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Secondary metabolism in model systems
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ISBN: 9780080445014 0080445012 9780080474335 0080474330 1280968001 9781280968006 9786610968008 Year: 2004 Publisher: Amsterdam Boston Elsevier

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The chapters presented in Secondary Metabolism in Model Systems are a microcosm of what the recent completion, or near completion, of various genome projects are enabling biochemists to understand not only about control and regulation of secondary metabolism, and how various pathways relate to each other, but also about its relation to primary metabolism. A major paradigm shift is occurring in the way researchers need to view ""secondary"" metabolism in the future.It is also clear that model systems, such as the ones discussed in the symposium, are providing new information and insight almost

Secondary metabolism in model systems
Authors: ---
ISBN: 9780080445014 0080445012 9780080474335 0080474330 1280968001 9781280968006 9786610968008 Year: 2004 Publisher: Amsterdam ; London : Elsevier,

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Abstract

The chapters presented in Secondary Metabolism in Model Systems are a microcosm of what the recent completion, or near completion, of various genome projects are enabling biochemists to understand not only about control and regulation of secondary metabolism, and how various pathways relate to each other, but also about its relation to primary metabolism. A major paradigm shift is occurring in the way researchers need to view ""secondary"" metabolism in the future.It is also clear that model systems, such as the ones discussed in the symposium, are providing new information and insight almost


Book
A Broader View for Plant EvoDevo: Novel Approaches for Diverse Model Systems
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Year: 2017 Publisher: Frontiers Media SA

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This collection attempts to integrate work pertaining to a fundamental question in plant evolution: What are the molecular underpinnings for the origin of different plant forms? Among the many facets this question touches are the transition to land, the emergence of vascular plants, the origin of the seed and the origin and diversification of floral form. We aim to bring to the forefront the most salient and original plant systems and approaches within an inclusive phylogenetic context that encompasses representatives of the major lineages of land plants.


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A Broader View for Plant EvoDevo: Novel Approaches for Diverse Model Systems
Authors: --- ---
Year: 2017 Publisher: Frontiers Media SA

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Abstract

This collection attempts to integrate work pertaining to a fundamental question in plant evolution: What are the molecular underpinnings for the origin of different plant forms? Among the many facets this question touches are the transition to land, the emergence of vascular plants, the origin of the seed and the origin and diversification of floral form. We aim to bring to the forefront the most salient and original plant systems and approaches within an inclusive phylogenetic context that encompasses representatives of the major lineages of land plants.


Book
A Broader View for Plant EvoDevo: Novel Approaches for Diverse Model Systems
Authors: --- ---
Year: 2017 Publisher: Frontiers Media SA

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Abstract

This collection attempts to integrate work pertaining to a fundamental question in plant evolution: What are the molecular underpinnings for the origin of different plant forms? Among the many facets this question touches are the transition to land, the emergence of vascular plants, the origin of the seed and the origin and diversification of floral form. We aim to bring to the forefront the most salient and original plant systems and approaches within an inclusive phylogenetic context that encompasses representatives of the major lineages of land plants.


Book
Antisense RNA Design, Delivery, and Analysis
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ISBN: 107162010X 1071620096 Year: 2022 Publisher: New York Springer Nature

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This open access volume gathers a variety of models, delivery systems, and approaches that can be used to assess RNA technology for exploiting antisense as a therapeutic intervention. Beginning with a section on the design of antisense technology and their delivery, the book continues by covering model systems developed to evaluate efficacy, both in vivo and in vitro, as well as methods to evaluate preclinically the toxicity associated with these new potential drugs, and intellectual property considerations. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Antisense RNA Design, Delivery, and Analysis provides basic knowledge and a large collection of methods to facilitate the work of newcomers to this vibrant and expanding field. This book was conceived thanks to the network DARTER (Delivery of Antisense RNA Therapeutics). DARTER is funded by the EU Cooperation of Science and Technology (COST), which aims to enhance interaction and collaborations between researchers in Europe and other countries.


Book
Model systems in biology : history, philosophy, and practical concerns
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ISBN: 0262370026 0262046946 0262370034 Year: 2022 Publisher: Cambridge, Massachusetts : The MIT Press,

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"Instead of arguing for a specific animal model, Striedter will review the history and philosophy of animal models in biomedical research, examining their various advantages and limitations"--


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Salmonella : Pathogenesis and Host Restriction
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Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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This Special Issue “Applications of Stable Isotopes and Tritium in Hydrology” addresses the current state-of-the-art applications of stable isotopes and tritium in studies of hydrological process and the whole water cycle. The six scientific papers belonging to this SI show a wide variety of isotope applications in various studies performed locally or regionally, but the conclusions obtained may be valid worldwide. Precipitation, groundwater, and surface waters belong to classical water bodies, while evapotranspiration, effects of farming, and drip water in karst caves seldom present applications of water isotopes.

Keywords

Research & information: general --- Salmonella --- biofilm --- innate immunity --- extracellular polymeric substances --- S. Typhi --- S. Typhimurium --- S. diarizonae --- PagN --- adhesin --- invasin --- alleles --- allelic variants --- organoids --- enteroids --- host-pathogen interactions --- model systems --- infectious diseases --- organotypic culture system --- genomic island --- SPI-1 --- pathogenicity island --- comparative genomics --- type III secretion system --- host adaptation --- convergent evolution --- genome degradation --- genomic lesions --- Salmonella Typhi --- two-component system --- cpxR --- CsgD --- curli --- cellulose --- CpxR --- plasmid --- Salmonella enterica --- antimicrobial resistance --- long-read sequencing --- hybrid assembly --- iron homeostasis and regulation --- chicken --- pathogenicity --- iron transport --- Salmonella --- biofilm --- innate immunity --- extracellular polymeric substances --- S. Typhi --- S. Typhimurium --- S. diarizonae --- PagN --- adhesin --- invasin --- alleles --- allelic variants --- organoids --- enteroids --- host-pathogen interactions --- model systems --- infectious diseases --- organotypic culture system --- genomic island --- SPI-1 --- pathogenicity island --- comparative genomics --- type III secretion system --- host adaptation --- convergent evolution --- genome degradation --- genomic lesions --- Salmonella Typhi --- two-component system --- cpxR --- CsgD --- curli --- cellulose --- CpxR --- plasmid --- Salmonella enterica --- antimicrobial resistance --- long-read sequencing --- hybrid assembly --- iron homeostasis and regulation --- chicken --- pathogenicity --- iron transport


Book
Genetic Determinants of Human Longevity
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ISBN: 3039216791 3039216783 Year: 2019 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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In the last two decades, due to the continuous increase of lifespans in Westernsocieties, and the consequent growing of the elderly population, have witnessedan increase in the number of studies on biological and molecular factors able topromote healthy aging and reach longevity. The study of the genetic componentof human longevity demonstrated that it accounts for 25% of intra populationphenotype variance. The efforts made to characterize the genetic determinantssuggested that the maintenance of cellular integrity, inflammation, oxidativestress response, DNA repair, as well as the use of nutrients, represent the mostimportant pathways correlated with a longer lifespan. However, although aplethora of variants were indicated to be associated with human longevity, onlyvery few were successfully replicated in different populations, probably becauseof population specificity, missing heritability as well as a complex interactionamong genetic factors with lifestyle and cultural factors, which modulate theindividual chance of living longer. Thus, many challenges remain to be addressedin the search for the genetic components of human longevity. This Special Issue isaimed to unify the progress in the analysis of the genetic determinants of humanlongevity, to take stock of the situation and point to future directions of the field.We invite submissions for reviews, research articles, short-communicationsdealing with genetic association studies in human longevity, including all types ofgenetic variation, as well as the characterization of longevity-related genes.


Book
Salmonella : Pathogenesis and Host Restriction
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

This Special Issue “Applications of Stable Isotopes and Tritium in Hydrology” addresses the current state-of-the-art applications of stable isotopes and tritium in studies of hydrological process and the whole water cycle. The six scientific papers belonging to this SI show a wide variety of isotope applications in various studies performed locally or regionally, but the conclusions obtained may be valid worldwide. Precipitation, groundwater, and surface waters belong to classical water bodies, while evapotranspiration, effects of farming, and drip water in karst caves seldom present applications of water isotopes.

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