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This book offers a comprehensive exploration of geochemical kinetics--the application of chemical kinetics to geological problems, both theoretical and practical. Geochemical Kinetics balances the basic theories of chemical kinetics with a thorough examination of advanced theories developed by geochemists, such as nonisothermal kinetics and inverse theories, including geochronology (isotopic dating), thermochronology (temperature-time history), and geospeedometry (cooling rates). The first chapter provides an introduction and overview of the whole field at an elementary level, and the subsequent chapters develop theories and applications for homogeneous reactions, mass and heat transfer, heterogeneous reactions, and inverse problems. Most of the book's examples are from high-temperature geochemistry, with a few from astronomy and environmental sciences. Appendixes, homework problems for each major section, and a lengthy reference list are also provided. Readers should have knowledge of basic differential equations, some linear algebra, and thermodynamics at the level of an undergraduate physical chemistry course. Geochemical Kinetics is a valuable resource for anyone interested in the mathematical treatment of geochemical questions.

Chemical kinetics --- Geochemistry --- Absorptivities. --- Activated complex. --- Activation energy. --- Advection. --- Arrhenius plot. --- Asymptotic cooling. --- Avogadro constant. --- Avrami equation. --- Backward reaction. --- Batch melting. --- Binary diffusivity. --- Boltzmann distribution. --- Catalyst. --- Chapman mechanism. --- Chemical reactions. --- Collision theory. --- Component exchange. --- Concordia. --- Conservation equations. --- Convective crystal growth. --- Cooling history. --- Darken equation. --- Decay chains. --- Decay reactions. --- Diffusion and flow. --- Diffusion distance. --- Diffusion. --- Diffusivity. --- Dodson’s equations. --- Eddy diffusion. --- Energy conservation. --- Equilibrium. --- Extinct nuclides. --- Falling sphere. --- Fick’s law. --- First-order precision. --- Ganguly’s method. --- Geochemical kinetics. --- Geochronology. --- Geospeedometry. --- Heat conduction. --- Heterogeneous reactions. --- Infrared spectroscopy. --- Integrated error function. --- Interstitial sites. --- Inverse problems. --- Isochrons. --- Jumping frequency. --- Kohlrausch’s law. --- Law of mass action. --- Many-body problems. --- Mass conservation. --- Nanoparticle aggregation.

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There is talk of an upcoming antibiotic armageddon, with untreatable post-operative infections, and similarly untreatable complications after chemotherapy. Indeed, the now famous “O’Neill Report” (https://amr-review.org/) suggests that, by 2050, more people might die from antibiotic-resistant bacterial infections than from cancer. While we are still learning all the subtle drivers of antibiotic resistance, it seems increasingly clear that we need to take a “one health” approach, curtailing the use of antibiotics in both human and veterinary medicine. However, there are no new classes of antibiotics on our horizon. Maybe something that has been around “forever” can come to our rescue—bacteriophages! Nevertheless, it is also necessary to do things differently, and use these new antimicrobials appropriately. Therefore, an in-depth study of bacteriophage biology and case-by-case applications might be required. Whilst by no means comprehensive, this book does cover some of the many topics related to bacteriophages as antimicrobials, including their use in human therapy and aquaculture. It also explores the potential use of phage endolysins as substitutes of antibiotics in two sectors where there is an urgent need—human therapy and the agro-food industry. Last but not least, there is an excellent perspective article on phage therapy implementation.

Medicine --- bacteriophages --- dairy industry --- pathogens --- lactic acid bacteria --- fermentation failure --- biofilms --- antimicrobial resistance --- antimicrobials --- lysins --- horizontal gene transfer, transduction --- biofilm --- phage therapy --- resistance --- bacteriophage --- models --- agent based --- mass action --- bacterial phage resistance --- regression modeling --- MRSA --- Clostridium difficile --- Clostridium difficile infection --- microbiome --- in vitro fermentation model --- marine vibrios --- biological control --- aquaculture --- interactions --- vibriosis --- Aeromonas hydrophila --- Motile Aeromonas Septicemia --- MAS --- multiple-antibiotic-resistance --- striped catfish (Pangasianodon hypophthalmus) --- endolysin --- antibiotics --- one health --- protein engineering --- Aeromonas salmonicida --- furunculosis --- phage-resistant mutants --- proteins --- infrared spectroscopy --- lysin --- lytic enzyme --- peptidoglycan hydrolase --- antimicrobial --- antibacterial --- antibiotic resistance --- bacteriophage therapy --- Nagoya Protocol --- CRISPR CAS --- phage isolation --- phage resistance --- Staphylococcus --- Kayvirus --- Vibrio anguillarum --- fish larvae --- challenge trials --- phage display --- enzybiotics --- Bacteriophages --- diabetic foot ulcer --- osteomyelitis --- Staphylococcus aureus --- Antibiotic-resistant bacteria --- lysogenic conversion --- prophage induction --- read recruitment --- shiga toxin --- American Foulbrood --- phage --- Paenibacillus larvae --- Brevibacillus laterosporus --- treatment --- safety --- bystander phage therapy --- Mycobacterium smegmatis --- mycobacteriophages --- directed evolution --- PlyC CHAP --- protein net charge --- CBD-independent --- FoldX --- STEC-specific bacteriophage --- whole genome sequencing --- STEC O145 strains --- antimicrobial agent --- Pseudomonas aeruginosa --- dual-species --- antibiotic --- synergy --- simultaneous --- sequential --- microbiome therapy --- evolution --- bacteriophages --- dairy industry --- pathogens --- lactic acid bacteria --- fermentation failure --- biofilms --- antimicrobial resistance --- antimicrobials --- lysins --- horizontal gene transfer, transduction --- biofilm --- phage therapy --- resistance --- bacteriophage --- models --- agent based --- mass action --- bacterial phage resistance --- regression modeling --- MRSA --- Clostridium difficile --- Clostridium difficile infection --- microbiome --- in vitro fermentation model --- marine vibrios --- biological control --- aquaculture --- interactions --- vibriosis --- Aeromonas hydrophila --- Motile Aeromonas Septicemia --- MAS --- multiple-antibiotic-resistance --- striped catfish (Pangasianodon hypophthalmus) --- endolysin --- antibiotics --- one health --- protein engineering --- Aeromonas salmonicida --- furunculosis --- phage-resistant mutants --- proteins --- infrared spectroscopy --- lysin --- lytic enzyme --- peptidoglycan hydrolase --- antimicrobial --- antibacterial --- antibiotic resistance --- bacteriophage therapy --- Nagoya Protocol --- CRISPR CAS --- phage isolation --- phage resistance --- Staphylococcus --- Kayvirus --- Vibrio anguillarum --- fish larvae --- challenge trials --- phage display --- enzybiotics --- Bacteriophages --- diabetic foot ulcer --- osteomyelitis --- Staphylococcus aureus --- Antibiotic-resistant bacteria --- lysogenic conversion --- prophage induction --- read recruitment --- shiga toxin --- American Foulbrood --- phage --- Paenibacillus larvae --- Brevibacillus laterosporus --- treatment --- safety --- bystander phage therapy --- Mycobacterium smegmatis --- mycobacteriophages --- directed evolution --- PlyC CHAP --- protein net charge --- CBD-independent --- FoldX --- STEC-specific bacteriophage --- whole genome sequencing --- STEC O145 strains --- antimicrobial agent --- Pseudomonas aeruginosa --- dual-species --- antibiotic --- synergy --- simultaneous --- sequential --- microbiome therapy --- evolution