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Blood Circulation. --- Microcirculation --- Microcirculation
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This dissertation by Alexandra Högstedt explores the microvascular effects of insulin in the skin, focusing on the interplay between glucose metabolism and microvascular function. The research aims to develop an in vivo model to study metabolic and microvascular responses to insulin, utilizing microdialysis techniques for local drug delivery and monitoring. The study investigates the impact of insulin on skin blood flow and metabolism, highlighting the role of the nitric oxide pathway and interactions with other physiological systems such as the renin-angiotensin system. It provides insight into microvascular dysfunction related to insulin resistance and proposes future applications for assessing insulin effects in various patient groups.
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This dissertation by Fredrik Iredahl investigates the microvascular and metabolic responses in the skin, with a focus on developing minimally invasive in vivo models. It explores the skin's role as a model for systemic conditions such as hypertension and diabetes mellitus, emphasizing the importance of understanding microvascular function. The research compares various optical measurement techniques and investigates the effects of insulin on skin vasodilation, mediated by nitric oxide. The studies highlight the significance of measurement techniques and drug delivery protocols in assessing skin responses, contributing to advancements in understanding cardiovascular and diabetic conditions. The intended audience includes medical researchers and professionals in clinical and experimental medicine.
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Microcirculation --- Microcirculation --- Vasoconstriction --- Vasodilation --- Congresses
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Microcirculation --- Blood --- Microcirculation. --- Communication. --- Circulation
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