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In the past few years, knowledge about glaucoma diagnosis and follow up has evolved dramatically through advances in intraocular pressure (IOP) measurement, corneal biomechanics, structural and functional assessment of the ocular surface, anterior chamber, retina, optic nerve and intracranial visual pathways, as well as the advent of artificial intelligence. In addition, the development of new modalities of IOP-lowering and non-IOP-lowering drugs, alternative deliveries, refined laser technologies, and minimally invasive glaucoma surgery (MIGS) techniques with different implants have widened the therapeutic possibilities for treating this disease. Finally, current insights into risk factors and quality of life in relation to glaucomatous impairment are emerging. The purpose of this Special Issue is to present the latest exciting clinical developments that are taking place in the field of glaucoma.

ripasudil --- suture trabeculotomy ab interno --- Schlemm’s canal incision --- aqueous outflow --- open-angle glaucoma --- glaucoma --- inflammation --- oxidative stress --- phenotype --- polymorphism --- susceptibility --- intraocular pressure --- ocular inflammation --- cornea biomechanics --- Corvis® ST --- subclinical keratoconus --- ocular hypertension --- tears --- miRNAs --- next generation sequencing --- biomarkers --- genes --- signaling pathways --- apoptosis --- neurodegeneration --- glaucoma suspect --- lamina cribrosa --- optical coherence tomography angiography --- peripapillary vessel density --- OCTA --- vessel density --- disc --- peripapillary --- NTG --- BRVO --- corneal hysteresis --- corneal biomechanics --- ocular biomarkers --- deep learning --- perimetry --- optic nerve --- obesity --- risk factor --- young adults --- multifocal visual evoked potentials --- mfVEP --- physical exercise --- sport --- acrobatic gymnastics --- baseline intraocular pressure --- central corneal thickness --- ocular health --- tumbling skills --- hand balance --- cytokines --- BDNF --- VEGF --- fractalkine --- microglia --- saffron --- crocin --- retinal glial cells --- microperimetry --- OCT --- macula --- structure --- function --- correlation --- retina --- inner --- outer --- macular segmentation --- optical coherence tomography-angiography --- vascular density --- blood flow --- biomarker --- myopia --- n/a --- Schlemm's canal incision