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This book aims to provide novel insights into the mechanisms of embryo implantation and placental development, as well as at present an overview of the current knowledge on the different signaling pathways regulating the early steps of implantation and placentation, and on the pathological alterations which may impair the establishment of a physiological pregnancy.

Research & information: general --- Biology, life sciences --- fetuin-A --- GDM --- cell growth --- centrosome --- primary cilium --- autophagy --- implantation --- endometrium --- blastocyst --- embryo --- chorionic gonadotropin --- progesterone --- Notch --- cytokines --- placenta --- amino acid transporter --- mammalian target of rapamycin --- gestational diabetes --- trophectoderm --- cell proliferation --- let-7 miRNAs --- gene regulation --- fractalkine --- trophoblast --- bilaminar co-culture --- miRNA --- trophoblast cells --- ARID3B complex --- decidualization --- adverse pregnancy outcome --- preconception --- preimplantation genetic screening --- in-vitro fertilization --- biopsy --- euploid embryo --- pregnancy --- mosaicism --- development --- flow culture --- KIT receptor --- KITD816V --- placental development --- premature differentiation --- trophoblast stem cell --- trophoblast giant cell --- spongiotrophoblast --- invasion --- embryonic growth retardation --- Jag1 --- Dll4 --- endothelial cells --- decidua --- angiogenesis --- capillaries --- spiral arteries --- Stabilin-1 --- Stabilin-2 --- double knockout --- hemorrhage --- RNA-seq --- ChIP-seq --- enhancers --- transcription factors --- PLAGL1 --- tube formation --- blood vessel development --- PlGF --- Flt-1/VEGFR1 --- immune modulation --- human placenta --- lopinavir --- mitochondria --- Mfn2 --- UPR --- IRE1α --- placental dysfunction --- assisted reproduction techniques --- infertility --- preeclampsia --- intrauterine growth restriction --- trophoblast invasion --- sFLT-1 --- EGFL7 --- placenta-derived mesenchymal stromal cells --- mouse model