Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

neuroimmunology --- central nervous system --- translational medicine --- multiple sclerosis --- neurodegeneration --- immune system --- biomarkers --- immunotherapeutics

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Medicine --- Neurology & clinical neurophysiology --- neuroimmunology --- central nervous system --- translational medicine --- multiple sclerosis --- neurodegeneration --- immune system --- biomarkers --- immunotherapeutics

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Designing immunotherapeutics, drugs, and anti-inflammatory reagents has been at the forefront of autoimmune research, in particular multiple sclerosis, for over 20 years. Delivery methods that are used to modulate effective and long-lasting immune responses have been the major focus. This Special Issue focused on delivery methods to be used for vaccines, immunotherapeutic approaches, drug design, and anti-inflammatories and their outcomes in preclinical studies and clinical trials.

Medicine --- multiple sclerosis --- inflammation --- oxidative --- biomarker --- sample size --- autoimmune encephalitis --- plasma exchange --- autoimmunity --- immunotherapeutics --- clinical outcomes --- major depression --- bupropion --- S-adenosylmethionine --- vitamin D3 --- yoga --- craniopharyngioma --- fractionated stereotactic radiation treatments --- sphenoid sinusitis --- cranial nerve-VI palsy --- autoimmune diseases --- immune thrombocytopenic purpura --- alemtuzumab --- antibodies against GluR3 peptide --- cognitive impairment --- diagnosis --- neuropsychological assessment --- short intracortical inhibition --- intracortical facilitation --- fampridine --- walking disability --- TSPAN32 --- tetraspanins --- cellular immunity --- memory T cells --- tDCS --- neuroimaging --- positron emission tomography --- cerebral blood flow --- probiotics --- Streptococcus thermophilus --- ST285 --- MBP83–99 peptide --- mannan --- immune modulation --- agonist peptide --- gut microbiome --- gut–brain axis --- metagenomics --- disease-modifying treatments --- MS --- vaccine --- immunomodulation --- carriers --- B cell receptor --- delivery methods --- immunotherapy --- monoclonal antibodies --- T cell receptor --- tolerance --- diagnostic markers --- immunoglobulins --- kappa --- free light chains --- antigen-specific immunotherapies --- tolerogenic vaccines --- tolerance induction --- central nervous system --- myelin peptides --- myelin basic protei --- proteolipid protein --- myelin oligodendrocyte glycoprotein --- nanotechnology --- drug delivery nanosystems --- lipids --- polymers --- vaccines --- nanoparticles --- antigen-specific immunotherapy --- experimental autoimmune encephalomyelitis --- neurodegeneration --- chloroquine --- EAE --- dendritic cells --- microglia --- astrocytes --- oligodendrocytes --- conformational analysis --- peptides --- altered peptide ligands --- NMR spectroscopy --- NOE-constraints --- molecular dynamic --- trimolecular complex --- Multiple Sclerosis --- early-onset --- adult-onset --- Human Leucocyte Antigens --- immunogenetics --- clinical phenotype --- clinical outcome --- therapeutics --- antibody detection --- ELISA --- multivalency --- N-glucosylated peptide epitopes --- peptide --- conjugation --- MOG35-55 --- Graphite/SiO2 electrode --- voltammetry --- HPLC --- MS drugs