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Amino Acids, Dicarboxylic --- Central Nervous System --- Disease Models, Animal. --- Kainic Acid. --- Neurotoxins --- Pyrrolidines --- toxicity. --- drug effects. --- toxicity. --- toxicity.
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"This volume critically examines the functional actions of the kainate type glutamate receptors (KARs). Following on from the larger body of work on the NMDA and AMPA-type ionotropic glutamate receptors (GluRs), studies with KARs have consistently thrown up exceptions to general rules about synaptic modulation. Contributors herein provide an insight to the idiosyncracies that now almost typify the KAR field. The fascinating insights provided in this volume serve to encourage searching mechanistic questions"--Provided by publisher.
Cellular signal transduction. --- Cerebrum -- physiology. --- Kainic acid -- Physiological effect. --- Kainic acid -- Receptors. --- Receptors, Kainic Acid -- physiology. --- Signal Transduction -- physiology. --- Kainic acid --- Cellular signal transduction --- Receptors, Ionotropic Glutamate --- Cell Physiological Processes --- Biological Science Disciplines --- Biochemical Processes --- Telencephalon --- Ligand-Gated Ion Channels --- Prosencephalon --- Cell Physiological Phenomena --- Natural Science Disciplines --- Chemical Processes --- Biochemical Phenomena --- Receptors, Glutamate --- Chemical Phenomena --- Ion Channels --- Receptors, Amino Acid --- Phenomena and Processes --- Brain --- Disciplines and Occupations --- Membrane Glycoproteins --- Membrane Transport Proteins --- Receptors, Neurotransmitter --- Central Nervous System --- Membrane Proteins --- Carrier Proteins --- Nervous System --- Receptors, Cell Surface --- Proteins --- Anatomy --- Amino Acids, Peptides, and Proteins --- Chemicals and Drugs --- Cerebrum --- Receptors, Kainic Acid --- Signal Transduction --- Physiology --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Physiological effect --- Receptors --- Physiological effect. --- Receptors. --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Digenic acid --- Medicine. --- Molecular biology. --- Biomedicine. --- Biomedicine general. --- Molecular Medicine. --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Bioenergetics --- Cellular control mechanisms --- Information theory in biology --- Amino acids --- Anthelmintics --- Neurotoxic agents --- Pyrrolidine --- Health Workforce --- Biomedicine, general.
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The G.B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far-Eastern Branch of the Russian Academy of Sciences (PIBOC FEB RAS) was founded in 1964 in Vladivostok in the Far East of Russia. Over many years, we have been carrying out studies on the natural products of both marine and terrestrial origin. In collaboration with many Russian and foreign scientists, we have investigated many hundreds of diverse biomolecules, including steroids and terpenoids, quinoid compounds and alkaloids, polysaccharides and lipids, enzymes and lectins, proteins, and peptides. The Institute has a collection of marine microorganisms (KMM) PIBOC, which includes more than 4000 strains of marine bacteria and more than 1000 strains of marine fungi. The biological activity of natural compounds is also being studied. This book includes the 14 manuscripts which covered almost all aspects of PIBOC research activity in the fields of bioorganic chemistry, biochemistry, organic synthesis of natural compounds, marine microbiology, and genetic engineering, and we hope it will provide interesting new information for scientists working in these fields.
Research & information: general --- polyhydroxylated steroids --- NMR spectra --- starfish --- Anthenoides laevigatus --- cytotoxicity --- soft agar assay --- kainic acid --- domoic acid --- dysiherbaine --- neodysiherbaine A --- marine bacteria --- whole genome sequence --- porin --- amino acids composition --- bilayer lipid membrane --- pore-forming activity --- spatial structure --- phlorotannins --- phlorethols --- anticancer activity --- colorectal cancer --- radiosensitizer --- radiotherapy --- 1,4-naphthoquinones --- quinoid compounds --- thioglycosides --- quinone-sugar conjugates --- cytotoxic activity --- antibiotic activity --- histochrome --- echinochrome A --- oxidative degradation --- HPLC–DAD–MS --- NMR --- actinoporin --- sea anemone --- Heteractis crispa --- anti-migratory activity --- glycosphingolipids --- cerebrosides --- peroxidation products --- structure elucidation --- allylic thioether --- ESI-MS --- GC-MS --- mass spectra --- glass sponge --- isomalabaricanes --- Stelletta sp. --- marine sponge --- terpenoid --- Cobetia amphilecti --- Cobetia litoralis --- Cobetia pacifica --- Cobetia marina --- Cobetia crustatorum --- identification markers --- alkaline phosphatase PhoA --- lanosterol 14-alpha demethylase --- flavonoids --- enzyme inhibition --- surface plasmon resonance --- spectral titration --- molecular docking --- Zobellia --- genomes --- polysaccharide lyase family 7 --- alginate utilization system --- paralogs --- orthologs --- recombinant phospholipase A1 --- Yersinia pseudotuberculosis --- inclusion bodies --- fusion protein --- green fluorescent protein --- porin gene expression --- antibiotic stress --- phenotypic heterogeneity --- n/a --- HPLC-DAD-MS
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The G.B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far-Eastern Branch of the Russian Academy of Sciences (PIBOC FEB RAS) was founded in 1964 in Vladivostok in the Far East of Russia. Over many years, we have been carrying out studies on the natural products of both marine and terrestrial origin. In collaboration with many Russian and foreign scientists, we have investigated many hundreds of diverse biomolecules, including steroids and terpenoids, quinoid compounds and alkaloids, polysaccharides and lipids, enzymes and lectins, proteins, and peptides. The Institute has a collection of marine microorganisms (KMM) PIBOC, which includes more than 4000 strains of marine bacteria and more than 1000 strains of marine fungi. The biological activity of natural compounds is also being studied. This book includes the 14 manuscripts which covered almost all aspects of PIBOC research activity in the fields of bioorganic chemistry, biochemistry, organic synthesis of natural compounds, marine microbiology, and genetic engineering, and we hope it will provide interesting new information for scientists working in these fields.
polyhydroxylated steroids --- NMR spectra --- starfish --- Anthenoides laevigatus --- cytotoxicity --- soft agar assay --- kainic acid --- domoic acid --- dysiherbaine --- neodysiherbaine A --- marine bacteria --- whole genome sequence --- porin --- amino acids composition --- bilayer lipid membrane --- pore-forming activity --- spatial structure --- phlorotannins --- phlorethols --- anticancer activity --- colorectal cancer --- radiosensitizer --- radiotherapy --- 1,4-naphthoquinones --- quinoid compounds --- thioglycosides --- quinone-sugar conjugates --- cytotoxic activity --- antibiotic activity --- histochrome --- echinochrome A --- oxidative degradation --- HPLC–DAD–MS --- NMR --- actinoporin --- sea anemone --- Heteractis crispa --- anti-migratory activity --- glycosphingolipids --- cerebrosides --- peroxidation products --- structure elucidation --- allylic thioether --- ESI-MS --- GC-MS --- mass spectra --- glass sponge --- isomalabaricanes --- Stelletta sp. --- marine sponge --- terpenoid --- Cobetia amphilecti --- Cobetia litoralis --- Cobetia pacifica --- Cobetia marina --- Cobetia crustatorum --- identification markers --- alkaline phosphatase PhoA --- lanosterol 14-alpha demethylase --- flavonoids --- enzyme inhibition --- surface plasmon resonance --- spectral titration --- molecular docking --- Zobellia --- genomes --- polysaccharide lyase family 7 --- alginate utilization system --- paralogs --- orthologs --- recombinant phospholipase A1 --- Yersinia pseudotuberculosis --- inclusion bodies --- fusion protein --- green fluorescent protein --- porin gene expression --- antibiotic stress --- phenotypic heterogeneity --- n/a --- HPLC-DAD-MS
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The G.B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far-Eastern Branch of the Russian Academy of Sciences (PIBOC FEB RAS) was founded in 1964 in Vladivostok in the Far East of Russia. Over many years, we have been carrying out studies on the natural products of both marine and terrestrial origin. In collaboration with many Russian and foreign scientists, we have investigated many hundreds of diverse biomolecules, including steroids and terpenoids, quinoid compounds and alkaloids, polysaccharides and lipids, enzymes and lectins, proteins, and peptides. The Institute has a collection of marine microorganisms (KMM) PIBOC, which includes more than 4000 strains of marine bacteria and more than 1000 strains of marine fungi. The biological activity of natural compounds is also being studied. This book includes the 14 manuscripts which covered almost all aspects of PIBOC research activity in the fields of bioorganic chemistry, biochemistry, organic synthesis of natural compounds, marine microbiology, and genetic engineering, and we hope it will provide interesting new information for scientists working in these fields.
Research & information: general --- polyhydroxylated steroids --- NMR spectra --- starfish --- Anthenoides laevigatus --- cytotoxicity --- soft agar assay --- kainic acid --- domoic acid --- dysiherbaine --- neodysiherbaine A --- marine bacteria --- whole genome sequence --- porin --- amino acids composition --- bilayer lipid membrane --- pore-forming activity --- spatial structure --- phlorotannins --- phlorethols --- anticancer activity --- colorectal cancer --- radiosensitizer --- radiotherapy --- 1,4-naphthoquinones --- quinoid compounds --- thioglycosides --- quinone-sugar conjugates --- cytotoxic activity --- antibiotic activity --- histochrome --- echinochrome A --- oxidative degradation --- HPLC-DAD-MS --- NMR --- actinoporin --- sea anemone --- Heteractis crispa --- anti-migratory activity --- glycosphingolipids --- cerebrosides --- peroxidation products --- structure elucidation --- allylic thioether --- ESI-MS --- GC-MS --- mass spectra --- glass sponge --- isomalabaricanes --- Stelletta sp. --- marine sponge --- terpenoid --- Cobetia amphilecti --- Cobetia litoralis --- Cobetia pacifica --- Cobetia marina --- Cobetia crustatorum --- identification markers --- alkaline phosphatase PhoA --- lanosterol 14-alpha demethylase --- flavonoids --- enzyme inhibition --- surface plasmon resonance --- spectral titration --- molecular docking --- Zobellia --- genomes --- polysaccharide lyase family 7 --- alginate utilization system --- paralogs --- orthologs --- recombinant phospholipase A1 --- Yersinia pseudotuberculosis --- inclusion bodies --- fusion protein --- green fluorescent protein --- porin gene expression --- antibiotic stress --- phenotypic heterogeneity --- polyhydroxylated steroids --- NMR spectra --- starfish --- Anthenoides laevigatus --- cytotoxicity --- soft agar assay --- kainic acid --- domoic acid --- dysiherbaine --- neodysiherbaine A --- marine bacteria --- whole genome sequence --- porin --- amino acids composition --- bilayer lipid membrane --- pore-forming activity --- spatial structure --- phlorotannins --- phlorethols --- anticancer activity --- colorectal cancer --- radiosensitizer --- radiotherapy --- 1,4-naphthoquinones --- quinoid compounds --- thioglycosides --- quinone-sugar conjugates --- cytotoxic activity --- antibiotic activity --- histochrome --- echinochrome A --- oxidative degradation --- HPLC-DAD-MS --- NMR --- actinoporin --- sea anemone --- Heteractis crispa --- anti-migratory activity --- glycosphingolipids --- cerebrosides --- peroxidation products --- structure elucidation --- allylic thioether --- ESI-MS --- GC-MS --- mass spectra --- glass sponge --- isomalabaricanes --- Stelletta sp. --- marine sponge --- terpenoid --- Cobetia amphilecti --- Cobetia litoralis --- Cobetia pacifica --- Cobetia marina --- Cobetia crustatorum --- identification markers --- alkaline phosphatase PhoA --- lanosterol 14-alpha demethylase --- flavonoids --- enzyme inhibition --- surface plasmon resonance --- spectral titration --- molecular docking --- Zobellia --- genomes --- polysaccharide lyase family 7 --- alginate utilization system --- paralogs --- orthologs --- recombinant phospholipase A1 --- Yersinia pseudotuberculosis --- inclusion bodies --- fusion protein --- green fluorescent protein --- porin gene expression --- antibiotic stress --- phenotypic heterogeneity
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