orthopedic surgery. --- Sports medicine. --- Physiotherapy. --- Rehabilitation. --- Surgical Orthopedics. --- Sports Medicine. --- Athletic medicine --- Athletics --- Medicine and sports --- Physical education and training --- Sports --- Medicine --- Sports sciences --- Operative orthopedics --- Orthopedics --- Surgery, Operative --- Medical aspects --- Orthopedics. --- Orthopaedics --- Orthopedia --- Surgery

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Osteoporosis is one of the ten most important diseases worldwide and its importance will rise further f- lowing the aging of the population. Vertebral fractures are the most common fractures in osteoporosis and have signi?cant impact on quality of life and survival rates, as well as carrying increased socioeconomic costs. The establishment of minimally invasive treatment schemes in recent years has led to reduced peri- erative morbidity and increased early mobilization. This book focuses on balloon kyphoplasty and alter- tive minimally invasive treatments for stabilization of osteoporotic vertebral fractures. The optimal treatment of a patient with osteoporotic vertebral fractures requires an interdisciplinary - proach, and therefore our book draws on the expertise of orthopedic surgeons, traumatologists and neu- surgeons, and also includes a chapter on medical treatment. We are happy to present the ?rst English edition of this book. All chapters have been extensively revised and updated. In addition to a detailed description of the technique of balloon kyphoplasty, with practical tips from experts, the book retains a chapter on the medical treatment of osteoporosis, which is still ind- pensable in the interdisciplinary approach to osteoporosis. This well established concept, uniting several treatment aspects including conservative treatment, is preserved in this book. However, new chapters have been added as the result of recent developments and clinical ?ndings.

Fractures -- Treatment. --- Kyphosis. --- Spine -- Abnormalities. --- Spine -- Surgery. --- Vertebrae -- Fractures. --- Vertebrae --- Spine --- Bone Diseases, Metabolic --- Spinal Injuries --- Fractures, Bone --- Orthopedic Procedures --- Spinal Curvatures --- Spinal Diseases --- Therapeutics --- Wounds and Injuries --- Back Injuries --- Surgical Procedures, Operative --- Bone Diseases --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Diseases --- Musculoskeletal Diseases --- Osteoporosis --- Kyphosis --- Spinal Fractures --- Vertebroplasty --- Surgery & Anesthesiology --- Health & Biological Sciences --- Surgery - General and By Type --- Fractures --- Surgery --- Abnormalities --- Fractures. --- Abnormalities. --- Surgery. --- Treatment. --- Spinal osteochondrosis --- Vertebral osteochondrosis --- Abnormities and deformities --- Medicine. --- Interventional radiology. --- Rheumatology. --- Neurosurgery. --- Orthopedics. --- Traumatology. --- Surgical oncology. --- Medicine & Public Health. --- Surgical Orthopedics. --- Surgical Oncology. --- Interventional Radiology. --- Traumatic Surgery. --- Posture disorders --- Orthopedic surgery. --- Trauma. --- Nerves --- Neurosurgery --- Internal medicine --- Connective tissues --- Joints --- Radiology, Interventional --- Medical radiology --- Cancer --- Oncologic surgery --- Oncological surgery --- Surgical oncology --- Operative orthopedics --- Orthopedics --- Surgery, Operative --- Excision --- Treatment --- Interventional radiology . --- Accident medicine --- Trauma medicine --- Emergency medicine --- Wounds and injuries --- Orthopaedics --- Orthopedia