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There are various malignant tumors in the head and neck area, including oral cavity, pharynx, sinonasal cavity, and salivary glands. Squamous cell carcinoma is the most common cancer among head and neck cancers. In salivary glands, there are many types of malignancies that can develop, such as malignant lymphoma, adenoid cystic carcinoma, adenocarcinoma, and mesenchymal tumors. In a clinical setting, imaging, such as computed tomography (CT) and magnetic resonance imaging (MRI), is very important in terms of the prediction of the histological type and the evaluation of the extent of invasion of adjacent structures. In basic research, there are few animal models in head and neck malignancies. In this Special Issue, we broadly discuss the basic and clinical research in head and neck malignancies.

Medicine --- BDNF --- Brain-Derived Neurotrophic Factor --- navigation --- spatial processing --- trauma --- trauma processing --- Post-Traumatic Stress Disorder --- PSTD --- allocentric --- hippocampus --- sinonasal tract --- malignant tumor --- CT --- MRI --- neuropsychiatric presentation of encephalitis --- paraneoplastic encephalitis --- autoimmune encephalitis --- infectious encephalitis --- diffuse large B-cell lymphoma --- canaloplasty --- non-perforating surgical procedures --- corticosteroid-induced glaucoma --- Schlemm’s canal --- neck mass --- diffusion-weighted MRI --- apparent diffusion coefficient --- procalcitonin --- bacterial meningitis --- viral meningitis --- antibiotic therapy --- biomarker --- differential diagnosis --- human papillomavirus --- human cancer --- head and neck --- reduction therapy --- head and neck squamous cell carcinoma (HNSCC) --- neutrophil-to-lymphocyte ratio (NLR) --- myeloid-derived suppressor cells (MDSC) --- aldehyde dehydrogenase 1 (ALDH1) --- prognosis --- prodigiosin --- doxorubicin --- priming --- influx --- autophagy --- cervical --- cellulitis --- abscess --- deep neck infection --- diabetes mellitus --- MAP1LC3B --- SQSTM1 --- subsites --- tumorigenesis --- oral cancer --- Nox4 --- oral tongue cancer --- squamous cell carcinoma --- surgery --- head and neck squamous cell carcinoma --- HPV --- 11q13 --- gene amplification --- immunohistochemistry --- head and neck cancer --- radiotherapy --- neutrophil/lymphocyte ratio --- survival --- ZFAND4 --- ANUBL1 --- oral squamous cell carcinoma --- nucleotide excision repair --- genetic polymorphism --- concurrent chemoradiotherapy --- HNSCC --- MIF --- 4-IPP --- metabolism --- annexin A9 --- annexin A10 --- differentiation grade --- NGS --- BDNF --- Brain-Derived Neurotrophic Factor --- navigation --- spatial processing --- trauma --- trauma processing --- Post-Traumatic Stress Disorder --- PSTD --- allocentric --- hippocampus --- sinonasal tract --- malignant tumor --- CT --- MRI --- neuropsychiatric presentation of encephalitis --- paraneoplastic encephalitis --- autoimmune encephalitis --- infectious encephalitis --- diffuse large B-cell lymphoma --- canaloplasty --- non-perforating surgical procedures --- corticosteroid-induced glaucoma --- Schlemm’s canal --- neck mass --- diffusion-weighted MRI --- apparent diffusion coefficient --- procalcitonin --- bacterial meningitis --- viral meningitis --- antibiotic therapy --- biomarker --- differential diagnosis --- human papillomavirus --- human cancer --- head and neck --- reduction therapy --- head and neck squamous cell carcinoma (HNSCC) --- neutrophil-to-lymphocyte ratio (NLR) --- myeloid-derived suppressor cells (MDSC) --- aldehyde dehydrogenase 1 (ALDH1) --- prognosis --- prodigiosin --- doxorubicin --- priming --- influx --- autophagy --- cervical --- cellulitis --- abscess --- deep neck infection --- diabetes mellitus --- MAP1LC3B --- SQSTM1 --- subsites --- tumorigenesis --- oral cancer --- Nox4 --- oral tongue cancer --- squamous cell carcinoma --- surgery --- head and neck squamous cell carcinoma --- HPV --- 11q13 --- gene amplification --- immunohistochemistry --- head and neck cancer --- radiotherapy --- neutrophil/lymphocyte ratio --- survival --- ZFAND4 --- ANUBL1 --- oral squamous cell carcinoma --- nucleotide excision repair --- genetic polymorphism --- concurrent chemoradiotherapy --- HNSCC --- MIF --- 4-IPP --- metabolism --- annexin A9 --- annexin A10 --- differentiation grade --- NGS