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Our understanding of the pathology of amyotrophic lateral sclerosis is a continuously changing field. New hypotheses are generated with each new discovery; they are abandoned to be reanalyzed after some time under the light of new observations. This book present a series of reviews from experts in different aspects of the disease focus on these hypotheses. There are also a few review chapters providing clear examples of these new observations that make the field to reanalyze previous conclusions.
Amyotrophic lateral sclerosis. --- ALS (Disease) --- Gehrig's disease --- Lateral sclerosis --- Lou Gehrig's disease --- Motor neurone disease --- Sclerosis, Amyotrophic lateral --- Motor neurons --- Neuromuscular diseases --- Diseases --- Neurology & clinical neurophysiology
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Amyotrophic lateral sclerosis --- Pathophysiology. --- ALS (Disease) --- Gehrig's disease --- Lateral sclerosis --- Lou Gehrig's disease --- Motor neurone disease --- Sclerosis, Amyotrophic lateral --- Motor neurons --- Neuromuscular diseases --- Diseases
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Motor Neurone Disease is one of the most difficult conditions to manage medically and socially. A disease which leads to the loss of control of most muscle systems of the body, it has no known cause and no cure. For this reason, clinicians have traditionally been reluctant to reveal the diagnosis to sufferers or their families and the condition has become known as one of the best kept secrets of medical practice. However in recent years a number of organizations have set up to support sufferers and their families and consequently, the public profile of the condition has changed dramatically.
Amyotrophic lateral sclerosis.
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ALS (Disease)
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Gehrig's disease
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Lateral sclerosis
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Lou Gehrig's disease
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Motor neurone disease
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Sclerosis, Amyotrophic lateral
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Motor neurons
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Neuromuscular diseases
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Diseases
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ALS, also known as Lou Gehrig''s disease, cannot be cured but it can be treated. A great deal can be done to treat the symptoms of ALS, to improve an individuals quality of life, and to help families, caregivers, and loved ones to cope with the disease. This extensively revised and rewritten new edition of the bestselling Amyotrophic Lateral Sclerosis: A Guide For Patients and Families addresses all of those needs, and brings up-to-date important information to those living with the reality of ALS.The book is completely revised throughout and contains NEW information on: * Recently developed a
Amyotrophic lateral sclerosis. --- Motor neurons --- ALS (Disease) --- Gehrig's disease --- Lateral sclerosis --- Lou Gehrig's disease --- Motor neurone disease --- Sclerosis, Amyotrophic lateral --- Neuromuscular diseases --- Diseases. --- Diseases
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Amyotrophic lateral sclerosis. --- Motor neurons --- ALS (Disease) --- Gehrig's disease --- Lateral sclerosis --- Lou Gehrig's disease --- Motor neurone disease --- Sclerosis, Amyotrophic lateral --- Neuromuscular diseases --- Diseases. --- Diseases
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A diagnosis of amyotrophic lateral sclerosis (also known as Lou Gehrig's disease or motor neuron disease) is a progressive neurodegenerative disorder that exerts a notorious life-shortening physical toll. Understandably, clinicians are keen to avoid a wrong diagnosis when there are such serious consequences, but any delay in diagnosis can result in unnecessary, and sometimes harmful, interventions, and prevents prompt implementation of much-needed physical and emotional support. Starting from the premise that ALS is not one disease but a syndrome, with a spectrum of upper and lower motor neuron involvement, this highly readable resource examines the causes of diagnostic delay and how to avoid them. With no diagnostic test to confirm the disease, no mandatory investigations and very few plausible 'ALS mimics', the authors take a pragmatic approach to what must always be a clinical diagnosis. With case presentations and teaching points to aid understanding, 'Fast Facts: ALS' will give clinicians the confidence to confirm or exclude a diagnosis of ALS, so that individuals facing this most challenging of conditions can receive rapid multidisciplinary support to maximize the quality of their remaining life. Contents: • Defining the syndrome • Epidemiology and pathophysiology • The first symptoms • Differential diagnosis • Investigations • Emerging diagnostic biomarkers
Amyotrophic lateral sclerosis --- Diagnosis. --- ALS (Disease) --- Gehrig's disease --- Lateral sclerosis --- Lou Gehrig's disease --- Motor neurone disease --- Sclerosis, Amyotrophic lateral --- Motor neurons --- Neuromuscular diseases --- Diseases
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This book contains selected peer-reviewed chapters which cover updated information on ALS written by international researchers. Update on Amyotrophic Lateral Sclerosis is comprised of 13 chapters from some of the world's top central nervous system researchers and neurologists to provide a timely review of the most recent developments in ALS, covering historic aspects, experimental animal models, genetics, pathogenesis, clinical aspects and imagenology among others. Contributors from Belgium, France, Japan, India, Italy, Mexico, Russia, South Africa, and Switzerland have collaborated enthusiastically and efficiently, dedicating their time to create this reader-friendly yet comprehensive work which includes many explanatory figures, tables and photos to enhance legibility and make the book clinically useful. We are looking forward with confidence and pride in the remarkable role that this book will play for a new vision and mission.
Amyotrophic lateral sclerosis. --- ALS (Disease) --- Gehrig's disease --- Lateral sclerosis --- Lou Gehrig's disease --- Motor neurone disease --- Sclerosis, Amyotrophic lateral --- Motor neurons --- Neuromuscular diseases --- Diseases --- Medicine --- Neurology --- Mental and Behavioural Disorders and Diseases of the Nervous System --- Health Sciences
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Amyotrophic lateral sclerosis. --- Amyotrophic lateral sclerosis --- Treatment. --- ALS (Disease) --- Gehrig's disease --- Lateral sclerosis --- Lou Gehrig's disease --- Motor neurone disease --- Sclerosis, Amyotrophic lateral --- Motor neurons --- Neuromuscular diseases --- Diseases
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Though considerable amount of research, both pre-clinical and clinical, has been conducted during recent years, Amyotrophic Lateral Sclerosis (ALS) remains one of the mysterious diseases of the 21st century. Great efforts have been made to develop pathophysiological models and to clarify the underlying pathology, and with novel instruments in genetics and transgenic techniques, the aim for finding a durable cure comes into scope. On the other hand, most pharmacological trials failed to show a benefit for ALS patients. In this book, the reader will find a compilation of state-of-the-art reviews about the etiology, epidemiology, and pathophysiology of ALS, the molecular basis of disease progression and clinical manifestations, the genetics familial ALS, as well as novel diagnostic criteria in the field of electrophysiology. An overview over all relevant pharmacological trials in ALS patients is also included, while the book concludes with a discussion on current advances and future trends in ALS research.
Amyotrophic lateral sclerosis. --- ALS (Disease) --- Gehrig's disease --- Lateral sclerosis --- Lou Gehrig's disease --- Motor neurone disease --- Sclerosis, Amyotrophic lateral --- Motor neurons --- Neuromuscular diseases --- Diseases --- Life Sciences --- Neuroscience --- Electrophysiology --- Neurophysiology
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'Motor Neuron Disease' aims to give patients and their families a greater understanding of the condition and a sense of hope and enablement in the face of what can be a quite frightening diagnosis.
Amyotrophic lateral sclerosis. --- Motor neurons --- ALS (Disease) --- Gehrig's disease --- Lateral sclerosis --- Lou Gehrig's disease --- Motor neurone disease --- Sclerosis, Amyotrophic lateral --- Neuromuscular diseases --- Diseases. --- Diseases --- Amyotrophic lateral sclerosis
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