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The purpose of this Special Issue is to provide a thorough and up-to-date presentation of research investigating the impact of coffee and/or caffeine intake on various health outcomes. Areas of interest include, but are not limited to, the following topics: Human clinical trials of coffee or caffeine use in relation to disease or intermediate phenotypes. Epidemiological studies of habitual coffee or caffeine intake in relation to human health, among the general public, as well as, among special populations (i.e., children, pregnant women, diabetics, cancer patients, hypertensives, etc.). Mechanisms of action of nutrients and other bioactive components of coffee/caffeine. Studies integrating genetic or physiological markers of coffee/caffeine intake to investigations of coffee and health.

coronary artery disease --- n/a --- lipids --- NADH dehydrogenase --- tea --- tinnitus --- safety --- transcriptomics --- ergogenic --- guidelines --- myocardial perfusion --- placebo --- Caffeine --- risk factors --- lysophosphatidylcholine --- pregnancy --- assisted reproduction techniques --- population --- adenosine --- liver fibrosis --- coffee consumption --- cognitive --- causation --- supplement --- mate --- adult --- gene expression --- wine --- lipidomics --- chocolate --- exercise --- protection --- Suicide --- dipyridamole --- regadenoson --- live birth --- hearing --- pharmacological ergogenic aid --- behavior --- cardiovascular disease --- gene-diet interaction --- whole-blood --- sex --- health --- systematic review --- causality --- genetic epidemiology --- implantation --- pharmacogenomics --- cognitions --- ergogenic aid --- time trial performance --- CYP1A2 --- aging --- phenolic --- country --- caffeine intake --- serum chloride levels --- polymorphism --- responders --- intoxication --- trial --- epidemiological methods --- bias --- adenosine receptor --- longevity --- did not respond --- energy drinks --- biomarkers --- individual responses --- Mendelian Randomization --- public policy --- anxiety --- the Norwegian Women and Cancer Cohort (NOWAC) --- ADORA2A --- clinical pregnancy --- caffeine metabolism --- caffeine intoxication --- cohort study --- mood --- mRNA --- alcohol consumption --- epidemiology --- caffeine --- expectancy --- accidental death --- European Prospective Investigation into Cancer and Nutrition --- cognition --- consumption --- HIV-HCV co-infection --- cytochrome P450 --- chlorogenic acids --- soda --- 24-h dietary recall --- coffee --- depression --- sport --- age