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This book provides a comprehensive overview of skeletal muscle structure, function, and regulation at the cellular and molecular levels. In addition, the book covers various topics, such as muscle contraction, energy metabolism, fatigue, adaptation, and plasticity. This book discusses skeletal muscle anatomy and histology and then covers muscle contraction's molecular and cellular mechanisms. Also, it includes an in-depth discussion of the sarcomere, the basic unit of muscle contraction, and the role of calcium in the process of muscle contraction. This book also explores the energy metabolism of skeletal muscle, including the role of ATP, glycogen, and fatty acids in providing energy for muscle contraction. Additionally, the book covers the mechanisms of fatigue, including peripheral and central factors contributing to muscle fatigue. Other topics covered include muscle adaptation to exercise, the molecular and cellular mechanisms of muscle hypertrophy and atrophy, and the influence of age, sex, and disease on skeletal muscle function. Overall, Skeletal Muscle Physiology: An Update to Anatomy and Function thoroughly explores the structure and function of skeletal muscle, making it an essential resource for students and professionals in exercise science, sports medicine, and physiology. The auto-summaries have been generated by a recursive clustering algorithm via the Dimensions Auto-summarizer by Digital Science handled by Subject Matter Experts and the external editor. The editor of this book selected which SN content should be auto-summarized and decided its order of appearance. Please be aware that the auto-summaries consist of original sentences, but are not representative of its original paper, since we do not show the full length of the publication. Please note that only published SN content is represented here, and that machine-generated books are still at an experimental stage.
Musculoskeletal system. --- Motor ability. --- Bones. --- Physiology. --- Muscles --- Anatomy. --- Bone Physiology. --- Muscle Physiology.
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Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of Springer Nature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the 21st volume of a continuing series.
Cytology. --- Stem cells. --- Inflammation. --- Cancer. --- Sports medicine. --- Muscles --- Cell Biology. --- Stem Cell Biology. --- Cancer Biology. --- Sports Medicine. --- Muscle Physiology. --- Physiology.
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This valuable resource provides a systematic account of the biochemistry of smooth muscle contraction. As a comprehensive guide to this rapidly growing area of research, it covers the structure and characteristic properties of contractile and regulatory proteins, with special emphasis on their predicted function in the live muscle. Also included in this book are intermediate filament proteins, and desmin and vimentin, whose function in smooth muscle is unknown; and several enzymes involved in the phosphorylation-dephosphorylation of contractile and other proteins.
Human physiology --- Smooth muscle --- Muscle contraction. --- Physiology. --- Physiology --- Contraction of muscles --- Muscles --- Contractility (Biology) --- Nonstriated muscle --- Unstriated muscle --- Contraction --- Motility --- Smooth muscle - Physiology
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This is the first book to combine under one cover classic studies and recent discoveries in muscle physiology. The author examines the structure of muscle and nerve and shows how structure is intimately related to function. He also discusses the cellular processes that take place when muscles work and how certain clinical disorders result from specific defects in muscle and nerve. This book collects all of the availabe knowledge on skeletal muscle anatomy and physiology into a logically organized, easy-to-follow reference
Muscle, Skeletal --- Mechanoreceptors --- Neuromuscular Junction --- Striated muscle --- Muscle strié --- physiology --- Physiology --- Physiologie --- Mechanoreceptors. --- Physiology. --- physiology. --- 612 --- -981460.jpg --- Spieren: anatomie --- Spieren: fysiologie --- Striped muscle --- Muscles --- Fysiologie --- Muscle strié --- 981460.jpg --- Striated muscle - Physiology. --- Muscle, Skeletal - physiology. --- Neuromuscular Junction - physiology.
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Malnutrition is becoming a more prominent health problem, with an increasing number of elderly CKD patients being put on dialysis. In addition, the presence of inflammation, sarcopenia/frailty, diabetes, and CVD is a definite and independent risk factor associated with higher mortality in this population. Although the restriction of protein intake has been recommended to protect eGFR decline, hyperphosphatemia, and hyperkalemia in CKD patients, it might accelerate the loss of skeletal muscle and adipose mass, leading to a poor prognosis. Therefore, flexible responses are considered regarding whether protein restriction should be continued or loosened in pre-dialysis CKD patients. In undernourished elderly patients undergoing hemodialysis, sufficient calorie/protein intake is necessary to counteract the development of sarcopenia/frailty. It is expected that the application of new drugs including phosphate binders and potassium chelators may achieve both a high enough intake and balanced levels of phosphate and potassium. Furthermore, the improvement of deficient micronutrients and poor appetite is also necessary. Comprehensive care is essential for the wellbeing of elderly patients undergoing hemodialysis. The topicof this Special Issue is “Extension of Healthy Life Span of Dialysis Patients in the Era of a 100-Year Life”.
hypertension --- body weight --- mortality --- sodium --- dialysis --- malnutrition --- protein energy wasting (PEW) --- sarcopenia --- carnitine --- carnitine deficiency --- end-stage kidney disease --- peritoneal dialysis --- hemodialysis --- frailty --- protein energy wasting --- hypercatabolism --- renal rehabilitation --- exercise --- sarcopenia and frailty --- nutritional support --- protein synthesis --- muscle physiology --- physical activity --- exercise tolerance --- quality of life --- skeletal muscle --- aging --- chronic kidney disease --- diabetes --- CKD-MBD --- FGF23 --- aKlotho --- phosphate-binder --- zinc --- cardiovascular disease --- potassium --- potassium excretion --- blood pressure --- salt --- CKD --- fat mass --- visceral fat --- subcutaneous fat --- nutrition --- body mass index --- obesity paradox --- magnetic resonance imaging --- diffusion tensor imaging --- arterial spin labeling --- blood oxygenation level-dependent --- nutritional status --- dialysis patients --- clinical malnutrition --- older individuals --- n/a
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Malnutrition is becoming a more prominent health problem, with an increasing number of elderly CKD patients being put on dialysis. In addition, the presence of inflammation, sarcopenia/frailty, diabetes, and CVD is a definite and independent risk factor associated with higher mortality in this population. Although the restriction of protein intake has been recommended to protect eGFR decline, hyperphosphatemia, and hyperkalemia in CKD patients, it might accelerate the loss of skeletal muscle and adipose mass, leading to a poor prognosis. Therefore, flexible responses are considered regarding whether protein restriction should be continued or loosened in pre-dialysis CKD patients. In undernourished elderly patients undergoing hemodialysis, sufficient calorie/protein intake is necessary to counteract the development of sarcopenia/frailty. It is expected that the application of new drugs including phosphate binders and potassium chelators may achieve both a high enough intake and balanced levels of phosphate and potassium. Furthermore, the improvement of deficient micronutrients and poor appetite is also necessary. Comprehensive care is essential for the wellbeing of elderly patients undergoing hemodialysis. The topicof this Special Issue is “Extension of Healthy Life Span of Dialysis Patients in the Era of a 100-Year Life”.
Medicine --- hypertension --- body weight --- mortality --- sodium --- dialysis --- malnutrition --- protein energy wasting (PEW) --- sarcopenia --- carnitine --- carnitine deficiency --- end-stage kidney disease --- peritoneal dialysis --- hemodialysis --- frailty --- protein energy wasting --- hypercatabolism --- renal rehabilitation --- exercise --- sarcopenia and frailty --- nutritional support --- protein synthesis --- muscle physiology --- physical activity --- exercise tolerance --- quality of life --- skeletal muscle --- aging --- chronic kidney disease --- diabetes --- CKD-MBD --- FGF23 --- aKlotho --- phosphate-binder --- zinc --- cardiovascular disease --- potassium --- potassium excretion --- blood pressure --- salt --- CKD --- fat mass --- visceral fat --- subcutaneous fat --- nutrition --- body mass index --- obesity paradox --- magnetic resonance imaging --- diffusion tensor imaging --- arterial spin labeling --- blood oxygenation level-dependent --- nutritional status --- dialysis patients --- clinical malnutrition --- older individuals --- hypertension --- body weight --- mortality --- sodium --- dialysis --- malnutrition --- protein energy wasting (PEW) --- sarcopenia --- carnitine --- carnitine deficiency --- end-stage kidney disease --- peritoneal dialysis --- hemodialysis --- frailty --- protein energy wasting --- hypercatabolism --- renal rehabilitation --- exercise --- sarcopenia and frailty --- nutritional support --- protein synthesis --- muscle physiology --- physical activity --- exercise tolerance --- quality of life --- skeletal muscle --- aging --- chronic kidney disease --- diabetes --- CKD-MBD --- FGF23 --- aKlotho --- phosphate-binder --- zinc --- cardiovascular disease --- potassium --- potassium excretion --- blood pressure --- salt --- CKD --- fat mass --- visceral fat --- subcutaneous fat --- nutrition --- body mass index --- obesity paradox --- magnetic resonance imaging --- diffusion tensor imaging --- arterial spin labeling --- blood oxygenation level-dependent --- nutritional status --- dialysis patients --- clinical malnutrition --- older individuals
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