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Abiotic stress represents the main constraint for agriculture, affecting plant growth and productivity worldwide. Yield losses in agriculture will be potentiated in the future by global warming, increasing contamination, and reduced availability of fertile land. The challenge for agriculture of the present and future is that of increasing the food supply for a continuously growing human population under environmental conditions that are deteriorating in many areas of the world. Minimizing the effects of diverse types of abiotic stresses represents a matter of general concern. Research on all topics related to abiotic stress tolerance, from understanding the stress response mechanisms of plants to developing cultivars and crops tolerant to stress, is a priority. This Special Issue is focused on the physiological and molecular characterization of crop resistance to abiotic stresses, including novel research, reviews, and opinion articles covering all aspects of the responses and mechanisms of plant tolerance to abiotic. Contributions on physiological, biochemical, and molecular studies of crop responses to abiotic stresses; the description and role of stress-responsive genes; marker-assisted screening of stress-tolerant genotypes; genetic engineering; and other biotechnological approaches to improve crop tolerance were considered.
silicon --- strawberry --- total antioxidants --- drought --- stress responses --- arbuscular mycorrhizal fungus (AMF) --- Rhizophagus clarus --- flood --- plants --- hormonal homeostasis --- physiological activity --- drought tolerance --- LEA --- Tevang 1 maize --- tobacco --- xylem vessel --- water stress --- root anatomy --- vegetable crops --- stomatal conductance --- canopy temperature --- chlorophyll fluorescence --- SPAD --- common buckwheat --- cotyledon --- root --- drought stress --- transcriptome analysis --- alfalfa --- evaluation --- growth --- heat stress --- physiological traits --- sodium azide --- okra --- waterlogging stress --- antioxidants --- gene expression --- salinity --- sodium --- potassium --- ion homeostasis-transport determinants --- CBL gene family --- Provitamin A --- maize --- morphological --- physiological --- biochemical --- β-carotene --- Capsicum annuum L. --- salt stress --- salicylic acid --- yeast --- proline --- pomegranate --- transcriptome --- tissue-specific --- signaling transduction pathways --- transcription factors --- ultrastructure --- osmotic stress --- wheat --- barley --- summer maize --- female panicle --- Abiotic stress --- climate change --- combined drought and heat stress --- genetic resources --- landrace accessions --- coated-urea fertilizer --- humic acid --- lignosulfonate --- natural polymers --- seaweed extract --- aquaporin --- Brassica rapa --- gas exchange parameters --- root hydraulic conductance --- zinc --- ALA --- abiotic stress --- chlorophyll --- photosynthesis --- antioxidant enzyme --- tomato cultivars --- salinity tolerance --- antioxidant activity --- lycopene --- ascorbic acid --- total polyphenols content --- Capsicum annuum --- root structure --- root hairs --- phosphorus use efficiency --- P-starvation --- macrominerals --- nutrient --- breeding --- eggplant --- wild relative --- vegetative growth --- ion homeostasis --- osmolytes --- oxidative stress --- Phaseolus --- landrace --- seed --- germination --- genetic approach --- sustainable agriculture --- weeds --- natural herbicides --- secondary metabolites --- postemergence --- phytotoxicity --- abiotic stress biomarkers --- bean landraces --- plant breeding --- salt stress tolerance --- water deficit --- water stress tolerance --- tea plant --- cold stress --- chitosan oligosaccharide --- physiological response --- plant growth --- agriculture --- traditions --- pseudo-science --- lunar phases --- physics --- biology --- education --- flooding --- nutrient stress --- ROS
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Abiotic stress represents the main constraint for agriculture, affecting plant growth and productivity worldwide. Yield losses in agriculture will be potentiated in the future by global warming, increasing contamination, and reduced availability of fertile land. The challenge for agriculture of the present and future is that of increasing the food supply for a continuously growing human population under environmental conditions that are deteriorating in many areas of the world. Minimizing the effects of diverse types of abiotic stresses represents a matter of general concern. Research on all topics related to abiotic stress tolerance, from understanding the stress response mechanisms of plants to developing cultivars and crops tolerant to stress, is a priority. This Special Issue is focused on the physiological and molecular characterization of crop resistance to abiotic stresses, including novel research, reviews, and opinion articles covering all aspects of the responses and mechanisms of plant tolerance to abiotic. Contributions on physiological, biochemical, and molecular studies of crop responses to abiotic stresses; the description and role of stress-responsive genes; marker-assisted screening of stress-tolerant genotypes; genetic engineering; and other biotechnological approaches to improve crop tolerance were considered.
Research & information: general --- Biology, life sciences --- silicon --- strawberry --- total antioxidants --- drought --- stress responses --- arbuscular mycorrhizal fungus (AMF) --- Rhizophagus clarus --- flood --- plants --- hormonal homeostasis --- physiological activity --- drought tolerance --- LEA --- Tevang 1 maize --- tobacco --- xylem vessel --- water stress --- root anatomy --- vegetable crops --- stomatal conductance --- canopy temperature --- chlorophyll fluorescence --- SPAD --- common buckwheat --- cotyledon --- root --- drought stress --- transcriptome analysis --- alfalfa --- evaluation --- growth --- heat stress --- physiological traits --- sodium azide --- okra --- waterlogging stress --- antioxidants --- gene expression --- salinity --- sodium --- potassium --- ion homeostasis-transport determinants --- CBL gene family --- Provitamin A --- maize --- morphological --- physiological --- biochemical --- β-carotene --- Capsicum annuum L. --- salt stress --- salicylic acid --- yeast --- proline --- pomegranate --- transcriptome --- tissue-specific --- signaling transduction pathways --- transcription factors --- ultrastructure --- osmotic stress --- wheat --- barley --- summer maize --- female panicle --- Abiotic stress --- climate change --- combined drought and heat stress --- genetic resources --- landrace accessions --- coated-urea fertilizer --- humic acid --- lignosulfonate --- natural polymers --- seaweed extract --- aquaporin --- Brassica rapa --- gas exchange parameters --- root hydraulic conductance --- zinc --- ALA --- abiotic stress --- chlorophyll --- photosynthesis --- antioxidant enzyme --- tomato cultivars --- salinity tolerance --- antioxidant activity --- lycopene --- ascorbic acid --- total polyphenols content --- Capsicum annuum --- root structure --- root hairs --- phosphorus use efficiency --- P-starvation --- macrominerals --- nutrient --- breeding --- eggplant --- wild relative --- vegetative growth --- ion homeostasis --- osmolytes --- oxidative stress --- Phaseolus --- landrace --- seed --- germination --- genetic approach --- sustainable agriculture --- weeds --- natural herbicides --- secondary metabolites --- postemergence --- phytotoxicity --- abiotic stress biomarkers --- bean landraces --- plant breeding --- salt stress tolerance --- water deficit --- water stress tolerance --- tea plant --- cold stress --- chitosan oligosaccharide --- physiological response --- plant growth --- agriculture --- traditions --- pseudo-science --- lunar phases --- physics --- biology --- education --- flooding --- nutrient stress --- ROS
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Environmental abiotic stresses, such as extreme temperatures, drought, excess light, salinity, and nutrient deficiency, have detrimental effects on plant growth, development, and yield. Plants are equipped with various adaptation mechanisms to cope with such unfavorable conditions. Our understanding of plants’ abiotic stress responses is crucial to maintaining efficient plant productivity. This book on the responses of plants to environmental stresses is an attempt to find answers to several basic questions related to their adaptation and protective mechanisms against abiotic stresses. The following chapters of the book describe examples of plants’ protective strategies, which cover physiological, cellular, biochemical, and genomic mechanisms. This book is aimed for use by advanced students and researchers in the area of stress biology, plant molecular biology and physiology, agriculture, biochemistry, as well as environmental sciences.
Heterogeneous water stress --- Phyllostachys edulis --- Rhizome --- Vascular bundle --- Stress Signal --- Physiological characteristics --- isoprene --- ocimene --- heat stress --- water stress --- ramie (Boehmeria nivea (L.) Gaudich) --- transcriptome --- nitrogen deficiency --- resilience --- nitrogen-use efficiency --- eggplant --- heat shock factor --- gene family --- expression profile --- abiotic stress --- Malus. ‘Prairifire’ --- photosynthetic characteristics --- chlorophyll a fluorescence --- 2-dimensional electrophoresis --- diurnal regulation --- OsGI --- rice --- U-box E3 ligase --- barley --- ABC gene family --- gene expression --- alarm photosynthesis --- Antarctic --- oxalate oxidase --- Elymus sibiricus, seed aging --- isobaric tandem mass tag labeling --- reactive oxygen species --- parallel reaction monitoring --- Dendrobium catenatum --- superoxide dismutase (SOD) --- stresses --- antioxidative enzyme activity --- low pH --- proline --- protein --- wheat --- WRKY transcription factor --- gene structural characteristics --- regulatory mechanism --- drought --- salinity --- heat --- cold --- ultraviolet radiation --- rainfed --- irrigated --- Gossypium hirsutum --- antioxidant activity --- growth inhibition --- ion homeostasis --- salt stress --- rhizoboxes --- gaseous exchange --- sub-Saharan Africa --- root length density
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This book presents the advances in plant salinity stress and tolerance, including mechanistic insights revealed using powerful molecular tools and multi-omics and gene functions studied by genetic engineering and advanced biotechnological methods. Additionally, the use of plant growth-promoting rhizobacteria in the improvement of plant salinity tolerance and the underlying mechanisms and progress in breeding for salinity-tolerant rice are comprehensively discussed. Clearly, the published data have contributed to the significant progress in expanding our knowledge in the field of plant salinity stress and the results are valuable in developing salinity-stress-tolerant crops; in benefiting their quality and productivity; and eventually, in supporting the sustainability of the world food supply.
watermelon --- salt stress --- RNA-seq --- amino acids --- endocytosis --- Arabidopsis thaliana --- halophyte --- high-affinity potassium transporter (HKT) --- Na+ transporter --- salt tolerance --- Sporobolus virginicus --- aquaporins --- barley --- ion transport --- oocytes --- plasma membrane intrinsic proteins (PIPs) --- GmbZIP15 --- transcription factor --- drought stress --- soybean --- biotechnology breeding --- high-throughput sequencing --- QTLs --- rice --- halophytic wild barley --- salinity --- osmotic stress --- metabolome --- transcriptome --- ionome --- stress adaptation --- Hordeum marinum --- aquaporin --- Zygophyllum xanthoxylum --- plant growth --- abiotic stress --- sensing --- signaling --- transcription factors --- osmoregulation --- antioxidation --- ion homeostasis --- jasmonates --- jasmonate signaling pathway --- crosstalk --- exogenous jasmonate applications --- GWAS --- PGPR --- ACC deaminase --- seed priming --- IAA --- cell wall integrity --- cell wall sensor --- LRXs --- CrRLK1Ls --- Millettia pinnata --- calmodulin-like --- heterologous expression --- halophiles --- plant growth-promoting rhizobacteria (PGPR) --- RNA sequence analysis (RNA-seq) --- quantitative reverse transcriptase PCR (qRT-PCR) --- n/a
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This book presents the advances in plant salinity stress and tolerance, including mechanistic insights revealed using powerful molecular tools and multi-omics and gene functions studied by genetic engineering and advanced biotechnological methods. Additionally, the use of plant growth-promoting rhizobacteria in the improvement of plant salinity tolerance and the underlying mechanisms and progress in breeding for salinity-tolerant rice are comprehensively discussed. Clearly, the published data have contributed to the significant progress in expanding our knowledge in the field of plant salinity stress and the results are valuable in developing salinity-stress-tolerant crops; in benefiting their quality and productivity; and eventually, in supporting the sustainability of the world food supply.
Research & information: general --- Biology, life sciences --- watermelon --- salt stress --- RNA-seq --- amino acids --- endocytosis --- Arabidopsis thaliana --- halophyte --- high-affinity potassium transporter (HKT) --- Na+ transporter --- salt tolerance --- Sporobolus virginicus --- aquaporins --- barley --- ion transport --- oocytes --- plasma membrane intrinsic proteins (PIPs) --- GmbZIP15 --- transcription factor --- drought stress --- soybean --- biotechnology breeding --- high-throughput sequencing --- QTLs --- rice --- halophytic wild barley --- salinity --- osmotic stress --- metabolome --- transcriptome --- ionome --- stress adaptation --- Hordeum marinum --- aquaporin --- Zygophyllum xanthoxylum --- plant growth --- abiotic stress --- sensing --- signaling --- transcription factors --- osmoregulation --- antioxidation --- ion homeostasis --- jasmonates --- jasmonate signaling pathway --- crosstalk --- exogenous jasmonate applications --- GWAS --- PGPR --- ACC deaminase --- seed priming --- IAA --- cell wall integrity --- cell wall sensor --- LRXs --- CrRLK1Ls --- Millettia pinnata --- calmodulin-like --- heterologous expression --- halophiles --- plant growth-promoting rhizobacteria (PGPR) --- RNA sequence analysis (RNA-seq) --- quantitative reverse transcriptase PCR (qRT-PCR)
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Environmental abiotic stresses, such as extreme temperatures, drought, excess light, salinity, and nutrient deficiency, have detrimental effects on plant growth, development, and yield. Plants are equipped with various adaptation mechanisms to cope with such unfavorable conditions. Our understanding of plants’ abiotic stress responses is crucial to maintaining efficient plant productivity. This book on the responses of plants to environmental stresses is an attempt to find answers to several basic questions related to their adaptation and protective mechanisms against abiotic stresses. The following chapters of the book describe examples of plants’ protective strategies, which cover physiological, cellular, biochemical, and genomic mechanisms. This book is aimed for use by advanced students and researchers in the area of stress biology, plant molecular biology and physiology, agriculture, biochemistry, as well as environmental sciences.
Medicine --- Heterogeneous water stress --- Phyllostachys edulis --- Rhizome --- Vascular bundle --- Stress Signal --- Physiological characteristics --- isoprene --- ocimene --- heat stress --- water stress --- ramie (Boehmeria nivea (L.) Gaudich) --- transcriptome --- nitrogen deficiency --- resilience --- nitrogen-use efficiency --- eggplant --- heat shock factor --- gene family --- expression profile --- abiotic stress --- Malus. ‘Prairifire’ --- photosynthetic characteristics --- chlorophyll a fluorescence --- 2-dimensional electrophoresis --- diurnal regulation --- OsGI --- rice --- U-box E3 ligase --- barley --- ABC gene family --- gene expression --- alarm photosynthesis --- Antarctic --- oxalate oxidase --- Elymus sibiricus, seed aging --- isobaric tandem mass tag labeling --- reactive oxygen species --- parallel reaction monitoring --- Dendrobium catenatum --- superoxide dismutase (SOD) --- stresses --- antioxidative enzyme activity --- low pH --- proline --- protein --- wheat --- WRKY transcription factor --- gene structural characteristics --- regulatory mechanism --- drought --- salinity --- heat --- cold --- ultraviolet radiation --- rainfed --- irrigated --- Gossypium hirsutum --- antioxidant activity --- growth inhibition --- ion homeostasis --- salt stress --- rhizoboxes --- gaseous exchange --- sub-Saharan Africa --- root length density
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Salt stress is one of the most damaging abiotic stresses because most crop plants are susceptible to salinity to different degrees. According to the FAO, about 800 million Has of land are affected by salinity worldwide. Unfortunately, this situation will worsen in the context of climate change, where there will be an overall increase in temperature and a decrease in average annual rainfall worldwide. This Special Issue presents different research works and reviews on the response of plants to salinity, focused from different points of view: physiological, biochemical, and molecular levels. Although an important part of the studies on the response to salinity have been carried out with Arabidopsis plants, the use of other species with agronomic interest is also notable, including woody plants. Most of the conducted studies in this Special Issue were focused on the identification and characterization of candidate genes for salt tolerance in higher plants. This identification would provide valuable information about the molecular and genetic mechanisms involved in the salt tolerance response, and it also supplies important resources to breeding programs for salt tolerance in plants.
soluble nutrients --- transcription factor --- n/a --- CDPK --- salicylic acid --- antioxidant enzymes --- light saturation point --- phytohormone --- ion homeostasis --- antioxidant systems --- photosynthesis --- Chlamydomonas reinhardtii --- high salinity --- nitric oxide --- poplars (Populus) --- root activity --- abiotic stresses --- transcriptional activator --- germination --- ABA --- transcriptome --- mandelonitrile --- redox homeostasis --- association mapping. --- redox signalling --- osmotic stress --- flax --- strigolactones --- salt tolerance --- nucleolin --- CaDHN5 --- photosystem --- EST-SSR --- NMT --- Sapium sebiferum --- Gossypium arboretum --- SOS --- Brassica napus --- SnRK2 --- HKT1 --- grapevine --- transcription factors --- cucumber --- underpinnings of salt stress responses --- abiotic stress --- Arabidopsis thaliana --- RNA-seq --- halophytes --- single nucleotide polymorphisms --- dehydrin --- J8-1 plum line --- chlorophyll fluorescence --- natural variation --- hydrogen peroxide --- salt stress --- lipid peroxidation --- ROS detoxification --- ROP --- molecular mechanisms --- cell membrane injury --- booting stage --- ascorbate cycle --- banana (Musa acuminata L.) --- iTRAQ quantification --- ROS --- Na+ --- Capsicum annuum L. --- bZIP transcription factors --- multiple bioactive constituents --- NaCl stress --- physiological changes --- VOZ --- transcriptional regulation --- genome-wide identification --- Apocyni Veneti Folium --- impairment of photosynthesis --- salt-stress --- Oryza sativa --- reactive oxygen species --- lipid accumulation --- polyamines --- multivariate statistical analysis --- DEUs --- salinity --- TGase --- Salt stress --- Prunus domestica --- proteomics --- Arabidopsis --- RNA binding protein --- rice --- glycophytes --- SsMAX2 --- drought --- genome-wide association study --- transcriptome analysis --- signal pathway --- melatonin --- MaROP5g
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As sessile organisms, plants have to cope with a multitude of natural and anthropogenic forms of stress in their environment. Due to their longevity, this is of particular significance for trees. As a consequence, trees develop an orchestra of resilience and resistance mechanisms to biotic and abiotic stresses in order to support their growth and development in a constantly changing atmospheric and pedospheric environment. The objective of this Special Issue of Forests is to summarize state-of-art knowledge and report the current progress on the processes that determine the resilience and resistance of trees from different zonobiomes as well as all forms of biotic and abiotic stress from the molecular to the whole tree level.
pure stands --- n/a --- ion relation --- Heterobasidion annosum --- salicylic acid --- antioxidant enzymes --- antioxidant activity --- Luquasorb --- intrinsic water-use efficiency --- Greece --- Pinus koraiensis Sieb. et Zucc. --- ion homeostasis --- photosynthesis --- Pinus massoniana --- Stockosorb --- water relations --- Norway spruce --- rubber tree --- hydrophilic polymers --- drought stress --- ion relationships --- Carpinus betulus --- tree rings --- N nutrition --- disturbance --- Populus simonii Carr. (poplar) --- infection --- subcellular localization --- basal area increment --- mixed stands --- photosynthetic responses --- Aleppo pine --- water potential --- elevation gradient --- living cell --- physiological response --- antioxidant enzyme activity --- ion contents --- signal network --- expression --- soil N --- GA-signaling pathway --- differentially expressed genes --- Ca2+ signal --- climate --- ecophysiology --- Robinia pseudoacacia L. --- Heterobasidion parviporum --- mid-term --- plant tolerance --- canopy conductance --- DELLA --- tapping panel dryness --- osmotic adjustment substances --- abiotic stress --- wood formation --- malondialdehyde --- salinity treatments --- organic osmolytes --- bamboo forest --- non-structural carbohydrate --- Abies alba Mill. --- tree --- salt stress --- Populus euphratica --- proline --- nutrition --- Carpinus turczaninowii --- plasma membrane Ca2+ channels --- gene regulation --- pathogen --- TCP --- forest type --- functional analysis --- Fraxinus mandshurica Rupr. --- long-term drought --- defense response --- cold stress --- silicon fertilization --- gas exchange --- Fagus sylvatica L. --- glutaredoxin --- water availability --- 24-epiBL application --- Konjac glucomannan --- leaf properties --- reactive oxygen species --- sap flow --- ?13C --- salinity --- morphological indices --- chloroplast ultrastructure --- Moso Bamboo (Phyllostachys edulis) --- drought --- soluble sugar --- molecular cloning --- starch --- growth
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Overall, the 19 contributions in this Special Issue “Plant Responses and Tolerance to Salt Stress: Physiological and Molecular Interventions” discuss the various aspects of salt stress responses in plants. It also discusses various mechanisms and approaches to conferring salt tolerance on plants. These types of research studies provide further directions in the development of crop plants for the saline environment in the era of climate change.
CPA gene family --- RsNHX1 --- over-expression --- virus-induced gene silence --- salt resistance --- radish --- 14-3-3 gene family --- Triticum aestivum L. --- bioinformatics analysis --- salt tolerance --- protein-protein interactions --- Populus simonii × P. nigra --- PsnNAC036 --- transcription factor --- salt stress --- HT tolerance --- ion transport --- osmotic homeostasis --- hormone mediation --- cell wall regulation --- salt adaptation --- proteomics --- microtubules --- tubulin --- phenolic metabolites --- lemon balm --- chlorophyll fluorescence --- medicinal plants --- secondary metabolites --- abiotic elicitors --- salinity --- betaine aldehyde dehydrogenase 1 (BADH1) --- domestication --- cultivated rice --- wild rice --- Hordeum vulgare L. --- RNA-seq analysis --- differentially expressed genes --- tolerance --- candidate genes --- C3–CAM intermediate --- common ice plant --- Mesembryanthemum crystallinum --- osmotic stress --- abiotic stress --- antioxidant defense --- climate change --- hydrogen peroxide --- lipid peroxidation --- oxidative stress --- phytohormones --- stress signaling --- mulberry --- TMT proteomics --- phenylpropanoid metabolism --- apoplast --- functional screening --- Hordeum vulgare --- seedling --- halophyte species --- NADPH oxidases --- NOX --- respiratory burst oxidase homolog RBOH gene expression --- saline adaptations --- C2H2 zinc finger protein --- heterologous expression --- Millettia pinnata --- thaumatin-like proteins (TLPs) --- bolTLP1 --- broccoli --- drought stress --- antioxidants --- carbohydrates --- carotenoids --- xanthophyll cycle --- osmoprotectants --- ROS-scavengers --- α-/γ-tocopherols --- quantitative trait locus (QTL) --- association analysis --- marker-assisted selection (MAS) --- rice (Oryza sativa L.) --- hydroxyindole-O-methyltransferase gene --- melatonin --- ROS --- ABA --- ion homeostasis --- amino acids --- Malus domestica --- calcium --- calcineurin B-like proteins --- Na+ accumulation --- n/a --- C3-CAM intermediate
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Mitochondria are subcellular organelles evolved by the endosymbiosis of bacteria with eukaryotic cells. They are the main source of ATP in the cell and engaged in other aspects of cell metabolism and cell function, including the regulation of ion homeostasis, cell growth, redox status, and cell signaling. Due to their central role in cell life and death, mitochondria are also involved in the pathogenesis and progression of human diseases/conditions, including neurodegenerative and cardiovascular disorders, cancer, diabetes, inflammation, and aging. However, despite the increasing number of studies, precise mechanisms whereby mitochondria are involved in the regulation of basic physiological functions, as well as their role in the cell under pathophysiological conditions, remain unknown. A lack of in-depth knowledge of the regulatory mechanisms of mitochondrial metabolism and function, as well as interplay between the factors that transform the organelle from its role in pro-survival to pro-death, have hindered the development of new mitochondria-targeted pharmacological and conditional approaches for the treatment of human diseases. This book highlights the latest achievements in elucidating the role of mitochondria under physiological conditions, in various cell/animal models of human diseases, and in patients.
hypoglycemia --- sodium dichloroacetate --- pyruvate dehydrogenase kinase --- pyruvate dehydrogenase --- oxidative stress --- neuron death --- cholangiocellular carcinoma --- mitochondria --- energy metabolism --- oxidative phosphorylation --- 4-HNE --- DRP1 --- ERK1/2 --- hippocampus --- JNK --- mitochondrial dynamics --- PKA --- protein phosphatases --- TUNEL --- DDE --- high-fat diet --- mitochondrial UCP2 --- ROS --- antioxidant system --- uncoupling protein --- mitochondria: energy metabolism --- lipid handling --- fatty acid oxidation --- potassium channel --- reactive oxygen species --- antioxidants --- life span --- aging --- BKCa channels --- pravastatin --- gemfibrozil --- liver --- colon --- mitochondrial function --- cyclosporin A --- mitochondria calcium buffering --- mitochondria bioenergetics --- mitochondria permeability transition pore --- inorganic phosphate --- hepatic fibrogenesis --- HtrA2/Omi --- reactive oxygen species stress --- mitochondrial homeostasis --- complex I (CI) deficiency --- metabolome and proteome profiling --- reactive oxygen species (ROS) --- respirasome assembly --- electron tunneling (ET) --- perilipin 5 --- lipid droplet --- H9c2 cardiomyoblasts --- adenine nucleotide translocase --- respiratory supercomplexes --- ETC complexes --- dentate granule cell --- epilepsy --- hyperforin --- LONP1 --- neuroprotection --- pilocarpine --- seizure --- siRNA --- cardioprotection --- mitochondrial permeability transition pores --- mitochondrial connexin 43 --- cardiolipin --- iron overload --- hepcidin --- transferrin --- ferritin --- ZIP --- inflammation --- mtDNA --- mitochondrial dysfunction --- muscle aging --- physical performance --- LHON --- Siberian population --- ancient mutation --- specific genetic background --- apoptosis --- human amniotic membrane --- mitochondrial cell death --- BAX --- BCL-2 --- tensile strength --- mitochondrial gene expression --- mtDNA transcription --- mtRNA --- post-transcriptional mtRNA processing --- dsRNA --- innate immunity --- interferon response --- amino acid neurotransmitter --- cerebellar amino acid metabolism --- hypoxia --- 2-oxoglutarate dehydrogenase --- tricarboxylic acid cycle --- heart --- cytoskeletal proteins --- mitochondrial interactions --- plectin --- tubulin beta --- signaling --- GW9662 --- ischemia reperfusion injury --- Langendorff --- myocardial --- pioglitazone --- redox state --- rosiglitazone --- TZD --- uncoupling --- ADP/ATP carrier --- KmADP --- dextran --- morphology --- cardiomyocytes --- telomere length --- telomerase activity --- development --- regeneration --- intranuclear mitochondria --- healthy cells --- electron and confocal microscopy --- signaling pathways --- ion homeostasis --- human diseases
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