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The very first international working discussion on slow infections of the nervous system was entitled "Slow, Latent, and Temperate Virus Infec tions" and was held at the National Institutes of Health (NIH) in December 1964. The primary impetus was the discovery and investigation of kuru in New Guinea by D. Carleton Gajdusek, M. D. This working discussion brought together investigators in human and veterinary medicine, virolo gists, microbiologists, and neuropathologists actively engaged in laboratory work with viruses that illustrated properties of latency, masking, slowness, or temperateness, with emphasis on subacute and chronic neurologic dis eases of unknown etiology. In the Preface to the monograph of published papers presented at the working discussion, Gajdusek and Gibbs wrote the following: After microbiology had given solution to the etiology of most acute infections of the central nervous system and after fungi and bacteria had been incriminated in impor tant chronic disorders of the nervous system such as torula and tuberculosis men ingitis, we have been left, in neurology, with a wide range of subacute and chronic affections of the central nervous systems of unknown etiology. Some of these diseases, still listed as idiopathic, are among the most prevalent afflictions of the central nervous system. Many others with familial patterns of occurrence do not yet have their basic pathogenesis or underlying metabolic defect elucidated, although we tend to think of them as genetically mediated.
Bovine spongiform encephalopathy --- Social aspects. --- BSE (Disease) --- Mad cow disease --- Spongiform encephalopathy, Bovine --- Cattle --- Prion diseases in animals --- Creutzfeldt-Jakob disease --- Virus diseases
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Bovine spongiform encephalopathy -- United States -- Prevention. --- Cattle -- Virus diseases -- United States -- Prevention. --- Bovine spongiform encephalopathy --- Veterinary Medicine --- Health & Biological Sciences --- BSE (Disease) --- Mad cow disease --- Spongiform encephalopathy, Bovine --- Cattle --- Prion diseases in animals --- Creutzfeldt-Jakob disease --- Prevention --- Virus diseases --- Prevention.
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Bovine spongiform encephalopathy --- 591.481.1 --- 619 --- 636.2 --- BSE (Disease) --- Mad cow disease --- Spongiform encephalopathy, Bovine --- Cattle --- Prion diseases in animals --- Creutzfeldt-Jakob disease --- 636.2 Large ruminants. Cattle, oxen --- Large ruminants. Cattle, oxen --- 591.481.1 Brain of vertebrates. Encephalon. Cerebellum --- Brain of vertebrates. Encephalon. Cerebellum --- Virus diseases
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Fear of mad cow disease, a lethal illness transmitted from infected beef to humans, has spread from Europe to the United States and around the world. Originally published to much acclaim in France, this scientific thriller, available in English for the first time and updated with a new chapter on developments in 2001, tells of the hunt for the cause of an enigmatic class of fatal brain infections, of which mad cow disease is the latest incarnation. In gripping, nontechnical prose, Maxime Schwartz details the deadly manifestations of these diseases throughout history, describes the major players and events that led to discoveries about their true nature, and outlines our current state of knowledge. The book concludes by addressing the question we all want answered: should we be afraid? The story begins in the eighteenth century with the identification of a mysterious illness called scrapie that was killing British sheep. It was not until the 1960's that scientists understood that several animal and human diseases, including scrapie, were identical, and together identified them as transmissible spongiform encephalopathy (TSE). The various guises assumed throughout history by TSE include an illness called kuru in a cannibalistic tribe in Papua New Guinea, an infectious disease that killed a group of children who had been treated for growth hormone deficiencies, and mad cow disease. Revealing the fascinating process of scientific discovery that led to our knowledge of TSE, Schwartz relates pivotal events in the history of biology, including the Pasteurian revolution, the birth of genetics, the emergence of molecular biology, and the latest developments in biotechnology. He also explains the Nobel Prize-winning prion hypothesis, which has rewritten the rules of biological heredity and is a key link between the distinctive diseases of TSE. Up-to-date, informative, and thoroughly captivating, How the Cows Turned Mad tells the story of a disease that continues to elude on many levels. Yet science has come far in understanding its origins, incubation, and transmission. This authoritative book is a stunning case history that illuminates the remarkable progression of science.
Bovine spongiform encephalopathy. --- Prion diseases in animals --- History. --- agriculture. --- beef. --- biology. --- brain infection. --- cannibalism. --- carnism. --- carnivore. --- cattle. --- cows. --- disease. --- food and culture. --- food studies. --- food. --- genetics. --- health. --- heredity. --- infectious disease. --- kuru. --- life sciences. --- mad cow. --- mammals. --- meat eating. --- meat. --- medical nonfiction. --- medical science. --- medicine. --- molecular biology. --- neuroscience. --- nonfiction. --- papua new guinea. --- pasteur. --- prion disease. --- prion hypothesis. --- science. --- scrapie. --- sheep. --- transmissible spongiform encephalopathy. --- tse. --- zoology.
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An investigation of science, politics and our food production system, this text exposes the bogus science, political interference and flawed policies that threaten our food supply. The author tells the story of BSE, revealing how top scientists have been muzzled and how the epidemic continues. Then, against a backdrop of burning cows, Andrew Rowell exposes how trade and macro-economic policies overruled good science in the foot and mouth catastrophe. He also opens the black box of the so-called GM revolution to expose the myth behind the marketing. In tracing how critics are silenced in the bo
Genetically modified foods --- Bovine spongiform encephalopathy --- Foot-and-mouth disease --- Aftosa fever --- Aphtha, Epizootic --- Aphtha, Malignant --- Aphthous fever --- Eczema epizootica --- Epizootic aphtha --- Hoof-and-mouth disease --- Malignant aphtha --- Picornavirus infections --- Veterinary virology --- BSE (Disease) --- Mad cow disease --- Spongiform encephalopathy, Bovine --- Cattle --- Prion diseases in animals --- Creutzfeldt-Jakob disease --- GM foods --- Genetically engineered foods --- Food --- Virus diseases --- Biotechnology --- Professional ethics. Deontology --- Molecular biology --- Infectious diseases. Communicable diseases --- Veterinary pathology --- Environmental protection. Environmental technology
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Cattle Diseases --- Prion Diseases --- Public Health --- Environment and Public Health --- Central Nervous System Infections --- Animal Diseases --- Neurodegenerative Diseases --- Disease Outbreaks --- Encephalopathy, Bovine Spongiform --- Health Care --- Diseases --- Central Nervous System Diseases --- Nervous System Diseases --- Zoology and Animal Sciences. Veterinary Science --- Veterinary Epidemiology --- Veterinary Epidemiology. --- Bovine spongiform encephalopathy --- Food chains (Ecology) --- Creutzfeldt-Jakob disease --- CJD (Disease) --- Creutzfeldt-Jakob syndrome --- Heidenhain syndrome --- Jakob-Creutzfeldt disease --- Jakob-Creutzfeldt syndrome --- Jakob's disease --- Spastic pseudosclerosis --- Sub-acute spongiform encephalopathy --- Subacute spongiform encephalopathy --- Central nervous system --- Presenile dementia --- Prion diseases --- Food webs (Ecology) --- Animals --- Biological productivity --- Ecology --- Niche (Ecology) --- Nutrient cycles --- BSE (Disease) --- Mad cow disease --- Spongiform encephalopathy, Bovine --- Cattle --- Prion diseases in animals --- Food --- Virus diseases --- Trophic ecology
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In 1986, the emergence of a novel brain disease in British cattle presented a unique challenge to scientists. How that challenge was addressed has been the subject of a public inquiry and numerous academic studies conducted to date. However, none of these investigations has sought to examine the reasoning of scientists during this critical period in the public health of the UK. Using concepts and techniques in informal logic, argumentation and fallacy theory, this study reconstructs and evaluates the reasoning of scientists in the ten-year period between 1986 and 1996. Specifically, a form of presumptive reasoning is described in which extensive use is made of arguments traditionally identified as informal fallacies. In the context of the adverse epistemic conditions that confronted scientists during the BSE epidemic, these arguments were anything but fallacious, serving instead to confer a number of epistemic gains upon scientific inquiry. This book argues for a closer integration of philosophy with public health science, an integration that is exemplified by the case of scientific reasoning during the BSE affair. It will therefore be of interest to advanced students, academics, researchers and professionals in the areas of public health science and epidemiology, as well as philosophical disciplines such as informal logic, argumentation and fallacy theory and epistemology.
Bovine spongiform encephalopathy. --- Mad cow disease. --- Prion diseases. --- Bovine spongiform encephalopathy --- Reasoning --- Fallacies (Logic) --- Logic --- Science --- Prion Diseases --- Philosophy --- Europe --- Cattle Diseases --- Dementia --- Public Health --- Natural Science Disciplines --- Neurodegenerative Diseases --- Delirium, Dementia, Amnestic, Cognitive Disorders --- Medicine --- Central Nervous System Infections --- Geographic Locations --- Animal Diseases --- Brain Diseases --- Disciplines and Occupations --- Humanities --- Creutzfeldt-Jakob Syndrome --- Encephalopathy, Bovine Spongiform --- Epidemiology --- Great Britain --- Health Occupations --- Central Nervous System Diseases --- Diseases --- Geographicals --- Nervous System Diseases --- Mental Disorders --- Psychiatry and Psychology --- Biology --- Health & Biological Sciences --- Microbiology & Immunology --- Cattle --- Virus diseases. --- BSE (Disease) --- Mad cow disease --- Spongiform encephalopathy, Bovine --- Medicine. --- Epistemology. --- Logic. --- Philosophy and science. --- Epidemiology. --- Medicine & Public Health. --- Philosophy of Science. --- Medicine/Public Health, general. --- Prion diseases in animals --- Creutzfeldt-Jakob disease --- Virus diseases --- Genetic epistemology. --- Philosophy. --- Argumentation --- Deduction (Logic) --- Deductive logic --- Dialectic (Logic) --- Logic, Deductive --- Intellect --- Psychology --- Thought and thinking --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Developmental psychology --- Knowledge, Theory of --- Normal science --- Philosophy of science --- Public health --- Methodology --- Health Workforce --- Epistemology --- Theory of knowledge --- Science and philosophy --- Knowledge, Theory of. --- Medical sciences. --- Health Sciences. --- Basic medical sciences --- Basic sciences, Medical --- Biomedical sciences --- Health sciences --- Preclinical sciences --- Sciences, Medical
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Through the discovery of the link between Acinetobacter bacteria in Multiple Sclerosis patients and Bovine Spongiform Encephalopathy affected animals, the author brings together a comprehensive look at the cause of MS throughout the world. Multiple Sclerosis, Mad Cow Disease and Acinetobacter delves into the cause of these two neurological diseases, MS and BSE, and elaborates on their relation through exposure to a common microbe: Acinetobacter, found in human sinuses, on the skin and in the soil. Multiple Sclerosis, Mad Cow Disease and Acinetobacter informs the reader that multiple sclerosis may be linked to the microbe Acinetobacter, which carries molecular structures resembling myelin, the outer sheath covering of neurones. This book will be of interest to international scientific and medical communities, as well as accessible to patients, neurologists, research institutes and the general public.
Biomedicine. --- Antibodies. --- Immunology. --- Infectious Diseases. --- Veterinary Medicine. --- Medicine. --- Monoclonal antibodies. --- Emerging infectious diseases. --- Veterinary medicine. --- Médecine --- Immunologie --- Anticorps monoclonaux --- Maladies infectieuses émergentes --- Médecine vétérinaire --- Biology --- Health & Biological Sciences --- Microbiology & Immunology --- Multiple sclerosis. --- Bovine spongiform encephalopathy. --- Acinetobacter. --- Colloides --- Herella --- Mimae --- BSE (Disease) --- Mad cow disease --- Spongiform encephalopathy, Bovine --- MS (Disease) --- Sclerosis, Multiple --- Infectious diseases. --- Neisseriaceae --- Cattle --- Prion diseases in animals --- Creutzfeldt-Jakob disease --- Demyelination --- Myelin sheath --- Virus diseases --- Diseases --- Veterinary Medicine/Veterinary Science. --- Farriery --- Large animal medicine --- Large animal veterinary medicine --- Livestock medicine --- Veterinary science --- Medicine --- Animal health --- Animals --- Domestic animals --- Livestock --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Immunobiology --- Life sciences --- Serology --- Antibodies, Monoclonal --- Monoclonal immunoglobulins --- Immunoglobulins --- Molecular cloning --- Losses --- Antibodies --- Immune globulins --- Immune serum globulin --- Blood proteins --- Globulins --- Plasma cells --- Antibody diversity --- Antigens --- Bacterial immunoglobulin-binding proteins
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Food science and technology --- European Union --- BSE (Disease) --- BSE (Maladie) --- BSE (Ziekte) --- Bovine spongiform encephalopathy --- Encéphalopathie spongiforme bovine --- Gekkekoeienziekte --- Maladie de la vache folle --- Maladie des vaches folles --- Spongiform encephalopathy [Bovine ] --- Vache folle [Maladie de la ] --- Vaches folles [Maladies des ] --- Food --- Food industry and trade --- Aliments --- Safety measures --- Safety regulations --- Sécurité --- Mesures --- Industrie et commerce --- Règlements --- Produit alimentaire --- foods --- Industrie alimentaire --- Food industry --- Santé publique --- public health --- Production végétale intégrée --- integrated plant production --- Production animale --- Animal production --- Protection du consommateur --- consumer protection --- -Food industry and trade --- -Foods --- Dinners and dining --- Home economics --- Table --- Cooking --- Diet --- Dietaries --- Gastronomy --- Nutrition --- Mad cow disease --- Spongiform encephalopathy, Bovine --- Cattle --- Prion diseases in animals --- Creutzfeldt-Jakob disease --- Food preparation --- Food preparation industry --- Food processing --- Food processing industry --- Food trade --- Agricultural processing industries --- Processed foods --- -Safety regulations --- -Virus diseases --- -Safety measures --- -Bovine spongiform encephalopathy --- -BSE (Disease) --- Foods --- -Food --- Sécurité --- Règlements --- Virus diseases --- Food technology --- Processing --- Primitive societies --- Food industry and trade - Safety regulations - European Union countries --- Food - Safety measures - European Union countries --- CONSOMMATEURS ET CONSOMMATION --- PROTECTION
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Statistical Aspects of BSE: Models for an Epidemic presents the general methodology required for thorough analysis and modeling of novel long incubation diseases with largely unknown etiology. BSE in Great Britain cattle is the primary example system presented, but application to other diseases, particularly the transmissible spongiform encephalopathies (e.g., Scrapie in sheep and nvCJD in humans) are also highlighted. Adopting a reasonably mathematically rigorous style, the book concentrates on presenting an exposition of the "state-of-the-art" rather than introductory material on the mathematical/statistical modeling of infectious diseases.Marketing Class Code:
Mathematical statistics --- Prion Diseases --- Prion Diseases. --- Encephalopathy, Bovine Spongiform --- Creutzfeldt-Jakob Syndrome --- Epidemiology --- -Bovine spongiform encephalopathy --- -Prion diseases --- -Creutzfeldt-Jakob disease --- -Encephalopathies, Spongiform, Transmissible --- Human Transmissible Spongiform Encephalopathies, Inherited --- Inherited Human Transmissible Spongiform Encephalopathies --- Prion Disease --- Prion Protein Diseases --- Prion-Associated Disorders --- Prion-Induced Disorder --- Prion-Induced Disorders --- Transmissible Spongiform Encephalopathies --- Dementias, Transmissible --- Spongiform Encephalopathies, Transmissible --- Transmissible Dementias --- Dementia, Transmissible --- Disorder, Prion-Induced --- Disorders, Prion-Induced --- Encephalopathies, Transmissible Spongiform --- Encephalopathy, Transmissible Spongiform --- Prion Induced Disorder --- Prion Protein Disease --- Spongiform Encephalopathy, Transmissible --- Transmissible Dementia --- Transmissible Spongiform Encephalopathy --- Scrapie --- Slow Virus Diseases --- CJD (Disease) --- Creutzfeldt-Jakob syndrome --- Heidenhain syndrome --- Jakob-Creutzfeldt disease --- Jakob-Creutzfeldt syndrome --- Jakob's disease --- Spastic pseudosclerosis --- Sub-acute spongiform encephalopathy --- Subacute spongiform encephalopathy --- Central nervous system --- Presenile dementia --- Prion diseases --- Bovine spongiform encephalopathy --- Encephalopathies, Spongiform --- Prion infections --- Spongiform encephalopathies --- Transmissible spongiform encephalopathies --- Unconventional slow virus diseases --- Communicable diseases --- Slow virus diseases --- BSE (Disease) --- Mad cow disease --- Spongiform encephalopathy, Bovine --- Cattle --- Prion diseases in animals --- Creutzfeldt-Jakob disease --- Diseases --- Public health --- epidemiology. --- Statistical methods --- -Statistical methods --- Virus diseases --- Statistical methods. --- -epidemiology. --- Encephalopathies, Spongiform, Transmissible --- Epidemiology&delete& --- epidemiology
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