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Ankle --- Diabetes --- Diabetic Foot --- Foot --- Limb Salvage. --- Reconstructive Surgical Procedures --- Surgery. --- Methods.

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This book provides a practical guide to the treatment of patients as risk from limb amputation. The most common presentations of the diabetic foot are presented in concise and evidence-based chapters covering the neuropathic foot, the Charcot foot, the ischemic foot, and the infected foot. Each section includes an introduction to the clinical approach as well as an algorithm illustrating the limb salvage pathway and intervention steps. Limb Salvage of the Diabetic Foot: An Interdisciplinary Approach aims to help the reader build an interdisciplinary understanding of the diabetic foot and its treatment and is of interest to all members of the interdisciplinary diabetic foot team including surgeons, podiatrists, radiologists, nurses, orthotists, infectious disease physicians, and endocrinologists.

Endocrinology. --- Surgery. --- Surgery, Primitive --- Medicine --- Internal medicine --- Hormones --- Endocrinology . --- Diabetes --- Limb salvage. --- Complications. --- Limb-saving surgery --- Limb-sparing surgery --- Salvage of limbs --- Extremities (Anatomy) --- Therapeutics, Surgical --- Surgery --- Complications and sequelae

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Steven A. Rosenberg, MD In the past two decades significant progress has quality of life. The use of local radiation therapy has occurred, in the management of patients with mus- had a profound impact on the ability to achieve local loskeletal cancers, that has improved both the survival control. Cooperation between surgeons and radiation and the quality of life of afflicted patients. Changes in therapists often results in the tailoring of surgical p- the management of these patients have mirrored cedures to maximize the combined application of these trends in the entire field of oncology. two effective treatment modalities. Although impact on The most significant change has been improvement overall survival has not been demonstrated due to the in the surgical techniques for the resection of musculo- addition of radiation therapy, important advances in skeletal cancers based on a detailed understanding of improving the quality of life of patients receiving this the anatomic features of each particular tumor site, as combined-modality treatment have been evident. well as an appreciation of the natural biology that affects A third change impacting on the survival of patients the local spread of these tumors. The current volume of with musculoskeletal cancers has been the aggressive Musculoskeletal Cancer Surgery: Treatment of Sarcomas and resection of metastatic deposits.

Musculoskeletal system --- Sarcoma --- Muscles --- Soft tissue tumors --- Cancer --- Surgery. --- Orthopedics. --- Surgical oncology. --- Oncology  . --- Surgical Oncology. --- General Surgery. --- Pediatric Surgery. --- Oncology. --- Pediatric surgery. --- Tumors --- Pediatric surgery --- Surgery, Pediatric --- Children --- Surgery, Primitive --- Medicine --- Oncologic surgery --- Oncological surgery --- Surgical oncology --- Orthopaedics --- Orthopedia --- Surgery --- Diseases --- Treatment --- Excision --- Limb salvage. --- Limb-saving surgery --- Limb-sparing surgery --- Salvage of limbs --- Extremities (Anatomy) --- Therapeutics, Surgical

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Most of the treatments in medicine are patient specific, aren’t they? So why should we bother with individualizing implants if we adapt our therapy to patients anyway? Looking at the neighboring field of oncologic treatment, you would not question the fact that individualization of tumor therapy with personalized antibodies has led to the thriving of this field in terms of success in patient survival and positive responses to alternatives for conventional treatments. Regarding the latest cutting-edge developments in orthopedic surgery and biotechnology, including new imaging techniques and 3D-printing of bone substitutes as well as implants, we do have an armamentarium available to stimulate the race for innovation in medicine. This Special Issue of Journal of Personalized Medicine will gather all relevant new and developed techniques already in clinical practice. Examples include the developments in revision arthroplasty and tumor (pelvic replacement) surgery to recreate individual defects, individualized implants for primary arthroplasty to establish physiological joint kinematics, and personalized implants in fracture treatment, to name but a few.

patient specific implant --- custom made implant --- revision hip --- Paprosky --- pelvic discontinuity --- highly cancellous --- implant surface --- tibia --- titanium alloy --- 3D printing --- megaendoprosthesis --- orthopedic oncology --- limb salvage --- patient safety management --- vascular bypass --- soft tissue sarcoma --- vascular reconstruction --- shoulder arthroplasty --- X-ray images --- implant classification --- deep learning --- dense residual ensemble-network --- rotational invariant augmentation --- Three-Dimensional Printing (3DP) --- custom implant --- patient-specific implants (PSI) --- spinal surgery --- total knee replacement --- total knee arthroplasty --- kinematic alignment --- slope --- rotation --- navigation-assisted surgery --- tumor orthopedics --- oncologic orthopedics --- patient specific --- tumor surgery --- bone defects --- hip detection --- deep convolutional neural network --- radiography --- leg alignment --- patient-specific instruments --- custom-made implant --- rotational correction --- custom-made --- rTKA --- 3D-printed --- individual --- limb-salvage --- cone --- customised --- personalised --- knee replacement --- native knee morphology --- femoral J-Curve --- principal component analysis --- geometric parameter analysis --- individualized alignment --- restricted kinematic alignment --- robotic-assisted TKA --- MAKO --- safe zone --- pelvic tumors --- 3D printed prostheses --- computer aided design pelvic reconstruction --- arthroplasty --- complications --- bone tumor --- pelvis --- patient-specific --- individualized --- 3D-printing --- unicondylar knee arthroplasty --- unicompartmental knee replacement --- unicondylar knee replacement --- partial knee arthroplasty --- partial knee replacement --- UKA --- UKR --- augmented reality --- image-guided surgery --- intraoperative imaging --- simulation --- mixed reality --- reversed shoulder arthroplasty --- 3D planning --- total hip arthroplasty --- finite element method --- cemented and uncemented acetabular fixation --- polyethylene wear patterns --- cervical–diaphyseal angle --- center of rotation --- material head --- size head --- liner thickness --- preoperative planning --- patient-specific THA --- target zone --- leg length discrepancy --- range of motion --- edge loading --- TKA --- tricompartmental knee osteoarthritis --- iTotal --- n/a --- cervical-diaphyseal angle

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Most of the treatments in medicine are patient specific, aren’t they? So why should we bother with individualizing implants if we adapt our therapy to patients anyway? Looking at the neighboring field of oncologic treatment, you would not question the fact that individualization of tumor therapy with personalized antibodies has led to the thriving of this field in terms of success in patient survival and positive responses to alternatives for conventional treatments. Regarding the latest cutting-edge developments in orthopedic surgery and biotechnology, including new imaging techniques and 3D-printing of bone substitutes as well as implants, we do have an armamentarium available to stimulate the race for innovation in medicine. This Special Issue of Journal of Personalized Medicine will gather all relevant new and developed techniques already in clinical practice. Examples include the developments in revision arthroplasty and tumor (pelvic replacement) surgery to recreate individual defects, individualized implants for primary arthroplasty to establish physiological joint kinematics, and personalized implants in fracture treatment, to name but a few.

Medicine --- patient specific implant --- custom made implant --- revision hip --- Paprosky --- pelvic discontinuity --- highly cancellous --- implant surface --- tibia --- titanium alloy --- 3D printing --- megaendoprosthesis --- orthopedic oncology --- limb salvage --- patient safety management --- vascular bypass --- soft tissue sarcoma --- vascular reconstruction --- shoulder arthroplasty --- X-ray images --- implant classification --- deep learning --- dense residual ensemble-network --- rotational invariant augmentation --- Three-Dimensional Printing (3DP) --- custom implant --- patient-specific implants (PSI) --- spinal surgery --- total knee replacement --- total knee arthroplasty --- kinematic alignment --- slope --- rotation --- navigation-assisted surgery --- tumor orthopedics --- oncologic orthopedics --- patient specific --- tumor surgery --- bone defects --- hip detection --- deep convolutional neural network --- radiography --- leg alignment --- patient-specific instruments --- custom-made implant --- rotational correction --- custom-made --- rTKA --- 3D-printed --- individual --- limb-salvage --- cone --- customised --- personalised --- knee replacement --- native knee morphology --- femoral J-Curve --- principal component analysis --- geometric parameter analysis --- individualized alignment --- restricted kinematic alignment --- robotic-assisted TKA --- MAKO --- safe zone --- pelvic tumors --- 3D printed prostheses --- computer aided design pelvic reconstruction --- arthroplasty --- complications --- bone tumor --- pelvis --- patient-specific --- individualized --- 3D-printing --- unicondylar knee arthroplasty --- unicompartmental knee replacement --- unicondylar knee replacement --- partial knee arthroplasty --- partial knee replacement --- UKA --- UKR --- augmented reality --- image-guided surgery --- intraoperative imaging --- simulation --- mixed reality --- reversed shoulder arthroplasty --- 3D planning --- total hip arthroplasty --- finite element method --- cemented and uncemented acetabular fixation --- polyethylene wear patterns --- cervical-diaphyseal angle --- center of rotation --- material head --- size head --- liner thickness --- preoperative planning --- patient-specific THA --- target zone --- leg length discrepancy --- range of motion --- edge loading --- TKA --- tricompartmental knee osteoarthritis --- iTotal --- patient specific implant --- custom made implant --- revision hip --- Paprosky --- pelvic discontinuity --- highly cancellous --- implant surface --- tibia --- titanium alloy --- 3D printing --- megaendoprosthesis --- orthopedic oncology --- limb salvage --- patient safety management --- vascular bypass --- soft tissue sarcoma --- vascular reconstruction --- shoulder arthroplasty --- X-ray images --- implant classification --- deep learning --- dense residual ensemble-network --- rotational invariant augmentation --- Three-Dimensional Printing (3DP) --- custom implant --- patient-specific implants (PSI) --- spinal surgery --- total knee replacement --- total knee arthroplasty --- kinematic alignment --- slope --- rotation --- navigation-assisted surgery --- tumor orthopedics --- oncologic orthopedics --- patient specific --- tumor surgery --- bone defects --- hip detection --- deep convolutional neural network --- radiography --- leg alignment --- patient-specific instruments --- custom-made implant --- rotational correction --- custom-made --- rTKA --- 3D-printed --- individual --- limb-salvage --- cone --- customised --- personalised --- knee replacement --- native knee morphology --- femoral J-Curve --- principal component analysis --- geometric parameter analysis --- individualized alignment --- restricted kinematic alignment --- robotic-assisted TKA --- MAKO --- safe zone --- pelvic tumors --- 3D printed prostheses --- computer aided design pelvic reconstruction --- arthroplasty --- complications --- bone tumor --- pelvis --- patient-specific --- individualized --- 3D-printing --- unicondylar knee arthroplasty --- unicompartmental knee replacement --- unicondylar knee replacement --- partial knee arthroplasty --- partial knee replacement --- UKA --- UKR --- augmented reality --- image-guided surgery --- intraoperative imaging --- simulation --- mixed reality --- reversed shoulder arthroplasty --- 3D planning --- total hip arthroplasty --- finite element method --- cemented and uncemented acetabular fixation --- polyethylene wear patterns --- cervical-diaphyseal angle --- center of rotation --- material head --- size head --- liner thickness --- preoperative planning --- patient-specific THA --- target zone --- leg length discrepancy --- range of motion --- edge loading --- TKA --- tricompartmental knee osteoarthritis --- iTotal