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Lipids represent the major players in marine organisms as the major constituents of biological membranes, with key roles in biological processes and acclimation to environmental changes. New research trends aim to contribute to improving knowledge on the role lipids in the biological matrix, understanding the impact of climate change in marine organisms, and developing new tools for chemophenotyping, traceability, and biomarkers of trophic chains in marine ecosystems, such that the nutritional value or prospective bioactive compounds can be disclosed for health applications. “Lipids in the Ocean 2021” (http://lipids2021.web.ua.pt) was originally planned to be held at the University of Aveiro and ran from 5 to 7 July 2021 (and was ultimately an online conference due to uncertainties regarding the COVID-19 situation). The aim was to go in deep into research interests covering topics related to lipids from marine organisms, such as marine lipidomics, lipids as biomarkers in trophic webs, green lipids from the ocean (seaweeds, microalgae, and macrophytes), marine lipid biotechnology, and seafood traceability using lipids—from basic research to sustainable production and applications in the food, nutraceutics, feed, cosmetics, and pharma industries. This Special Issue welcomed not only attendees of “Lipids in the Ocean 2021” to publish their latest research outcomes but also all researchers in relevant fields to share their exciting works with the community.

Public health & preventive medicine --- fatty acids --- fungal endophytes --- laminariales --- Paradendryphiella salina --- brown adipose tissue --- browning --- energy expenditure --- n-3 fatty acid --- uncoupling protein --- white adipose tissue --- krill oil --- omega-3 polyunsaturated fatty acids --- bioavailability --- nutraceuticals --- dietary supplements --- dietary resource --- Mytilus galloprovincialis --- Crassostrea gigas --- diatom --- competition --- biofouling --- EPA --- DHA --- aquafeeds --- n-3/n-6 ratio --- n-3 PUFA --- IMTA --- powdered fish oil --- docosahexaenoic acid --- chitosan nanoparticles --- encapsulation efficiency --- loading capacity --- TGA --- FTIR --- oxidative stability --- algae --- bioactivity --- glycolipids --- lipidomics --- macroalgae --- phospholipids --- seaweeds --- long-chain PUFA synthesis --- desaturases --- elongases --- PKS pathway --- 20:5n-3 (EPA) --- 22:6n-3 (DHA) --- Tisochrysis lutea --- 13C artificial enrichment --- Crypthecodinium cohnii --- omega-3 fatty acid --- biomass recycling --- dinoflagellate extract --- FTIR spectroscopy --- Krebs cycle --- central metabolism --- kinetic model --- constraint-based model

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This book aims to summarize the latest achievements in the development and manufacturing of modern biomaterials used in modern medicine and dentistry, for example, in cases where, as a result of a traffic or sports accident, aging, resection of organs after oncological surgery, or dangerous inflammation, there is a need to replace lost organs, tissues, and parts of the human body. The essence of biomedical materials is their constant contact with living tissues, organisms, or microorganisms and, therefore, they should meet numerous requirements from various fields, including medicine, biology, chemistry, tissue engineering, and materials science. For this reason, biomaterials must be compatible with the organism, and biocompatibility issues must be addressed before using the product in a clinical setting. The production and synthesis of biomaterials require the use of various technologies and methods to obtain the appropriate material, which is then processed using advanced material processing technologies. Often, however, it is necessary to directly manufacture a specific product with individualized geometric features and properties tailored to the requirements of a particular patient. In such cases, additive manufacturing methods are increasingly used. In this sense, it can be considered that the Biomaterials 4.0 stage has been reached, and detailed information is included in the individual chapters of this book on the achievements in the development and manufacturing of modern biomaterials used in modern regenerative medicine, regenerative dentistry, and tissue engineering.

Technology: general issues --- sol-gel phase transitions --- injectable scaffolds --- chitosan --- calcium β-glycerophosphate --- rheology --- bone tissue engineering --- diblock copolymers --- drug delivery systems --- nanoparticles --- nanoprecipitation --- self-assembly --- implant --- stainless steel --- nickel --- leaching --- nitrogen --- cytotoxicity --- nanodendrites --- nanostar --- fibroblast cells --- gelatin --- one-pot synthesis --- hollow mesoporous silica --- porous silica --- high drug loading capacity --- drug delivery system --- fretting --- fretting wear --- Ni-Cr-Mo --- dental alloys --- titaniumcarbonitride --- Ti(C, N) coating --- thin films --- zirconium carbide --- antimicrobial properties --- medical implants --- 316L stainless steel --- sintering --- surface nitriding --- nitrogen absorption --- response surface methodology --- sodium alginate --- hydrogel material --- regenerative medicine --- urethra --- hybrid materials --- hydroxyapatite --- FEA --- V-shaped tooth defects --- fillings --- glass-ionomer cement --- flowable composite --- stomatognathic system --- prosthetic restorations --- surgical guide --- dental prosthesis restoration manufacturing center --- CBCT tomography --- dental implants --- implant-scaffolds --- hybrid multilayer biological-engineering composites biomaterials --- CAD/CAM methods --- additive manufacturing technologies --- selective laser sintering --- stereolithography --- Dentistry 4.0 --- Industry 4.0 --- robocasting --- bioactive glass --- scaffold --- sol–gel --- 45S5 Bioglass® --- biomaterials --- biomedical implants --- additive manufacturing --- dental prosthetic restorations --- Ti6Al4V dental alloy --- structural X-ray analysis --- energy-dispersive X-ray spectroscope --- metallography --- tensile and bending strength --- corrosion resistance --- tribological tests --- in-vitro tests --- industry 4.0 --- dentistry 4.0 --- SARS-CoV-2 pandemic --- SPEC strategy --- elimination clinical aerosol at the source --- dendrological matrix --- photopolymer materials --- additive digital light printing --- dentistry sustainable development --- dental prophylaxis --- dental interventionistic treatment --- caries --- periodontology --- toothlessness --- endodontics --- dental implantology --- dental prosthetics --- dentist safety --- dentist ethics --- Co–Cr dental alloys --- corrosion --- porcelain firing --- SLM --- MSM --- CST --- light-cured composites --- photopolymerization process --- microhardness --- optimization --- regression analysis --- health --- well-being --- long and healthy life policy --- medicine --- dentistry --- medical ethics --- COVID-19 pandemic --- bioengineering --- medical engineering --- dental engineering --- biomedical materials --- Bioengineering 4.0 --- engineers’ ethics --- filling materials --- sealants --- obturation --- gutta-percha --- Resilon --- procedural benchmarking --- comparative matrices --- virtual approach --- digital twin --- scanning electron microscopy --- n/a --- sol-gel --- Co-Cr dental alloys --- engineers' ethics --- Waddawalla / Well 40 (Great Sandy Desert WA SF51-08)

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• Reference Manager
• EndNote
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This book aims to summarize the latest achievements in the development and manufacturing of modern biomaterials used in modern medicine and dentistry, for example, in cases where, as a result of a traffic or sports accident, aging, resection of organs after oncological surgery, or dangerous inflammation, there is a need to replace lost organs, tissues, and parts of the human body. The essence of biomedical materials is their constant contact with living tissues, organisms, or microorganisms and, therefore, they should meet numerous requirements from various fields, including medicine, biology, chemistry, tissue engineering, and materials science. For this reason, biomaterials must be compatible with the organism, and biocompatibility issues must be addressed before using the product in a clinical setting. The production and synthesis of biomaterials require the use of various technologies and methods to obtain the appropriate material, which is then processed using advanced material processing technologies. Often, however, it is necessary to directly manufacture a specific product with individualized geometric features and properties tailored to the requirements of a particular patient. In such cases, additive manufacturing methods are increasingly used. In this sense, it can be considered that the Biomaterials 4.0 stage has been reached, and detailed information is included in the individual chapters of this book on the achievements in the development and manufacturing of modern biomaterials used in modern regenerative medicine, regenerative dentistry, and tissue engineering.

Technology: general issues --- sol-gel phase transitions --- injectable scaffolds --- chitosan --- calcium β-glycerophosphate --- rheology --- bone tissue engineering --- diblock copolymers --- drug delivery systems --- nanoparticles --- nanoprecipitation --- self-assembly --- implant --- stainless steel --- nickel --- leaching --- nitrogen --- cytotoxicity --- nanodendrites --- nanostar --- fibroblast cells --- gelatin --- one-pot synthesis --- hollow mesoporous silica --- porous silica --- high drug loading capacity --- drug delivery system --- fretting --- fretting wear --- Ni-Cr-Mo --- dental alloys --- titaniumcarbonitride --- Ti(C, N) coating --- thin films --- zirconium carbide --- antimicrobial properties --- medical implants --- 316L stainless steel --- sintering --- surface nitriding --- nitrogen absorption --- response surface methodology --- sodium alginate --- hydrogel material --- regenerative medicine --- urethra --- hybrid materials --- hydroxyapatite --- FEA --- V-shaped tooth defects --- fillings --- glass-ionomer cement --- flowable composite --- stomatognathic system --- prosthetic restorations --- surgical guide --- dental prosthesis restoration manufacturing center --- CBCT tomography --- dental implants --- implant-scaffolds --- hybrid multilayer biological-engineering composites biomaterials --- CAD/CAM methods --- additive manufacturing technologies --- selective laser sintering --- stereolithography --- Dentistry 4.0 --- Industry 4.0 --- robocasting --- bioactive glass --- scaffold --- sol-gel --- 45S5 Bioglass® --- biomaterials --- biomedical implants --- additive manufacturing --- dental prosthetic restorations --- Ti6Al4V dental alloy --- structural X-ray analysis --- energy-dispersive X-ray spectroscope --- metallography --- tensile and bending strength --- corrosion resistance --- tribological tests --- in-vitro tests --- industry 4.0 --- dentistry 4.0 --- SARS-CoV-2 pandemic --- SPEC strategy --- elimination clinical aerosol at the source --- dendrological matrix --- photopolymer materials --- additive digital light printing --- dentistry sustainable development --- dental prophylaxis --- dental interventionistic treatment --- caries --- periodontology --- toothlessness --- endodontics --- dental implantology --- dental prosthetics --- dentist safety --- dentist ethics --- Co-Cr dental alloys --- corrosion --- porcelain firing --- SLM --- MSM --- CST --- light-cured composites --- photopolymerization process --- microhardness --- optimization --- regression analysis --- health --- well-being --- long and healthy life policy --- medicine --- dentistry --- medical ethics --- COVID-19 pandemic --- bioengineering --- medical engineering --- dental engineering --- biomedical materials --- Bioengineering 4.0 --- engineers' ethics --- filling materials --- sealants --- obturation --- gutta-percha --- Resilon --- procedural benchmarking --- comparative matrices --- virtual approach --- digital twin --- scanning electron microscopy --- Waddawalla / Well 40 (Great Sandy Desert WA SF51-08)