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Book
Advances in Diagnosis and Therapy of Neuroendocrine Neoplasms
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Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

This Special Issue is dedicated to neuroendocrine neoplasms (NENs), a category of malignancy that demonstrates wide clinical heterogeneity, posing major challenges in diagnosis and management. There have been significant advances in the field of NEN genomics, pathology, imaging, and treatment over the past five years. NENs are examples of rare tumours (although their incidence and prevalence are increasing) where international collaborative efforts have allowed the generation of high-level evidence to guide optimal patient-centred care. This issue presents both reviews and original papers to provide comprehensive state-of-the-art understanding of this fascinating disease.

Keywords

Medicine --- small bowel neuroendocrine tumours --- pancreatic neuroendocrine tumours --- liver metastases --- midgut --- meta-analysis --- neuroendocrine tumors --- carcinoid heart disease --- carcinoid syndrome --- somatostatin analogues --- metastases --- multidisciplinary --- management --- outcome --- grading --- staging --- neuroendocrine neoplasms --- chemotherapy --- temozolomide --- metronomic treatment --- second-line --- NOTCH --- cancer-driven genes --- mutational mechanism --- germline mutations --- small cell lung carcinoma --- pancreatic NET --- small bowel NET --- medullary thyroid carcinoma --- malignant castration-resistant prostatic cells --- quality performance indicators --- QPIs --- cancer care --- neuroendocrine tumour --- NETs --- modified Delphi --- CommNETs --- pancreatic neuroendocrine neoplasms --- neuroendocrine tumor --- long-term functional outcomes --- pancreatectomy --- diabetes mellitus --- pancreatic exocrine insufficiency --- body mass index --- parenchyma-sparing surgery --- neuroendocrine tumours --- curative surgery --- resection --- follow-up --- guidelines --- relapse --- recurrence --- risk factor --- mixed non-neuroendocrine neuroendocrine neoplasms --- MiNENs --- mixed adeno-neuroendocrine carcinoma --- MANEC --- 2017 WHO classification --- 2019 WHO classification --- small bowel neuroendocrine tumours --- pancreatic neuroendocrine tumours --- liver metastases --- midgut --- meta-analysis --- neuroendocrine tumors --- carcinoid heart disease --- carcinoid syndrome --- somatostatin analogues --- metastases --- multidisciplinary --- management --- outcome --- grading --- staging --- neuroendocrine neoplasms --- chemotherapy --- temozolomide --- metronomic treatment --- second-line --- NOTCH --- cancer-driven genes --- mutational mechanism --- germline mutations --- small cell lung carcinoma --- pancreatic NET --- small bowel NET --- medullary thyroid carcinoma --- malignant castration-resistant prostatic cells --- quality performance indicators --- QPIs --- cancer care --- neuroendocrine tumour --- NETs --- modified Delphi --- CommNETs --- pancreatic neuroendocrine neoplasms --- neuroendocrine tumor --- long-term functional outcomes --- pancreatectomy --- diabetes mellitus --- pancreatic exocrine insufficiency --- body mass index --- parenchyma-sparing surgery --- neuroendocrine tumours --- curative surgery --- resection --- follow-up --- guidelines --- relapse --- recurrence --- risk factor --- mixed non-neuroendocrine neuroendocrine neoplasms --- MiNENs --- mixed adeno-neuroendocrine carcinoma --- MANEC --- 2017 WHO classification --- 2019 WHO classification


Book
Psychosocial Considerations for Children and Adolescents Living with Rare Diseases
Authors: ---
ISBN: 3036550909 3036550895 Year: 2022 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

This Special Issue of the journal Children constitutes an opportune moment to reflect on the psychosocial needs of children living with rare diseases and of their families. As medical advances, treatments, and developments have enabled many of these children to survive infancy and to live into adulthood, progress brings with it concerns and opportunities to enhance the psychosocial quality of life of children living with rare diseases, and of their families. This Special Issue reflects the current state of psychosocial research, which is primarily qualitative in nature. There are no scientifically rigorous randomized clinical trials to create an evidence base of effective psychosocial interventions for the provision of care to children with rare diseases and to their families; nevertheless, the papers within this Special Issue provide a reflection on the state of the science, including ideas about future research and practice. In this next section we share observations about the contributions made by each of the 13 articles, which cover a diverse range of topics.

Keywords

Psychology --- cancer --- childhood cancer --- adaptation --- psychological --- neoplasm --- oncology --- sibling --- social support --- social adjustment --- palliative care --- end-of-life care --- equity --- public health approach --- compassionate communities --- caregiving --- parents --- psychosocial support --- rare disease --- advance care planning --- decision-making --- family caregiver --- psychosocial care --- communication --- pediatric --- adolescents and young adults --- healthcare needs --- chronic illness --- AYA transition --- Beckwith–Wiedemann syndrome --- emotional-behavioral problems --- psychosocial difficulties --- psychomotor development --- preschool-age children --- pediatric chronic illness --- rare diseases --- family caregivers --- gender differences --- genetic or rare diseases --- health outcomes --- illness perception --- parenting stress --- siblings --- bereavement --- emotions --- psychosocial distress --- pediatrics --- complex chronic conditions --- pediatric to adult transition --- special needs --- interventions --- care coordination --- transition readiness --- family burden --- parental need --- urea cycle disorders --- E-IMD --- inherited metabolic diseases --- medullary thyroid carcinoma --- psychosocial --- young adults --- life-limiting conditions --- adolescents --- age-appropriate --- development --- cognitive functions --- children --- families --- medical complexity --- policy --- advocacy --- n/a --- Beckwith-Wiedemann syndrome


Book
Advances in Diagnosis and Therapy of Neuroendocrine Neoplasms
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

This Special Issue is dedicated to neuroendocrine neoplasms (NENs), a category of malignancy that demonstrates wide clinical heterogeneity, posing major challenges in diagnosis and management. There have been significant advances in the field of NEN genomics, pathology, imaging, and treatment over the past five years. NENs are examples of rare tumours (although their incidence and prevalence are increasing) where international collaborative efforts have allowed the generation of high-level evidence to guide optimal patient-centred care. This issue presents both reviews and original papers to provide comprehensive state-of-the-art understanding of this fascinating disease.


Book
Advances in the Diagnosis and Treatment of Thyroid Carcinoma
Authors: ---
ISBN: 3036553339 3036553347 Year: 2022 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

This reprint is related to the latest research in the field of thyroid surgery, including molecular and imaging diagnosis, surgical treatment, and the treatment of recurrent disease and advanced thyroid carcinoma.

Keywords

Medicine --- Oncology --- thyroid carcinoma --- prophylactic central lymph node dissection --- lymph node metastases --- RET --- medullary thyroid carcinoma --- clinical management --- variants of uncertain significance --- differentiated thyroid cancer --- papillary thyroid cancer --- minimal extrathyroidal extension --- radioactive iodine therapy --- prognosis --- TNM --- histology --- multifocality --- lymph node metastasis --- vascular invasion --- autoimmune thyroid diseases --- radioiodine refractory --- Lenvatinib --- 18F-FDG-PET/CT --- cost-benefit analysis --- economics --- medical --- thyroid neoplasms --- radiomics --- ultrasound --- magnetic resonance imaging --- computer tomography --- prediction --- classification --- angiogenic microenvironment --- prognostic factors --- antiangiogenic therapy --- therapeutic target --- tumor microenvironment --- tumor behavior --- proliferation pathways --- cell cycle control pathways --- angiogenesis process --- thyroid cancer --- Gal-3 expression --- NIFTP --- EFVPTC --- lymphocytic thyroiditis (LT) --- immunohistochemical (IHC) analysis --- molecular imaging --- theranostics --- companion diagnostics --- immunoPET --- anaplastic thyroid cancer --- poorly thyroid cancer --- genetic landscape --- genetically guided therapy --- fluorodeoxyglucose F18 (18F-FDG) --- positron emission tomography (PET) --- magnetic resonance imaging (MRI) --- recurrence --- neoplasm metastasis --- thyroid surgery --- hypoparathyroidism --- fluorescence-guided surgery --- near-infrared autofluorescence --- PRKAR1A --- PKA --- Carney complex --- cAMP --- bone metastasis --- metastasectomy --- stereotactic radiosurgery --- ultrasound imaging --- thyroid nodule --- fine-needle aspiration --- papillary thyroid carcinoma --- lobectomy --- operative extent --- CONUT score --- tyrosine kinase inhibitors

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