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The analysis of circulating tumor cells (CTCs) as a real-time liquid biopsy approach can be used to obtain new insights into metastasis biology, and as companion diagnostics to improve the stratification of therapies and to obtain insights into the therapy-induced selection of cancer cells. In this book, we will cover all the different facets of CTCs to assemble a huge corpus of knowledge on cancer dissemination: technologies for their enrichment, detection, and characterization; their analysis at the single-cell level; their journey as CTC microemboli; their clinical relevance; their biology with the epithelial-to-mesenchymal transition (EMT); their stem-cell properties; their potential to initiate metastasis at distant sites; their ex vivo expansion; and their escape from the immune system.
n/a --- FOLFIRINOX --- immunofluorescence imaging --- AR-V7 --- circulating tumour cells --- chemoradioresistance --- CTC-based treatment decisions --- rVAR2 --- immunophenotyping --- immune system --- CellSearch® --- flow cytometry --- clinical trials --- circulating tumor DNA --- synaptophysin --- stem cells --- colorectal cancer --- melanoma --- CTC biology --- platelets --- AR --- CTC capture technology --- castration resistant prostate cancer (CRPC) --- PD-L1 expression --- rovalpituzumab tesirine --- HMB-45 --- thymidylate synthase --- ctDNA --- tumor cell dissemination --- solid cancers --- metastasis --- locally advanced rectal cancer --- miRNA --- epithelial-to-mesenchymal transition (EMT) --- NSCLC --- tumor biomarkers --- tumor stem cells --- circulating tumor cells --- major histocompatibility complex class I (MHCI) --- bone marrow --- heterogeneity --- cerebrospinal liquid biopsy --- fish --- glioma --- in vivo flow cytometry --- colorectal surgery --- CellSearch --- single-cell analysis --- disseminated tumor cells --- EasyCount slides --- microsatellite instability --- circulating plasma cells --- circulating leukemia cells --- ARV7 --- SLUG --- androgen receptor --- metastatic colorectal cancer --- leukocyte-derived extracellular vesicles --- prostate cancer (PCa) --- neutrophils --- liquid biopsy --- enzalutamide --- CD133 --- enrichment and detection technologies --- biomarkers --- immune checkpoint inhibitors --- biomarker --- RAD23B --- microbiome --- integrin B1 --- ACCEPT --- emboli --- small-cell lung carcinoma --- EPISPOT --- microfluidics --- early breast cancer --- circulating tumor cells (CTC) --- tumor-initiating cells (TICs) --- immunomodulation --- xenograft models --- CTC-derived xenografts --- malaria --- circulating tumor cells (CTCs) --- clinical utility --- exosomes --- liquid surgery --- ctRNA --- CTCs --- epithelial–mesenchymal transition --- targeted therapy --- hematological cells --- gene expression analysis --- hepatocellular carcinoma (HCC) --- breast cancer --- EpCAM enrichment --- prostate cancer --- CTC --- abiraterone --- fibronectin --- CTC-derived ex vivo models --- CTMat --- chromogranin A --- CTM --- exosome --- epithelial-mesenchymal transition
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When the domestic government, the private sector, and people in various professional fields talk about long-term care issues, they all focus on creating a warm and home-like care institution. However, we actively emphasize the importance of community-based long-term care. For “aging in place”, the development of domestic non-institutional care is still in its infancy, and some long-term care needs must still be met through institutional care, and the facilitation of the extension or outreach of community-based care and respite service platforms for the development of community-based long-term care still rely on institutional care. The history of the development of long-term care in Taiwan is much shorter than that of Japan, Europe, the United States, and Canada. Despite years of hard work and rapid development, the long-term care resources needed to establish a complete system in terms of universalization, fairness, accessibility, and selectivity are not available. In the future, based on the soundness of institutional care, it hoped that outreach will move toward the goals of community care and aging in place. We hope the studies in this Special Issue will help further develop clinical medicine for healthcare and stainability.
Medicine --- sarcopenia --- bioimpedance analysis --- computed tomography --- discordance --- effect --- protection --- catheter --- hemodialysis --- meta-analysis --- trial sequential analysis --- Long-term oxygen therapy --- home mechanical ventilation --- patient-reported experience measures --- quality of care --- healthcare --- sustainability --- hepatocellular carcinoma --- health-related quality of life --- minimal clinically important difference --- survival --- serum urate --- menopause --- hypertension --- xanthine dehydrogenase --- cross-sectional cohort study --- diabetic foot ulcer --- peripheral arterial disease --- incidence --- prevalence --- cost --- National Health Insurance Service data --- erythrodermic psoriasis --- secukinumab --- addiction --- smoking --- alcohol --- cannabis --- virtual reality --- musculoskeletal disorders --- randomized controlled tria --- ceftaroline --- ceftriaxone --- community-acquired pneumonia --- safety --- eravacycline --- complicated intra-abdominal infection --- efficacy --- mortality --- laparoscopic --- open surgery --- non-metastatic colorectal cancer --- surgical complication --- oncologic outcome --- single surgeon experience --- doripenem --- acute bacterial infection --- pneumonia --- intra-abdominal infection --- complicated urinary tract infection --- ultrasound-guided injection --- laser assisted --- long-axis injection --- chronic disease --- multimorbidity --- suicidal thoughts --- suicidal plans --- stroke --- post-acute care --- medical referral system --- propensity score matching --- resistance training --- arterial pressure --- disease prevention --- caffeine --- older adults --- frailty --- medication --- primary care --- white matter hyperintensity --- MRI --- healthcare quotient --- chronic --- older adults living in super-aging society --- mild cognitive impairment --- walking speed --- depression --- urinary tract infection --- rapid culture --- antibiotic susceptibility testing (AST), evidence-based prescription --- antibiotics --- antimicrobial resistance (AMR), rapid diagnostics --- prediction --- deep learning --- conventional neural network --- bariatric surgery --- hospital emergency department --- queuing theory --- decision support --- cost optimization --- health behavior --- socioeconomic status --- Korea --- cardiovascular disease --- postprandial --- hypotension --- blood pressure --- elderly --- lung cancer --- physical activity --- season --- preoperative --- wearable --- macrosomia --- large for gestational age --- machine learning --- ensemble methods --- sensitivity --- specificity --- clinical deterioration --- early medical intervention --- electronic health records --- hospital rapid response team --- intensive care units --- medical records system --- computerized --- osteoporosis screening --- artificial intelligence --- convolutional neural networks --- dental panoramic radiographs --- palliative care --- nursing homes --- symptom assessment --- drug therapy --- therapeutics --- longitudinal studies --- occupational medicine --- forensic medicine --- insurance medicine --- psychoactive substances --- clinical --- forensic --- law --- ethics --- uric acid --- risk factor --- epidemiology --- cardiometabolic diseases --- healthcare and sustainability --- therapy of internal medicine diseases
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When the domestic government, the private sector, and people in various professional fields talk about long-term care issues, they all focus on creating a warm and home-like care institution. However, we actively emphasize the importance of community-based long-term care. For “aging in place”, the development of domestic non-institutional care is still in its infancy, and some long-term care needs must still be met through institutional care, and the facilitation of the extension or outreach of community-based care and respite service platforms for the development of community-based long-term care still rely on institutional care. The history of the development of long-term care in Taiwan is much shorter than that of Japan, Europe, the United States, and Canada. Despite years of hard work and rapid development, the long-term care resources needed to establish a complete system in terms of universalization, fairness, accessibility, and selectivity are not available. In the future, based on the soundness of institutional care, it hoped that outreach will move toward the goals of community care and aging in place. We hope the studies in this Special Issue will help further develop clinical medicine for healthcare and stainability.
sarcopenia --- bioimpedance analysis --- computed tomography --- discordance --- effect --- protection --- catheter --- hemodialysis --- meta-analysis --- trial sequential analysis --- Long-term oxygen therapy --- home mechanical ventilation --- patient-reported experience measures --- quality of care --- healthcare --- sustainability --- hepatocellular carcinoma --- health-related quality of life --- minimal clinically important difference --- survival --- serum urate --- menopause --- hypertension --- xanthine dehydrogenase --- cross-sectional cohort study --- diabetic foot ulcer --- peripheral arterial disease --- incidence --- prevalence --- cost --- National Health Insurance Service data --- erythrodermic psoriasis --- secukinumab --- addiction --- smoking --- alcohol --- cannabis --- virtual reality --- musculoskeletal disorders --- randomized controlled tria --- ceftaroline --- ceftriaxone --- community-acquired pneumonia --- safety --- eravacycline --- complicated intra-abdominal infection --- efficacy --- mortality --- laparoscopic --- open surgery --- non-metastatic colorectal cancer --- surgical complication --- oncologic outcome --- single surgeon experience --- doripenem --- acute bacterial infection --- pneumonia --- intra-abdominal infection --- complicated urinary tract infection --- ultrasound-guided injection --- laser assisted --- long-axis injection --- chronic disease --- multimorbidity --- suicidal thoughts --- suicidal plans --- stroke --- post-acute care --- medical referral system --- propensity score matching --- resistance training --- arterial pressure --- disease prevention --- caffeine --- older adults --- frailty --- medication --- primary care --- white matter hyperintensity --- MRI --- healthcare quotient --- chronic --- older adults living in super-aging society --- mild cognitive impairment --- walking speed --- depression --- urinary tract infection --- rapid culture --- antibiotic susceptibility testing (AST), evidence-based prescription --- antibiotics --- antimicrobial resistance (AMR), rapid diagnostics --- prediction --- deep learning --- conventional neural network --- bariatric surgery --- hospital emergency department --- queuing theory --- decision support --- cost optimization --- health behavior --- socioeconomic status --- Korea --- cardiovascular disease --- postprandial --- hypotension --- blood pressure --- elderly --- lung cancer --- physical activity --- season --- preoperative --- wearable --- macrosomia --- large for gestational age --- machine learning --- ensemble methods --- sensitivity --- specificity --- clinical deterioration --- early medical intervention --- electronic health records --- hospital rapid response team --- intensive care units --- medical records system --- computerized --- osteoporosis screening --- artificial intelligence --- convolutional neural networks --- dental panoramic radiographs --- palliative care --- nursing homes --- symptom assessment --- drug therapy --- therapeutics --- longitudinal studies --- occupational medicine --- forensic medicine --- insurance medicine --- psychoactive substances --- clinical --- forensic --- law --- ethics --- uric acid --- risk factor --- epidemiology --- cardiometabolic diseases --- healthcare and sustainability --- therapy of internal medicine diseases
Choose an application
When the domestic government, the private sector, and people in various professional fields talk about long-term care issues, they all focus on creating a warm and home-like care institution. However, we actively emphasize the importance of community-based long-term care. For “aging in place”, the development of domestic non-institutional care is still in its infancy, and some long-term care needs must still be met through institutional care, and the facilitation of the extension or outreach of community-based care and respite service platforms for the development of community-based long-term care still rely on institutional care. The history of the development of long-term care in Taiwan is much shorter than that of Japan, Europe, the United States, and Canada. Despite years of hard work and rapid development, the long-term care resources needed to establish a complete system in terms of universalization, fairness, accessibility, and selectivity are not available. In the future, based on the soundness of institutional care, it hoped that outreach will move toward the goals of community care and aging in place. We hope the studies in this Special Issue will help further develop clinical medicine for healthcare and stainability.
Medicine --- sarcopenia --- bioimpedance analysis --- computed tomography --- discordance --- effect --- protection --- catheter --- hemodialysis --- meta-analysis --- trial sequential analysis --- Long-term oxygen therapy --- home mechanical ventilation --- patient-reported experience measures --- quality of care --- healthcare --- sustainability --- hepatocellular carcinoma --- health-related quality of life --- minimal clinically important difference --- survival --- serum urate --- menopause --- hypertension --- xanthine dehydrogenase --- cross-sectional cohort study --- diabetic foot ulcer --- peripheral arterial disease --- incidence --- prevalence --- cost --- National Health Insurance Service data --- erythrodermic psoriasis --- secukinumab --- addiction --- smoking --- alcohol --- cannabis --- virtual reality --- musculoskeletal disorders --- randomized controlled tria --- ceftaroline --- ceftriaxone --- community-acquired pneumonia --- safety --- eravacycline --- complicated intra-abdominal infection --- efficacy --- mortality --- laparoscopic --- open surgery --- non-metastatic colorectal cancer --- surgical complication --- oncologic outcome --- single surgeon experience --- doripenem --- acute bacterial infection --- pneumonia --- intra-abdominal infection --- complicated urinary tract infection --- ultrasound-guided injection --- laser assisted --- long-axis injection --- chronic disease --- multimorbidity --- suicidal thoughts --- suicidal plans --- stroke --- post-acute care --- medical referral system --- propensity score matching --- resistance training --- arterial pressure --- disease prevention --- caffeine --- older adults --- frailty --- medication --- primary care --- white matter hyperintensity --- MRI --- healthcare quotient --- chronic --- older adults living in super-aging society --- mild cognitive impairment --- walking speed --- depression --- urinary tract infection --- rapid culture --- antibiotic susceptibility testing (AST), evidence-based prescription --- antibiotics --- antimicrobial resistance (AMR), rapid diagnostics --- prediction --- deep learning --- conventional neural network --- bariatric surgery --- hospital emergency department --- queuing theory --- decision support --- cost optimization --- health behavior --- socioeconomic status --- Korea --- cardiovascular disease --- postprandial --- hypotension --- blood pressure --- elderly --- lung cancer --- physical activity --- season --- preoperative --- wearable --- macrosomia --- large for gestational age --- machine learning --- ensemble methods --- sensitivity --- specificity --- clinical deterioration --- early medical intervention --- electronic health records --- hospital rapid response team --- intensive care units --- medical records system --- computerized --- osteoporosis screening --- artificial intelligence --- convolutional neural networks --- dental panoramic radiographs --- palliative care --- nursing homes --- symptom assessment --- drug therapy --- therapeutics --- longitudinal studies --- occupational medicine --- forensic medicine --- insurance medicine --- psychoactive substances --- clinical --- forensic --- law --- ethics --- uric acid --- risk factor --- epidemiology --- cardiometabolic diseases --- healthcare and sustainability --- therapy of internal medicine diseases
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