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This Special Issue covers both the in vitro and in vivo evaluation of marine carotenoids with anti-inflammatory and anticancer activities as well as clinical trials conducted in humans. Among the properties of carotenoids discussed in this book, it is worth highlighting the potential of astaxanthin and its precursor metabolite, adonixanthin, since oral administration of these carotenoids has shown beneficial effects on glioblastoma for the first time by suppressing cell proliferation and migration. In addition, astaxanthin has been shown to inhibit Helicobacter pylori-induced gastric carcinoma cell motility and, consequently, cancer progression through the inhibition of cytoskeleton reorganization. In addition, a carotenoid-containing lipid extract of Gloeothece sp. has demonstrated antioxidant, anti-inflammatory, and anticancer properties in vitro.

Helicobacter pylori --- gastric carcinoma --- astaxanthin --- cell motility --- cell migration --- bioavailability --- carotenoids --- marine --- nanoformulation --- oxidative stress --- reactive oxygen species --- brain --- cancer --- oral administration --- paracoccsu carotinifaciens --- xanthophyll carotenoid --- photodamage --- skin cancer --- photoaging --- marine carotenoids --- fucoxanthin --- xanthophylls --- natural compounds --- algae --- bioactive --- health --- neuroprotective agent --- neuroinflammation --- neurological diseases --- microalgae --- inflammation --- breast cancer --- bacterioruberin --- antioxidant --- pro-oxidant --- lutein --- β-carotene --- linolenic acid --- linoleic acid --- lipidic compounds --- PUFAs

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Nutritional deficiencies, and different nutritional and dietary lifestyles, whether poor or absent of essential nutrients, aside from excess intake, can lead to inflammatory complications and loss of function. Bioactive compounds are non-nutritional components derived from plants, foods, and beverages with a multitude of biological effects. The improvement of analytical techniques has allowed scientific community to state that the regular consumption of bioactive phytochemicals is related to the prevention of numerous pathologies, through mechanisms that involve oxidative stress reduction, gene expression modulation, and even enzymatic activation inhibition.

quercetin --- nervous system --- molecular signals --- pharmacological potential --- cognitive impairment. --- micronuclei --- radioprotectors --- radiation effects --- melanoma --- PNT2 --- B16F10 cells --- Ulmus parvifolia --- wound healing --- matrix metalloproteinase --- transforming growth factor --- skin rejuvenation --- kaempferol --- naringin --- orientin --- rutin --- vitexin --- chlorogenic acid --- citric acid --- malic acid --- quinic acid --- rosmarinic acid --- curcumin --- nanocurcumin --- neurological disorders --- nanocarriers --- liposomes --- cancer --- diet --- flavonoids --- food supplements --- hormesis --- phytoestrogens --- sulforaphane --- resveratrol --- cardiovascular disease --- nanomedicine --- liposome --- nanoformulation --- RNA-dependent RNA polymerase --- remdesivir --- chloroquine --- SARS-CoV-2 --- COVID-19 --- spike glycoproteins --- Acorus calamus --- ethnomedicinal --- phytochemistry --- toxicity --- pharmacological action --- clinical trial --- neuroprotective --- neurological --- metabolic application --- kurarinone --- coronavirus --- HCoV-OC43 --- autophagy --- infection --- MRC-5 cell --- LC3 --- p62/SQSTM1 protein --- n/a

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The present book, a reprint of the Molecules Special Issue "Insecticide, Acaricide, Repellent and Antimicrobial Development", presents key advances in the development of effective and eco-friendly insecticides, acaricides, repellents, and antimicrobials, including products of natural origin.

Medicine --- Lauraceae --- Aedes aegypti --- Aedes albopictus --- Culex quinquefasciatus --- antibacterial --- antifungal --- antioxidants --- compatibility --- date palm dust mites --- host defense --- Oligonychus afrasiaticus --- Metarhizium anisopliae --- natural acaricide --- synergism --- 1-Chlorooctadecane --- Lamiaceae --- Clinopodium nepeta subsp. nepeta --- Clinopodium nepeta subsp. glandulosum --- essential oils --- chemical variability --- biological activities --- Citrullus colocynthis --- spinasterol, 22,23-dihydrospinasterol --- fernenol --- insecticidal activity --- LC50 --- electrical penetration graph --- peach potato aphid --- antifeedants --- attractants --- structure-activity relationships --- fractionation --- reducing activity --- biomolecules --- antibiofilm --- microbial infection --- mangrove --- larvicidal activity --- enzyme inhibition --- Rhizophora mucronata --- repellent --- mosquitoes --- Erigeron --- Conyza bonariensis --- Conyza canadensis --- Conyza sumatrensis --- mosquito --- vector control --- naphthoquinones --- plumbagin --- Spodoptera littoralis --- insect growth inhibition --- carnivorous plants --- Nepenthes --- botanical-based insecticide --- cereals --- green grain protectant --- essential oil nanoformulation --- stored-product beetles --- Tenebrionidae --- Chagas' disease transmission --- triatomines --- peridomiciliary use --- Argentina --- biopesticides --- bio-based pesticides --- chemical ecology --- pest control --- natural products --- storage --- monoterpenes --- bioinsecticide --- insect pest --- toxicity --- eugenol derivatives --- amino alcohols --- semisynthetic insecticides --- bioinsecticides --- phenylpropanoids --- Spodoptera frugiperda --- urban pests --- agricultural pests --- aphids --- cockroaches --- kissing bugs --- insect vectors --- green insecticides --- moth pests --- non-target toxicity --- stored product pests --- termites --- Lauraceae --- Aedes aegypti --- Aedes albopictus --- Culex quinquefasciatus --- antibacterial --- antifungal --- antioxidants --- compatibility --- date palm dust mites --- host defense --- Oligonychus afrasiaticus --- Metarhizium anisopliae --- natural acaricide --- synergism --- 1-Chlorooctadecane --- Lamiaceae --- Clinopodium nepeta subsp. nepeta --- Clinopodium nepeta subsp. glandulosum --- essential oils --- chemical variability --- biological activities --- Citrullus colocynthis --- spinasterol, 22,23-dihydrospinasterol --- fernenol --- insecticidal activity --- LC50 --- electrical penetration graph --- peach potato aphid --- antifeedants --- attractants --- structure-activity relationships --- fractionation --- reducing activity --- biomolecules --- antibiofilm --- microbial infection --- mangrove --- larvicidal activity --- enzyme inhibition --- Rhizophora mucronata --- repellent --- mosquitoes --- Erigeron --- Conyza bonariensis --- Conyza canadensis --- Conyza sumatrensis --- mosquito --- vector control --- naphthoquinones --- plumbagin --- Spodoptera littoralis --- insect growth inhibition --- carnivorous plants --- Nepenthes --- botanical-based insecticide --- cereals --- green grain protectant --- essential oil nanoformulation --- stored-product beetles --- Tenebrionidae --- Chagas' disease transmission --- triatomines --- peridomiciliary use --- Argentina --- biopesticides --- bio-based pesticides --- chemical ecology --- pest control --- natural products --- storage --- monoterpenes --- bioinsecticide --- insect pest --- toxicity --- eugenol derivatives --- amino alcohols --- semisynthetic insecticides --- bioinsecticides --- phenylpropanoids --- Spodoptera frugiperda --- urban pests --- agricultural pests --- aphids --- cockroaches --- kissing bugs --- insect vectors --- green insecticides --- moth pests --- non-target toxicity --- stored product pests --- termites

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The present book, a reprint of the Molecules Special Issue "Insecticide, Acaricide, Repellent and Antimicrobial Development", presents key advances in the development of effective and eco-friendly insecticides, acaricides, repellents, and antimicrobials, including products of natural origin.

Lauraceae --- Aedes aegypti --- Aedes albopictus --- Culex quinquefasciatus --- antibacterial --- antifungal --- antioxidants --- compatibility --- date palm dust mites --- host defense --- Oligonychus afrasiaticus --- Metarhizium anisopliae --- natural acaricide --- synergism --- 1-Chlorooctadecane --- Lamiaceae --- Clinopodium nepeta subsp. nepeta --- Clinopodium nepeta subsp. glandulosum --- essential oils --- chemical variability --- biological activities --- Citrullus colocynthis --- spinasterol, 22,23-dihydrospinasterol --- fernenol --- insecticidal activity --- LC50 --- electrical penetration graph --- peach potato aphid --- antifeedants --- attractants --- structure-activity relationships --- fractionation --- reducing activity --- biomolecules --- antibiofilm --- microbial infection --- mangrove --- larvicidal activity --- enzyme inhibition --- Rhizophora mucronata --- repellent --- mosquitoes --- Erigeron --- Conyza bonariensis --- Conyza canadensis --- Conyza sumatrensis --- mosquito --- vector control --- naphthoquinones --- plumbagin --- Spodoptera littoralis --- insect growth inhibition --- carnivorous plants --- Nepenthes --- botanical-based insecticide --- cereals --- green grain protectant --- essential oil nanoformulation --- stored-product beetles --- Tenebrionidae --- Chagas’ disease transmission --- triatomines --- peridomiciliary use --- Argentina --- biopesticides --- bio-based pesticides --- chemical ecology --- pest control --- natural products --- storage --- monoterpenes --- bioinsecticide --- insect pest --- toxicity --- eugenol derivatives --- amino alcohols --- semisynthetic insecticides --- bioinsecticides --- phenylpropanoids --- Spodoptera frugiperda --- urban pests --- agricultural pests --- aphids --- cockroaches --- kissing bugs --- insect vectors --- green insecticides --- moth pests --- non-target toxicity --- stored product pests --- termites --- n/a --- Chagas' disease transmission