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Opiate drugs are high-risks drugs, subjects to a high percentage of errors and adverse effects that can have serious or even fatal consequences on the health of treated patients. Therefore, special precautions must be taken to improve the safety and circulation of these medicines in hospitals. The pharmaco-therapeutic process is very complex and may include multiple errors in drug history, individualization of treatment, prescription of an order, transcription or interpretation of the prescription, preparation of the drug(s), delivery, administration, monitoring and therapeutic follow-up. Based on the literature and the answers collected by interviewing Belgian hospital pharmacists, we have identified numerous strategies and leads for improvement that could increase vigilance regarding the opiate circuit in hospitals. Les médicaments opiacés sont des médicaments à haut risque, sujets à un grand pourcentage d'erreurs et d'effets indésirables pouvant avoir des conséquences graves voire fatales sur la santé des patients traités. De ce fait, des précautions particulières doivent être prises afin d'améliorer la sécurité et le circuit de ces médicaments en milieu hospitalier. Le processus pharmaco-thérapeutique est très complexe et peut comprendre des multiples erreurs au niveau de l'historique médicamenteux, de l'individualisation du traitement, de la prescription d'une ordonnance, de la transcription ou l'interprétation de l'ordonnance, de la préparation du (des) médicament(s), de la délivrance, de l’administration, du monitoring ainsi que du suivi thérapeutique. Sur base de la littérature et des réponses collectées en interrogeant les pharmaciens hospitaliers belges, nous avons identifié des nombreuses stratégies et pistes d'amélioration qui pourraient accroitre la vigilance concernant le circuit d'opiacés en milieu hospitalier.

Opioid-Related Disorders --- Drug Storage --- Medication Errors

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Outside back cover : "Gain vital guidance and support when treating the high-risk, high-reward population of women confronting (or battling) opioid-use disorders during pregnancy. Large numbers of pregnant women are dependent on opioids and require comprehensive non-judgemental care to replace traditional approaches of incarceration and child welfare involvement that worsen outcomes for both mother and infant. Invaluable and comprehensive, this toolkit provides the key to non-judgemental care for both mother and baby, throughout labor, delivery management and postpartum care. Bridge the important treatment gap through this evidence-based, caring approach; standardizing exceptional care, for obstetricians, pediatricians, addictionists, and anyone caring for pregnant women with opioid-use disorders. Edited by a Board-certified expert in Obstetrics, Gynecology and Addiction Medicine, and a team of internationally-acclaimed leaders in Women’s Health, this guide provides high-quality advice, guidelines and vital skills to tackle a currently expanding, opioid epidemic"

Opioid-Related Disorders --- Pregnant Women --- Prenatal Care --- Postnatal Care --- Pregnancy

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Opium abuse. --- Opium. --- Morphine. --- Opioid-Related Disorders. --- Substance-Related Disorders.

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A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Opioids, Volume 4 in the series, explores the molecular, cellular and systems in the brain responsible for opioid addiction using the heuristic three-stage cycle framework of binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation.

Opioid abuse. --- Drug abuse --- Opioids --- Physiological effect. --- Opioid-Related Disorders --- Nervous System --- physiopathology --- Opioid-Related Disorders. --- physiopathology.

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Medicine --- Clinical medicine --- Decision making --- Opioid-related disorders --- history --- ethics --- therapy