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The biology of cytoplasmic microtubules
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ISBN: 089072007X 9780890720073 Year: 1975 Publisher: New York (N.Y.): New York Academy of Sciences,

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Microtubules


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Biological functions of microtubules and related structures
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Year: 1982 Publisher: New York (N.Y.): Academic press

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Microtubules

Microtubules
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ISBN: 0471561932 9780471561934 Year: 1994 Publisher: New York: Wiley,

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Reflecting significant advances in microtubule research during the past decade, a prominent group of contributors present reviews dealing with three central topics--the biochemistry and assembly of tubulin dimer; associated proteins and regulation of microtubule function; and microtubule organization and function in the cell.


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Tubulin-Binding Agents
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ISSN: 03401022 ISBN: 9783540690368 9783540690399 3540690360 Year: 2009 Volume: 286 Publisher: Berlin, Heidelberg Springer-Verlag Berlin Heidelberg

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reviews. The SAR data are discussed in light of the structural information available for each agent. The second chapter focuses on the total synthesis of the marine sponge-derived polyketide discodermolide. A comprehensive survey of the synthetic chemistry efforts of several groups over a 14-year period is provided together with a compa- son of the different approaches. The third chapter describes a comprehensive study of the mechanisms of activity of microtubules stabilizing drugs. Thermodynamic, kinetic, structural and fu- tional data on microtubules stabilizing drugs are discussed in an interdisciplinary manner to generate a time-resolved  picture of the interaction of the drugs with different tubulin forms. The fourth and fifth chapters review the efforts and achievements made in the characterization of the structure of the complexes of tubulin with microtubules stabilizing agents by NMR (Chapter 4) and EM (Chapter 5). Especially evident is the discrepancy of the results obtained for epothilones, where the two techniques deliver radically different structures of the bound drug. Both NMR and EM models are, however, able to explain a consistent set of SAR data. The authors of the two chapters discuss critically the advantages and limitations of each methodology.


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The kinesin superfamily handbook : transporter, creator, destroyer
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ISBN: 0429958242 0429958250 0429491557 113858956X Year: 2020 Publisher: Boca Raton : CRC Press,

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"This book brings together current information on the families that make up the kinesin superfamily of molecular motors in one comprehensive text; an ideal reference for researchers looking to make comparisons between different families, for specific information on a family, or simply for an overview of the kinesin superfamily. Information is clearly structured and grouped according to individual families and organized in a standardized way, allowing the reader to search and retrieve information on this large superfamily of molecular motors and understand how its individual members carry out a diverse variety of cellular functions. Features: The first book dedicated to the entire kinesin superfamily Enables a fuller understanding of this family of proteins which is becoming an increasing focus of research due to its involvement in diseases such as cancer, neuropathies and ciliopathies. Written in a manner accessible to a range of researchers in the life and medical sciences, including biophysicists, biochemists, and medical researchers"--

Plant microtubules : potential for biotechnology
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ISBN: 3540671056 Year: 2000 Publisher: Heidelberg : Springer,

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Untangling the Role of Tau in Physiology and Pathology
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Year: 2020 Publisher: Frontiers Media SA

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact


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Untangling the Role of Tau in Physiology and Pathology
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Year: 2020 Publisher: Frontiers Media SA

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact


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Microtubules
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ISBN: 354013283X 3642696546 364269652X Year: 1984 Publisher: Berlin Springer

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Dyneins. : structure, biology and disease
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ISBN: 0128097027 0128094710 9780128097021 9780128094716 Year: 2018 Publisher: London, England : Academic Press,

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