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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Medicine --- Oncology --- multiparametric MRI --- synthetic CT (sCT) --- deep learning --- MR Linac --- radiomics analysis

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This book is a comprehensive review of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT): its physics, clinical evidence, indications, and future directions. The utilization of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) is increasing internationally because of several factors. First, it offers patients a local treatment option that has demonstrated effectiveness similar to traditional surgery without the morbidity of general anesthesia and open surgical resection. Second, recent advancements in the quality of scientific evidence supporting a SRS or SBRT-containing approach in patients continues to evolve and demonstrate favorable disease-specific outcomes with little, if any, toxicity in various anatomic disease sites and for various conditions including cancer, benign tumors, and other psychiatric and neurologic conditions. Third, and most provocatively, is the notion that definitive local therapy (i.e. SRS or SBRT) in patients with cancer can boost the immune system to fight cancer in other sites throughout the body. While traditional medical knowledge would suggest that all patients with metastatic cancer are incurable, there is a mounting body of evidence that there is a subset of these patients that can be cured with definitive SRS or SBRT. This volume thus delves into each of these benefits and aspects of treatment, guiding physicians to the best treatment plan for their patients. Expert, international authors provide guidelines for SRS and SBRT use by clinicians. Chapters are divided into six main sections: Radiobiology of Radiosurgery and Stereotactic Body Radiation Therapy, Intracranial Radiosurgery Technique, Intracranial Radiosurgery by Indication, Stereotactic Body Radiation Therapy Technique, Stereotactic Body Radiation Therapy by Indication, The Future of Radiosurgery and SBRT. Overall physics are explained, as well as specific considerations for particular surgical tools (including the Leksell Gamma Knife and Accuray CyberKnife), techniques (including fractionated and charged particle radiosurgery), and anatomic sites (including brain metastases, pituitary tumors, and the prostate). Detailed images and charts enhance the chapters. This book provides physicians with a single, practical resource incorporating both of these broad categories of treatment, SRS and SBRT, and better defines the current role and the direction of radiosurgery.

Radiotherapy. --- Radiosurgery. --- Radiotherapy. --- CyberKnife Radiosurgery --- LINAC Radiosurgery --- Radiosurgery, Gamma Knife --- Radiosurgery, Linear Accelerator --- Radiosurgery, Stereotactic --- Stereotactic Radiation --- Stereotactic Radiation Therapy --- Gamma Knife Radiosurgery --- Linear Accelerator Radiosurgery --- Stereotactic Body Radiotherapy --- Stereotactic Radiosurgery --- CyberKnife Radiosurgeries --- Gamma Knife Radiosurgeries --- LINAC Radiosurgeries --- Linear Accelerator Radiosurgeries --- Radiation Therapy, Stereotactic --- Radiation, Stereotactic --- Radiosurgery, CyberKnife --- Radiosurgery, LINAC --- Radiotherapy, Stereotactic Body --- Stereotactic Body Radiotherapies --- Stereotactic Radiation Therapies --- Stereotactic Radiations --- Stereotactic Radiosurgeries --- Therapy, Stereotactic Radiation --- Particle Accelerators --- Radiotherapy, Conformal --- Radiation therapy --- Electrotherapeutics --- Hospitals --- Medical electronics --- Medical radiology --- Therapeutics, Physiological --- Phototherapy --- Radiological services

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The THz region of the electromagnetic spectrum is a frontier research area involving application of many disciplines, from outdoor to indoor communications, security, drug detection, biometrics, food quality control, agriculture, medicine, semiconductors, and air pollution. THz research is highly demanding in term of sources with high power and time resolution, detectors, and new spectrometer systems. Many open questions still exist regarding working at THz frequencies; many materials exhibit unusual or exotic properties in the THz domain, and researchers need new methodologies to exploit these opportunities. This book contains original papers dealing with emerging applications, new devices, sources and detectors, and materials with advanced properties for applications in biomedicine, cultural heritage, technology, and space.

terahertz --- free electron laser --- energy recovery --- THz spectroscopy --- free-electron-lasers --- nonlinear optics --- THz --- waveguide spectroscopy --- coating materials --- particle accelerators --- leaky-wave antennas --- metasurface --- liquid crystals --- graphene --- FEL --- copper --- damage --- surface --- coherent synchrotron radiation --- low alpha --- cross-correlation --- pump-probe --- terahertz spectroscopy --- terahertz time-domain spectroscopy --- terahertz pulsed imaging --- near-field imaging --- biomedical imaging --- cancer diagnosis --- endoscopy --- infrared analysis --- microspectroscopy --- cultural heritage --- synchrotron radiation --- niobium --- proximity effects --- superconductivity --- detectors --- Vortex dynamics --- bunch length --- linac --- far infrared --- spectroscopy --- imaging --- THz source --- high-brightness electron beams --- laser comb technique --- optical indices --- nonlinear effects --- optical rectification --- organic crystals --- HMQ-TMS --- waveguides --- THz detector --- THz imaging

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The THz region of the electromagnetic spectrum is a frontier research area involving application of many disciplines, from outdoor to indoor communications, security, drug detection, biometrics, food quality control, agriculture, medicine, semiconductors, and air pollution. THz research is highly demanding in term of sources with high power and time resolution, detectors, and new spectrometer systems. Many open questions still exist regarding working at THz frequencies; many materials exhibit unusual or exotic properties in the THz domain, and researchers need new methodologies to exploit these opportunities. This book contains original papers dealing with emerging applications, new devices, sources and detectors, and materials with advanced properties for applications in biomedicine, cultural heritage, technology, and space.

Research & information: general --- terahertz --- free electron laser --- energy recovery --- THz spectroscopy --- free-electron-lasers --- nonlinear optics --- THz --- waveguide spectroscopy --- coating materials --- particle accelerators --- leaky-wave antennas --- metasurface --- liquid crystals --- graphene --- FEL --- copper --- damage --- surface --- coherent synchrotron radiation --- low alpha --- cross-correlation --- pump-probe --- terahertz spectroscopy --- terahertz time-domain spectroscopy --- terahertz pulsed imaging --- near-field imaging --- biomedical imaging --- cancer diagnosis --- endoscopy --- infrared analysis --- microspectroscopy --- cultural heritage --- synchrotron radiation --- niobium --- proximity effects --- superconductivity --- detectors --- Vortex dynamics --- bunch length --- linac --- far infrared --- spectroscopy --- imaging --- THz source --- high-brightness electron beams --- laser comb technique --- optical indices --- nonlinear effects --- optical rectification --- organic crystals --- HMQ-TMS --- waveguides --- THz detector --- THz imaging --- terahertz --- free electron laser --- energy recovery --- THz spectroscopy --- free-electron-lasers --- nonlinear optics --- THz --- waveguide spectroscopy --- coating materials --- particle accelerators --- leaky-wave antennas --- metasurface --- liquid crystals --- graphene --- FEL --- copper --- damage --- surface --- coherent synchrotron radiation --- low alpha --- cross-correlation --- pump-probe --- terahertz spectroscopy --- terahertz time-domain spectroscopy --- terahertz pulsed imaging --- near-field imaging --- biomedical imaging --- cancer diagnosis --- endoscopy --- infrared analysis --- microspectroscopy --- cultural heritage --- synchrotron radiation --- niobium --- proximity effects --- superconductivity --- detectors --- Vortex dynamics --- bunch length --- linac --- far infrared --- spectroscopy --- imaging --- THz source --- high-brightness electron beams --- laser comb technique --- optical indices --- nonlinear effects --- optical rectification --- organic crystals --- HMQ-TMS --- waveguides --- THz detector --- THz imaging