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Harnessing the potential of the human body's own immune system to attack malignant tumor cells has been the goal of many scientific investigators in recent years, with advances in cancer biology and immunology enabling cancer immunotherapy to become a reality. World-class bench and clinical researchers have joined forces to collaborate and review current developments and trends in cancer immunology for the purposes of this book, and the result is a promising review of contemporary clinical treatments. In each chapter the authors present the scientific basis behind such therapeutic approaches, including cancer vaccines with special focus on prostate cancer, melanoma and novel approaches utilizing both innate and adaptive immune responses.
Cancer vaccines. --- Oncologic vaccines --- Oncology vaccines --- Neoplasm vaccines --- Tumor vaccines --- Vaccines --- Oncology
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Cervical cancer is the second most common form of cancer found in women and it is responsible for more than a quarter of a million deaths worldwide each year. With approximately 70% of cervical cancers now known to be caused by two types of the human papilloma virus (HPV), there is great interest surrounding the approval of the first preventative vaccines for clinical use. Despite this excitement, many questions remain about how the new vaccines should best be implemented and how cervical cancer screening will change following vaccination.Part of the Oxford Oncology Library series, this practice
Cervix uteri --- Cancer vaccines. --- Oncologic vaccines --- Oncology vaccines --- Neoplasm vaccines --- Tumor vaccines --- Vaccines --- Cancer --- Prevention.
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Nanomedicine. --- Cancer vaccines. --- Oncologic vaccines --- Oncology vaccines --- Neoplasm vaccines --- Tumor vaccines --- Vaccines --- Medicine --- Nanotechnology
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Vaccines --- Vaccines. --- oncology vaccines --- AIDS vaccine --- vaccine safety --- vaccine formulation --- vaccine adjuvants --- veterinary vaccines --- aids vaccine --- Oncology. Neoplasms --- Allergy
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This volume focuses on the laboratory and clinical experience with targeting viral onco-antigens, while also reviewing the approaches to targeting self-cancer antigens in cancers of non-viral origin, where self-tolerance has been a challenge. It emphasizes the importance of selecting the right vaccine platform to induce a successful immune response against cancer antigens. In addition, the volume discusses the advances made with genetic vaccines, including recent advances with DNA vaccines and the rapid transition of mRNA vaccines from the laboratory to bedside. The new avenues opening up for cancer immunotherapy underline the importance of combinational approaches using cancer vaccines with costimulatory antibodies, which may dramatically improve cancer treatment. This book is intended for all translational researchers and clinicians who aspire to develop novel vaccination approaches for cancer patients with unmet clinical needs.
Cancer vaccines. --- Oncologic vaccines --- Oncology vaccines --- Neoplasm vaccines --- Tumor vaccines --- Medicine. --- Cancer research. --- Immunology. --- Vaccines. --- Biomedicine. --- Cancer Research. --- Vaccine. --- Biologicals --- Immunobiology --- Life sciences --- Serology --- Cancer research --- Clinical sciences --- Medical profession --- Human biology --- Medical sciences --- Pathology --- Physicians --- Vaccines --- Oncology. --- Tumors
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It all started with an observation. Edward Jenner, an English physician, observed that milkmaids who contracted cowpox were rarely victims of smallpox epidemic, a disease that in?icted a heavy toll on humankind with an estimate of 500 million victimsworldwide.In1796,Jennerinoculatedtheextracted?uidfromblistersonthe handofamilkmaidwhowasinfectedwithcowpoxintothearman8yearoldpeasant boy. After the boy recovered from a mild illness caused by this inoculation, Jenner exposed him to smallpox and to his delight the boy did not develop the disease. He published his work in 1798 in three publications titled “Vaccination Against smallpox”, where the term vaccination is derived from the Latin word “vacca” meaning cow. Jenner was recognized to be the father of modern immunology, and hisworkmarkedthecommencementofanewdawninmedicinethatledtothe1979 declaration by the World Health Organization (WHO) of the global eradication of smallpox. By the beginning of the 20th century, vaccines for typhoid fever, rabies, polio, plaque and diphtherias were in use, and nowadays we are equipped with effectivevaccinesagainstmorethan20infectiousdiseasessuchasmeningitis,rubella, whooping cough, rabies, and hepatitis B among others.
Cancer Vaccines. --- Neoplasms --- Antigens, Neoplasm. --- Tumors --- Cancer vaccines. --- Tumeurs --- Vaccins anticancéreux --- immunology. --- Immunological aspects. --- Immunologie --- Tumors - Immunological aspects. --- Cancer vaccines --- Cancer Vaccines --- Antigens, Neoplasm --- Diseases --- Antigens --- Vaccines --- Biological Products --- Biological Factors --- Complex Mixtures --- Chemicals and Drugs --- Oncology --- Microbiology & Immunology --- Medicine --- Biology --- Health & Biological Sciences --- Immunological aspects --- Oncologic vaccines --- Oncology vaccines --- Neoplasm vaccines --- Tumor vaccines --- Tumor immunology --- Medicine. --- Oncology. --- Medicine & Public Health. --- Oncology .
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