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Mast [Family]

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Mast, Louis.

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This dissertation by Anders Carlsson explores the role of mast cells and probiotics in regulating intestinal barrier function. The research investigates how stress and inflammation affect the permeability of the intestinal mucosa, which is crucial in preventing harmful substances from entering the body. The study employs in vitro and ex vivo experiments on animal and human tissues to understand the mechanisms involved. The findings indicate that stress impacts the epithelial barrier via vasoactive intestinal polypeptide and mast cells. Probiotics are shown to protect against barrier dysfunction, suggesting a potential therapeutic role in conditions like Crohn's disease and ulcerative colitis. The work aims to enhance understanding of the intestinal barrier's regulation under stress and the beneficial effects of probiotics.

Intestinal mucosa. --- Mast cells.

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Mast, van der, Jan

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Histamine --- Mast cells