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Polyfunctional Cytokines: IL-6 and LIF Chairman: D. Metcalf 1992 Interleukin 6 (IL-6) and leukaemia inhibitory factor (LIF) have a complex array of biological actions on diverse tissues; they share a number of functional activities, but also show some interesting differences. Although these two cytokines have much in common they are not usually considered together. The purpose of this symposium was to bring together experts from a variety of areas to discuss and compare IL-6 and LIF, to provide a new understanding of their modes of action and to assess the significance of their polyfunctionality-why the body chose to use one molecule to regulate a variety of cell types-and their functional overlap. The structure of the genes encoding IL-6 and LIF and the regulation of gene expression are described. The molecular biology, distribution and binding properties of the receptors for the two factors are discussed. The extent to which these molecular characteristics form a basis for cytokine pleiotropy and redundancy is considered. Other topics focused on include actions of IL-6 and LIF on lymphoid populations, on megakaryocyte and platelet production, on bone metabolism, on acute-phase protein synthesis by liver cells and on the nervous system-neuronal differentiation in particular. Effects of IL-6 and LIF on leukaemic cells, the role of IL-6 in plasmacytomagenesis and the potential clinical value of measurement of cytokine levels, such as in the diagnosis of intra-amniotic infection in women with preterm labour, are also covered. Related Ciba Foundation Symposia: No. 157 Clinical applications of TGF-ß Chairman: M. B. Sporn 1991 ISBN 0471 92811 9 No. 148 Molecular control of haemopoiesis Chairman: D. Metcalf 1990 ISBN 0471 92561 6 No. 147 IgE, mast cells and the allergic response Chairman: H. Metzger 1989 ISBN 0 471 92309 5 No. 131 Tumour necrosis factor and related cytotoxins Chairman: L. J. Old 1987 ISBN 0 471 91097 X
Interleukin-6 --- Leukemia inhibitory factor --- Growth Inhibitors --- Leukemia --- Congresses. --- pharmacology --- congresses. --- physiopathology --- Congresses --- Interleukin-6 - Congresses. --- Leukemia inhibitory factor - Congresses. --- Pharmacology --- Physiopathology --- Growth Inhibitors - pharmacology - congresses. --- Interleukin-6 - pharmacology - congresses --- Leukemia - physiopathology - congresses
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Sport modalities are highly practiced in order to improve many aspects of human beings, including performance and health. The increasing interest in the quantitative and qualitative aspects of sport training is ascribable to the fact that several training systems and new methodologies are appearing in all sport modalities. These methodologies can have different effects on the organism depending on the degree of training.On the other hand, some of the main objectives in sport research are to describe match activity and to detect effective performance indicators. A better knowledge of players' performance adaptations and game dynamics during competition is extremely useful for optimizing the training process. The need to develop training methodologies according to actions occurring during the game is essential for each sport.
Medicine --- hormones --- LH --- testosterone --- cortisol --- insulin --- athletes --- body alignment --- static balance --- dynamic balance --- basketball --- mouthguard --- microalgae --- soccer --- ergogenic --- ventilatory threshold --- racket sports --- technique --- performance analysis --- tactics --- sport --- vision --- performance --- racquet sports --- professional sport --- game actions --- trace mineral --- runners --- overuse injury --- biomechanics --- home-based exercise --- sustainable development --- SWOT-AHP --- physical activities --- public health --- COVID-19 --- intelligent sports --- iliopsoas --- rectus femoris --- mobility --- flexibility --- tennis --- movement --- physical tests --- athletic performance --- youth sports --- females --- football --- NIRS --- muscle oxygen saturation --- workload --- physiological adaptations --- fatigue and sport performance --- technical indicators --- tactical indicators --- paddle tennis --- trail running --- jump --- neuromuscular --- hydration --- sport vision --- social media --- social network analysis --- Altmetric --- padel --- sports competition --- myokines --- BDNF --- leukemia inhibitory factor --- irisin --- n/a --- running --- economic factors --- sport events --- expertise --- inertial sensors --- kinematic analysis --- perception-action coupling --- visual fixation --- pedaling rate --- pedaling frequency --- fatigability --- EMG --- strength --- water sport --- endurance --- origin --- nationality
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Sport modalities are highly practiced in order to improve many aspects of human beings, including performance and health. The increasing interest in the quantitative and qualitative aspects of sport training is ascribable to the fact that several training systems and new methodologies are appearing in all sport modalities. These methodologies can have different effects on the organism depending on the degree of training.On the other hand, some of the main objectives in sport research are to describe match activity and to detect effective performance indicators. A better knowledge of players' performance adaptations and game dynamics during competition is extremely useful for optimizing the training process. The need to develop training methodologies according to actions occurring during the game is essential for each sport.
hormones --- LH --- testosterone --- cortisol --- insulin --- athletes --- body alignment --- static balance --- dynamic balance --- basketball --- mouthguard --- microalgae --- soccer --- ergogenic --- ventilatory threshold --- racket sports --- technique --- performance analysis --- tactics --- sport --- vision --- performance --- racquet sports --- professional sport --- game actions --- trace mineral --- runners --- overuse injury --- biomechanics --- home-based exercise --- sustainable development --- SWOT-AHP --- physical activities --- public health --- COVID-19 --- intelligent sports --- iliopsoas --- rectus femoris --- mobility --- flexibility --- tennis --- movement --- physical tests --- athletic performance --- youth sports --- females --- football --- NIRS --- muscle oxygen saturation --- workload --- physiological adaptations --- fatigue and sport performance --- technical indicators --- tactical indicators --- paddle tennis --- trail running --- jump --- neuromuscular --- hydration --- sport vision --- social media --- social network analysis --- Altmetric --- padel --- sports competition --- myokines --- BDNF --- leukemia inhibitory factor --- irisin --- n/a --- running --- economic factors --- sport events --- expertise --- inertial sensors --- kinematic analysis --- perception-action coupling --- visual fixation --- pedaling rate --- pedaling frequency --- fatigability --- EMG --- strength --- water sport --- endurance --- origin --- nationality
Choose an application
Sport modalities are highly practiced in order to improve many aspects of human beings, including performance and health. The increasing interest in the quantitative and qualitative aspects of sport training is ascribable to the fact that several training systems and new methodologies are appearing in all sport modalities. These methodologies can have different effects on the organism depending on the degree of training.On the other hand, some of the main objectives in sport research are to describe match activity and to detect effective performance indicators. A better knowledge of players' performance adaptations and game dynamics during competition is extremely useful for optimizing the training process. The need to develop training methodologies according to actions occurring during the game is essential for each sport.
Medicine --- hormones --- LH --- testosterone --- cortisol --- insulin --- athletes --- body alignment --- static balance --- dynamic balance --- basketball --- mouthguard --- microalgae --- soccer --- ergogenic --- ventilatory threshold --- racket sports --- technique --- performance analysis --- tactics --- sport --- vision --- performance --- racquet sports --- professional sport --- game actions --- trace mineral --- runners --- overuse injury --- biomechanics --- home-based exercise --- sustainable development --- SWOT-AHP --- physical activities --- public health --- COVID-19 --- intelligent sports --- iliopsoas --- rectus femoris --- mobility --- flexibility --- tennis --- movement --- physical tests --- athletic performance --- youth sports --- females --- football --- NIRS --- muscle oxygen saturation --- workload --- physiological adaptations --- fatigue and sport performance --- technical indicators --- tactical indicators --- paddle tennis --- trail running --- jump --- neuromuscular --- hydration --- sport vision --- social media --- social network analysis --- Altmetric --- padel --- sports competition --- myokines --- BDNF --- leukemia inhibitory factor --- irisin --- running --- economic factors --- sport events --- expertise --- inertial sensors --- kinematic analysis --- perception-action coupling --- visual fixation --- pedaling rate --- pedaling frequency --- fatigability --- EMG --- strength --- water sport --- endurance --- origin --- nationality
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