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Neuroimmunity is a relative new and rapidly expanding area of interest that critically impacts normal brain function and a wide range of neurological disorders. Neuroimmune mechanisms operate within the nervous system and between the nervous system and periphery. Glial cells of the nervous system play a primary role in neuroimmunity, through their ability to produce and respond to neuroimmune signaling factors, which serve a number of functions, such as homeostatic regulation of nervous system function and defense against insult and infection. Dysfunction of the neuroimmune system is now thought to be an important contributing factor to many disease and injury states. The purpose of this Special Issue is to provide a representative view of current research in this growing field, with an emphasis on the central nervous system.
cytokine --- neuroimmune --- chemokine --- neurodevelopment --- neurologic disease --- neuronal injury --- glia cell --- neuron --- neuroimmune disorder --- psychiatric disease
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Neuroimmunology --- Neuro-immunologie --- Neuroimmunology. --- Neuro-immunologie. --- Immune System --- Nervous System --- Neuroimmunomodulation. --- physiology. --- immunology. --- Neuroimmune Mechanisms --- Neuroimmune Process --- Neuroimmune Processes --- Mechanism, Neuroimmune --- Mechanisms, Neuroimmune --- Neuroimmune Mechanism --- Process, Neuroimmune --- Neuroimmunomodulation --- Homeostasis --- Neurosecretory Systems --- Psychoneuroimmunology --- Neurogenic Inflammation --- Immunology --- Neurosciences --- physiology --- immunology --- Nervous Systems --- System, Nervous --- Systems, Nervous --- Immune Systems --- System, Immune --- Systems, Immune --- Cholinergic Anti-inflammatory Pathway --- Neuro-immune Axis --- Neuro-immune Communication --- Neuro-immune Interactions --- Neuro-immunomodulation --- Neuroimmune Axis --- Neuroimmune Communication --- Neuroimmune Interactions --- Vagal Anti-inflammatory Pathway --- Vagal-immune Interactions --- Anti-inflammatory Pathway, Cholinergic --- Anti-inflammatory Pathway, Vagal --- Cholinergic Anti inflammatory Pathway --- Cholinergic Anti-inflammatory Pathways --- Communication, Neuro-immune --- Communication, Neuroimmune --- Interaction, Neuro-immune --- Interaction, Neuroimmune --- Neuro immune Axis --- Neuro immune Communication --- Neuro immune Interactions --- Neuro immunomodulation --- Neuro-immune Communications --- Neuro-immune Interaction --- Neuroimmune Communications --- Neuroimmune Interaction --- Vagal Anti inflammatory Pathway --- Vagal Anti-inflammatory Pathways --- Vagal immune Interactions --- Vagal-immune Interaction
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Neuroimmunomodulation. --- Neuroimmune Mechanisms --- Neuroimmune Process --- Neuroimmune Processes --- Mechanism, Neuroimmune --- Mechanisms, Neuroimmune --- Neuroimmune Mechanism --- Process, Neuroimmune --- Homeostasis --- Neurosecretory Systems --- Psychoneuroimmunology --- Neurogenic Inflammation --- Periodicals --- Neuroimmunology --- Health Sciences --- Life Sciences --- General and Others --- Physiology --- Cytology, Cell Biology --- Genetics --- Immunology --- Micro and Molecular Biology --- Cholinergic Anti-inflammatory Pathway --- Neuro-immune Axis --- Neuro-immune Communication --- Neuro-immune Interactions --- Neuro-immunomodulation --- Neuroimmune Axis --- Neuroimmune Communication --- Neuroimmune Interactions --- Vagal Anti-inflammatory Pathway --- Vagal-immune Interactions --- Anti-inflammatory Pathway, Cholinergic --- Anti-inflammatory Pathway, Vagal --- Cholinergic Anti inflammatory Pathway --- Cholinergic Anti-inflammatory Pathways --- Communication, Neuro-immune --- Communication, Neuroimmune --- Interaction, Neuro-immune --- Interaction, Neuroimmune --- Neuro immune Axis --- Neuro immune Communication --- Neuro immune Interactions --- Neuro immunomodulation --- Neuro-immune Communications --- Neuro-immune Interaction --- Neuroimmune Communications --- Neuroimmune Interaction --- Vagal Anti inflammatory Pathway --- Vagal Anti-inflammatory Pathways --- Vagal immune Interactions --- Vagal-immune Interaction --- Neuroimmunomodulation
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Neuroimmunology --- Neuroimmunomodulation --- Neuroimmunomodulation. --- Neuroimmunology. --- Neuroimmunologie. --- Zeitschrift. --- Online-Publikation. --- Immunology --- Neurosciences --- Neuroimmune Mechanisms --- Neuroimmune Process --- Neuroimmune Processes --- Mechanism, Neuroimmune --- Mechanisms, Neuroimmune --- Neuroimmune Mechanism --- Process, Neuroimmune --- Homeostasis --- Neurosecretory Systems --- Psychoneuroimmunology --- Neurogenic Inflammation --- Neuroimmunologie --- Zeitschrift --- Online-Ressource --- Cholinergic Anti-inflammatory Pathway --- Neuro-immune Axis --- Neuro-immune Communication --- Neuro-immune Interactions --- Neuro-immunomodulation --- Neuroimmune Axis --- Neuroimmune Communication --- Neuroimmune Interactions --- Vagal Anti-inflammatory Pathway --- Vagal-immune Interactions --- Anti-inflammatory Pathway, Cholinergic --- Anti-inflammatory Pathway, Vagal --- Cholinergic Anti inflammatory Pathway --- Cholinergic Anti-inflammatory Pathways --- Communication, Neuro-immune --- Communication, Neuroimmune --- Interaction, Neuro-immune --- Interaction, Neuroimmune --- Neuro immune Axis --- Neuro immune Communication --- Neuro immune Interactions --- Neuro immunomodulation --- Neuro-immune Communications --- Neuro-immune Interaction --- Neuroimmune Communications --- Neuroimmune Interaction --- Vagal Anti inflammatory Pathway --- Vagal Anti-inflammatory Pathways --- Vagal immune Interactions --- Vagal-immune Interaction --- Netzpublikation --- Online-Publikation --- Computerdatei im Fernzugriff --- Online-Dokument --- On-line-Dokument --- On-line-Publikation --- Elektronische Publikation --- Periodikum --- Zeitschriften --- Presse --- Fortlaufendes Sammelwerk --- Immunoneurologie --- Immunologie --- Neurologie
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Neuroimmunology --- Neuroimmunomodulation. --- Neurogenic Inflammation. --- Neuroimmunology. --- Neuroimmunomodulation --- Immunology --- Neurosciences --- Inflammation, Neurogenic --- Inflammations, Neurogenic --- Neurogenic Inflammations --- Neuroimmune Mechanisms --- Neuroimmune Process --- Cholinergic Anti-inflammatory Pathway --- Neuro-immune Axis --- Neuro-immune Communication --- Neuro-immune Interactions --- Neuro-immunomodulation --- Neuroimmune Axis --- Neuroimmune Communication --- Neuroimmune Interactions --- Neuroimmune Processes --- Vagal Anti-inflammatory Pathway --- Vagal-immune Interactions --- Anti-inflammatory Pathway, Cholinergic --- Anti-inflammatory Pathway, Vagal --- Cholinergic Anti inflammatory Pathway --- Cholinergic Anti-inflammatory Pathways --- Communication, Neuro-immune --- Communication, Neuroimmune --- Interaction, Neuro-immune --- Interaction, Neuroimmune --- Mechanism, Neuroimmune --- Neuro immune Axis --- Neuro immune Communication --- Neuro immune Interactions --- Neuro immunomodulation --- Neuro-immune Communications --- Neuro-immune Interaction --- Neuroimmune Communications --- Neuroimmune Interaction --- Neuroimmune Mechanism --- Process, Neuroimmune --- Vagal Anti inflammatory Pathway --- Vagal Anti-inflammatory Pathways --- Vagal immune Interactions --- Vagal-immune Interaction --- Homeostasis --- Neurosecretory Systems --- Psychoneuroimmunology --- Neurogenic Inflammation --- neurology
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Psychoneuroimmunology --- Neuroimmunology --- Neuroimmunology. --- Psychoneuroimmunology. --- Neuroimmunomodulation. --- Psychoimmunology --- Psychoneuroimmunoendocrinology --- Neuroimmunomodulation --- Immunology --- Neurosciences --- Neuroimmune Mechanisms --- Neuroimmune Process --- Cholinergic Anti-inflammatory Pathway --- Neuro-immune Axis --- Neuro-immune Communication --- Neuro-immune Interactions --- Neuro-immunomodulation --- Neuroimmune Axis --- Neuroimmune Communication --- Neuroimmune Interactions --- Neuroimmune Processes --- Vagal Anti-inflammatory Pathway --- Vagal-immune Interactions --- Anti-inflammatory Pathway, Cholinergic --- Anti-inflammatory Pathway, Vagal --- Cholinergic Anti inflammatory Pathway --- Cholinergic Anti-inflammatory Pathways --- Communication, Neuro-immune --- Communication, Neuroimmune --- Interaction, Neuro-immune --- Interaction, Neuroimmune --- Mechanism, Neuroimmune --- Neuro immune Axis --- Neuro immune Communication --- Neuro immune Interactions --- Neuro immunomodulation --- Neuro-immune Communications --- Neuro-immune Interaction --- Neuroimmune Communications --- Neuroimmune Interaction --- Neuroimmune Mechanism --- Process, Neuroimmune --- Vagal Anti inflammatory Pathway --- Vagal Anti-inflammatory Pathways --- Vagal immune Interactions --- Vagal-immune Interaction --- Homeostasis --- Neurosecretory Systems --- Neurogenic Inflammation --- cognition --- perception --- emotion --- personality --- psychoneuroimmunology
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The brain and immune system are involved in an intricate network of bidirectional communication. This relationship is vital for optimal physiological and psychological development and functioning but can also result in unwanted outcomes. In particular, this interaction plays an important role in cognition, mood and behaviour. Neuroinflammation is known to contribute to neurological and affective disorders including impaired learning and memory, depressive, anxiety and schizoaffective symptoms, as well as pain. The development of these conditions often occurs on the backdrop of pre-existing physical illnesses which give rise to increased activation of the immune system, such as cancer, obesity, infection and autoimmune disorders. Similarly, psychological states can alter regulation of the immune system. This has been most extensively studied in the context of stress and immune function. Understanding the underlying mechanisms that lead to the onset of inflammation-induced neuropathology and stress-induced immune suppression will lead to the development of novel and effective treatment strategies for both the disease and its neurological side effects. The aim of this research topic is to explore the relationship between the immune system and the brain throughout life from the developing infant to the ageing individual.
Neuroimmunology. --- Nervous system --- Nervous System Diseases --- neuroimmune --- Obesity --- neuroendocrine --- proinflammatory --- Aging --- Neuroinflammation --- Depression --- Mood Disorders --- Microglia --- Perinatal programming --- Diseases --- Immunological aspects. --- immunology. --- neuroimmune --- Obesity --- neuroendocrine --- proinflammatory --- Aging --- Neuroinflammation --- Depression --- Mood Disorders --- Microglia --- Perinatal programming
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The brain and immune system are involved in an intricate network of bidirectional communication. This relationship is vital for optimal physiological and psychological development and functioning but can also result in unwanted outcomes. In particular, this interaction plays an important role in cognition, mood and behaviour. Neuroinflammation is known to contribute to neurological and affective disorders including impaired learning and memory, depressive, anxiety and schizoaffective symptoms, as well as pain. The development of these conditions often occurs on the backdrop of pre-existing physical illnesses which give rise to increased activation of the immune system, such as cancer, obesity, infection and autoimmune disorders. Similarly, psychological states can alter regulation of the immune system. This has been most extensively studied in the context of stress and immune function. Understanding the underlying mechanisms that lead to the onset of inflammation-induced neuropathology and stress-induced immune suppression will lead to the development of novel and effective treatment strategies for both the disease and its neurological side effects. The aim of this research topic is to explore the relationship between the immune system and the brain throughout life from the developing infant to the ageing individual.
Neuroimmunology. --- Nervous system --- Nervous System Diseases --- Diseases --- Immunological aspects. --- immunology. --- neuroimmune --- Obesity --- neuroendocrine --- proinflammatory --- Aging --- Neuroinflammation --- Depression --- Mood Disorders --- Microglia --- Perinatal programming
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The term “synaptic plasticity” is a broad concept, which is studied with a variety of experimental approaches. One focus is the impact of changes in synaptic, neuronal and glial morphology on brain circuitry and behavior. In this regard, unique animal models have been key to the study of affective and social behaviors and neurological and psychiatric diseases. However, there is a paucity of compilations directed toward the correlation of alterations in synaptic structure with various physiological and behavioral paradigms. This Frontiers Research Topic will, therefore, serve as an exciting forum for the exchange of novel hypotheses and data and an important resource and reference for investigators studying synaptic and brain plasticity, as well as those in related fields.
Synaptic Function --- dendritic spine function --- neural circuits and behavior --- synaptic remodeling --- dendritic spine structure --- neuroimmune interactions --- Synaptic Transmission --- sexual dimorphism --- psychiatric disorders
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The brain and immune system are involved in an intricate network of bidirectional communication. This relationship is vital for optimal physiological and psychological development and functioning but can also result in unwanted outcomes. In particular, this interaction plays an important role in cognition, mood and behaviour. Neuroinflammation is known to contribute to neurological and affective disorders including impaired learning and memory, depressive, anxiety and schizoaffective symptoms, as well as pain. The development of these conditions often occurs on the backdrop of pre-existing physical illnesses which give rise to increased activation of the immune system, such as cancer, obesity, infection and autoimmune disorders. Similarly, psychological states can alter regulation of the immune system. This has been most extensively studied in the context of stress and immune function. Understanding the underlying mechanisms that lead to the onset of inflammation-induced neuropathology and stress-induced immune suppression will lead to the development of novel and effective treatment strategies for both the disease and its neurological side effects. The aim of this research topic is to explore the relationship between the immune system and the brain throughout life from the developing infant to the ageing individual.
Neuroimmunology. --- Nervous system --- Nervous System Diseases --- Diseases --- Immunological aspects. --- immunology. --- neuroimmune --- Obesity --- neuroendocrine --- proinflammatory --- Aging --- Neuroinflammation --- Depression --- Mood Disorders --- Microglia --- Perinatal programming
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