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2022 (3)

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Book
Osteoarthritis: From Molecular Pathways to Therapeutic Advances
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Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

In this book, we have reported the most recent discoveries and updates regarding molecular pathways in osteoarthritis. In particular, the advances regarding therapeutical options, from a molecular point of view, are largely discussed.

Keywords

Research & information: general --- Biology, life sciences --- osteoarthritis --- cartilage --- type II collagen --- matrix metalloproteinases --- MMP-13 --- regulation --- inhibitor --- NO synthase --- Interleukin-1β --- chondrocytes --- mitochondrial dysfunction --- mesenchimal stem cells --- chondrocytic commitment --- autophagy --- miRNAs --- hydrostatic pressure --- adipokines --- visfatin --- Wnt/β-catenin --- mechanical loading --- obesity --- microRNA --- oxidative stress --- vibrational spectroscopy --- near-infrared spectroscopy --- infrared spectroscopy --- Raman spectroscopy --- early diagnosis --- exercise --- physical activity --- nutraceuticals --- dietary supplements --- inflammation --- aging --- inflammaging --- osteochondral explant culture --- joint modelling --- pharmacological assay --- native tissue analysis --- hexosamine biosynthetic pathway --- cartilage trauma --- post-traumatic osteoarthritis --- O-GlcNAcylation --- glucosamine --- cell death --- therapy --- sex as a biological variable --- whole transcriptome sequencing --- molecules --- TGF-β --- SMAD2/3 signaling --- linker modifications --- meniscus --- proteomics --- MRM --- ECM --- celecoxib --- glucosamine sulfate --- chondroprotection --- NF-κB --- cytokines --- chemokines --- pathogenesis --- biomarker --- chondrocyte --- IL-1β --- IFNγ, IL-17 --- IL-4 --- RNA-Seq --- hypertrophy --- remodeling --- angiogenesis --- chondroitin --- collagen --- methylsulfonylmethane --- vitamin C --- vitamin D --- hyaluronic acid


Book
Osteoarthritis: From Molecular Pathways to Therapeutic Advances
Author:
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

In this book, we have reported the most recent discoveries and updates regarding molecular pathways in osteoarthritis. In particular, the advances regarding therapeutical options, from a molecular point of view, are largely discussed.


Book
Osteoarthritis: From Molecular Pathways to Therapeutic Advances
Author:
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

In this book, we have reported the most recent discoveries and updates regarding molecular pathways in osteoarthritis. In particular, the advances regarding therapeutical options, from a molecular point of view, are largely discussed.

Keywords

Research & information: general --- Biology, life sciences --- osteoarthritis --- cartilage --- type II collagen --- matrix metalloproteinases --- MMP-13 --- regulation --- inhibitor --- NO synthase --- Interleukin-1β --- chondrocytes --- mitochondrial dysfunction --- mesenchimal stem cells --- chondrocytic commitment --- autophagy --- miRNAs --- hydrostatic pressure --- adipokines --- visfatin --- Wnt/β-catenin --- mechanical loading --- obesity --- microRNA --- oxidative stress --- vibrational spectroscopy --- near-infrared spectroscopy --- infrared spectroscopy --- Raman spectroscopy --- early diagnosis --- exercise --- physical activity --- nutraceuticals --- dietary supplements --- inflammation --- aging --- inflammaging --- osteochondral explant culture --- joint modelling --- pharmacological assay --- native tissue analysis --- hexosamine biosynthetic pathway --- cartilage trauma --- post-traumatic osteoarthritis --- O-GlcNAcylation --- glucosamine --- cell death --- therapy --- sex as a biological variable --- whole transcriptome sequencing --- molecules --- TGF-β --- SMAD2/3 signaling --- linker modifications --- meniscus --- proteomics --- MRM --- ECM --- celecoxib --- glucosamine sulfate --- chondroprotection --- NF-κB --- cytokines --- chemokines --- pathogenesis --- biomarker --- chondrocyte --- IL-1β --- IFNγ, IL-17 --- IL-4 --- RNA-Seq --- hypertrophy --- remodeling --- angiogenesis --- chondroitin --- collagen --- methylsulfonylmethane --- vitamin C --- vitamin D --- hyaluronic acid

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